| Dataset | Pathway Commons Protein-Protein Interactions |
| Category | physical interactions |
| Type | interacting protein |
| Description | peptidase inhibitor 3, skin-derived|This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014] (NCBI Entrez Gene Database, 5266) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/5266 |
| Similar Terms | |
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5 interacting proteins for PI3 from the Pathway Commons Protein-Protein Interactions dataset.
