PIK3CD Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta|Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5293)
External Link https://ncbi.nlm.nih.gov/gene/5293
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Genes

499 genes differentially expressed following the PIK3CD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SPRED2 sprouty-related, EVH1 domain containing 2 0.0176017
CDC20 cell division cycle 20 0.0156206
MT1X metallothionein 1X 0.0130583
MT1G metallothionein 1G 0.0109236
MT1H metallothionein 1H 0.0105807
MT1E metallothionein 1E 0.00990827
PRKCA protein kinase C, alpha 0.00983426
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00963941
MT1HL1 metallothionein 1H-like 1 0.00935699
CXCL13 chemokine (C-X-C motif) ligand 13 0.00864142
TXLNA taxilin alpha 0.00853588
RRBP1 ribosome binding protein 1 0.00852429
MT1F metallothionein 1F 0.00845862
XPO7 exportin 7 0.00824078
MT2A metallothionein 2A 0.00820873
STXBP2 syntaxin binding protein 2 0.00796643
SFRP1 secreted frizzled-related protein 1 0.00796159
TFPI2 tissue factor pathway inhibitor 2 0.00785589
PNMA2 paraneoplastic Ma antigen 2 0.00751587
IGFBP6 insulin-like growth factor binding protein 6 0.00749256
SCG5 secretogranin V 0.00745698
RCAN1 regulator of calcineurin 1 0.00744593
RNF167 ring finger protein 167 0.00731091
TNS3 tensin 3 0.00721166
NAV2 neuron navigator 2 0.00709904
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.0070085
PDE8B phosphodiesterase 8B 0.0069257
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00688853
IGFBP5 insulin-like growth factor binding protein 5 0.00684369
COCH cochlin 0.00683934
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00679221
NEFH neurofilament, heavy polypeptide 0.0066447
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00661323
MAOA monoamine oxidase A 0.00659089
FKBP11 FK506 binding protein 11, 19 kDa 0.00658595
ABAT 4-aminobutyrate aminotransferase 0.0065686
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00655198
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00651306
MT1M metallothionein 1M 0.00650281
CCL19 chemokine (C-C motif) ligand 19 0.00648111
SSBP2 single-stranded DNA binding protein 2 0.00647862
POU2AF1 POU class 2 associating factor 1 0.00641337
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00637152
OLFM4 olfactomedin 4 0.00636368
CST3 cystatin C 0.00611503
JCHAIN joining chain of multimeric IgA and IgM 0.00609918
PTCH1 patched 1 0.00607584
STK32B serine/threonine kinase 32B 0.0060691
HSPB1 heat shock 27kDa protein 1 0.00606031
KANK2 KN motif and ankyrin repeat domains 2 0.00605201
SNAP25 synaptosomal-associated protein, 25kDa 0.00604977
KDM5D lysine (K)-specific demethylase 5D 0.00601572
PEG3 paternally expressed 3 0.00600363
DLK1 delta-like 1 homolog (Drosophila) 0.00596948
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00593175
MAGED1 melanoma antigen family D1 0.00591349
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00590371
BTG2 BTG family, member 2 0.00588024
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00587215
CTPS1 CTP synthase 1 0.00586617
WDR7 WD repeat domain 7 0.00582512
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00580055
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.0057937
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00578752
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.0057592
MAOB monoamine oxidase B 0.00575619
ADCY9 adenylate cyclase 9 0.00573421
WWOX WW domain containing oxidoreductase 0.00572316
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00568199
NEFM neurofilament, medium polypeptide 0.00566846
CXCR4 chemokine (C-X-C motif) receptor 4 0.0056464
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00563499
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00562924
SOBP sine oculis binding protein homolog (Drosophila) 0.00562051
SND1 staphylococcal nuclease and tudor domain containing 1 0.00561827
IRS2 insulin receptor substrate 2 0.00560661
LONP2 lon peptidase 2, peroxisomal 0.0056049
TLE4 transducin-like enhancer of split 4 0.00559061
TGM2 transglutaminase 2 0.0055877
C1S complement component 1, s subcomponent 0.00558369
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00556638
