Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
Category | transcriptomics |
Type | gene perturbation |
Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
External Link | http://www.broadinstitute.org/gsea/msigdb/cards/PIGF_UP.V1_UP |
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383 genes differentially expressed following the PIGF_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
Symbol | Name |
---|---|
ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
ADAM9 | ADAM metallopeptidase domain 9 |
AGA | aspartylglucosaminidase |
AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
AHCYL2 | adenosylhomocysteinase-like 2 |
AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
AKAP9 | A kinase (PRKA) anchor protein 9 |
AMPH | amphiphysin |
ANAPC13 | anaphase promoting complex subunit 13 |
ANGPT2 | angiopoietin 2 |
ARL4A | ADP-ribosylation factor-like 4A |
ARMC6 | armadillo repeat containing 6 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
ASCC3 | activating signal cointegrator 1 complex subunit 3 |
ATP13A3 | ATPase type 13A3 |
ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
ATR | ATR serine/threonine kinase |
BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
BCAS2 | breast carcinoma amplified sequence 2 |
BCLAF1 | BCL2-associated transcription factor 1 |
BPGM | 2,3-bisphosphoglycerate mutase |
C9ORF114 | chromosome 9 open reading frame 114 |
CALB2 | calbindin 2 |
CCL22 | chemokine (C-C motif) ligand 22 |
CCPG1 | cell cycle progression 1 |
CD2AP | CD2-associated protein |
CDC27 | cell division cycle 27 |
CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
CEP350 | centrosomal protein 350kDa |
CFH | complement factor H |
CLEC2B | C-type lectin domain family 2, member B |
COL8A1 | collagen, type VIII, alpha 1 |
CPA3 | carboxypeptidase A3 (mast cell) |
CPD | carboxypeptidase D |
CR2 | complement component (3d/Epstein Barr virus) receptor 2 |
CREB1 | cAMP responsive element binding protein 1 |
CRYBG3 | beta-gamma crystallin domain containing 3 |
CRYZ | crystallin, zeta (quinone reductase) |
DCP2 | decapping mRNA 2 |
DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 |
DMTF1 | cyclin D binding myb-like transcription factor 1 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
DNASE2 | deoxyribonuclease II, lysosomal |
DZIP1 | DAZ interacting zinc finger protein 1 |
EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
F11 | coagulation factor XI |
FABP4 | fatty acid binding protein 4, adipocyte |
FAM208A | family with sequence similarity 208, member A |
GGCX | gamma-glutamyl carboxylase |
GJA4 | gap junction protein, alpha 4, 37kDa |
GLRB | glycine receptor, beta |
GMFB | glia maturation factor, beta |
GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
GRB14 | growth factor receptor-bound protein 14 |
HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
HIST1H2BM | histone cluster 1, H2bm |
HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 |
HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 |
HSPA13 | heat shock protein 70kDa family, member 13 |
IL1RL1 | interleukin 1 receptor-like 1 |
IL6ST | interleukin 6 signal transducer |
IRAK1BP1 | interleukin-1 receptor-associated kinase 1 binding protein 1 |
IREB2 | iron-responsive element binding protein 2 |
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
ITSN2 | intersectin 2 |
KIAA0040 | KIAA0040 |
KIAA1033 | KIAA1033 |
KIF5B | kinesin family member 5B |
KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
LARP4 | La ribonucleoprotein domain family, member 4 |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
LRRC17 | leucine rich repeat containing 17 |
LTBP1 | latent transforming growth factor beta binding protein 1 |
MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) |
MAP2K4 | mitogen-activated protein kinase kinase 4 |
MAPK6 | mitogen-activated protein kinase 6 |
MARCH7 | membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase |
MARK2 | MAP/microtubule affinity-regulating kinase 2 |
