| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha|Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5290) |
| External Link | https://ncbi.nlm.nih.gov/gene/5290 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PIK3CA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0172964 |
| AGR2 | anterior gradient 2 | 0.0146867 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.0138897 |
| S100P | S100 calcium binding protein P | 0.013423 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0128881 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.011951 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.0110778 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0109998 |
| MAP7 | microtubule-associated protein 7 | 0.0109815 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.0109078 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0108411 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0104444 |
| TSPAN8 | tetraspanin 8 | 0.0104421 |
| F2R | coagulation factor II (thrombin) receptor | 0.010296 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.0100631 |
| CCNB1 | cyclin B1 | 0.00996824 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00980857 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00968735 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00964188 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00960008 |
| CST3 | cystatin C | 0.00945311 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00938406 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00934904 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00924783 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00921943 |
| MTMR11 | myotubularin related protein 11 | 0.00915644 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00909557 |
| PRR7 | proline rich 7 (synaptic) | 0.00898181 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00886957 |
| METRN | meteorin, glial cell differentiation regulator | 0.00883903 |
| KRT20 | keratin 20, type I | 0.00882609 |
| TFF1 | trefoil factor 1 | 0.00875666 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00871991 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00869668 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00863611 |
| CYBRD1 | cytochrome b reductase 1 | 0.00857722 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00852392 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 0.00851144 |
| TPD52 | tumor protein D52 | 0.0084892 |
| HOPX | HOP homeobox | 0.00840488 |
| DNASE2 | deoxyribonuclease II, lysosomal | 0.00829599 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00828036 |
| CD9 | CD9 molecule | 0.00823445 |
| KRT19 | keratin 19, type I | 0.0082284 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00822069 |
| GATA3 | GATA binding protein 3 | 0.00812417 |
| EMP3 | epithelial membrane protein 3 | 0.00810606 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00809692 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00802184 |
| DUOX2 | dual oxidase 2 | 0.00800604 |
| F12 | coagulation factor XII (Hageman factor) | 0.00799332 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00793843 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.00788364 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.00775866 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00771648 |
| CLCA1 | chloride channel accessory 1 | 0.00771112 |
| NUP85 | nucleoporin 85kDa | 0.00768715 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00767777 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00766592 |
| ACOT9 | acyl-CoA thioesterase 9 | 0.00759234 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00757261 |
| CLDN1 | claudin 1 | 0.0075556 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00755442 |
| MYO1D | myosin ID | 0.00753723 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00751862 |
| BLVRB | biliverdin reductase B | 0.00749089 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00747616 |
| SPAG4 | sperm associated antigen 4 | 0.00747366 |
| DACH1 | dachshund family transcription factor 1 | 0.00741338 |
| TM4SF20 | transmembrane 4 L six family member 20 | 0.00740537 |
| C1R | complement component 1, r subcomponent | 0.00738501 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.00737664 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00736574 |
| BLNK | B-cell linker | 0.00732925 |
| ZNF217 | zinc finger protein 217 | 0.00731699 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.00730162 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0072912 |
| MMRN1 | multimerin 1 | 0.00728737 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00727802 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00725776 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00724961 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00717303 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00714441 |
| CTTN | cortactin | 0.00713659 |
| HEPH | hephaestin | 0.00713605 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.00713029 |
| HOXC6 | homeobox C6 | 0.00711532 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00706417 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00705785 |
| CTSK | cathepsin K | 0.00700022 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00693491 |
| SQOR | sulfide quinone oxidoreductase | 0.00687483 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00683459 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00683378 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.0068244 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00681915 |
| AREG | amphiregulin | 0.00681822 |