PER1 period circadian clock 1 0.00554849
ATF5 activating transcription factor 5 0.00552385
PLIN2 perilipin 2 0.00549703
C1R complement component 1, r subcomponent 0.00549299
PBX1 pre-B-cell leukemia homeobox 1 0.00546949
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00546922
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00545275
CCL5 chemokine (C-C motif) ligand 5 0.00540365
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00537417
TNIK TRAF2 and NCK interacting kinase 0.00535369
CHGB chromogranin B 0.00530042
RNF144A ring finger protein 144A 0.00530037
CXCL5 chemokine (C-X-C motif) ligand 5 0.00529115
DIPK1A divergent protein kinase domain 1A 0.00528829
MINK1 misshapen-like kinase 1 0.00528808
BCHE butyrylcholinesterase 0.00528538
COL9A2 collagen, type IX, alpha 2 0.00528267
DDB2 damage-specific DNA binding protein 2, 48kDa 0.00528141
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00528106
CRABP1 cellular retinoic acid binding protein 1 0.005262
SRPX sushi-repeat containing protein, X-linked 0.00523069
TBC1D4 TBC1 domain family, member 4 0.00521439
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.00518807
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00514607
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00514484
SETBP1 SET binding protein 1 0.00514424
RBKS ribokinase 0.00514319
BABAM2 BRISC and BRCA1 A complex member 2 0.00511951
PRKCQ protein kinase C, theta 0.00511946
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.0051165
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.00509815
TSPAN7 tetraspanin 7 0.00509051
SOCS1 suppressor of cytokine signaling 1 0.00508801
FOSL2 FOS-like antigen 2 0.00504667
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.00501287
MZB1 marginal zone B and B1 cell-specific protein 0.00501102
BTN3A2 butyrophilin, subfamily 3, member A2 0.00501016
IGFBP4 insulin-like growth factor binding protein 4 0.00500383
CSRP1 cysteine and glycine-rich protein 1 0.00498576
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.0049827
EMP3 epithelial membrane protein 3 0.00492181
NF2 neurofibromin 2 (merlin) 0.00490656
PRUNE2 prune homolog 2 (Drosophila) 0.00490289
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.0048883
PNMA8A PNMA family member 8A 0.00487564
PLCB4 phospholipase C, beta 4 0.00484905
MAVS mitochondrial antiviral signaling protein 0.00483697
NPY neuropeptide Y 0.00483589
EIF4B eukaryotic translation initiation factor 4B 0.00483052
PYGB phosphorylase, glycogen; brain 0.00480771
TM9SF3 transmembrane 9 superfamily member 3 0.00478705
PEG10 paternally expressed 10 0.0047809
KLF9 Kruppel-like factor 9 0.00477685
CAPRIN2 caprin family member 2 0.00477147
TUBB2B tubulin, beta 2B class IIb 0.00476848
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00476146
WDR45 WD repeat domain 45 0.0047519
TSPAN4 tetraspanin 4 0.0047502
SYNE1 spectrin repeat containing, nuclear envelope 1 0.00474883
WDR13 WD repeat domain 13 0.00474179
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00473661
FKBP10 FK506 binding protein 10, 65 kDa 0.00473304
ZC3H4 zinc finger CCCH-type containing 4 0.00469842
ADRB2 adrenoceptor beta 2, surface 0.00469752
EPHB2 EPH receptor B2 0.00469498
ZFP36L2 ZFP36 ring finger protein-like 2 0.00469126
TADA2A transcriptional adaptor 2A 0.00468024
MYT1L myelin transcription factor 1-like 0.00467919
TSPYL2 TSPY-like 2 0.00467777
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.0046707
CD3D CD3d molecule, delta (CD3-TCR complex) 0.00465598
ZNF91 zinc finger protein 91 0.00465463
SMAD2 SMAD family member 2 0.00462838
NUCB1 nucleobindin 1 0.0046147
SYT1 synaptotagmin I 0.00461334
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00460892
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00456791
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00456693
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00454802
BCL2L1 BCL2-like 1 0.00454425
RETREG3 reticulophagy regulator family member 3 0.00454384
HDLBP high density lipoprotein binding protein 0.00452532
WT1 Wilms tumor 1 0.00452022
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.00451977
PDE10A phosphodiesterase 10A 0.0045166
