| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphoglycerate dehydrogenase|This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 26227) |
| External Link | https://ncbi.nlm.nih.gov/gene/26227 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PHGDH gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0123467 |
| MAP7 | microtubule-associated protein 7 | 0.0119005 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.0102741 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00858233 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00845276 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00838587 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00830935 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.00724636 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.0072097 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00717282 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00713254 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00713248 |
| TOX3 | TOX high mobility group box family member 3 | 0.00708145 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00676064 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00666321 |
| ESR1 | estrogen receptor 1 | 0.00651847 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00611016 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00609629 |
| TGM2 | transglutaminase 2 | 0.00598788 |
| CD163 | CD163 molecule | 0.00589298 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00584203 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00584125 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00571409 |
| CD14 | CD14 molecule | 0.00569345 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00564256 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00552828 |
| CLU | clusterin | 0.00551809 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00550066 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00545458 |
| HHEX | hematopoietically expressed homeobox | 0.00538893 |
| CAV2 | caveolin 2 | 0.00537776 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00527501 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00526852 |
| SRGN | serglycin | 0.00526659 |
| PLXNC1 | plexin C1 | 0.00526658 |
| CLIC2 | chloride intracellular channel 2 | 0.00526486 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00523138 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00521975 |
| APOD | apolipoprotein D | 0.00519465 |
| CARD10 | caspase recruitment domain family, member 10 | 0.00518908 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00516668 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00515682 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00514278 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00513923 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.00512898 |
| MFAP5 | microfibrillar associated protein 5 | 0.00511879 |
| HMG20B | high mobility group 20B | 0.00508557 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00506963 |
| MEIS2 | Meis homeobox 2 | 0.00506602 |
| CFD | complement factor D (adipsin) | 0.00501437 |
| SYNM | synemin, intermediate filament protein | 0.00496969 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00495605 |
| KRT23 | keratin 23, type I | 0.00494071 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00493528 |
| JAG1 | jagged 1 | 0.004867 |
| LYZ | lysozyme | 0.00485375 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | 0.00485234 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00483524 |
| ADCY9 | adenylate cyclase 9 | 0.00482704 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00476708 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00473315 |
| NRCAM | neuronal cell adhesion molecule | 0.00473022 |
| PMP22 | peripheral myelin protein 22 | 0.00470205 |
| XCL1 | chemokine (C motif) ligand 1 | 0.00466308 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0046564 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00464155 |
| METRN | meteorin, glial cell differentiation regulator | 0.00464131 |
| IRS1 | insulin receptor substrate 1 | 0.00460657 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00460227 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00459804 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00458404 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00458132 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00454835 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00454668 |
| PERP | PERP, TP53 apoptosis effector | 0.00454486 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00453869 |
| RBPMS | RNA binding protein with multiple splicing | 0.00453356 |
| APMAP | adipocyte plasma membrane associated protein | 0.00453174 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00451671 |
| RGS13 | regulator of G-protein signaling 13 | 0.00451147 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | 0.00450828 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00448088 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00447795 |
| EFNB2 | ephrin-B2 | 0.00447643 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00446974 |
| ATMIN | ATM interactor | 0.00446241 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00445676 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00445328 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00443689 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00443362 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00440334 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00439305 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00439116 |