| MYLK | myosin light chain kinase | 0.00681533 |
| ANXA4 | annexin A4 | 0.00675669 |
| NKX3-1 | NK3 homeobox 1 | 0.00674201 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00673872 |
| HEXB | hexosaminidase B (beta polypeptide) | 0.00673677 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 0.00671368 |
| TUBA1A | tubulin, alpha 1a | 0.00671117 |
| DCN | decorin | 0.00670299 |
| C1RL | complement component 1, r subcomponent-like | 0.00668554 |
| CD99 | CD99 molecule | 0.00666297 |
| FST | follistatin | 0.00666262 |
| FABP1 | fatty acid binding protein 1, liver | 0.00665611 |
| ADA | adenosine deaminase | 0.00664995 |
| ADIRF | adipogenesis regulatory factor | 0.00664367 |
| TSPAN4 | tetraspanin 4 | 0.00660619 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00659215 |
| CAVIN2 | caveolae associated protein 2 | 0.00658493 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00658376 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00657734 |
| COLEC12 | collectin sub-family member 12 | 0.00657381 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00656806 |
| TSPAN31 | tetraspanin 31 | 0.00655623 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00653796 |
| TLR4 | toll-like receptor 4 | 0.0065228 |
| CPQ | carboxypeptidase Q | 0.00652025 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0065043 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00646355 |
| CLDN7 | claudin 7 | 0.0064402 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00642385 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0064214 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.00639981 |
| ALDOB | aldolase B, fructose-bisphosphate | 0.00638439 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00638171 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00637884 |
| TSPAN6 | tetraspanin 6 | 0.0063634 |
| MFAP5 | microfibrillar associated protein 5 | 0.00636001 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00635991 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00633454 |
| NTAN1 | N-terminal asparagine amidase | 0.00633402 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00631408 |
| IRF6 | interferon regulatory factor 6 | 0.00629489 |
| TCF4 | transcription factor 4 | 0.0062854 |
| HHEX | hematopoietically expressed homeobox | 0.00628232 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00627369 |
| CD44 | CD44 molecule (Indian blood group) | 0.00626976 |
| PALLD | palladin, cytoskeletal associated protein | 0.00626651 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.00622169 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00620458 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00620224 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00619326 |
| PBK | PDZ binding kinase | 0.00616342 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.00613475 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00612231 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00610867 |
| H1-10 | H1.10 linker histone | 0.00610021 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0060575 |
| EFHD2 | EF-hand domain family, member D2 | 0.00602889 |
| POF1B | premature ovarian failure, 1B | 0.00601366 |
| ADORA3 | adenosine A3 receptor | 0.0060112 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00600386 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00599961 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.00597315 |
| STAP2 | signal transducing adaptor family member 2 | 0.00596776 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00593632 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00591559 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00590284 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00590065 |
| GCHFR | GTP cyclohydrolase I feedback regulator | 0.00589944 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00589752 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.00588022 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.00587928 |
| IL18 | interleukin 18 | 0.00587606 |
| FAM198B | family with sequence similarity 198, member B | 0.00587426 |
| DCK | deoxycytidine kinase | 0.00587328 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00585062 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00583289 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | 0.00581483 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0058125 |
| MLF1 | myeloid leukemia factor 1 | 0.00580253 |
| MYO5C | myosin VC | 0.00575547 |
| GAS6 | growth arrest-specific 6 | 0.00575507 |
| ARL4A | ADP-ribosylation factor-like 4A | 0.00575441 |
| PON3 | paraoxonase 3 | 0.00574721 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00574602 |
| PLAT | plasminogen activator, tissue | 0.00571171 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.0056969 |
| TSPAN1 | tetraspanin 1 | 0.00569265 |
| ITGA6 | integrin, alpha 6 | 0.00568489 |
| ASB9 | ankyrin repeat and SOCS box containing 9 | 0.0056795 |
| RNASET2 | ribonuclease T2 | 0.00566997 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00565741 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00565517 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.00564153 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00563939 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00562727 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0056228 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00560506 |
| CDH13 | cadherin 13 | 0.00558765 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00556814 |
| RHOH | ras homolog family member H | 0.00556347 |
| LUM | lumican | 0.00555549 |