TRIM28 tripartite motif containing 28 0.00451281
ZBTB16 zinc finger and BTB domain containing 16 0.00449859
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.00449305
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.00448835
TBL1X transducin (beta)-like 1X-linked 0.0044862
CTSE cathepsin E 0.00448492
TSPYL5 TSPY-like 5 0.00448429
FUCA1 fucosidase, alpha-L- 1, tissue 0.00448313
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00447382
NID1 nidogen 1 0.00447113
SH3GL2 SH3-domain GRB2-like 2 0.0044652
ITGAV integrin, alpha V 0.00445777
IL2RG interleukin 2 receptor, gamma 0.00445598
DCAF11 DDB1 and CUL4 associated factor 11 0.00445282
NANS N-acetylneuraminic acid synthase 0.00445052
AMPD2 adenosine monophosphate deaminase 2 0.00444581
ICAM2 intercellular adhesion molecule 2 0.00444128
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00444046
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 0.00443992
GJA1 gap junction protein, alpha 1, 43kDa 0.00443919
TTI1 TELO2 interacting protein 1 0.00443702
RHOB ras homolog family member B 0.004436
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00443466
SIDT2 SID1 transmembrane family, member 2 0.00443354
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00442562
PTPRA protein tyrosine phosphatase, receptor type, A 0.00440945
PLEKHA5 pleckstrin homology domain containing, family A member 5 0.00440293
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.00436893
GSDME gasdermin E 0.00435942
INTS3 integrator complex subunit 3 0.00435414
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00435322
H1-0 H1.0 linker histone 0.00435251
LAMB1 laminin, beta 1 0.00434767
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00434541
JADE1 jade family PHD finger 1 0.00434458
DDIT4 DNA-damage-inducible transcript 4 0.00432367
FAXDC2 fatty acid hydroxylase domain containing 2 0.00431547
EPAS1 endothelial PAS domain protein 1 0.00430595
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00429922
ZFP36 ZFP36 ring finger protein 0.00427214
FKBP9 FK506 binding protein 9, 63 kDa 0.00425539
TATDN2 TatD DNase domain containing 2 0.0042421
ACADVL acyl-CoA dehydrogenase, very long chain 0.00424041
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.00423136
YLPM1 YLP motif containing 1 0.00422733
TYMS thymidylate synthetase 0.00422668
HAND2-AS1 HAND2 antisense RNA 1 (head to head) 0.00421986
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00421631
BASP1 brain abundant, membrane attached signal protein 1 0.00421507
GPM6B glycoprotein M6B 0.00421438
KHSRP KH-type splicing regulatory protein 0.00421147
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00421099
TIMP4 TIMP metallopeptidase inhibitor 4 0.0042033
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00420197
COPS7A COP9 signalosome subunit 7A 0.00419943
PEF1 penta-EF-hand domain containing 1 0.00419919
GRWD1 glutamate-rich WD repeat containing 1 0.00419596
CD93 CD93 molecule 0.00418025
TAPBP TAP binding protein (tapasin) 0.00417757
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.00416711
FANCL Fanconi anemia, complementation group L 0.00416386
SF3A3 splicing factor 3a, subunit 3, 60kDa 0.00416055
CD81 CD81 molecule 0.00415399
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.00414849
GTPBP1 GTP binding protein 1 0.00414605
CHMP4A charged multivesicular body protein 4A 0.00414536
CTSB cathepsin B 0.00414529
TGFBI transforming growth factor, beta-induced, 68kDa 0.00413067
MTMR11 myotubularin related protein 11 0.0041284
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00412776
ZBTB38 zinc finger and BTB domain containing 38 0.00412045
SCMH1 sex comb on midleg homolog 1 (Drosophila) 0.0041133
SMTN smoothelin 0.00411131
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.00409874
NARS1 asparaginyl-tRNA synthetase 1 0.00409849
GPX7 glutathione peroxidase 7 0.00409135
CDC25B cell division cycle 25B 0.0040802
NBAS neuroblastoma amplified sequence 0.00405906
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00405611
TNS1 tensin 1 0.00405556
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00405331
CYRIA CYFIP related Rac1 interactor A 0.00404937
CHD8 chromodomain helicase DNA binding protein 8 0.00404874
