PI4KA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description phosphatidylinositol 4-kinase, catalytic, alpha|This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014] (NCBI Entrez Gene Database, 5297)
External Link https://ncbi.nlm.nih.gov/gene/5297
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Genes

499 genes differentially expressed following the PI4KA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.0137485
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0113716
POSTN periostin, osteoblast specific factor 0.0109801
RXYLT1 ribitol xylosyltransferase 1 0.0104217
S100P S100 calcium binding protein P 0.0103378
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00992046
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00985919
SPARCL1 SPARC-like 1 (hevin) 0.00962322
PUF60 poly-U binding splicing factor 60KDa 0.00946296
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00933324
DHDDS dehydrodolichyl diphosphate synthase 0.00931963
ITGB1BP1 integrin beta 1 binding protein 1 0.00899471
NEBL nebulette 0.00896988
GMDS GDP-mannose 4,6-dehydratase 0.00891012
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00877828
NRN1 neuritin 1 0.00846927
TESC tescalcin 0.00828701
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00826598
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00824756
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00812881
TSPAN8 tetraspanin 8 0.00807015
ICAM2 intercellular adhesion molecule 2 0.00801563
TM4SF1 transmembrane 4 L six family member 1 0.00794805
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00790178
PLN phospholamban 0.00789747
ZMYM2 zinc finger, MYM-type 2 0.0078874
ESD esterase D 0.00781963
MRPL57 mitochondrial ribosomal protein L57 0.00779263
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00762537
TPM4 tropomyosin 4 0.00761817
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00731159
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00730451
MMP12 matrix metallopeptidase 12 0.00727439
TMEM100 transmembrane protein 100 0.00721465
LGALS13 lectin, galactoside-binding, soluble, 13 0.00719672
CEMIP cell migration inducing protein, hyaluronan binding 0.00718985
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00718849
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00712025
CST1 cystatin SN 0.00698227
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00697331
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00695364
IFITM1 interferon induced transmembrane protein 1 0.00692715
GTF3A general transcription factor IIIA 0.00691767
LXN latexin 0.00684314
PTK2 protein tyrosine kinase 2 0.00681899
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00680843
PDLIM1 PDZ and LIM domain 1 0.00678316
MGP matrix Gla protein 0.00678158
C6ORF48 chromosome 6 open reading frame 48 0.00673208
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00672348
CXCL5 chemokine (C-X-C motif) ligand 5 0.00662294
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00658394
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00653955
RNPS1 RNA binding protein S1, serine-rich domain 0.00653092
C3ORF14 chromosome 3 open reading frame 14 0.00651826
CXCL8 chemokine (C-X-C motif) ligand 8 0.00648932
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00647142
ISG20 interferon stimulated exonuclease gene 20kDa 0.00645942
PWP1 PWP1 homolog (S. cerevisiae) 0.00645599
WDR61 WD repeat domain 61 0.00641156
MRPS33 mitochondrial ribosomal protein S33 0.00633408
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.00627388
DMAC2L distal membrane arm assembly component 2 like 0.00626505
UGP2 UDP-glucose pyrophosphorylase 2 0.00626136
WASHC3 WASH complex subunit 3 0.00623092
MRPS16 mitochondrial ribosomal protein S16 0.00620332
DUOX2 dual oxidase 2 0.00617246
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0061506
FABP7 fatty acid binding protein 7, brain 0.00614371
NUP37 nucleoporin 37kDa 0.00613421
DYNLT3 dynein, light chain, Tctex-type 3 0.00612971
COX5A cytochrome c oxidase subunit Va 0.00609029
NNMT nicotinamide N-methyltransferase 0.00608473
CHRDL1 chordin-like 1 0.00605596
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.00605336
CD34 CD34 molecule 0.00599151
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00598599
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00597534
