PHLDA1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description pleckstrin homology-like domain, family A, member 1|This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 22822)
External Link https://ncbi.nlm.nih.gov/gene/22822
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Genes

499 genes differentially expressed following the PHLDA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SIRT3 sirtuin 3 0.0226547
RGCC regulator of cell cycle 0.0173306
XIC X chromosome inactivation center 0.0146718
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0137395
HSPA1A heat shock 70kDa protein 1A 0.013675
KRT5 keratin 5, type II 0.0121345
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0109942
INHBB inhibin, beta B 0.0105653
STC2 stanniocalcin 2 0.0104488
RB1 retinoblastoma 1 0.0102458
MET MET proto-oncogene, receptor tyrosine kinase 0.00972729
MAGEA3 melanoma antigen family A3 0.0096365
SMC1A structural maintenance of chromosomes 1A 0.00947979
PEG10 paternally expressed 10 0.00928334
SCGB2A1 secretoglobin, family 2A, member 1 0.00920235
ADM adrenomedullin 0.00916582
SCGB2A2 secretoglobin, family 2A, member 2 0.0089624
SCGB1D2 secretoglobin, family 1D, member 2 0.00887473
MAGEA12 melanoma antigen family A12 0.00881526
CHI3L2 chitinase 3-like 2 0.00869463
DLK1 delta-like 1 homolog (Drosophila) 0.00858025
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00852722
ZMYM2 zinc finger, MYM-type 2 0.00851188
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00851044
OXTR oxytocin receptor 0.00839112
COL2A1 collagen, type II, alpha 1 0.00836951
MYBPC1 myosin binding protein C, slow type 0.00834891
LRRC17 leucine rich repeat containing 17 0.00833446
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00821553
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00820962
PDGFC platelet derived growth factor C 0.00807066
PTN pleiotrophin 0.00802942
TSPAN5 tetraspanin 5 0.00799955
CCN2 cellular communication network factor 2 0.00786239
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00784917
ISG15 ISG15 ubiquitin-like modifier 0.00779529
AUTS2 autism susceptibility candidate 2 0.00777519
BGN biglycan 0.00768254
ADI1 acireductone dioxygenase 1 0.00761192
KRT14 keratin 14, type I 0.00739536
EGR1 early growth response 1 0.00735743
SERTAD2 SERTA domain containing 2 0.00733273
ARMCX2 armadillo repeat containing, X-linked 2 0.00722059
TRPS1 trichorhinophalangeal syndrome I 0.00721179
ANO1 anoctamin 1, calcium activated chloride channel 0.00719534
LEF1 lymphoid enhancer-binding factor 1 0.00716985
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00712027
LIMS1 LIM and senescent cell antigen-like domains 1 0.00709305
EFR3A EFR3 homolog A (S. cerevisiae) 0.00706475
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00705252
RHOB ras homolog family member B 0.00704404
ANGPT1 angiopoietin 1 0.00700699
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.00700089
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.0068791
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00686307
LEPROT leptin receptor overlapping transcript 0.00685741
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.0068231
FOXG1 forkhead box G1 0.00681618
ZNF331 zinc finger protein 331 0.00675712
ATAD2 ATPase family, AAA domain containing 2 0.00675265
HSPH1 heat shock 105kDa/110kDa protein 1 0.00675119
VWF von Willebrand factor 0.00675069
ARMCX3 armadillo repeat containing, X-linked 3 0.00672521
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00672157
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.0067199
CTR9 CTR9, Paf1/RNA polymerase II complex component 0.0066545
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00663058
FNDC3A fibronectin type III domain containing 3A 0.00662585
CIT citron rho-interacting serine/threonine kinase 0.00653203
PDHX pyruvate dehydrogenase complex, component X 0.00652868
KLF10 Kruppel-like factor 10 0.00652351
SPAG9 sperm associated antigen 9 0.00651177
CBX1 chromobox homolog 1 0.00651108
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00643102
TTN titin 0.00640958
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00638232
EFHD1 EF-hand domain family, member D1 0.00638008
RSF1 remodeling and spacing factor 1 0.00637404