NDRG3 NDRG family member 3 0.00403739

decreased expression

Symbol Name Standardized Value
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0134188
RGCC regulator of cell cycle -0.0132526
CLEC2B C-type lectin domain family 2, member B -0.0121367
MAP7 microtubule-associated protein 7 -0.011602
TACSTD2 tumor-associated calcium signal transducer 2 -0.0107348
ATF3 activating transcription factor 3 -0.0105866
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0100969
S100A10 S100 calcium binding protein A10 -0.00993208
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00986062
FABP4 fatty acid binding protein 4, adipocyte -0.00960183
XIC X chromosome inactivation center -0.00955378
CXADR coxsackie virus and adenovirus receptor -0.00935478
FDX1 ferredoxin 1 -0.00904824
ANXA1 annexin A1 -0.00884218
TMEM126B transmembrane protein 126B -0.00873277
COL10A1 collagen, type X, alpha 1 -0.00867341
KRT23 keratin 23, type I -0.008402
TMEM70 transmembrane protein 70 -0.00839794
MECOM MDS1 and EVI1 complex locus -0.00838627
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00835104
HOXC6 homeobox C6 -0.00816188
LY96 lymphocyte antigen 96 -0.00813378
DCK deoxycytidine kinase -0.00804043
EVI2A ecotropic viral integration site 2A -0.00796033
TXN thioredoxin -0.00784522
CA2 carbonic anhydrase II -0.00776291
TFRC transferrin receptor -0.00767831
FZD6 frizzled class receptor 6 -0.00756925
ELOC elongin C -0.00755701
H1-2 H1.2 linker histone, cluster member -0.00753275
RTN2 reticulon 2 -0.00747801
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00744907
MOB4 MOB family member 4, phocein -0.00743744
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00742445
CLIC5 chloride intracellular channel 5 -0.00737897
ANXA3 annexin A3 -0.00732742
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00723898
S100A9 S100 calcium binding protein A9 -0.00717095
GREM1 gremlin 1, DAN family BMP antagonist -0.00715975
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -0.00708067
SDC2 syndecan 2 -0.00707094
PLIN1 perilipin 1 -0.00706904
NCK1 NCK adaptor protein 1 -0.00686139
EGR2 early growth response 2 -0.00678417
CLDND1 claudin domain containing 1 -0.00674933
SCGB2A1 secretoglobin, family 2A, member 1 -0.00670111
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0066891
SPON1 spondin 1, extracellular matrix protein -0.0066686
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.00662805
SLC38A2 solute carrier family 38, member 2 -0.00660894
INHBB inhibin, beta B -0.00659386
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00657729
COMMD10 COMM domain containing 10 -0.00655897
MPC2 mitochondrial pyruvate carrier 2 -0.00655283
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00653143
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00651655
S100A2 S100 calcium binding protein A2 -0.00644404
CSRP2 cysteine and glycine-rich protein 2 -0.0063716
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00634718
SPP1 secreted phosphoprotein 1 -0.00633038
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.0063293
GET1 guided entry of tail-anchored proteins factor 1 -0.00632061
MYO1B myosin IB -0.0063198
ZNF395 zinc finger protein 395 -0.00631294
HEBP2 heme binding protein 2 -0.00630231
MMP10 matrix metallopeptidase 10 -0.00629804
CEL carboxyl ester lipase -0.00626138
ARMC1 armadillo repeat containing 1 -0.0062218
IFT57 intraflagellar transport 57 -0.00621504
ACOT13 acyl-CoA thioesterase 13 -0.00615282
PLPP2 phospholipid phosphatase 2 -0.00612025
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00610845
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.00610353
ITGA6 integrin, alpha 6 -0.00610101
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00609749
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00608862
CGRRF1 cell growth regulator with ring finger domain 1 -0.00607541
CALD1 caldesmon 1 -0.00607364
RNFT1 ring finger protein, transmembrane 1 -0.00606459
TMSB15A thymosin beta 15a -0.00602069
CFAP20 cilia and flagella associated protein 20 -0.00595102
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00594883
CREG1 cellular repressor of E1A-stimulated genes 1 -0.00592944
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00588407
