PIGT Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description phosphatidylinositol glycan anchor biosynthesis, class T|This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] (NCBI Entrez Gene Database, 51604)
External Link http://www.ncbi.nlm.nih.gov/gene/51604
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Genes

111 interacting proteins for PIGT from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACP2 acid phosphatase 2, lysosomal
ADGRE5 adhesion G protein-coupled receptor E5
ADNP activity-dependent neuroprotector homeobox
APMAP adipocyte plasma membrane associated protein
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
BSG basigin (Ok blood group)
BTD biotinidase
BTN2A1 butyrophilin, subfamily 2, member A1
CD109 CD109 molecule
CD276 CD276 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CLN5 ceroid-lipofuscinosis, neuronal 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLU clusterin
COL5A1 collagen, type V, alpha 1
COLGALT1 collagen beta(1-O)galactosyltransferase 1
CRTAP cartilage associated protein
CTSD cathepsin D
DNASE2 deoxyribonuclease II, lysosomal
DPP7 dipeptidyl-peptidase 7
DSG1 desmoglein 1
ECE1 endothelin converting enzyme 1
EMC1 ER membrane protein complex subunit 1
ERO1L ERO1-like (S. cerevisiae)
EYS eyes shut homolog (Drosophila)
FBN1 fibrillin 1
FKBP10 FK506 binding protein 10, 65 kDa
FKBP9 FK506 binding protein 9, 63 kDa
FOLR1 folate receptor 1 (adult)
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
GAA glucosidase, alpha; acid
GBA glucosidase, beta, acid
GLMP glycosylated lysosomal membrane protein
GNS glucosamine (N-acetyl)-6-sulfatase
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GUSB glucuronidase, beta
HEXA hexosaminidase A (alpha polypeptide)
HNF4A hepatocyte nuclear factor 4, alpha
HSPA13 heat shock protein 70kDa family, member 13
HYOU1 hypoxia up-regulated 1
IGF2R insulin-like growth factor 2 receptor
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
L1CAM L1 cell adhesion molecule
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LNPEP leucyl/cystinyl aminopeptidase
M6PR mannose-6-phosphate receptor (cation dependent)
MAN2B1 mannosidase, alpha, class 2B, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
NCEH1 neutral cholesterol ester hydrolase 1
NCSTN nicastrin
NOMO1 NODAL modulator 1
NPC1 Niemann-Pick disease, type C1
NRF1 nuclear respiratory factor 1
NUP210 nucleoporin 210kDa
P3H1 prolyl 3-hydroxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCYOX1 prenylcysteine oxidase 1
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PIGR polymeric immunoglobulin receptor
PIGS phosphatidylinositol glycan anchor biosynthesis, class S
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PLA2G15 phospholipase A2, group XV
PLAUR plasminogen activator, urokinase receptor
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PLXNB2 plexin B2
PODXL2 podocalyxin-like 2
PPT1 palmitoyl-protein thioesterase 1
PSAP prosaposin
SCARB1 scavenger receptor class B, member 1
SCARB2 scavenger receptor class B, member 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SETD3 SET domain containing 3
SGSH N-sulfoglucosamine sulfohydrolase
SIAE sialic acid acetylesterase
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SSR1 signal sequence receptor, alpha
STOM stomatin
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
SUMF1 sulfatase modifying factor 1
SUMO2 small ubiquitin-like modifier 2
SUN2 Sad1 and UNC84 domain containing 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFRC transferrin receptor
TMX3 thioredoxin-related transmembrane protein 3
TPBG trophoblast glycoprotein
TPP1 tripeptidyl peptidase I
TREML2 triggering receptor expressed on myeloid cells-like 2
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
TXNDC15 thioredoxin domain containing 15
UBC ubiquitin C
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)