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00637145
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00634321
GLUL glutamate-ammonia ligase 0.00633267
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.00632448
NCALD neurocalcin delta 0.00627743
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00622782
ANKRD28 ankyrin repeat domain 28 0.00620188
KDM5B lysine (K)-specific demethylase 5B 0.00611682
SPEN spen family transcriptional repressor 0.00611485
PLPP3 phospholipid phosphatase 3 0.006085
NPC1 Niemann-Pick disease, type C1 0.0060649
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.00606359
CXCL2 chemokine (C-X-C motif) ligand 2 0.00604477
AQP4 aquaporin 4 0.0060425
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00604037
KRT15 keratin 15, type I 0.00602387
ALG8 ALG8, alpha-1,3-glucosyltransferase 0.00601087
VWA8 von Willebrand factor A domain containing 8 0.0059892
MRTFB myocardin related transcription factor B 0.0059677
SPIN1 spindlin 1 0.00596607
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00596335
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00596128
GAB2 GRB2-associated binding protein 2 0.0059513
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00594847
LRRN3 leucine rich repeat neuronal 3 0.00594635
SEH1L SEH1-like (S. cerevisiae) 0.00594479
SH3BP4 SH3-domain binding protein 4 0.00592549
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00592072
IPO7 importin 7 0.00589238
MYO1B myosin IB 0.00589045
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00588932
HIST1H2BK histone cluster 1, H2bk 0.00586964
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.00586517
TMEM14A transmembrane protein 14A 0.00584179
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.00583944
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00582785
NIBAN1 niban apoptosis regulator 1 0.00582641
TSC22D1 TSC22 domain family, member 1 0.00576704
SACS sacsin molecular chaperone 0.00576046
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.00575776
HAS2 hyaluronan synthase 2 0.0057569
ZEB1 zinc finger E-box binding homeobox 1 0.00574619
RNMT RNA (guanine-7-) methyltransferase 0.00570047
CLEC2D C-type lectin domain family 2, member D 0.00567153
KLHL41 kelch-like family member 41 0.00566912
ITPKB inositol-trisphosphate 3-kinase B 0.00566867
APOLD1 apolipoprotein L domain containing 1 0.00566501
CRABP2 cellular retinoic acid binding protein 2 0.00565563
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.00562256
RALBP1 ralA binding protein 1 0.00561803
TAC1 tachykinin, precursor 1 0.00561801
ABAT 4-aminobutyrate aminotransferase 0.00558296
CLEC2B C-type lectin domain family 2, member B 0.00557595
HMOX1 heme oxygenase 1 0.00556201
TMEM131 transmembrane protein 131 0.005558
KLHL24 kelch-like family member 24 0.00555691
MAGEA1 melanoma antigen family A1 0.00554496
BDNF brain-derived neurotrophic factor 0.00551647
ERVMER34-1 endogenous retrovirus group MER34, member 1 0.00550754
MID1 midline 1 0.00549989
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.0054953
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.00548026
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.00547935
HMBOX1 homeobox containing 1 0.00547354
DOCK9 dedicator of cytokinesis 9 0.00546704
CEP170 centrosomal protein 170kDa 0.00546393
CDK17 cyclin-dependent kinase 17 0.00546348
MED13 mediator complex subunit 13 0.005463
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.00543379
TGFBI transforming growth factor, beta-induced, 68kDa 0.00542304
CHIC2 cysteine-rich hydrophobic domain 2 0.00542107
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.00541764
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00541043
SEPP1 selenoprotein P, plasma, 1 0.00540574
CPD carboxypeptidase D 0.00540252
OXA1L oxidase (cytochrome c) assembly 1-like 0.00536565
EFNB2 ephrin-B2 0.00536238
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00535768
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00533627
PRRC2C proline-rich coiled-coil 2C 0.00530276
TBL1X transducin (beta)-like 1X-linked 0.00529629
RHOBTB3 Rho-related BTB domain containing 3 0.00529413
FOLR1 folate receptor 1 (adult) 0.00526474
OLFML2B olfactomedin-like 2B 0.00524712
NEK2 NIMA-related kinase 2 0.00524217
