PIK3CA Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha|Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5290)
External Link http://www.ncbi.nlm.nih.gov/gene/5290
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Genes

8 interacting proteins for PIK3CA from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
CCDC25 coiled-coil domain containing 25 0.631978
CLCF1 cardiotrophin-like cytokine factor 1 0.55472
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.429871
RAD51 RAD51 recombinase 0.380992
RAB37 RAB37, member RAS oncogene family 0.320702
FRMPD3 FERM and PDZ domain containing 3 0.180354
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.15557
PYCRL pyrroline-5-carboxylate reductase-like 0.042554