PIK3CA Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha|Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5290)
External Link http://www.ncbi.nlm.nih.gov/gene/5290
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Genes

4 substrates of the kinase PIK3CA from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
TPM1 tropomyosin 1 (alpha)