AZIN1 antizyme inhibitor 1 0.00521895
CCNA2 cyclin A2 0.00519881
POPDC3 popeye domain containing 3 0.00519624
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00516915
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00515905
HCRTR1 hypocretin (orexin) receptor 1 0.00515507
ASXL1 additional sex combs like transcriptional regulator 1 0.00515319
FN1 fibronectin 1 0.00514424
DBP D site of albumin promoter (albumin D-box) binding protein 0.00514344
MED1 mediator complex subunit 1 0.0051287
NCOA3 nuclear receptor coactivator 3 0.00512517
EIF3H eukaryotic translation initiation factor 3, subunit H 0.00511928
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.0051124
DSP desmoplakin 0.00510976
GATA2 GATA binding protein 2 0.00510615
VEGFA vascular endothelial growth factor A 0.00510405
TFF3 trefoil factor 3 (intestinal) 0.00509024
SEC31A SEC31 homolog A (S. cerevisiae) 0.00508734
UBAP2 ubiquitin associated protein 2 0.00508045
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00507902
HOMER1 homer scaffolding protein 1 0.00507654
ABHD6 abhydrolase domain containing 6 0.00506677
ABI2 abl-interactor 2 0.00505965
RGS3 regulator of G-protein signaling 3 0.00505879
RRAGD Ras-related GTP binding D 0.00505641
KAT6B K(lysine) acetyltransferase 6B 0.00505343
CLCN4 chloride channel, voltage-sensitive 4 0.00505237
CGA glycoprotein hormones, alpha polypeptide 0.00505214
TNC tenascin C 0.00504984
ANGPT2 angiopoietin 2 0.00504972
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0050421
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00502313
KDM3A lysine (K)-specific demethylase 3A 0.00501926
KRT6A keratin 6A, type II 0.00501876
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00500751
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00500325
PER1 period circadian clock 1 0.00500308
PELI1 pellino E3 ubiquitin protein ligase 1 0.00498918
PSG5 pregnancy specific beta-1-glycoprotein 5 0.00498527
TBC1D4 TBC1 domain family, member 4 0.00498306
ATP7A ATPase, Cu++ transporting, alpha polypeptide 0.00498238
ZNF395 zinc finger protein 395 0.0049735
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00496988
NRXN2 neurexin 2 0.00496437
EGR3 early growth response 3 0.00495858
MRPS30 mitochondrial ribosomal protein S30 0.00495845
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 0.00495646
TMEM41B transmembrane protein 41B 0.00495303
TP63 tumor protein p63 0.00495271
ACVR1 activin A receptor, type I 0.00495176
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00494907
LYPLA1 lysophospholipase I 0.0049449
KRT23 keratin 23, type I 0.00494469
DAD1 defender against cell death 1 0.00493644
MARCHF7 membrane associated ring-CH-type finger 7 0.00493287
PRMT3 protein arginine methyltransferase 3 0.00493156
GLRX glutaredoxin (thioltransferase) 0.00493036
CXCL8 chemokine (C-X-C motif) ligand 8 0.0049299
ABHD2 abhydrolase domain containing 2 0.00492963
KDM6A lysine (K)-specific demethylase 6A 0.00492066
HIST1H2AC histone cluster 1, H2ac 0.00491545
ATXN7 ataxin 7 0.00491506
ATP10D ATPase, class V, type 10D 0.00491424
CCP110 centriolar coiled coil protein 110kDa 0.00491267
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.00491185
MED13L mediator complex subunit 13-like 0.00491134
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.00490279
MOB4 MOB family member 4, phocein 0.00490189
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00489565
PLS3 plastin 3 0.00488615
ALCAM activated leukocyte cell adhesion molecule 0.00488374
USP11 ubiquitin specific peptidase 11 0.00488248
SYNJ2 synaptojanin 2 0.00487659
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0048734
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00487131
DLX5 distal-less homeobox 5 0.00486849
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.0048615
MMP2 matrix metallopeptidase 2 0.004853
RYR1 ryanodine receptor 1 (skeletal) 0.00485118
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00484691
MACF1 microtubule-actin crosslinking factor 1 0.00484683
CREBBP CREB binding protein 0.00484178
ASCL1 achaete-scute family bHLH transcription factor 1 0.00484079
FGFR1 fibroblast growth factor receptor 1 0.00483754
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.00483243
TBC1D31 TBC1 domain family, member 31 0.00482922

