PIGS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description phosphatidylinositol glycan anchor biosynthesis, class S|This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 94005)
External Link http://www.ncbi.nlm.nih.gov/gene/94005
Similar Terms
Downloads & Tools

Genes

307 interacting proteins for PIGS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACADVL acyl-CoA dehydrogenase, very long chain
ACBD5 acyl-CoA binding domain containing 5
ACP1 acid phosphatase 1, soluble
ACP2 acid phosphatase 2, lysosomal
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTB actin, beta
ADAP1 ArfGAP with dual PH domains 1
ADD1 adducin 1 (alpha)
ADD3 adducin 3 (gamma)
ADGRE5 adhesion G protein-coupled receptor E5
ADNP activity-dependent neuroprotector homeobox
AGPS alkylglycerone phosphate synthase
AHNAK AHNAK nucleoprotein
AIP aryl hydrocarbon receptor interacting protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APMAP adipocyte plasma membrane associated protein
ARCN1 archain 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARF6 ADP-ribosylation factor 6
ARHGAP1 Rho GTPase activating protein 1
ARHGAP8 Rho GTPase activating protein 8
ARL1 ADP-ribosylation factor-like 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
B3GAT3 beta-1,3-glucuronyltransferase 3
BSG basigin (Ok blood group)
BTD biotinidase
BTN2A1 butyrophilin, subfamily 2, member A1
BZW1 basic leucine zipper and W2 domains 1
BZW2 basic leucine zipper and W2 domains 2
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CD109 CD109 molecule
CD276 CD276 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CFL1 cofilin 1 (non-muscle)
CHMP2A charged multivesicular body protein 2A
CHMP4B charged multivesicular body protein 4B
CLIC1 chloride intracellular channel 1
CLN5 ceroid-lipofuscinosis, neuronal 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLTC clathrin, heavy chain (Hc)
CLU clusterin
CNN2 calponin 2
COL5A1 collagen, type V, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COPA coatomer protein complex, subunit alpha
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRTAP cartilage associated protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSD cathepsin D
CUL3 cullin 3
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYTH1 cytohesin 1
CYTH2 cytohesin 2
CYTH3 cytohesin 3
DIAPH1 diaphanous-related formin 1
DNASE2 deoxyribonuclease II, lysosomal
DNM2 dynamin 2
DPP7 dipeptidyl-peptidase 7
DRG1 developmentally regulated GTP binding protein 1
DSG1 desmoglein 1
DSTN destrin (actin depolymerizing factor)
DTYMK deoxythymidylate kinase (thymidylate kinase)
DUSP23 dual specificity phosphatase 23
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECE1 endothelin converting enzyme 1
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
EMC1 ER membrane protein complex subunit 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPCAM epithelial cell adhesion molecule
ERAP1 endoplasmic reticulum aminopeptidase 1
ERO1L ERO1-like (S. cerevisiae)
ESYT1 extended synaptotagmin-like protein 1
ETHE1 ethylmalonic encephalopathy 1
EYS eyes shut homolog (Drosophila)
FANCI Fanconi anemia, complementation group I
FAR2 fatty acyl CoA reductase 2
FASN fatty acid synthase
FBN1 fibrillin 1
FBXO6 F-box protein 6
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP9 FK506 binding protein 9, 63 kDa
FNTA farnesyltransferase, CAAX box, alpha
FOLR1 folate receptor 1 (adult)
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
G6PD glucose-6-phosphate dehydrogenase
GAA glucosidase, alpha; acid
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA glucosidase, beta, acid
GBAS glioblastoma amplified sequence
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GLMP glycosylated lysosomal membrane protein
GNPAT glyceronephosphate O-acyltransferase
GNS glucosamine (N-acetyl)-6-sulfatase
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GUSB glucuronidase, beta
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HEXA hexosaminidase A (alpha polypeptide)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-H major histocompatibility complex, class I, H (pseudogene)
HNF4A hepatocyte nuclear factor 4, alpha
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA13 heat shock protein 70kDa family, member 13
HSPA1L heat shock 70kDa protein 1-like
HYOU1 hypoxia up-regulated 1
IGF2R insulin-like growth factor 2 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB4 integrin, beta 4
KIAA0368 KIAA0368
KIF5B kinesin family member 5B
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LBR lamin B receptor
LDHA lactate dehydrogenase A
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGALS4 lectin, galactoside-binding, soluble, 4