NPY1R neuropeptide Y receptor Y1 0.00597262
RAB25 RAB25, member RAS oncogene family 0.0059561
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00595116
KIAA0226L KIAA0226-like 0.00593919
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.00592152
HOPX HOP homeobox 0.00591689
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00587313
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00586836
PCCB propionyl CoA carboxylase, beta polypeptide 0.00583426
RFC2 replication factor C (activator 1) 2, 40kDa 0.0058
ANXA3 annexin A3 0.00578798
FASTKD5 FAST kinase domains 5 0.00576167
IFRD2 interferon-related developmental regulator 2 0.00575336
C8ORF4 chromosome 8 open reading frame 4 0.0057531
VWF von Willebrand factor 0.00574985
TMC5 transmembrane channel-like 5 0.00567122
BAMBI BMP and activin membrane-bound inhibitor 0.00565313
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 0.00564165
LIPG lipase, endothelial 0.0056345
GPX3 glutathione peroxidase 3 0.00561864
ICA1 islet cell autoantigen 1, 69kDa 0.00561632
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00561571
CNTN1 contactin 1 0.00553354
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00553154
MCAM melanoma cell adhesion molecule 0.00553083
TFF1 trefoil factor 1 0.00552413
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00550888
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.00549656
MCUB mitochondrial calcium uniporter dominant negative subunit beta 0.00548973
PLIN1 perilipin 1 0.00547217
TJP2 tight junction protein 2 0.00545075
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.0054488
INHBA inhibin, beta A 0.00543193
ARHGAP15 Rho GTPase activating protein 15 0.0054141
MREG melanoregulin 0.00540536
AGR2 anterior gradient 2 0.0054024
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.0053815
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00538141
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00536941
ADGRF5 adhesion G protein-coupled receptor F5 0.00535537
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00535457
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00535199
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00535102
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00535013
IL18 interleukin 18 0.00533026
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00532278
CXCL3 chemokine (C-X-C motif) ligand 3 0.00531987
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00530822
RWDD1 RWD domain containing 1 0.00529884
CYC1 cytochrome c-1 0.00528527
TSPAN13 tetraspanin 13 0.00528248
CLDN3 claudin 3 0.00527912
GPN1 GPN-loop GTPase 1 0.00527867
ZNF185 zinc finger protein 185 (LIM domain) 0.005272
RFK riboflavin kinase 0.0052711
EAF2 ELL associated factor 2 0.00525852
PER2 period circadian clock 2 0.00525407
EIF3E eukaryotic translation initiation factor 3, subunit E 0.00525394
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00524799
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00524601
POF1B premature ovarian failure, 1B 0.00523696
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00522962
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00521872
MYH11 myosin, heavy chain 11, smooth muscle 0.00521207
FZD6 frizzled class receptor 6 0.00521028
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase 0.00520791
RFC3 replication factor C (activator 1) 3, 38kDa 0.0051937
SPINK4 serine peptidase inhibitor, Kazal type 4 0.0051876
LGALSL lectin, galactoside-binding-like 0.00517129
ZFAND1 zinc finger, AN1-type domain 1 0.00516014
METTL5 methyltransferase like 5 0.00514495
MAP7 microtubule-associated protein 7 0.00512525
SRPX2 sushi-repeat containing protein, X-linked 2 0.00508018
BSPRY B-box and SPRY domain containing 0.00507641
TMED3 transmembrane emp24 protein transport domain containing 3 0.00507189
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) 0.00505929
SYNGR2 synaptogyrin 2 0.00505688
GMFG glia maturation factor, gamma 0.0050489
FLNB filamin B, beta 0.00504852
CCND2 cyclin D2 0.00503974
RIOX2 ribosomal oxygenase 2 0.00503007
CIAO3 cytosolic iron-sulfur assembly component 3 0.00502689
COCH cochlin 0.00502559
CXCL14 chemokine (C-X-C motif) ligand 14 0.00501563
MIPEP mitochondrial intermediate peptidase 0.00500881
PHF11 PHD finger protein 11 0.0050066
MALL mal, T-cell differentiation protein-like 0.00500053
