PHYHIP Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phytanoyl-CoA 2-hydroxylase interacting protein| (NCBI Entrez Gene Database, 9796)
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Genes

290 genes differentially expressed following the PHYHIP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SDS serine dehydratase 2.67398
LEF1 lymphoid enhancer-binding factor 1 2.67398
IL17C interleukin 17C 2.67398
TP63 tumor protein p63 2.67398
MUC6 mucin 6, oligomeric mucus/gel-forming 2.67398
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.67398
BAHCC1 BAH domain and coiled-coil containing 1 2.67398
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.67398
PGLYRP1 peptidoglycan recognition protein 1 2.67398
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 2.67398
APOB apolipoprotein B 2.67398
HRG histidine-rich glycoprotein 2.67398
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.67398
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.67398
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.67398
CCN6 cellular communication network factor 6 2.67398
WNT3A wingless-type MMTV integration site family, member 3A 2.67398
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 2.67398
PCDHB8 protocadherin beta 8 2.67354
CA7 carbonic anhydrase VII 2.67354
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.67354
SPINK4 serine peptidase inhibitor, Kazal type 4 2.67354
VWA5B2 von Willebrand factor A domain containing 5B2 2.67354
WDR87 WD repeat domain 87 2.67354
USP26 ubiquitin specific peptidase 26 2.67354
USP24 ubiquitin specific peptidase 24 2.67354
FOLR1 folate receptor 1 (adult) 2.67354
GPR75 G protein-coupled receptor 75 2.67354
GPR4 G protein-coupled receptor 4 2.67354
APLN apelin 2.67354
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 2.67354
ATOH8 atonal homolog 8 (Drosophila) 2.67354
ATOH7 atonal homolog 7 (Drosophila) 2.67354
MPL MPL proto-oncogene, thrombopoietin receptor 2.67354
GALR3 galanin receptor 3 2.67354
MAGIX MAGI family member, X-linked 2.67354
STK31 serine/threonine kinase 31 2.67354
EPHB3 EPH receptor B3 2.67354
METTL21C methyltransferase like 21C 2.67354
TTLL2 tubulin tyrosine ligase-like family member 2 2.67354
GMFG glia maturation factor, gamma 2.67354
TDRD9 tudor domain containing 9 2.67354
LRRC56 leucine rich repeat containing 56 2.67354
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.67354
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.67354
ADAD2 adenosine deaminase domain containing 2 2.67354
ARSF arylsulfatase F 2.67354
RFPL2 ret finger protein-like 2 2.67354
ANKRD34A ankyrin repeat domain 34A 2.67354
HAS1 hyaluronan synthase 1 2.67354
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 2.67354
KLHL35 kelch-like family member 35 2.67354
C1ORF202 chromosome 1 open reading frame 202 2.67354
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.67354
RHCG Rh family, C glycoprotein 2.67354
GIPR gastric inhibitory polypeptide receptor 2.67354
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.67354
GRAP GRB2-related adaptor protein 2.67354
GPR37L1 G protein-coupled receptor 37 like 1 2.67354
LY6K lymphocyte antigen 6 complex, locus K 2.67354
CCDC42 coiled-coil domain containing 42 2.67354
YPEL4 yippee-like 4 (Drosophila) 2.67354
RAG2 recombination activating gene 2 2.67354
SMIM43 small integral membrane protein 43 2.67354
ACP7 acid phosphatase 7, tartrate resistant (putative) 2.67354
TAMALIN trafficking regulator and scaffold protein tamalin 2.67354
VEGFD vascular endothelial growth factor D 2.67354
FAM237B family with sequence similarity 237 member B 2.67354