| LY75 | lymphocyte antigen 75 | 0.00439072 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00436475 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00427534 |
| H1-2 | H1.2 linker histone, cluster member | 0.00426236 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00426228 |
| TLK2 | tousled-like kinase 2 | 0.00426134 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00423736 |
| CST7 | cystatin F (leukocystatin) | 0.00420992 |
| CDC20 | cell division cycle 20 | 0.00420051 |
| TSPAN12 | tetraspanin 12 | 0.0041983 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00417835 |
| IL18 | interleukin 18 | 0.00417437 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 | 0.00416076 |
| CCDC92 | coiled-coil domain containing 92 | 0.004155 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.00414614 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | 0.00413826 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0041305 |
| TESK1 | testis-specific kinase 1 | 0.00411185 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | 0.00410213 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.00409944 |
| TRIM37 | tripartite motif containing 37 | 0.00409801 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00409736 |
| XK | X-linked Kx blood group | 0.0040898 |
| MYOF | myoferlin | 0.00407938 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00407534 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.00406902 |
| RAI2 | retinoic acid induced 2 | 0.00406655 |
| PCLAF | PCNA clamp associated factor | 0.00406059 |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) | 0.00404566 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00403864 |
| RPIA | ribose 5-phosphate isomerase A | 0.00402686 |
| HOXB2 | homeobox B2 | 0.00402315 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00401296 |
| RIN2 | Ras and Rab interactor 2 | 0.00400972 |
| PLN | phospholamban | 0.00399123 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.00396643 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00396643 |
| LUM | lumican | 0.00396472 |
| NBEA | neurobeachin | 0.00396382 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.00396203 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00394138 |
| PLPP2 | phospholipid phosphatase 2 | 0.00393327 |
| PLCB4 | phospholipase C, beta 4 | 0.00393207 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.0039278 |
| NPTN | neuroplastin | 0.0039274 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00392658 |
| VEGFC | vascular endothelial growth factor C | 0.00388564 |
| S100A8 | S100 calcium binding protein A8 | 0.00388561 |
| BAD | BCL2-associated agonist of cell death | 0.00387538 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00387314 |
| TFEC | transcription factor EC | 0.00386932 |
| VLDLR | very low density lipoprotein receptor | 0.00386816 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00386207 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00384385 |
| STXBP2 | syntaxin binding protein 2 | 0.00383925 |
| PAX5 | paired box 5 | 0.00383805 |
| ASPN | asporin | 0.00381253 |
| AKAP1 | A kinase (PRKA) anchor protein 1 | 0.00380525 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | 0.00380192 |
| TYROBP | TYRO protein tyrosine kinase binding protein | 0.00379878 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00379175 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00379079 |
| NKG7 | natural killer cell granule protein 7 | 0.00378362 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00377965 |
| GUSB | glucuronidase, beta | 0.00377931 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 | 0.00377665 |
| DES | desmin | 0.00377488 |
| COG7 | component of oligomeric golgi complex 7 | 0.00377117 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.00375832 |
| TNS3 | tensin 3 | 0.00375787 |
| UBE3C | ubiquitin protein ligase E3C | 0.00374523 |
| TMEM106B | transmembrane protein 106B | 0.00373883 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 0.00373688 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00372529 |
| FAM3C | family with sequence similarity 3, member C | 0.00372469 |
| MTCL1 | microtubule crosslinking factor 1 | 0.00372339 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | 0.00372195 |
| LAMB1 | laminin, beta 1 | 0.00371695 |
| CAVIN1 | caveolae associated protein 1 | 0.00371647 |
| TSPAN4 | tetraspanin 4 | 0.00371372 |
| MACROD1 | MACRO domain containing 1 | 0.0036975 |
| HNMT | histamine N-methyltransferase | 0.00368315 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00367087 |
| C3 | complement component 3 | 0.00366704 |
| PLXND1 | plexin D1 | 0.00366626 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00366534 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0036632 |
| TUBB6 | tubulin, beta 6 class V | 0.00365892 |
| KIF20A | kinesin family member 20A | 0.00365882 |
| PLXNA1 | plexin A1 | 0.00365067 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.00364669 |
| CADM1 | cell adhesion molecule 1 | 0.00363166 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0036289 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | 0.00362835 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00362828 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00362583 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0036163 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00361448 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.00360886 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | 0.00359513 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.00358694 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00358169 |
| SEC24A | SEC24 family member A | 0.00355671 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00354717 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00354697 |