AHCY adenosylhomocysteinase 0.00499565
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.00498703
SCEL sciellin 0.00497914
DARS1 aspartyl-tRNA synthetase 1 0.00497174
PRPF4 pre-mRNA processing factor 4 0.00495823
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.00495483
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00495268
C9ORF91 chromosome 9 open reading frame 91 0.00493313
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00492261
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.00490661
DRG1 developmentally regulated GTP binding protein 1 0.00490392
ATP5MG ATP synthase membrane subunit g 0.00488756
BCAS3 breast carcinoma amplified sequence 3 0.00488452
AK4 adenylate kinase 4 0.00487183
TXNDC9 thioredoxin domain containing 9 0.00486792
TSPYL5 TSPY-like 5 0.00486291
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00485036
CAB39 calcium binding protein 39 0.0048489
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00484755
RPS14P3 ribosomal protein S14 pseudogene 3 0.00483462
TPD52 tumor protein D52 0.00482956
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.00481691
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00481558
ATP5F1C ATP synthase F1 subunit gamma 0.00481296
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00480461
C9ORF16 chromosome 9 open reading frame 16 0.00480143
SIRT5 sirtuin 5 0.00479175
IL33 interleukin 33 0.00479122
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.00478934
TAGLN transgelin 0.00477799
COMP cartilage oligomeric matrix protein 0.00475704
HAUS4 HAUS augmin-like complex, subunit 4 0.00475118
RBM47 RNA binding motif protein 47 0.00474529
VAMP8 vesicle-associated membrane protein 8 0.00474452
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00472741
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00472545
FPR1 formyl peptide receptor 1 0.00469529
TIMP4 TIMP metallopeptidase inhibitor 4 0.00469149
VWA8 von Willebrand factor A domain containing 8 0.00468965
DPH5 diphthamide biosynthesis 5 0.00468959
ERP29 endoplasmic reticulum protein 29 0.00468873
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00468138
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00468106
DDIT4 DNA-damage-inducible transcript 4 0.00467007
MYO1C myosin IC 0.00466117
FAM107A family with sequence similarity 107, member A 0.0046542
EIF5 eukaryotic translation initiation factor 5 0.00465356
CCL8 chemokine (C-C motif) ligand 8 0.0046386
RNF43 ring finger protein 43 0.00462274
PSPC1 paraspeckle component 1 0.00461434
PMEPA1 prostate transmembrane protein, androgen induced 1 0.00460887
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00460853
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00459633
VSIG4 V-set and immunoglobulin domain containing 4 0.00459608
TRIM16 tripartite motif containing 16 0.00457983
MRPL19 mitochondrial ribosomal protein L19 0.00457538
SMYD3 SET and MYND domain containing 3 0.00457437
NMB neuromedin B 0.00456852
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1 0.00456029
GIMAP6 GTPase, IMAP family member 6 0.00455951
FCGBP Fc fragment of IgG binding protein 0.00455647
ATP10B ATPase, class V, type 10B 0.00454687
UGCG UDP-glucose ceramide glucosyltransferase 0.00454574
SUCLG1 succinate-CoA ligase, alpha subunit 0.00453664
TTC27 tetratricopeptide repeat domain 27 0.00451362
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00451231
ATRAID all-trans retinoic acid-induced differentiation factor 0.00449715
EPS8 epidermal growth factor receptor pathway substrate 8 0.00448858
PLPBP pyridoxal phosphate binding protein 0.00447817
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00447771
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00447672
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00447293
MORC4 MORC family CW-type zinc finger 4 0.00445099
HLA-DMB major histocompatibility complex, class II, DM beta 0.00445029
ARL1 ADP-ribosylation factor-like 1 0.00444852
NPR3 natriuretic peptide receptor 3 0.00444685
RPP40 ribonuclease P/MRP 40kDa subunit 0.00444619
GIMAP5 GTPase, IMAP family member 5 0.00444538
MDH1 malate dehydrogenase 1, NAD (soluble) 0.00444435
CYTL1 cytokine-like 1 0.00444301
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.00443842
CD48 CD48 molecule 0.0044327
HIST3H2A histone cluster 3, H2a 0.0044307