KYAT1 kynurenine aminotransferase 1 2.67354
MISP3 MISP family member 3 2.67354
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 2.67354
ZC3H11C zinc finger CCCH-type containing 11C 2.67354
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 2.67354
PMP22 peripheral myelin protein 22 2.67354
ZSWIM3 zinc finger, SWIM-type containing 3 2.67354
THPO thrombopoietin 2.67354
ITK IL2-inducible T-cell kinase 2.67354
CLDN5 claudin 5 2.67354
CCDC17 coiled-coil domain containing 17 2.67354
PTPRQ protein tyrosine phosphatase, receptor type, Q 2.67354
ACOT1 acyl-CoA thioesterase 1 2.67354
OR2A1 olfactory receptor, family 2, subfamily A, member 1 2.67354
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 2.67354
CXCL14 chemokine (C-X-C motif) ligand 14 2.67354
LGSN lengsin, lens protein with glutamine synthetase domain 2.67354
PLEK2 pleckstrin 2 2.67354
TAS1R1 taste receptor, type 1, member 1 2.67354
STARD6 StAR-related lipid transfer (START) domain containing 6 2.67354
VCX3A variable charge, X-linked 3A 2.67354
OVOL1 ovo-like zinc finger 1 2.67354
GJD2 gap junction protein, delta 2, 36kDa 2.67354
NPNT nephronectin 2.67354
KLF17 Kruppel-like factor 17 2.67354
TBC1D21 TBC1 domain family, member 21 2.67354
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.67354
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.67354
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.67354
PCDH17 protocadherin 17 2.67354
CCDC73 coiled-coil domain containing 73 2.67354
FAM135B family with sequence similarity 135, member B 2.67354
EPHA10 EPH receptor A10 2.67354
CALR3 calreticulin 3 2.67354
KLF1 Kruppel-like factor 1 (erythroid) 2.67354
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.67354
AQP5 aquaporin 5 2.67354
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 2.67354
SPTBN5 spectrin, beta, non-erythrocytic 5 2.67354
MAGEA2B melanoma antigen family A2B 2.67354
KCNK2 potassium channel, two pore domain subfamily K, member 2 2.67354
SOWAHD sosondowah ankyrin repeat domain family member D 2.67354
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 2.67354
CST1 cystatin SN 2.67354
TESPA1 thymocyte expressed, positive selection associated 1 2.67354
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.67354
CRYBA1 crystallin, beta A1 2.67354
GPR146 G protein-coupled receptor 146 2.67354
PCDHAC1 protocadherin alpha subfamily C, 1 2.67354
GPRC6A G protein-coupled receptor, class C, group 6, member A 2.67354
PCDH20 protocadherin 20 2.67354
LRRN4 leucine rich repeat neuronal 4 2.67354
TTC22 tetratricopeptide repeat domain 22 2.67354
C22ORF31 chromosome 22 open reading frame 31 2.67354
ZPBP zona pellucida binding protein 2.67354
C1ORF105 chromosome 1 open reading frame 105 2.67354
FLRT3 fibronectin leucine rich transmembrane protein 3 2.67354
PSG1 pregnancy specific beta-1-glycoprotein 1 2.67354
ZGLP1 zinc finger, GATA-like protein 1 2.67354
LSMEM1 leucine-rich single-pass membrane protein 1 2.67354
WNK3 WNK lysine deficient protein kinase 3 2.67354
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.67354
INSM1 insulinoma-associated 1 2.67354
GOLGA8R golgin A8 family, member R 2.67354
ATP10B ATPase, class V, type 10B 2.67354
HIGD2B HIG1 hypoxia inducible domain family, member 2B 2.67354
GJC2 gap junction protein, gamma 2, 47kDa 2.67354
SYTL4 synaptotagmin-like 4 2.67354
RDH16 retinol dehydrogenase 16 (all-trans) 2.67354
LRRC38 leucine rich repeat containing 38 2.67354
LY6G5C lymphocyte antigen 6 complex, locus G5C 2.67354
ALLC allantoicase 2.67354
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 2.67354