| RRM2 | ribonucleotide reductase M2 | 0.00354253 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00353738 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.00353334 |
| PCNA | proliferating cell nuclear antigen | 0.00352791 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00352576 |
| TFR2 | transferrin receptor 2 | 0.00351524 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | 0.00351181 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00350991 |
| BCL2L1 | BCL2-like 1 | 0.00350214 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) | 0.00350141 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.00350125 |
| PFDN4 | prefoldin subunit 4 | 0.00349822 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00349202 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00348903 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00348597 |
| PEG10 | paternally expressed 10 | 0.0034841 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00348045 |
| LEPR | leptin receptor | 0.00347984 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00347913 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00347703 |
| USP32P2 | ubiquitin specific peptidase 32 pseudogene 2 | 0.00347481 |
| CDC34 | cell division cycle 34 | 0.00347291 |
| MITF | microphthalmia-associated transcription factor | 0.00346937 |
| GATA2 | GATA binding protein 2 | 0.00346825 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00346758 |
| HMBS | hydroxymethylbilane synthase | 0.00346558 |
| ZNF512B | zinc finger protein 512B | 0.00346236 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.00345806 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.00345552 |
| TBC1D30 | TBC1 domain family, member 30 | 0.00345262 |
| MYO1D | myosin ID | 0.00344825 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00343601 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00343413 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00342652 |
| MED23 | mediator complex subunit 23 | 0.00342127 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.0034195 |
| CDK13 | cyclin-dependent kinase 13 | 0.00341229 |
| DUSP3 | dual specificity phosphatase 3 | 0.00340318 |
| ATP5MF | ATP synthase membrane subunit f | 0.00339091 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | 0.00338603 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.00338492 |
| MATN2 | matrilin 2 | 0.00338051 |
| KYNU | kynureninase | 0.00337757 |
| HIST1H2AE | histone cluster 1, H2ae | 0.00337395 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00336394 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00336212 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00335994 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00335506 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00335466 |
| PDCD6 | programmed cell death 6 | 0.00334995 |
| ELAC2 | elaC ribonuclease Z 2 | 0.00334828 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PHGDH | phosphoglycerate dehydrogenase | -0.0135569 |
| ASS1 | argininosuccinate synthase 1 | -0.00998708 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00982992 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00979603 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00903141 |
| TSPAN8 | tetraspanin 8 | -0.00895047 |
| BEX1 | brain expressed, X-linked 1 | -0.0085645 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00851848 |
| MT1E | metallothionein 1E | -0.00850513 |
| MAL | mal, T-cell differentiation protein | -0.00837024 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00832855 |
| IFI44 | interferon-induced protein 44 | -0.00790475 |
| BTG3 | BTG family, member 3 | -0.00755259 |
| IFI44L | interferon-induced protein 44-like | -0.00745743 |
| S100A2 | S100 calcium binding protein A2 | -0.00735835 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00694663 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00691112 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00649427 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00640866 |
| PITX3 | paired-like homeodomain 3 | -0.00613127 |
| MT1H | metallothionein 1H | -0.00609566 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00602021 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00594282 |
| MX1 | MX dynamin-like GTPase 1 | -0.00592359 |
| TAGLN2 | transgelin 2 | -0.00587004 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00586892 |
| MT1G | metallothionein 1G | -0.00584917 |
| SIRT3 | sirtuin 3 | -0.00582955 |
| MME | membrane metallo-endopeptidase | -0.00581357 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00577521 |
| NPTX2 | neuronal pentraxin II | -0.00575258 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00570839 |
| CLDN10 | claudin 10 | -0.00564143 |
| ADD3 | adducin 3 (gamma) | -0.005604 |
| ATF3 | activating transcription factor 3 | -0.00551761 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.00551534 |
| MT1F | metallothionein 1F | -0.00551457 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00550631 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.00549569 |
| KRT5 | keratin 5, type II | -0.00545661 |
| ECM1 | extracellular matrix protein 1 | -0.00541404 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00536076 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.00535244 |
| NSG1 | neuron specific gene family member 1 | -0.0053494 |
| LCN2 | lipocalin 2 | -0.00530024 |
| IL1RN | interleukin 1 receptor antagonist | -0.0052748 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00527194 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00519294 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00514886 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00513329 |