NEK3 NIMA-related kinase 3 0.0044247
CD1E CD1e molecule 0.00442233

decreased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 -0.0118228
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.010894
MAGEA3 melanoma antigen family A3 -0.0106947
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00988623
CA2 carbonic anhydrase II -0.00985606
CBS cystathionine-beta-synthase -0.00978338
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00961257
MFSD10 major facilitator superfamily domain containing 10 -0.00948034
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00944946
CRABP2 cellular retinoic acid binding protein 2 -0.00919668
TMEM45A transmembrane protein 45A -0.00898423
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00888909
ANPEP alanyl (membrane) aminopeptidase -0.00838532
PCOLCE procollagen C-endopeptidase enhancer -0.00836658
MEIS2 Meis homeobox 2 -0.00829053
TWIST1 twist family bHLH transcription factor 1 -0.00825404
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00817102
CPB1 carboxypeptidase B1 (tissue) -0.00799509
GSTA1 glutathione S-transferase alpha 1 -0.00797039
RAI14 retinoic acid induced 14 -0.00794666
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00787252
WLS wntless Wnt ligand secretion mediator -0.00771422
BEX1 brain expressed, X-linked 1 -0.00769317
ACADVL acyl-CoA dehydrogenase, very long chain -0.007605
SLC25A46 solute carrier family 25, member 46 -0.00751623
PDZRN3 PDZ domain containing ring finger 3 -0.00746237
PBX3 pre-B-cell leukemia homeobox 3 -0.00737514
GOLM1 golgi membrane protein 1 -0.00736989
CTSA cathepsin A -0.00731206
IL7R interleukin 7 receptor -0.00721233
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00720642
ZNF395 zinc finger protein 395 -0.00719509
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00717615
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -0.0071649
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 -0.00715932
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00698057
LTF lactotransferrin -0.00687898
COL6A1 collagen, type VI, alpha 1 -0.0067809
GOLGA8A golgin A8 family, member A -0.00676392
TMSB15A thymosin beta 15a -0.00672668
VCAM1 vascular cell adhesion molecule 1 -0.00667047
STIP1 stress-induced phosphoprotein 1 -0.00664411
ADGRA3 adhesion G protein-coupled receptor A3 -0.00653683
XPO7 exportin 7 -0.0065194
ORM1 orosomucoid 1 -0.0064823
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00645021
WT1 Wilms tumor 1 -0.0064364
SDC4 syndecan 4 -0.00642623
BCL6 B-cell CLL/lymphoma 6 -0.00641663
RRBP1 ribosome binding protein 1 -0.00636755
MMP2 matrix metallopeptidase 2 -0.00634769
TNS3 tensin 3 -0.00633416
CD63 CD63 molecule -0.00628511
MEIS1 Meis homeobox 1 -0.00628304
FLNA filamin A, alpha -0.00622508
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00621346
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3 -0.00620113
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00617021
MXI1 MAX interactor 1, dimerization protein -0.00614425
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00613321
CTBP2 C-terminal binding protein 2 -0.00611796
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00610892
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00606677
COL4A5 collagen, type IV, alpha 5 -0.00605404
PBX1 pre-B-cell leukemia homeobox 1 -0.00603934
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.00603581
IVD isovaleryl-CoA dehydrogenase -0.00602505
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00599368
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.00598957
S100A6 S100 calcium binding protein A6 -0.00598435
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00597647
BTG3 BTG family, member 3 -0.00596369
RHOBTB3 Rho-related BTB domain containing 3 -0.0059635
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00594609
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00593556
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00588671
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -0.00587373
FZD2 frizzled class receptor 2 -0.00582246
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00580758
FBN2 fibrillin 2 -0.00580113
S100A4 S100 calcium binding protein A4 -0.00579675
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00579396
CPOX coproporphyrinogen oxidase -0.00578914