| TAGLN2 | transgelin 2 | 0.00555519 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00555396 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00554894 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00554296 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | 0.00552736 |
| G6PD | glucose-6-phosphate dehydrogenase | 0.00551011 |
| JAM3 | junctional adhesion molecule 3 | 0.00550383 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00549986 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.00549636 |
| SDC2 | syndecan 2 | 0.00548979 |
| PLPP3 | phospholipid phosphatase 3 | 0.00548809 |
| TCF21 | transcription factor 21 | 0.00547874 |
| CLCA2 | chloride channel accessory 2 | 0.00547774 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00547573 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.0054702 |
| CHPT1 | choline phosphotransferase 1 | 0.00546768 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00544881 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00544611 |
| FMO5 | flavin containing monooxygenase 5 | 0.00543516 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00543381 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 0.00542987 |
| HTRA2 | HtrA serine peptidase 2 | 0.00542356 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.00542073 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00540909 |
| ZNF768 | zinc finger protein 768 | 0.00540862 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00540209 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00539307 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00538583 |
| CERS2 | ceramide synthase 2 | 0.00538402 |
| VEZF1 | vascular endothelial zinc finger 1 | 0.00538374 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00538168 |
| MSL1 | male-specific lethal 1 homolog (Drosophila) | 0.00536279 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00535691 |
| HLTF | helicase-like transcription factor | 0.00535597 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00533946 |
| ZG16 | zymogen granule protein 16 | 0.00532198 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00531269 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00530517 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 | 0.00530121 |
| RNF167 | ring finger protein 167 | 0.00528458 |
| LY86 | lymphocyte antigen 86 | 0.00527799 |
| CTSS | cathepsin S | 0.00527373 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 | 0.00527015 |
| FCGBP | Fc fragment of IgG binding protein | 0.00526301 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00525762 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00525501 |
| THBS2 | thrombospondin 2 | 0.00525415 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.00525353 |
| LY96 | lymphocyte antigen 96 | 0.00523604 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.00523157 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00522185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0183714 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0168913 |
| COQ8A | coenzyme Q8A | -0.0155035 |
| ZNF586 | zinc finger protein 586 | -0.0142375 |
| E2F2 | E2F transcription factor 2 | -0.0127744 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0125481 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0117908 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | -0.0113644 |
| G0S2 | G0/G1 switch 2 | -0.0112371 |
| CYCS | cytochrome c, somatic | -0.011174 |
| HMOX1 | heme oxygenase 1 | -0.0108264 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0107257 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0107072 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.0105694 |
| MT1X | metallothionein 1X | -0.010562 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0104392 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.0103827 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0100445 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00992106 |
| ADM | adrenomedullin | -0.00977399 |
| PROM1 | prominin 1 | -0.00974125 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00968392 |
| PEG10 | paternally expressed 10 | -0.00948501 |
| S100B | S100 calcium binding protein B | -0.00944608 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00931388 |
| FOLR1 | folate receptor 1 (adult) | -0.00929316 |
| GGCT | gamma-glutamylcyclotransferase | -0.00928024 |
| MT1E | metallothionein 1E | -0.00925883 |
| CADM1 | cell adhesion molecule 1 | -0.00921467 |
| PODXL | podocalyxin-like | -0.00921144 |
| MT1G | metallothionein 1G | -0.00910557 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00902772 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00899118 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00887688 |
| NVL | nuclear VCP-like | -0.00881299 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00869051 |
| SPP1 | secreted phosphoprotein 1 | -0.00861951 |
| NEFH | neurofilament, heavy polypeptide | -0.00859318 |
| CST7 | cystatin F (leukocystatin) | -0.00857377 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.00853829 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00851434 |
| IL1RN | interleukin 1 receptor antagonist | -0.0084146 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00839972 |
| CD93 | CD93 molecule | -0.00837671 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00818822 |
| LYST | lysosomal trafficking regulator | -0.00802615 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00798759 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00795354 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00793947 |
