PIF1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PIF1 5'-to-3' DNA helicase|This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013] (NCBI Entrez Gene Database, 80119)
External Link http://www.ncbi.nlm.nih.gov/gene/80119
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Genes

6 interacting proteins for PIF1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
DKC1 dyskeratosis congenita 1, dyskerin
HNF4A hepatocyte nuclear factor 4, alpha
HSF2 heat shock transcription factor 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
TERT telomerase reverse transcriptase