| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phosphoinositide-3-kinase, regulatory subunit 5|Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 23533) |
| External Link | https://ncbi.nlm.nih.gov/gene/23533 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PIK3R5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CA2 | carbonic anhydrase II | 0.0179105 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0129846 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.012247 |
| CSTA | cystatin A (stefin A) | 0.0121689 |
| MT1E | metallothionein 1E | 0.0114703 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.01147 |
| HOPX | HOP homeobox | 0.0113875 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.0112828 |
| S100A9 | S100 calcium binding protein A9 | 0.0111925 |
| SPRR1B | small proline-rich protein 1B | 0.0103978 |
| CA12 | carbonic anhydrase XII | 0.00968229 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00964702 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00938488 |
| PITX3 | paired-like homeodomain 3 | 0.00933044 |
| LTF | lactotransferrin | 0.00922223 |
| DCK | deoxycytidine kinase | 0.00906139 |
| S100A7 | S100 calcium binding protein A7 | 0.00888434 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00857291 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00854538 |
| EMX2 | empty spiracles homeobox 2 | 0.00847252 |
| KRT6B | keratin 6B, type II | 0.00839061 |
| MT1G | metallothionein 1G | 0.00827164 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00822451 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00804185 |
| CD52 | CD52 molecule | 0.00798338 |
| MT1H | metallothionein 1H | 0.00792224 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00790222 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00784286 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00767004 |
| GAL | galanin/GMAP prepropeptide | 0.00761445 |
| SMAGP | small cell adhesion glycoprotein | 0.00761357 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00761194 |
| SPRR1A | small proline-rich protein 1A | 0.00755292 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0075465 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00739608 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00735353 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00730602 |
| SORBS3 | sorbin and SH3 domain containing 3 | 0.00728227 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00727117 |
| SELL | selectin L | 0.00718151 |
| NRN1 | neuritin 1 | 0.00714988 |
| NNMT | nicotinamide N-methyltransferase | 0.00713436 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00712458 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0071071 |
| TMEM176B | transmembrane protein 176B | 0.0070636 |
| OPN3 | opsin 3 | 0.00702489 |
| SPRR2B | small proline-rich protein 2B | 0.00702274 |
| CHPT1 | choline phosphotransferase 1 | 0.00697685 |
| S100A14 | S100 calcium binding protein A14 | 0.00691923 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.00688357 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00686981 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00678649 |
| KRT6A | keratin 6A, type II | 0.00675298 |
| TEX30 | testis expressed 30 | 0.00656019 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00654879 |
| CENPE | centromere protein E, 312kDa | 0.00649448 |
| DAPK1 | death-associated protein kinase 1 | 0.006487 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00646576 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00643827 |
| TMEM176A | transmembrane protein 176A | 0.00642045 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00640154 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00639513 |
| DNTT | DNA nucleotidylexotransferase | 0.00630956 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00630303 |
| S100A8 | S100 calcium binding protein A8 | 0.00629876 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00627774 |
| KLK5 | kallikrein-related peptidase 5 | 0.00625913 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00623897 |
| TNC | tenascin C | 0.0062336 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.00622904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00618879 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00618466 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00617153 |
| DSG3 | desmoglein 3 | 0.00615813 |
| RHOH | ras homolog family member H | 0.00615578 |
| DEFB1 | defensin, beta 1 | 0.00614032 |
| MFAP5 | microfibrillar associated protein 5 | 0.00612306 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00606914 |
| OIP5 | Opa interacting protein 5 | 0.00605861 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 | 0.00605248 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00601446 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.0059353 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00593216 |
| CLCA2 | chloride channel accessory 2 | 0.00592341 |
| CTSG | cathepsin G | 0.0059217 |
| WDR61 | WD repeat domain 61 | 0.00583629 |
| CDC42 | cell division cycle 42 | 0.00582728 |
| TCTA | T-cell leukemia translocation altered | 0.0058225 |
| KRT5 | keratin 5, type II | 0.00581211 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00580305 |
| NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 0.00578773 |
| BID | BH3 interacting domain death agonist | 0.00577501 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00576066 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00573687 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00572815 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00572539 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00570826 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00569515 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00568934 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00566117 |
| CLDN7 | claudin 7 | 0.00561537 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00561024 |
| ELANE | elastase, neutrophil expressed | 0.0055935 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00559134 |
| FST | follistatin | 0.00558215 |
| RAB38 | RAB38, member RAS oncogene family | 0.00557501 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00557202 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.00556624 |
| ACVR1B | activin A receptor, type IB | 0.0055657 |
| CLIC2 | chloride intracellular channel 2 | 0.00556274 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.00554845 |
| RPA3 | replication protein A3, 14kDa | 0.00553832 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00553533 |
| PDZK1 | PDZ domain containing 1 | 0.00553468 |
| CYBRD1 | cytochrome b reductase 1 | 0.00551446 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00548445 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00547009 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00544373 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00542283 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00541982 |
| ELP5 | elongator acetyltransferase complex subunit 5 | 0.00535284 |