| TSPAN1 | tetraspanin 1 | -0.00506906 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.0050306 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00502245 |
| FOLR1 | folate receptor 1 (adult) | -0.00501335 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00497943 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00497381 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00497134 |
| NREP | neuronal regeneration related protein | -0.00496471 |
| TYRP1 | tyrosinase-related protein 1 | -0.00490294 |
| TMSB15A | thymosin beta 15a | -0.00489106 |
| MT2A | metallothionein 2A | -0.00488248 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00485907 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00485386 |
| TMEM45A | transmembrane protein 45A | -0.00478821 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00470946 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.0047025 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.00470219 |
| ENO1 | enolase 1, (alpha) | -0.00469993 |
| CBS | cystathionine-beta-synthase | -0.00469859 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00468939 |
| CTSE | cathepsin E | -0.00468276 |
| AOC1 | amine oxidase, copper containing 1 | -0.0046761 |
| OLFML3 | olfactomedin-like 3 | -0.00467398 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0046708 |
| HEATR1 | HEAT repeat containing 1 | -0.00465268 |
| EGR3 | early growth response 3 | -0.00464506 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00459634 |
| OPHN1 | oligophrenin 1 | -0.00457695 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00457108 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00455941 |
| SPRR2B | small proline-rich protein 2B | -0.00454783 |
| EMP2 | epithelial membrane protein 2 | -0.00453947 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00453466 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00452721 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.0045262 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00452587 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00449273 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00448396 |
| ITM2C | integral membrane protein 2C | -0.00448066 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00445072 |
| TCTN2 | tectonic family member 2 | -0.00444714 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00442955 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00442945 |
| BEX4 | brain expressed, X-linked 4 | -0.00439054 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00436982 |
| ANXA11 | annexin A11 | -0.00435934 |
| KLF6 | Kruppel-like factor 6 | -0.00435461 |
| ATF4 | activating transcription factor 4 | -0.00434946 |
| GOLT1B | golgi transport 1B | -0.00434886 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00433924 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00433395 |
| INHBA | inhibin, beta A | -0.00430941 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00429033 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00427933 |
| RBBP4 | retinoblastoma binding protein 4 | -0.00426723 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00426458 |
| FAM111A | family with sequence similarity 111, member A | -0.00426378 |
| MT1X | metallothionein 1X | -0.00426376 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0042615 |
| AKIRIN1 | akirin 1 | -0.00425452 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00425066 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0042468 |
| LGALSL | lectin, galactoside-binding-like | -0.0042394 |
| SH3BGR | SH3 domain binding glutamate-rich protein | -0.00423769 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00422471 |
| CIT | citron rho-interacting serine/threonine kinase | -0.0042227 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.0041829 |
| MECOM | MDS1 and EVI1 complex locus | -0.0041743 |
| IER3 | immediate early response 3 | -0.00417379 |
| CSTB | cystatin B (stefin B) | -0.00416969 |
| WLS | wntless Wnt ligand secretion mediator | -0.0041685 |
| S100A7 | S100 calcium binding protein A7 | -0.00416808 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.0041477 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00406125 |
| ABI2 | abl-interactor 2 | -0.00405217 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00404678 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00404176 |
| SPRR1A | small proline-rich protein 1A | -0.00403648 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0040134 |
| XBP1 | X-box binding protein 1 | -0.00400281 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.0039935 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00398665 |
| EMP1 | epithelial membrane protein 1 | -0.00396055 |
| S100A10 | S100 calcium binding protein A10 | -0.00395455 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00394569 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00394191 |
| DOK5 | docking protein 5 | -0.00393967 |
| MCL1 | myeloid cell leukemia 1 | -0.00393811 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00393525 |
| FAM107A | family with sequence similarity 107, member A | -0.00393151 |
| AK4 | adenylate kinase 4 | -0.00392699 |
| ATP10B | ATPase, class V, type 10B | -0.00388865 |
| STK24 | serine/threonine kinase 24 | -0.00387801 |
| CNN3 | calponin 3, acidic | -0.00387676 |
| RHOC | ras homolog family member C | -0.00387316 |
| GLO1 | glyoxalase I | -0.00386465 |
| OGA | O-GlcNAcase | -0.00386258 |
| AK2 | adenylate kinase 2 | -0.00384661 |
| USP46 | ubiquitin specific peptidase 46 | -0.00384654 |