decreased expression

Symbol Name Standardized Value
REG1A regenerating islet-derived 1 alpha -0.0170518
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.015617
LCN2 lipocalin 2 -0.0152497
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0145813
TSPAN8 tetraspanin 8 -0.0134159
OLFM4 olfactomedin 4 -0.0133613
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.0131934
S100A8 S100 calcium binding protein A8 -0.0130652
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.0127388
REG1B regenerating islet-derived 1 beta -0.0115563
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0113691
DCN decorin -0.0111702
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0111026
GPX2 glutathione peroxidase 2 -0.0110755
ANXA4 annexin A4 -0.0108548
C7 complement component 7 -0.0108419
ADAMDEC1 ADAM-like, decysin 1 -0.0104919
REG3A regenerating islet-derived 3 alpha -0.0101636
PLBD1 phospholipase B domain containing 1 -0.0101124
PLN phospholamban -0.010106
AGR2 anterior gradient 2 -0.00994427
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00982889
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00978865
IRF8 interferon regulatory factor 8 -0.00971072
PDZK1IP1 PDZK1 interacting protein 1 -0.00959041
CCR2 chemokine (C-C motif) receptor 2 -0.00958354
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00950353
TRAPPC3 trafficking protein particle complex 3 -0.00942154
GREM1 gremlin 1, DAN family BMP antagonist -0.00932852
WISP2 WNT1 inducible signaling pathway protein 2 -0.00927451
FZD5 frizzled class receptor 5 -0.00922466
CCL19 chemokine (C-C motif) ligand 19 -0.00921158
CCL5 chemokine (C-C motif) ligand 5 -0.0090875
TMC5 transmembrane channel-like 5 -0.00902659
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.0089064
CHRDL1 chordin-like 1 -0.00884607
C1R complement component 1, r subcomponent -0.00879116
KDM5D lysine (K)-specific demethylase 5D -0.00876595
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00875829
TLCD3A TLC domain containing 3A -0.00871053
FGL2 fibrinogen-like 2 -0.00867683
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00866127
DMBT1 deleted in malignant brain tumors 1 -0.00858417
TOX3 TOX high mobility group box family member 3 -0.00858032
PDGFRL platelet-derived growth factor receptor-like -0.00857871
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00855965
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00853791
LYZ lysozyme -0.0085219
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00850867
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00841174
CSTA cystatin A (stefin A) -0.00838205
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00836398
JCHAIN joining chain of multimeric IgA and IgM -0.00832764
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00830226
CFB complement factor B -0.00827977
RNH1 ribonuclease/angiogenin inhibitor 1 -0.00825005
GATA6 GATA binding protein 6 -0.00818023
CHP1 calcineurin-like EF-hand protein 1 -0.00816454
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.0080894
CYBB cytochrome b-245, beta polypeptide -0.0080513
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00803518
NVL nuclear VCP-like -0.00798391
CTSK cathepsin K -0.00797212
S100A9 S100 calcium binding protein A9 -0.00793572
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00792695
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00791426
SFRP4 secreted frizzled-related protein 4 -0.00789639
LEFTY1 left-right determination factor 1 -0.00787374
DHDDS dehydrodolichyl diphosphate synthase -0.00787107
MUC4 mucin 4, cell surface associated -0.00786829
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00782213
PNMA2 paraneoplastic Ma antigen 2 -0.00779137
PRKCB protein kinase C, beta -0.00776905
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00774885
AP1M2 adaptor-related protein complex 1, mu 2 subunit -0.00758284
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00756128
LUM lumican -0.00753636
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 -0.00750582
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00747828
TST thiosulfate sulfurtransferase (rhodanese) -0.00743616
TPD52 tumor protein D52 -0.00738628
MCOLN1 mucolipin 1 -0.00728498
SAMHD1 SAM domain and HD domain 1 -0.00727445