| MT1H | metallothionein 1H | -0.00792235 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00791888 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00785742 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00780486 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00761959 |
| PDZD2 | PDZ domain containing 2 | -0.00754202 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0074806 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00747052 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00745078 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00743108 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.00740067 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00738354 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00735835 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00718414 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00714673 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.007129 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00709945 |
| MT1F | metallothionein 1F | -0.00705828 |
| AZU1 | azurocidin 1 | -0.00703463 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00700638 |
| MMP9 | matrix metallopeptidase 9 | -0.00700015 |
| VEGFA | vascular endothelial growth factor A | -0.00699857 |
| SEC61B | Sec61 beta subunit | -0.00697454 |
| CST6 | cystatin E/M | -0.00696233 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.00694727 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00688346 |
| PUM3 | pumilio RNA binding family member 3 | -0.00686761 |
| RBM34 | RNA binding motif protein 34 | -0.00686523 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00685532 |
| MEIS2 | Meis homeobox 2 | -0.00680221 |
| CCNB2 | cyclin B2 | -0.00678686 |
| CKM | creatine kinase, muscle | -0.00676955 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00674802 |
| ESRRG | estrogen-related receptor gamma | -0.00674761 |
| THBD | thrombomodulin | -0.00674268 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.00673321 |
| CDC20 | cell division cycle 20 | -0.00671858 |
| RET | ret proto-oncogene | -0.0066782 |
| RGCC | regulator of cell cycle | -0.00663292 |
| MT2A | metallothionein 2A | -0.00662971 |
| CDHR1 | cadherin-related family member 1 | -0.00659972 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00659588 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00659382 |
| VSNL1 | visinin-like 1 | -0.00658674 |
| MEN1 | multiple endocrine neoplasia I | -0.00657868 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.0065782 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.00656714 |
| ATF3 | activating transcription factor 3 | -0.00654886 |
| FAM149A | family with sequence similarity 149, member A | -0.0065138 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.00650037 |
| ASRGL1 | asparaginase like 1 | -0.00649998 |
| FOCAD | focadhesin | -0.00645736 |
| TNNC1 | troponin C type 1 (slow) | -0.00644874 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0064444 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.00640348 |
| EPHB2 | EPH receptor B2 | -0.006392 |
| CLCN4 | chloride channel, voltage-sensitive 4 | -0.00638744 |
| TADA2A | transcriptional adaptor 2A | -0.00637886 |
| KIF1A | kinesin family member 1A | -0.00636971 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00635924 |
| NFIB | nuclear factor I/B | -0.00634046 |
| AUTS2 | autism susceptibility candidate 2 | -0.0063396 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.00633011 |
| VTN | vitronectin | -0.00630677 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00630548 |
| STX18 | syntaxin 18 | -0.00629257 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00628389 |
| BAG3 | BCL2-associated athanogene 3 | -0.00627687 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00622696 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.00620397 |
| ELANE | elastase, neutrophil expressed | -0.00619334 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00619076 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00618125 |
| TXN | thioredoxin | -0.00613425 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00612916 |
| KRT14 | keratin 14, type I | -0.00611696 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.00608485 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00607398 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.00603891 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00602454 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | -0.00600739 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00600289 |
| PLCB4 | phospholipase C, beta 4 | -0.00599882 |
| CHMP4A | charged multivesicular body protein 4A | -0.00597304 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00597149 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00596964 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.00596681 |
| CS | citrate synthase | -0.00591616 |
| EGR1 | early growth response 1 | -0.00590887 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00589938 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00588784 |
| RCAN1 | regulator of calcineurin 1 | -0.00586731 |
| NPY | neuropeptide Y | -0.00586428 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00586113 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00585352 |
| CLDN10 | claudin 10 | -0.00583025 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00578642 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00578424 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.00577909 |
| HMGA2 | high mobility group AT-hook 2 | -0.00577389 |
| MAP1A | microtubule-associated protein 1A | -0.00576903 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.0057438 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00574143 |