TOB1 transducer of ERBB2, 1 -0.00585638
GTF2A2 general transcription factor IIA, 2, 12kDa -0.00585217
TRAM1 translocation associated membrane protein 1 -0.00581205
MTX2 metaxin 2 -0.0058049
EMP1 epithelial membrane protein 1 -0.00579734
CST6 cystatin E/M -0.00575843
SEPTIN10 septin 10 -0.00574202
MAPK6 mitogen-activated protein kinase 6 -0.00571268
PTS 6-pyruvoyltetrahydropterin synthase -0.00570956
PKP2 plakophilin 2 -0.00570887
ADM adrenomedullin -0.00570218
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00568993
FST follistatin -0.00568126
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00565901
PPA1 pyrophosphatase (inorganic) 1 -0.0056142
COL1A2 collagen, type I, alpha 2 -0.00561074
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00560783
COMP cartilage oligomeric matrix protein -0.00559312
TMPRSS4 transmembrane protease, serine 4 -0.00557343
BHLHE41 basic helix-loop-helix family, member e41 -0.00556794
G0S2 G0/G1 switch 2 -0.00555798
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -0.00554266
LYPLA1 lysophospholipase I -0.00553717
KRT13 keratin 13, type I -0.00552907
ASNSD1 asparagine synthetase domain containing 1 -0.00551063
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -0.00551027
HSPE1 heat shock 10kDa protein 1 -0.00550741
TFDP1 transcription factor Dp-1 -0.00548473
CSTA cystatin A (stefin A) -0.00548441
RPA3 replication protein A3, 14kDa -0.00547874
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00546657
STX3 syntaxin 3 -0.00546433
PLAAT3 phospholipase A and acyltransferase 3 -0.00545092
KRT19 keratin 19, type I -0.00543799
CYB5R4 cytochrome b5 reductase 4 -0.005426
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00540977
FBXL12 F-box and leucine-rich repeat protein 12 -0.00540792
MPZL2 myelin protein zero-like 2 -0.00539176
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00538604
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -0.00538472
RAB4A RAB4A, member RAS oncogene family -0.0053841
RAB9A RAB9A, member RAS oncogene family -0.00538268
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.00537633
PTN pleiotrophin -0.00537429
TMEM14A transmembrane protein 14A -0.00537221
TPD52 tumor protein D52 -0.00536999
CRYZ crystallin, zeta (quinone reductase) -0.00535607
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -0.00535
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -0.00534062
PERP PERP, TP53 apoptosis effector -0.00532421
ASF1A anti-silencing function 1A histone chaperone -0.00529747
RIDA reactive intermediate imine deaminase A homolog -0.0052953
CD36 CD36 molecule (thrombospondin receptor) -0.00527469
PODXL podocalyxin-like -0.00525989
TAGLN2 transgelin 2 -0.00525717
ENY2 enhancer of yellow 2 homolog (Drosophila) -0.00525285
TSPAN1 tetraspanin 1 -0.00525214
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00524232
RSL24D1 ribosomal L24 domain containing 1 -0.00524034
CCN2 cellular communication network factor 2 -0.00518041
WSB1 WD repeat and SOCS box containing 1 -0.00517874
KLK7 kallikrein-related peptidase 7 -0.00517043
NDUFA4 NDUFA4, mitochondrial complex associated -0.00516985
LRRC15 leucine rich repeat containing 15 -0.00516027
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -0.00515559
SCARB2 scavenger receptor class B, member 2 -0.0051516
HIST1H2BH histone cluster 1, H2bh -0.00514238
PCSK6 proprotein convertase subtilisin/kexin type 6 -0.00514005
ATP5F1C ATP synthase F1 subunit gamma -0.00513995
CHMP5 charged multivesicular body protein 5 -0.00513567
HK2 hexokinase 2 -0.00511208
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00509959
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -0.00509684
MDFIC MyoD family inhibitor domain containing -0.00509316
SLPI secretory leukocyte peptidase inhibitor -0.00506804
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 -0.0050614
HAT1 histone acetyltransferase 1 -0.00504799
SLC38A6 solute carrier family 38, member 6 -0.00503751
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -0.00503604
ESRP1 epithelial splicing regulatory protein 1 -0.00503223
WLS wntless Wnt ligand secretion mediator -0.00501721
SAR1B secretion associated, Ras related GTPase 1B -0.0050152