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LMAN1 lectin, mannose-binding, 1
LNPEP leucyl/cystinyl aminopeptidase
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC59 leucine rich repeat containing 59
M6PR mannose-6-phosphate receptor (cation dependent)
MAN2B1 mannosidase, alpha, class 2B, member 1
MAPK1 mitogen-activated protein kinase 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MX1 MX dynamin-like GTPase 1
MYH14 myosin, heavy chain 14, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MYO18A myosin XVIIIA
MYO1E myosin IE
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NACA nascent polypeptide-associated complex alpha subunit
NCEH1 neutral cholesterol ester hydrolase 1
NCSTN nicastrin
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NOMO1 NODAL modulator 1
NPC1 Niemann-Pick disease, type C1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NSF N-ethylmaleimide-sensitive factor
NTPCR nucleoside-triphosphatase, cancer-related
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
NUP210 nucleoporin 210kDa
P3H1 prolyl 3-hydroxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCYOX1 prenylcysteine oxidase 1
PDS5A PDS5 cohesin associated factor A
PDZD8 PDZ domain containing 8
PFKL phosphofructokinase, liver
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PHB prohibitin
PHGDH phosphoglycerate dehydrogenase
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGR polymeric immunoglobulin receptor
PIGT phosphatidylinositol glycan anchor biosynthesis, class T
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PITPNB phosphatidylinositol transfer protein, beta
PKM pyruvate kinase, muscle
PKN2 protein kinase N2
PLA2G15 phospholipase A2, group XV
PLAUR plasminogen activator, urokinase receptor
PLEK2 pleckstrin 2
PLLP plasmolipin
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLS1 plastin 1
PLXNB2 plexin B2
PODXL2 podocalyxin-like 2
POTEE POTE ankyrin domain family, member E
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPT1 palmitoyl-protein thioesterase 1
PSAP prosaposin
PTGES2 prostaglandin E synthase 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB11A RAB11A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
REPS1 RALBP1 associated Eps domain containing 1
RHEB Ras homolog enriched in brain
RPN1 ribophorin I
RPN2 ribophorin II
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRAS related RAS viral (r-ras) oncogene homolog
SAR1A secretion associated, Ras related GTPase 1A
SARNP SAP domain containing ribonucleoprotein
SCARB1 scavenger receptor class B, member 1
SCARB2 scavenger receptor class B, member 2
SCCPDH saccharopine dehydrogenase (putative)
SCP2 sterol carrier protein 2
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT11 septin 11
SEPT2 septin 2
SEPT7 septin 7
SEPT9 septin 9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETD3 SET domain containing 3
SFXN1 sideroflexin 1
SGPL1 sphingosine-1-phosphate lyase 1
SGSH N-sulfoglucosamine sulfohydrolase
SIAE sialic acid acetylesterase
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SNAPIN SNAP-associated protein
SNX5 sorting nexin 5
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
SQRDL sulfide quinone reductase-like (yeast)
SRP54 signal recognition particle 54kDa
SRP72 signal recognition particle 72kDa
SRP9 signal recognition particle 9kDa
SRPK1 SRSF protein kinase 1
SSR1 signal sequence receptor, alpha
SSRP1 structure specific recognition protein 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STOM stomatin
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
STXBP5 syntaxin binding protein 5 (tomosyn)
SUMF1 sulfatase modifying factor 1
SUN2 Sad1 and UNC84 domain containing 2
TAGLN2 transgelin 2
TBC1D4 TBC1 domain family, member 4
TFRC transferrin receptor
TLN1 talin 1
TMEM109 transmembrane protein 109
TMEM33 transmembrane protein 33
TMOD2 tropomodulin 2 (neuronal)
TMOD3 tropomodulin 3 (ubiquitous)
TMX3 thioredoxin-related transmembrane protein 3
TPBG trophoblast glycoprotein
TPD52 tumor protein D52
TPD52L2 tumor protein D52-like 2
TPM3 tropomyosin 3
TPP1 tripeptidyl peptidase I
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIM28 tripartite motif containing 28
TSPAN8 tetraspanin 8
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TTC39B tetratricopeptide repeat domain 39B
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TXNDC15 thioredoxin domain containing 15
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UCK2 uridine-cytidine kinase 2
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VSNL1 visinin-like 1
VTA1 vesicle (multivesicular body) trafficking 1
XPO1 exportin 1
XPO7 exportin 7
ZC3H15 zinc finger CCCH-type containing 15