| COBL | cordon-bleu WH2 repeat protein | -0.00573608 |
| CLEC5A | C-type lectin domain family 5, member A | -0.00571228 |
| LXN | latexin | -0.00570909 |
| STK10 | serine/threonine kinase 10 | -0.00569489 |
| SRPRA | SRP receptor subunit alpha | -0.00567177 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.005671 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.00566147 |
| RGS16 | regulator of G-protein signaling 16 | -0.00565622 |
| RGS3 | regulator of G-protein signaling 3 | -0.00564079 |
| SV2B | synaptic vesicle glycoprotein 2B | -0.00563209 |
| PLIN2 | perilipin 2 | -0.00563095 |
| COL5A2 | collagen, type V, alpha 2 | -0.00561528 |
| TSPYL5 | TSPY-like 5 | -0.00561015 |
| RUNX3 | runt-related transcription factor 3 | -0.00558071 |
| PKM | pyruvate kinase, muscle | -0.00557594 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00557505 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00551788 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00550977 |
| VLDLR | very low density lipoprotein receptor | -0.00549666 |
| FSCN1 | fascin actin-bundling protein 1 | -0.00549209 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00549093 |
| XPO7 | exportin 7 | -0.00548938 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00545035 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00544835 |
| WWC3 | WWC family member 3 | -0.00542994 |
| PLXNA2 | plexin A2 | -0.00542667 |
| CBX5 | chromobox homolog 5 | -0.00542504 |
| ASS1 | argininosuccinate synthase 1 | -0.00541977 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00541638 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00541094 |
| GAB2 | GRB2-associated binding protein 2 | -0.00539121 |
| SEC61G | Sec61 gamma subunit | -0.00539087 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase | -0.00537451 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00536478 |
| TLN2 | talin 2 | -0.0053543 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00532583 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.00532413 |
| IL2RG | interleukin 2 receptor, gamma | -0.00531317 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0053108 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | -0.00529741 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00529545 |
| LOX | lysyl oxidase | -0.00525694 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | -0.00522036 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00521962 |
| TUBA4A | tubulin, alpha 4a | -0.00521822 |
| PRTN3 | proteinase 3 | -0.00517329 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00516985 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00515928 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00514529 |
| TAOK3 | TAO kinase 3 | -0.00514376 |
| OLFM1 | olfactomedin 1 | -0.00514111 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00513565 |
| PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | -0.00512807 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.00512721 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00512286 |
| RBM15 | RNA binding motif protein 15 | -0.00512208 |
| PGBD5 | piggyBac transposable element derived 5 | -0.00512099 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00509868 |
| RGS4 | regulator of G-protein signaling 4 | -0.00509391 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00508969 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.00508892 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.00508782 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00508747 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00506439 |
| RPH3A | rabphilin 3A | -0.00506183 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.00504655 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00503148 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00503079 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.00502633 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 | -0.00500732 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00500377 |
| CD96 | CD96 molecule | -0.00500133 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00500078 |
| ZNF331 | zinc finger protein 331 | -0.00499269 |
| PTN | pleiotrophin | -0.00499146 |
| PNN | pinin, desmosome associated protein | -0.00498708 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00497324 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -0.00496359 |
| FHL2 | four and a half LIM domains 2 | -0.00494616 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00494144 |
| FGF14 | fibroblast growth factor 14 | -0.00493965 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00493825 |
| GDF3 | growth differentiation factor 3 | -0.00493763 |
| DYSF | dysferlin | -0.00492366 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00491681 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00491606 |
| ABHD6 | abhydrolase domain containing 6 | -0.00489106 |
| TPX2 | TPX2, microtubule-associated | -0.00488466 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.00488249 |
| PAK1IP1 | PAK1 interacting protein 1 | -0.00487942 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) | -0.004877 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | -0.00485142 |
| RANBP6 | RAN binding protein 6 | -0.00484825 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -0.00484024 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.00483902 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00483495 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00482977 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.0048297 |