GHRH growth hormone releasing hormone 2.67354
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.67354
ANGPTL3 angiopoietin-like 3 2.67354
ANGPTL5 angiopoietin-like 5 2.67354
SDSL serine dehydratase-like 2.67354
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 2.67354
ICAM5 intercellular adhesion molecule 5, telencephalin 2.67354
INPP5J inositol polyphosphate-5-phosphatase J 2.67354
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.67354
CD38 CD38 molecule 2.67354
UTS2B urotensin 2B 2.67354
ALOX5AP arachidonate 5-lipoxygenase-activating protein 2.67354
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.67354
MMP12 matrix metallopeptidase 12 2.67354
LPAR5 lysophosphatidic acid receptor 5 2.67354
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.67354
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 2.67354
CD36 CD36 molecule (thrombospondin receptor) 2.67354
APOL4 apolipoprotein L, 4 2.67354
FGF16 fibroblast growth factor 16 2.67354
R3HDML R3H domain containing-like 2.67354
CERCAM cerebral endothelial cell adhesion molecule 2.67354
ACSM6 acyl-CoA synthetase medium-chain family member 6 2.67299
PI15 peptidase inhibitor 15 2.64538
CLDN19 claudin 19 2.61561
H2AC12 H2A clustered histone 12 2.56284
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 2.52061
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.47458
TP53TG5 TP53 target 5 2.47458
C4ORF50 chromosome 4 open reading frame 50 2.47458
PPIB peptidylprolyl isomerase B (cyclophilin B) 2.474
CEP162 centrosomal protein 162kDa 2.437
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 2.42718
SBSPON somatomedin B and thrombospondin, type 1 domain containing 2.42718
FAM131A family with sequence similarity 131, member A 2.37241
SGK3 serum/glucocorticoid regulated kinase family, member 3 2.30857
RBM23 RNA binding motif protein 23 2.29817
HTT huntingtin 2.29178
FAM204A family with sequence similarity 204, member A 2.28943
MRPL28 mitochondrial ribosomal protein L28 2.24719
LITAF lipopolysaccharide-induced TNF factor 2.22992
TRAF4 TNF receptor-associated factor 4 2.20676
GPC5 glypican 5 2.19645
MZT1 mitotic spindle organizing protein 1 2.19497
SEC16A SEC16 homolog A (S. cerevisiae) 2.19301
ANKRD40 ankyrin repeat domain 40 2.18897
ARHGAP24 Rho GTPase activating protein 24 2.18897
CSF1 colony stimulating factor 1 (macrophage) 2.18658
H2BC1 H2B clustered histone 1 2.18658
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.16307
ZNF394 zinc finger protein 394 2.13631
LMTK2 lemur tyrosine kinase 2 2.13631
MAP1S microtubule-associated protein 1S 2.13631
DCTD dCMP deaminase 2.1069
RECQL RecQ helicase-like 2.1057
GIGYF2 GRB10 interacting GYF protein 2 2.07828
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria 2.06918
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 2.06918
FAAH2 fatty acid amide hydrolase 2 2.06871
CDR2 cerebellar degeneration-related protein 2, 62kDa 2.05207
PRDX2 peroxiredoxin 2 2.03407

decreased expression

Symbol Name Standardized Value
PRIMA1 proline rich membrane anchor 1 -2.67398
IFI16 interferon, gamma-inducible protein 16 -2.67398
CCDC160 coiled-coil domain containing 160 -2.67398
ZNF837 zinc finger protein 837 -2.67398
CHMP4A charged multivesicular body protein 4A -2.67398
CYTIP cytohesin 1 interacting protein -2.67398
STBD1 starch binding domain 1 -2.67398
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.67398
IDUA iduronidase, alpha-L- -2.67354
ADAT3 adenosine deaminase, tRNA-specific 3 -2.67354
DTNB dystrobrevin, beta -2.67354
SPX spexin hormone -2.67354
MIXL1 Mix paired-like homeobox -2.67354