| SRI | sorcin | 0.00533639 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00531351 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00529199 |
| PLK1 | polo-like kinase 1 | 0.00527012 |
| E2F8 | E2F transcription factor 8 | 0.00524412 |
| FAM3C | family with sequence similarity 3, member C | 0.00523133 |
| CRCT1 | cysteine-rich C-terminal 1 | 0.00522284 |
| TPX2 | TPX2, microtubule-associated | 0.00521772 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00521166 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.0052032 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00519267 |
| CERS6 | ceramide synthase 6 | 0.0051627 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00516232 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00514382 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | 0.00514363 |
| CYCS | cytochrome c, somatic | 0.00512566 |
| PLPBP | pyridoxal phosphate binding protein | 0.00512243 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00512156 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00509767 |
| CLDN10 | claudin 10 | 0.00508595 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00508317 |
| CCNC | cyclin C | 0.0050741 |
| DHFR | dihydrofolate reductase | 0.00506024 |
| GLRX5 | glutaredoxin 5 | 0.00505702 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | 0.00503371 |
| PCLAF | PCNA clamp associated factor | 0.00502364 |
| KLK7 | kallikrein-related peptidase 7 | 0.00501714 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00500723 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00499503 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00499489 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00499161 |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 0.00498362 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00497085 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00496549 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00496299 |
| STMN1 | stathmin 1 | 0.00495345 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00495225 |
| ATP5G1 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) | 0.00493715 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.00493633 |
| EPHA1 | EPH receptor A1 | 0.00493605 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00493195 |
| ATG5 | autophagy related 5 | 0.00492143 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | 0.00491987 |
| TAGLN2 | transgelin 2 | 0.00491133 |
| FOXG1 | forkhead box G1 | 0.00491053 |
| MUC1 | mucin 1, cell surface associated | 0.00491032 |
| HMGB3 | high mobility group box 3 | 0.00490457 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00490269 |
| TMPO | thymopoietin | 0.00489966 |
| BLNK | B-cell linker | 0.00488592 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00487204 |
| MUC4 | mucin 4, cell surface associated | 0.00487089 |
| IRF6 | interferon regulatory factor 6 | 0.00486161 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00485524 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00485457 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00484771 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.00484707 |
| STEAP1B | STEAP family member 1B | 0.00484634 |
| EDN3 | endothelin 3 | 0.0048408 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00482972 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00481567 |
| PFDN5 | prefoldin subunit 5 | 0.00481372 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00481217 |
| FOXM1 | forkhead box M1 | 0.00480475 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00479993 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0047961 |
| LMNB2 | lamin B2 | 0.00478998 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | 0.00476957 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00475843 |
| TOR1A | torsin family 1, member A (torsin A) | 0.00475777 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00471794 |
| ZG16 | zymogen granule protein 16 | 0.00471354 |
| NTS | neurotensin | 0.00469963 |
| TFDP1 | transcription factor Dp-1 | 0.00469687 |
| GMFB | glia maturation factor, beta | 0.00469549 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.00469399 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00469201 |
| DSC2 | desmocollin 2 | 0.00468852 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00467979 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00467328 |
| MRPL16 | mitochondrial ribosomal protein L16 | 0.00466277 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00465986 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00465841 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00465711 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00465369 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00464587 |
| TLCD3A | TLC domain containing 3A | 0.00464165 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00464149 |
| KIF20A | kinesin family member 20A | 0.0046394 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 0.00463794 |
| RPL36 | ribosomal protein L36 | 0.00462766 |
| PRTN3 | proteinase 3 | 0.00462394 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00462123 |
| TFCP2L1 | transcription factor CP2-like 1 | 0.00461865 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00461141 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00461112 |
| RHOA | ras homolog family member A | 0.00461023 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00460355 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00460072 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00459037 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | 0.00458895 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.0045832 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00458107 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa | 0.00457526 |
| RAB31 | RAB31, member RAS oncogene family | 0.00456468 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0045641 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00455399 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00455043 |
| STARD7 | StAR-related lipid transfer (START) domain containing 7 | 0.00452869 |
| METTL7A | methyltransferase like 7A | 0.00452469 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.00452157 |
| ATOX1 | antioxidant 1 copper chaperone | 0.00450844 |
| RETREG1 | reticulophagy regulator 1 | 0.00450768 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00450263 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 0.00449673 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0044952 |
| FBL | fibrillarin | 0.00449262 |
| APOO | apolipoprotein O | 0.00448793 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00448487 |
| GOLM1 | golgi membrane protein 1 | 0.00447773 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00447153 |
| RPL14 | ribosomal protein L14 | 0.00446743 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.0044661 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00446553 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00446415 |