MTMR11 myotubularin related protein 11 -0.00724559
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00724247
KIAA0930 KIAA0930 -0.00723303
BTG2 BTG family, member 2 -0.007223
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -0.00721308
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00719551
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00715418
TMEM45A transmembrane protein 45A -0.00704517
PDE9A phosphodiesterase 9A -0.00699165
CFD complement factor D (adipsin) -0.00698732
PCGF2 polycomb group ring finger 2 -0.00697316
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00691312
SLC44A4 solute carrier family 44, member 4 -0.00685117
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00684591
NPY1R neuropeptide Y receptor Y1 -0.00680901
PTGES prostaglandin E synthase -0.00679386
EIF5A eukaryotic translation initiation factor 5A -0.00678625
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.00677858
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.00676868
CCL11 chemokine (C-C motif) ligand 11 -0.0067555
CHMP4A charged multivesicular body protein 4A -0.00672082
ASPN asporin -0.00670892
DES desmin -0.00669287
ENO2 enolase 2 (gamma, neuronal) -0.00668045
COL14A1 collagen, type XIV, alpha 1 -0.00666578
LINC00623 long intergenic non-protein coding RNA 623 -0.00666462
ACTG2 actin, gamma 2, smooth muscle, enteric -0.0066546
ADAT1 adenosine deaminase, tRNA-specific 1 -0.00664004
C8ORF4 chromosome 8 open reading frame 4 -0.00660973
TRIB2 tribbles pseudokinase 2 -0.00658804
OPTN optineurin -0.00654296
TGM2 transglutaminase 2 -0.00654261
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00654232
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.00650806
BLNK B-cell linker -0.00647171
VCAM1 vascular cell adhesion molecule 1 -0.00642957
CDC42 cell division cycle 42 -0.00641428
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.00640503
KRT19 keratin 19, type I -0.006405
MUC13 mucin 13, cell surface associated -0.00638456
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00635559
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00634828
ALOX5 arachidonate 5-lipoxygenase -0.00634589
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -0.00634253
PDLIM3 PDZ and LIM domain 3 -0.00633833
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00630494
PBLD phenazine biosynthesis-like protein domain containing -0.00630136
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00629706
SCG5 secretogranin V -0.00628233
INSM1 insulinoma-associated 1 -0.00627395
CTSS cathepsin S -0.00623928
CPVL carboxypeptidase, vitellogenic-like -0.00623788
TRIP6 thyroid hormone receptor interactor 6 -0.00622896
GPX3 glutathione peroxidase 3 -0.00621029
RNASE6 ribonuclease, RNase A family, k6 -0.00620288
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00618863
TFF1 trefoil factor 1 -0.00618362
SORBS1 sorbin and SH3 domain containing 1 -0.00616853
FCGBP Fc fragment of IgG binding protein -0.00615315
CLCA4 chloride channel accessory 4 -0.00614527
MLXIP MLX interacting protein -0.00614044
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.0061041
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00609344
THAP11 THAP domain containing 11 -0.0060919
FXYD3 FXYD domain containing ion transport regulator 3 -0.00608732
SATB2 SATB homeobox 2 -0.00606805
DGKZ diacylglycerol kinase, zeta -0.00605836
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.00604767
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.006031
L1TD1 LINE-1 type transposase domain containing 1 -0.00602075
EPCAM epithelial cell adhesion molecule -0.00601824
AK4 adenylate kinase 4 -0.00600298
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00595025
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00592988
CLCA1 chloride channel accessory 1 -0.00591731
SLAMF7 SLAM family member 7 -0.00591278
BIRC3 baculoviral IAP repeat containing 3 -0.00590436
C1S complement component 1, s subcomponent -0.0059019
TSPYL5 TSPY-like 5 -0.00590063
CADPS2 Ca++-dependent secretion activator 2 -0.00589868
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00589288
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00587149
EHF ets homologous factor -0.00587115