MAST2 | microtubule associated serine/threonine kinase 2 |
MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
MICU2 | mitochondrial calcium uptake 2 |
MIPEP | mitochondrial intermediate peptidase |
MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
MMP10 | matrix metallopeptidase 10 |
MMRN1 | multimerin 1 |
MTF2 | metal response element binding transcription factor 2 |
MTM1 | myotubularin 1 |
N4BP2L2 | NEDD4 binding protein 2-like 2 |
NAP1L3 | nucleosome assembly protein 1-like 3 |
NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
NECAP1 | NECAP endocytosis associated 1 |
NEK1 | NIMA-related kinase 1 |
NEK7 | NIMA-related kinase 7 |
NRCAM | neuronal cell adhesion molecule |
NUCB2 | nucleobindin 2 |
NUP155 | nucleoporin 155kDa |
OPA1 | optic atrophy 1 (autosomal dominant) |
OSBPL8 | oxysterol binding protein-like 8 |
PAPOLA | poly(A) polymerase alpha |
PCDHA12 | protocadherin alpha 12 |
PDCD10 | programmed cell death 10 |
PEX1 | peroxisomal biogenesis factor 1 |
PGAP1 | post-GPI attachment to proteins 1 |
PHEX | phosphate regulating endopeptidase homolog, X-linked |
PHF3 | PHD finger protein 3 |
PISD | phosphatidylserine decarboxylase |
PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
PPAT | phosphoribosyl pyrophosphate amidotransferase |
PPID | peptidylprolyl isomerase D |
PPIG | peptidylprolyl isomerase G (cyclophilin G) |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PSPH | phosphoserine phosphatase |
PSPHP1 | phosphoserine phosphatase pseudogene 1 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
RAP1A | RAP1A, member of RAS oncogene family |
RARB | retinoic acid receptor, beta |
RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
RECQL | RecQ helicase-like |
REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
RFK | riboflavin kinase |
RGS2 | regulator of G-protein signaling 2 |
RIF1 | replication timing regulatory factor 1 |
RIPK2 | receptor-interacting serine-threonine kinase 2 |
RNF13 | ring finger protein 13 |
RNF6 | ring finger protein (C3H2C3 type) 6 |
ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
RPGR | retinitis pigmentosa GTPase regulator |
RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
SACS | sacsin molecular chaperone |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCAF11 | SR-related CTD-associated factor 11 |
SGMS1 | sphingomyelin synthase 1 |
SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
SLC38A6 | solute carrier family 38, member 6 |
SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
SMC3 | structural maintenance of chromosomes 3 |
SMC4 | structural maintenance of chromosomes 4 |
SOCS5 | suppressor of cytokine signaling 5 |
SP3 | Sp3 transcription factor |
SPRYD7 | SPRY domain containing 7 |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 |
STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
STAU2 | staufen double-stranded RNA binding protein 2 |
STK38L | serine/threonine kinase 38 like |
STON1 | stonin 1 |
STXBP3 | syntaxin binding protein 3 |
SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit |
SULF1 | sulfatase 1 |
SYNE2 | spectrin repeat containing, nuclear envelope 2 |
TAF9 | TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa |
TDG | thymine-DNA glycosylase |
TDP2 | tyrosyl-DNA phosphodiesterase 2 |
TDRD3 | tudor domain containing 3 |
TFPI2 | tissue factor pathway inhibitor 2 |
TGFBR3 | transforming growth factor, beta receptor III |
THOC2 | THO complex 2 |
THSD7A | thrombospondin, type I, domain containing 7A |
TMED5 | transmembrane emp24 protein transport domain containing 5 |
TMEM259 | transmembrane protein 259 |
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
TRIP11 | thyroid hormone receptor interactor 11 |
TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
TSPAN8 | tetraspanin 8 |
TTC37 | tetratricopeptide repeat domain 37 |
TTR | transthyretin |
TWF1 | twinfilin actin binding protein 1 |
TWISTNB | TWIST neighbor |
UFL1 | UFM1-specific ligase 1 |
UGP2 | UDP-glucose pyrophosphorylase 2 |
UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) |
VCAN | versican |
XIST | X inactive specific transcript (non-protein coding) |
ZC3H14 | zinc finger CCCH-type containing 14 |
ZNF117 | zinc finger protein 117 |
ZNF268 | zinc finger protein 268 |
ZNF354A | zinc finger protein 354A |
ZNF451 | zinc finger protein 451 |
ZNF674 | zinc finger protein 674 |
ZZZ3 | zinc finger, ZZ-type containing 3 |
Symbol | Name |
---|---|
ACAT2 | acetyl-CoA acetyltransferase 2 |
ACTL6B | actin-like 6B |
ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
AK4 | adenylate kinase 4 |
ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
AMELX | amelogenin, X-linked |
ANGEL1 | angel homolog 1 (Drosophila) |
AOC4P | amine oxidase, copper containing 4, pseudogene |
APOC1 | apolipoprotein C-I |
ARC | activity-regulated cytoskeleton-associated protein |
ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
AURKC | aurora kinase C |
AVPR1B | arginine vasopressin receptor 1B |
BCAM | basal cell adhesion molecule (Lutheran blood group) |
BMP2 | bone morphogenetic protein 2 |
C21ORF2 | chromosome 21 open reading frame 2 |
C22ORF24 | chromosome 22 open reading frame 24 |
C9 | complement component 9 |
CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
CCDC9 | coiled-coil domain containing 9 |
CCL16 | chemokine (C-C motif) ligand 16 |
CD5 | CD5 molecule |
CDC20 | cell division cycle 20 |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CFAP20 | cilia and flagella associated protein 20 |
CLASRP | CLK4-associating serine/arginine rich protein |
CLDN9 | claudin 9 |
CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
COL11A2 | collagen, type XI, alpha 2 |
COL18A1 | collagen, type XVIII, alpha 1 |
CREBZF | CREB/ATF bZIP transcription factor |
CRX | cone-rod homeobox |
CSHL1 | chorionic somatomammotropin hormone-like 1 |
CTF1 | cardiotrophin 1 |
CTRL | chymotrypsin-like |
CTSW | cathepsin W |
CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
CYP2A13 | cytochrome P450, family 2, subfamily A, polypeptide 13 |
DAAM2 | dishevelled associated activator of morphogenesis 2 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
DHCR24 | 24-dehydrocholesterol reductase |
DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
DLEC1 | deleted in lung and esophageal cancer 1 |
DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
DOLPP1 | dolichyldiphosphatase 1 |
DPF1 | D4, zinc and double PHD fingers family 1 |
EDN2 | endothelin 2 |
EFNA5 | ephrin-A5 |
ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 |
ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
ERF | Ets2 repressor factor |
ERVK-6 | endogenous retrovirus group K, member 6 |
EVPL | envoplakin |
FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
FGA | fibrinogen alpha chain |
FOXG1 | forkhead box G1 |
FZD7 | frizzled class receptor 7 |
GATA4 | GATA binding protein 4 |
GFRA2 | GDNF family receptor alpha 2 |
GH1 | growth hormone 1 |
GLYAT | glycine-N-acyltransferase |
GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
GNB3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 |
GPR17 | G protein-coupled receptor 17 |
GPR182 | G protein-coupled receptor 182 |
GPR37L1 | G protein-coupled receptor 37 like 1 |
GRAP2 | GRB2-related adaptor protein 2 |
GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
GRM2 | glutamate receptor, metabotropic 2 |
GSTTP2 | glutathione S-transferase theta pseudogene 2 |
GYPC | glycophorin C (Gerbich blood group) |
HBZ | hemoglobin, zeta |
HOMER2 | homer scaffolding protein 2 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGFBP5 | insulin-like growth factor binding protein 5 |
IGFBP6 | insulin-like growth factor binding protein 6 |
IGHA2 | immunoglobulin heavy constant alpha 2 (A2m marker) |
IQCK | IQ motif containing K |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
ITGB4 | integrin, beta 4 |
KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
KCNC3 | potassium channel, voltage gated Shaw related subfamily C, member 3 |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