| IFT52 | intraflagellar transport 52 | 0.0044636 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00446272 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00445898 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00445768 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI6 | interferon, alpha-inducible protein 6 | -0.0145931 |
| MX1 | MX dynamin-like GTPase 1 | -0.014228 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0133078 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0127057 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0122536 |
| PCP4 | Purkinje cell protein 4 | -0.0118087 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0113868 |
| OLFM4 | olfactomedin 4 | -0.0113556 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0109391 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0107331 |
| COL15A1 | collagen, type XV, alpha 1 | -0.010581 |
| IFI44L | interferon-induced protein 44-like | -0.0103393 |
| CADM1 | cell adhesion molecule 1 | -0.0100567 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00959686 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00933243 |
| IRS1 | insulin receptor substrate 1 | -0.00918603 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00910291 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0090926 |
| PTCH1 | patched 1 | -0.0090643 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.00897229 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00894811 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00889758 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00878935 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | -0.00875801 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00866137 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00861206 |
| NEFH | neurofilament, heavy polypeptide | -0.0085508 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00847016 |
| PLAT | plasminogen activator, tissue | -0.00839054 |
| IFI44 | interferon-induced protein 44 | -0.00834117 |
| TBX3 | T-box 3 | -0.00832562 |
| MMP7 | matrix metallopeptidase 7 | -0.00829551 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00816595 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00815654 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00812639 |
| CD9 | CD9 molecule | -0.00803377 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.00795616 |
| XAF1 | XIAP associated factor 1 | -0.0078479 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00782603 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0078139 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00773453 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00770468 |
| EPHB2 | EPH receptor B2 | -0.00757492 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00756487 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0075642 |
| AGR2 | anterior gradient 2 | -0.00754991 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00751176 |
| MX2 | MX dynamin-like GTPase 2 | -0.00739096 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00734589 |
| KYNU | kynureninase | -0.00727777 |
| CHMP4A | charged multivesicular body protein 4A | -0.00724674 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00723388 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0072194 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00721792 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00711361 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00710971 |
| EGR1 | early growth response 1 | -0.00709837 |
| BTG2 | BTG family, member 2 | -0.00709146 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00704682 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00702368 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00701881 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00700635 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00700055 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00693789 |
| BBX | bobby sox homolog (Drosophila) | -0.00692661 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00690631 |
| SYNM | synemin, intermediate filament protein | -0.00690062 |
| MEIS2 | Meis homeobox 2 | -0.0068928 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00689144 |
| BMP4 | bone morphogenetic protein 4 | -0.00687503 |
| APOD | apolipoprotein D | -0.00685301 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00684877 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00683861 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 | -0.00682138 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00681857 |
| PLCB4 | phospholipase C, beta 4 | -0.00680893 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00674962 |
| CLGN | calmegin | -0.0067373 |
| MTF2 | metal response element binding transcription factor 2 | -0.00668998 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00666761 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0066586 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00665386 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.00662669 |
| RGS16 | regulator of G-protein signaling 16 | -0.00661462 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00660788 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | -0.00660215 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00656842 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00652627 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00647895 |
| L1CAM | L1 cell adhesion molecule | -0.00647649 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0064549 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00640531 |
| MATN2 | matrilin 2 | -0.00639467 |
| MECOM | MDS1 and EVI1 complex locus | -0.00639041 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00634661 |
| GNAS | GNAS complex locus | -0.00631559 |
| G0S2 | G0/G1 switch 2 | -0.0063038 |
| PENK | proenkephalin | -0.00629023 |
| PDE10A | phosphodiesterase 10A | -0.00627985 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00626465 |
| SVIL | supervillin | -0.00623192 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0062303 |
| LOXL2 | lysyl oxidase-like 2 | -0.0062137 |
| S100A4 | S100 calcium binding protein A4 | -0.00620967 |
| KMT5B | lysine methyltransferase 5B | -0.00620819 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00620021 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00619453 |
| MGP | matrix Gla protein | -0.00618466 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00617766 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00617402 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00615458 |
| PHIP | pleckstrin homology domain interacting protein | -0.00615052 |
| LAMB1 | laminin, beta 1 | -0.00610127 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00609862 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00608557 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00608048 |
| WWC3 | WWC family member 3 | -0.00606034 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0060496 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00604117 |
| DACH1 | dachshund family transcription factor 1 | -0.00602048 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00601054 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0060085 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00600212 |