LRP12 low density lipoprotein receptor-related protein 12 -0.00577841
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00576371
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00575782
CEP170 centrosomal protein 170kDa -0.00575641
XCL1 chemokine (C motif) ligand 1 -0.00574758
GPNMB glycoprotein (transmembrane) nmb -0.00574724
TTC3 tetratricopeptide repeat domain 3 -0.00572403
LYST lysosomal trafficking regulator -0.00571454
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta -0.00570884
DSP desmoplakin -0.00568149
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00567684
AZU1 azurocidin 1 -0.0056609
FGFR3 fibroblast growth factor receptor 3 -0.00565078
SEC24C SEC24 family member C -0.00562543
ANKRD11 ankyrin repeat domain 11 -0.00562148
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.00560232
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00560146
PDGFC platelet derived growth factor C -0.00559637
NUSAP1 nucleolar and spindle associated protein 1 -0.00558431
PRNP prion protein -0.00557888
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00556715
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00554915
ACLY ATP citrate lyase -0.0055378
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like -0.00553146
ZEB2 zinc finger E-box binding homeobox 2 -0.00551257
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00550008
DEFA4 defensin, alpha 4, corticostatin -0.00549269
RNPEP arginyl aminopeptidase (aminopeptidase B) -0.0054882
SCGB2A2 secretoglobin, family 2A, member 2 -0.00548521
CCN3 cellular communication network factor 3 -0.00544983
SLC38A1 solute carrier family 38, member 1 -0.00544452
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00540194
CST7 cystatin F (leukocystatin) -0.0053951
PIP prolactin-induced protein -0.00538305
SQSTM1 sequestosome 1 -0.00538238
SCGB1D2 secretoglobin, family 1D, member 2 -0.00538218
DLK1 delta-like 1 homolog (Drosophila) -0.00537708
PTPRK protein tyrosine phosphatase, receptor type, K -0.00537413
CTSG cathepsin G -0.00536879
SPEN spen family transcriptional repressor -0.00536196
RPL10 ribosomal protein L10 -0.00536189
JCHAIN joining chain of multimeric IgA and IgM -0.00534701
RAB38 RAB38, member RAS oncogene family -0.00534387
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00534273
ATXN1 ataxin 1 -0.00533244
NASP nuclear autoantigenic sperm protein (histone-binding) -0.00532681
PRTN3 proteinase 3 -0.00532236
STK38 serine/threonine kinase 38 -0.00531987
CAPN2 calpain 2, (m/II) large subunit -0.00529878
WDR19 WD repeat domain 19 -0.00528717
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -0.00527474
ALB albumin -0.00526009
CCL5 chemokine (C-C motif) ligand 5 -0.00525426
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00524514
GRAMD2B GRAM domain containing 2B -0.00520465
MAGEA12 melanoma antigen family A12 -0.00520093
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00519278
RUNX3 runt-related transcription factor 3 -0.00518899
SFRP1 secreted frizzled-related protein 1 -0.00516645
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00514089
MMP9 matrix metallopeptidase 9 -0.00513664
CHD4 chromodomain helicase DNA binding protein 4 -0.00513616
DEFB1 defensin, beta 1 -0.00513259
VNN1 vanin 1 -0.00512675
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.00508372
CBX1 chromobox homolog 1 -0.00508126
PLXNB2 plexin B2 -0.00507232
MCM3AP minichromosome maintenance complex component 3 associated protein -0.00507085
CRP C-reactive protein, pentraxin-related -0.00505648
AHCYL1 adenosylhomocysteinase-like 1 -0.00505045
SRSF1 serine/arginine-rich splicing factor 1 -0.00505031
C14ORF132 chromosome 14 open reading frame 132 -0.00504796
SST somatostatin -0.00502684
CSAD cysteine sulfinic acid decarboxylase -0.00502334
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.0050136
NID1 nidogen 1 -0.00501351
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.00500993
PAEP progestagen-associated endometrial protein -0.00500601
FAM117A family with sequence similarity 117, member A -0.00499909
DVL3 dishevelled segment polarity protein 3 -0.00499678
SOX11 SRY (sex determining region Y)-box 11 -0.00499289
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00498923
COL6A2 collagen, type VI, alpha 2 -0.00498884
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00498434