PKD1L1 polycystic kidney disease 1 like 1 -2.67354
TPH2 tryptophan hydroxylase 2 -2.67354
PSD4 pleckstrin and Sec7 domain containing 4 -2.67354
CHP2 calcineurin-like EF-hand protein 2 -2.67354
SMG6 SMG6 nonsense mediated mRNA decay factor -2.67354
RGPD1 RANBP2-like and GRIP domain containing 1 -2.67354
CEP19 centrosomal protein 19kDa -2.67354
ZNF71 zinc finger protein 71 -2.67354
SRPK2 SRSF protein kinase 2 -2.67354
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -2.67354
PARVG parvin, gamma -2.67354
POU2F3 POU class 2 homeobox 3 -2.67354
ZFP3 ZFP3 zinc finger protein -2.67354
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -2.67354
ACP2 acid phosphatase 2, lysosomal -2.67354
PCDHB15 protocadherin beta 15 -2.67354
TAS2R30 taste receptor, type 2, member 30 -2.67354
TMEM144 transmembrane protein 144 -2.67354
LURAP1L leucine rich adaptor protein 1-like -2.67354
HES4 hes family bHLH transcription factor 4 -2.67354
MID2 midline 2 -2.67354
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 -2.67354
SFN stratifin -2.67354
GDPGP1 GDP-D-glucose phosphorylase 1 -2.67354
FERMT3 fermitin family member 3 -2.67354
ZNF750 zinc finger protein 750 -2.67354
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 -2.67354
ZYG11B zyg-11 family member B, cell cycle regulator -2.67354
C6ORF136 chromosome 6 open reading frame 136 -2.67354
TTC19 tetratricopeptide repeat domain 19 -2.67354
ZCCHC18 zinc finger, CCHC domain containing 18 -2.67354
TUBA8 tubulin, alpha 8 -2.67354
RNF112 ring finger protein 112 -2.67354
SHOX short stature homeobox -2.67354
LAYN layilin -2.67354
NICN1 nicolin 1 -2.67354
COL28A1 collagen, type XXVIII, alpha 1 -2.67354
SEZ6L seizure related 6 homolog (mouse)-like -2.67354
LIF leukemia inhibitory factor -2.67354
SMKR1 small lysine-rich protein 1 -2.67354
SCARF1 scavenger receptor class F, member 1 -2.67354
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.67039
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -2.47458
PDLIM4 PDZ and LIM domain 4 -2.474
MROH8 maestro heat-like repeat family member 8 -2.474
ONECUT2 one cut homeobox 2 -2.474
PNMA2 paraneoplastic Ma antigen 2 -2.32699
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 -2.3059
METTL9 methyltransferase like 9 -2.30304
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 -2.29817
NTHL1 nth endonuclease III-like 1 (E. coli) -2.29662
LUC7L LUC7-like (S. cerevisiae) -2.24398
SCRN3 secernin 3 -2.23542
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 -2.23542
UFL1 UFM1-specific ligase 1 -2.23542
SMIM10 small integral membrane protein 10 -2.23542
ALOX12 arachidonate 12-lipoxygenase -2.23542
TNPO3 transportin 3 -2.2009
ADSS1 adenylosuccinate synthase 1 -2.19497
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 -2.17254
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.16955
STAT5B signal transducer and activator of transcription 5B -2.1489
ODAD3 outer dynein arm docking complex subunit 3 -2.14206
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.14206
MARCHF11 membrane associated ring-CH-type finger 11 -2.12183
CCDC22 coiled-coil domain containing 22 -2.12183
CCDC112 coiled-coil domain containing 112 -2.11531
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -2.10907
ST7L suppression of tumorigenicity 7 like -2.1069
SCO2 SCO2 cytochrome c oxidase assembly protein -2.10152
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 -2.09433
GON7 GON7 subunit of KEOPS complex -2.09245
SECISBP2 SECIS binding protein 2 -2.08533
L3MBTL4 l(3)mbt-like 4 (Drosophila) -2.07828
APOE apolipoprotein E -2.00316