LIMCH1 LIM and calponin homology domains 1 -0.00500413
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -0.00500394
ERBIN erbb2 interacting protein -0.00499909
CALML3 calmodulin-like 3 -0.00499428
GLT8D2 glycosyltransferase 8 domain containing 2 -0.00499214
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -0.00498206
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.00495922
SKAP2 src kinase associated phosphoprotein 2 -0.00495815
SRSF10 serine/arginine-rich splicing factor 10 -0.00495518
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 -0.00495024
FOLR1 folate receptor 1 (adult) -0.00494986
STX7 syntaxin 7 -0.00493652
METTL5 methyltransferase like 5 -0.00492388
MRPS28 mitochondrial ribosomal protein S28 -0.004922
RAB25 RAB25, member RAS oncogene family -0.00489893
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00489175
COL3A1 collagen, type III, alpha 1 -0.00488963
NRBF2 nuclear receptor binding factor 2 -0.00487181
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00487101
GPM6A glycoprotein M6A -0.00487059
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00485989
ATP5MG ATP synthase membrane subunit g -0.00485536
TM2D1 TM2 domain containing 1 -0.00485233
HBB hemoglobin, beta -0.0048502
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00484083
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00484076
EDN1 endothelin 1 -0.00483964
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 -0.00482124
DEFB1 defensin, beta 1 -0.00481606
RAD51AP1 RAD51 associated protein 1 -0.00481369
S100A8 S100 calcium binding protein A8 -0.00481274
TM7SF2 transmembrane 7 superfamily member 2 -0.00480485
GLRX glutaredoxin (thioltransferase) -0.00478208
PLAU plasminogen activator, urokinase -0.00478184
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00477611
CREB1 cAMP responsive element binding protein 1 -0.00477404
CALML5 calmodulin-like 5 -0.00476698
CSTB cystatin B (stefin B) -0.00476509
GLRX3 glutaredoxin 3 -0.00476388
HIST1H2AC histone cluster 1, H2ac -0.00475738
ASPN asporin -0.00475517
C3ORF52 chromosome 3 open reading frame 52 -0.00475438
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00475204
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00475101
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -0.00474505
APOE apolipoprotein E -0.00473956
FOXG1 forkhead box G1 -0.00473718
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.00473258
HSBP1 heat shock factor binding protein 1 -0.00473186
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00472451
HINT1 histidine triad nucleotide binding protein 1 -0.0047156
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00471305
CD48 CD48 molecule -0.00470905
CCNA2 cyclin A2 -0.00470501
SC5D sterol-C5-desaturase -0.004698
TYROBP TYRO protein tyrosine kinase binding protein -0.00469626
COMMD8 COMM domain containing 8 -0.0046959
HOXB7 homeobox B7 -0.00469528
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -0.00468778
TBCA tubulin folding cofactor A -0.00468132
CASP4 caspase 4, apoptosis-related cysteine peptidase -0.00466484
FOXC1 forkhead box C1 -0.00466296
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -0.00466144
TSPAN6 tetraspanin 6 -0.00465401
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00463933
PAWR PRKC, apoptosis, WT1, regulator -0.00462316
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.00461925
SGK1 serum/glucocorticoid regulated kinase 1 -0.00461836
STK17A serine/threonine kinase 17a -0.00461594
SST somatostatin -0.00461591
CRIP2 cysteine-rich protein 2 -0.00461583
HSPA4 heat shock 70kDa protein 4 -0.00461477
SPRR3 small proline-rich protein 3 -0.00461191
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.00460242
GUSBP3 glucuronidase, beta pseudogene 3 -0.00459628
KLK6 kallikrein-related peptidase 6 -0.00459469
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00458769
KLHL7 kelch-like family member 7 -0.00457923
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00454326
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0045384
LOXL1 lysyl oxidase-like 1 -0.00452632
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00451772
C21ORF91 chromosome 21 open reading frame 91 -0.00451565