HCRT hypocretin (orexin) neuropeptide precursor -0.00498388
CENPE centromere protein E, 312kDa -0.00497241
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.00494285
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.0049258
NCAM1 neural cell adhesion molecule 1 -0.00491773
OLFM1 olfactomedin 1 -0.00491744
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00489726
FTH1 ferritin, heavy polypeptide 1 -0.00488745
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00485565
NIT1 nitrilase 1 -0.0048554
MCL1 myeloid cell leukemia 1 -0.0048518
CDC34 cell division cycle 34 -0.00484659
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00483646
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 -0.00483556
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00483372
KAZN kazrin, periplakin interacting protein -0.00483089
KAT2B K(lysine) acetyltransferase 2B -0.00481675
HIC2 hypermethylated in cancer 2 -0.00481199
SLTM SAFB-like, transcription modulator -0.0048047
HMGN5 high mobility group nucleosome binding domain 5 -0.00480461
PRDX6 peroxiredoxin 6 -0.00480439
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00480258
ZWINT ZW10 interacting kinetochore protein -0.00479878
RTN2 reticulon 2 -0.00479788
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.00478919
APOA1 apolipoprotein A-I -0.00478543
FBLN1 fibulin 1 -0.00478188
SLC43A3 solute carrier family 43, member 3 -0.0047811
FBXL7 F-box and leucine-rich repeat protein 7 -0.00476091
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -0.00475906
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00475643
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.00475206
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0047477
FAM193A family with sequence similarity 193, member A -0.00474755
ZCCHC14 zinc finger, CCHC domain containing 14 -0.00474378
TASOR2 transcription activation suppressor family member 2 -0.00474032
TULP3 tubby like protein 3 -0.00473916
PDZK1 PDZ domain containing 1 -0.00473365
C2CD3 C2 calcium-dependent domain containing 3 -0.00473179
WNT5A wingless-type MMTV integration site family, member 5A -0.00473013
SNAI2 snail family zinc finger 2 -0.00472608
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00472326
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00470151
FAM193B family with sequence similarity 193, member B -0.00469394
CCL4 chemokine (C-C motif) ligand 4 -0.00469261
NOTCH2 notch 2 -0.00468905
SLC35E2B solute carrier family 35, member E2B -0.00468852
SHOX2 short stature homeobox 2 -0.00468501
FHOD3 formin homology 2 domain containing 3 -0.00468098
PEG10 paternally expressed 10 -0.00467278
TNIP2 TNFAIP3 interacting protein 2 -0.00467265
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 -0.00466682
NXF1 nuclear RNA export factor 1 -0.00465256
MEX3D mex-3 RNA binding family member D -0.00464828
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00464125
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -0.00463347
TRAPPC10 trafficking protein particle complex 10 -0.00463231
APMAP adipocyte plasma membrane associated protein -0.00462212
CCP110 centriolar coiled coil protein 110kDa -0.00461779
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00461739
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00461397
TUT4 terminal uridylyl transferase 4 -0.00459918
KIAA0930 KIAA0930 -0.00459484
CAPRIN2 caprin family member 2 -0.00458684
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.00458672
ALOX5 arachidonate 5-lipoxygenase -0.00457972
APOB apolipoprotein B -0.00456115
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -0.00455469
PDGFD platelet derived growth factor D -0.00454639
CTSF cathepsin F -0.00453781
CLU clusterin -0.00453013
IGHMBP2 immunoglobulin mu binding protein 2 -0.00452783
COTL1 coactosin-like F-actin binding protein 1 -0.00451039
PNPLA6 patatin-like phospholipase domain containing 6 -0.00450637
EIF5A eukaryotic translation initiation factor 5A -0.0045059
SELENBP1 selenium binding protein 1 -0.00450438
LRRC41 leucine rich repeat containing 41 -0.00450396
UROD uroporphyrinogen decarboxylase -0.00450348
ADAM10 ADAM metallopeptidase domain 10 -0.00449865
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B -0.00449595
KRT17 keratin 17, type I -0.00449308
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -0.00446777