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -0.00584379
C3 complement component 3 -0.0058393
GZMK granzyme K (granzyme 3; tryptase II) -0.00583
TYRO3 TYRO3 protein tyrosine kinase -0.00581307
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00580505
DLG3 discs, large homolog 3 (Drosophila) -0.00577839
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00577022
MMP7 matrix metallopeptidase 7 -0.00576536
LST1 leukocyte specific transcript 1 -0.00575496
GAS1 growth arrest-specific 1 -0.00572488
CDC42SE1 CDC42 small effector 1 -0.00571636
S100A12 S100 calcium binding protein A12 -0.0057123
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00570164
TMEM176B transmembrane protein 176B -0.00568429
CA2 carbonic anhydrase II -0.0056685
ADAP1 ArfGAP with dual PH domains 1 -0.00566843
ABHD17A abhydrolase domain containing 17A -0.00566788
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.0056458
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00564343
NANOG Nanog homeobox -0.00563753
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00562517
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00561914
CAMP cathelicidin antimicrobial peptide -0.0056184
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00561791
LIN28A lin-28 homolog A (C. elegans) -0.00559449
QPCT glutaminyl-peptide cyclotransferase -0.00555787
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00555711
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00555218
C4ORF19 chromosome 4 open reading frame 19 -0.00554707
SPON1 spondin 1, extracellular matrix protein -0.0055362
S100P S100 calcium binding protein P -0.00553552
DPEP1 dipeptidase 1 (renal) -0.00550987
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.00550379
CCL20 chemokine (C-C motif) ligand 20 -0.00550373
CREBL2 cAMP responsive element binding protein-like 2 -0.00549861
MFAP5 microfibrillar associated protein 5 -0.00548574
NKG7 natural killer cell granule protein 7 -0.00548278
ARRB2 arrestin, beta 2 -0.00547834
RELN reelin -0.00546107
TMOD1 tropomodulin 1 -0.00543491
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00543356
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00543203
KRT20 keratin 20, type I -0.00540873
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00539501
TCEAL2 transcription elongation factor A (SII)-like 2 -0.00538612
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.00538299
TMEM106C transmembrane protein 106C -0.00538083
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00537607
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00536865
NFE2L3 nuclear factor, erythroid 2-like 3 -0.0053426
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -0.00534131
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00532756
G6PD glucose-6-phosphate dehydrogenase -0.00532475
LXN latexin -0.00532222
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -0.0053211
MT1F metallothionein 1F -0.00531246
RNPS1 RNA binding protein S1, serine-rich domain -0.00530814
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00530362
DEFB1 defensin, beta 1 -0.00529968
CALB1 calbindin 1, 28kDa -0.00529887
GCHFR GTP cyclohydrolase I feedback regulator -0.00529666
CRYAB crystallin, alpha B -0.00528856
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00526141
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00525515
ADGRG1 adhesion G protein-coupled receptor G1 -0.00524604
METTL7A methyltransferase like 7A -0.00523647
LY86 lymphocyte antigen 86 -0.0052227
AOX1 aldehyde oxidase 1 -0.00522103
WTAP Wilms tumor 1 associated protein -0.00521751
SUB1 SUB1 homolog (S. cerevisiae) -0.00521315
RTN1 reticulon 1 -0.00521268
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -0.00520862
TCF21 transcription factor 21 -0.00520519
IFT52 intraflagellar transport 52 -0.00518648
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -0.00514867
MAOA monoamine oxidase A -0.00513916
CRIP2 cysteine-rich protein 2 -0.00512249
MYRF myelin regulatory factor -0.00511756
CYBA cytochrome b-245, alpha polypeptide -0.00511354
WBP5 WW domain binding protein 5 -0.00509219
SF3B5 splicing factor 3b, subunit 5, 10kDa -0.00508985
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00508812
FAR2 fatty acyl CoA reductase 2 -0.00508616
TSPAN1 tetraspanin 1 -0.00508212