| CGGBP1 | CGG triplet repeat binding protein 1 | -0.00384643 |
| GPI | glucose-6-phosphate isomerase | -0.00383178 |
| EXOC5 | exocyst complex component 5 | -0.00382838 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.0038128 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.00380974 |
| KRT1 | keratin 1, type II | -0.00380508 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.00380243 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00379135 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | -0.00378171 |
| REG1A | regenerating islet-derived 1 alpha | -0.00377684 |
| SNX11 | sorting nexin 11 | -0.0037743 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00377287 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0037627 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.0037537 |
| RNF144A | ring finger protein 144A | -0.00374849 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00373589 |
| PLP1 | proteolipid protein 1 | -0.00373171 |
| RGS4 | regulator of G-protein signaling 4 | -0.00372982 |
| RNASET2 | ribonuclease T2 | -0.00372982 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0037293 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.0037237 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00372226 |
| PGD | phosphogluconate dehydrogenase | -0.00372007 |
| SPRR1B | small proline-rich protein 1B | -0.00372006 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00371599 |
| SET | SET nuclear proto-oncogene | -0.00371307 |
| PER1 | period circadian clock 1 | -0.00369485 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0036902 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00368458 |
| METTL7A | methyltransferase like 7A | -0.00368394 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00367613 |
| AHNAK | AHNAK nucleoprotein | -0.00367431 |
| THY1 | Thy-1 cell surface antigen | -0.0036722 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00366715 |
| BAX | BCL2-associated X protein | -0.00365332 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00365257 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.00362618 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00362474 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00362368 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00361608 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00361497 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00361264 |
| RANBP9 | RAN binding protein 9 | -0.00360999 |
| SP110 | SP110 nuclear body protein | -0.00360328 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00360153 |
| TLR4 | toll-like receptor 4 | -0.00359758 |
| GSPT2 | G1 to S phase transition 2 | -0.00359335 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00359168 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.00358603 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00358397 |
| FMOD | fibromodulin | -0.00357754 |
| KLK5 | kallikrein-related peptidase 5 | -0.00357652 |
| SPRR3 | small proline-rich protein 3 | -0.00355881 |
| WASF2 | WAS protein family, member 2 | -0.00355852 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00355687 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00355588 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | -0.00355239 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00354994 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.00354471 |
| CEPT1 | choline/ethanolamine phosphotransferase 1 | -0.00352716 |
| MLF1 | myeloid leukemia factor 1 | -0.00351734 |
| GPM6B | glycoprotein M6B | -0.0035149 |
| LPIN1 | lipin 1 | -0.00350183 |
| CCK | cholecystokinin | -0.00350162 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00349625 |
| CTBS | chitobiase, di-N-acetyl- | -0.00349357 |
| PCBP1 | poly(rC) binding protein 1 | -0.00347575 |
| CDC42 | cell division cycle 42 | -0.0034704 |
| FBL | fibrillarin | -0.00346851 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00345217 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00344792 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00343677 |
| PXDN | peroxidasin | -0.00343661 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00343378 |
| TRIM22 | tripartite motif containing 22 | -0.00343055 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00341392 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00341134 |
| LTA4H | leukotriene A4 hydrolase | -0.00339247 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00339245 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.00339045 |
| MPZ | myelin protein zero | -0.00338688 |
| CRNN | cornulin | -0.00338432 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.00337851 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.00336333 |
| WAC | WW domain containing adaptor with coiled-coil | -0.00335996 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00335387 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | -0.00334439 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00334185 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00333625 |
| PRSS3 | protease, serine, 3 | -0.00333106 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00332237 |
| DSG1 | desmoglein 1 | -0.00332096 |
| FOXG1 | forkhead box G1 | -0.00332062 |
| IL1R2 | interleukin 1 receptor, type II | -0.00331842 |
| CLDND1 | claudin domain containing 1 | -0.00331275 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.00329976 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.00329134 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.0032893 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00328774 |
| DEFB4A | defensin, beta 4A | -0.00328618 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00328487 |