| LBH | limb bud and heart development | -0.00597396 |
| TNNC1 | troponin C type 1 (slow) | -0.00595886 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00595394 |
| ARG2 | arginase 2 | -0.00594733 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.0059429 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.00592709 |
| MEIS1 | Meis homeobox 1 | -0.00592073 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.00590153 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00589858 |
| FOXF1 | forkhead box F1 | -0.0058631 |
| TNS3 | tensin 3 | -0.00585916 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | -0.00585484 |
| STAG2 | stromal antigen 2 | -0.00585288 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00582425 |
| A2M | alpha-2-macroglobulin | -0.00582371 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0058154 |
| GPX2 | glutathione peroxidase 2 | -0.00579773 |
| PFN2 | profilin 2 | -0.00578051 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.00578011 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00576856 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00575587 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00575131 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00575101 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.00574854 |
| KRT23 | keratin 23, type I | -0.00571488 |
| RRBP1 | ribosome binding protein 1 | -0.00570954 |
| CCN3 | cellular communication network factor 3 | -0.00570431 |
| HMOX1 | heme oxygenase 1 | -0.00570133 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00568069 |
| MITF | microphthalmia-associated transcription factor | -0.00567486 |
| SETBP1 | SET binding protein 1 | -0.00566865 |
| AGRN | agrin | -0.00566859 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00566775 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00566694 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00566045 |
| ITGAV | integrin, alpha V | -0.00565968 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00564755 |
| S100A11 | S100 calcium binding protein A11 | -0.00563121 |
| GPATCH8 | G patch domain containing 8 | -0.00562157 |
| CAPRIN2 | caprin family member 2 | -0.00561469 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.00560297 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00559892 |
| KLK2 | kallikrein-related peptidase 2 | -0.00559426 |
| PLK2 | polo-like kinase 2 | -0.00559024 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00558816 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00557327 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00557289 |
| SERINC5 | serine incorporator 5 | -0.00556929 |
| SP100 | SP100 nuclear antigen | -0.00556371 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00555908 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00554645 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00552806 |
| TAC1 | tachykinin, precursor 1 | -0.0055067 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00548798 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00547925 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00546895 |
| FZD2 | frizzled class receptor 2 | -0.00546319 |
| VGLL4 | vestigial-like family member 4 | -0.00545932 |
| IL6 | interleukin 6 | -0.00545638 |
| PLN | phospholamban | -0.00544477 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00543707 |
| NBEA | neurobeachin | -0.00543116 |
| SCG5 | secretogranin V | -0.0054298 |
| TRIB1 | tribbles pseudokinase 1 | -0.00542029 |
| KLK11 | kallikrein-related peptidase 11 | -0.00540518 |
| ZNF532 | zinc finger protein 532 | -0.00540482 |
| VLDLR | very low density lipoprotein receptor | -0.00539938 |
| IL7R | interleukin 7 receptor | -0.00539906 |
| PEG10 | paternally expressed 10 | -0.00539689 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00538081 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.0053565 |
| SMAD3 | SMAD family member 3 | -0.00535544 |
| ANXA3 | annexin A3 | -0.00535333 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00534075 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00533508 |
| PDGFC | platelet derived growth factor C | -0.00532808 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.00531978 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.00529859 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.00529532 |
| PEG3 | paternally expressed 3 | -0.00528563 |
| FAM13B | family with sequence similarity 13, member B | -0.00527387 |
| RNF43 | ring finger protein 43 | -0.00527201 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00527178 |
| KLK3 | kallikrein-related peptidase 3 | -0.00526769 |
| NKX3-1 | NK3 homeobox 1 | -0.00524897 |
| TES | testin LIM domain protein | -0.0052478 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00524709 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0052449 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00524433 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.00524263 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00522736 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00521753 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00520227 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00519441 |
| RBPMS | RNA binding protein with multiple splicing | -0.00519248 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00518287 |
| COL4A1 | collagen, type IV, alpha 1 | -0.00518259 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00516061 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00515238 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00514924 |
| MCAM | melanoma cell adhesion molecule | -0.00514432 |
| KLHL21 | kelch-like family member 21 | -0.00514022 |
| THAP11 | THAP domain containing 11 | -0.00513861 |
| ZNF160 | zinc finger protein 160 | -0.00512433 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00512335 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00511258 |
| LAMA5 | laminin, alpha 5 | -0.00510821 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0050953 |
| ZNF654 | zinc finger protein 654 | -0.00508675 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00508669 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00508607 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00507827 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00506446 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific | -0.00506136 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00506091 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00505356 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00503288 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00502182 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00501617 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | -0.00501579 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00500397 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00499263 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00498669 |
| RIN2 | Ras and Rab interactor 2 | -0.00496843 |
| EFNB2 | ephrin-B2 | -0.00495666 |
| FRZB | frizzled-related protein | -0.0049558 |
| E2F3 | E2F transcription factor 3 | -0.0049438 |