KLK10 | kallikrein-related peptidase 10 |
KRT31 | keratin 31, type I |
KRT9 | keratin 9, type I |
LOC441178 | uncharacterized LOC441178 |
LOC730101 | uncharacterized LOC730101 |
LOXL1 | lysyl oxidase-like 1 |
LRRC23 | leucine rich repeat containing 23 |
LTK | leukocyte receptor tyrosine kinase |
LY6E | lymphocyte antigen 6 complex, locus E |
MAP1A | microtubule-associated protein 1A |
MAST1 | microtubule associated serine/threonine kinase 1 |
MCF2L | MCF.2 cell line derived transforming sequence-like |
MEF2B | myocyte enhancer factor 2B |
MSI1 | musashi RNA-binding protein 1 |
MTSS1L | metastasis suppressor 1-like |
MYL9 | myosin, light chain 9, regulatory |
MYO1F | myosin IF |
MYOG | myogenin (myogenic factor 4) |
NCAM1 | neural cell adhesion molecule 1 |
NCR3 | natural cytotoxicity triggering receptor 3 |
NELL2 | NEL-like 2 (chicken) |
NFASC | neurofascin |
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
NOS2 | nitric oxide synthase 2, inducible |
NOX1 | NADPH oxidase 1 |
NPAS3 | neuronal PAS domain protein 3 |
NPR2 | natriuretic peptide receptor 2 |
NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
NUCB1 | nucleobindin 1 |
OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
PAIP2B | poly(A) binding protein interacting protein 2B |
PAX2 | paired box 2 |
PDE1B | phosphodiesterase 1B, calmodulin-dependent |
PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
PDPN | podoplanin |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
PITX3 | paired-like homeodomain 3 |
PKD1 | polycystic kidney disease 1 (autosomal dominant) |
PKLR | pyruvate kinase, liver and RBC |
PKP3 | plakophilin 3 |
POU2F3 | POU class 2 homeobox 3 |
PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
PRPF19 | pre-mRNA processing factor 19 |
PSG11 | pregnancy specific beta-1-glycoprotein 11 |
PTGFR | prostaglandin F receptor (FP) |
PTPRH | protein tyrosine phosphatase, receptor type, H |
PTPRU | protein tyrosine phosphatase, receptor type, U |
PXN | paxillin |
RAB5C | RAB5C, member RAS oncogene family |
RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
RIMS3 | regulating synaptic membrane exocytosis 3 |
RPS4Y1 | ribosomal protein S4, Y-linked 1 |
RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) |
S100A4 | S100 calcium binding protein A4 |
SDC4 | syndecan 4 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SH3BP1 | SH3-domain binding protein 1 |
SHBG | sex hormone-binding globulin |
SHH | sonic hedgehog |
SLC14A2 | solute carrier family 14 (urea transporter), member 2 |
SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
SLC30A10 | solute carrier family 30, member 10 |
SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 |
SMG6 | SMG6 nonsense mediated mRNA decay factor |
SNX29 | sorting nexin 29 |
SPN | sialophorin |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
SPTB | spectrin, beta, erythrocytic |
SRCAP | Snf2-related CREBBP activator protein |
SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
SSTR2 | somatostatin receptor 2 |
SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
TAOK2 | TAO kinase 2 |
TAS2R14 | taste receptor, type 2, member 14 |
THY1 | Thy-1 cell surface antigen |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TMEM97 | transmembrane protein 97 |
TMSB4Y | thymosin beta 4, Y-linked |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
TOP3B | topoisomerase (DNA) III beta |
TPTEP1 | transmembrane phosphatase with tensin homology pseudogene 1 |
TRIO | trio Rho guanine nucleotide exchange factor |
TROAP | trophinin associated protein |
TTLL3 | tubulin tyrosine ligase-like family member 3 |
UBE2H | ubiquitin-conjugating enzyme E2H |
USP9Y | ubiquitin specific peptidase 9, Y-linked |
UTF1 | undifferentiated embryonic cell transcription factor 1 |
VGF | VGF nerve growth factor inducible |
ZFHX2 | zinc finger homeobox 2 |
ZFR2 | zinc finger RNA binding protein 2 |
ZNF185 | zinc finger protein 185 (LIM domain) |
ZNF646 | zinc finger protein 646 |