PINK1 Gene Set

Dataset Kinase Library Tyrosine Kinome Atlas
Category proteomics
Type kinase
Description PTEN induced putative kinase 1|This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 65018)
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100 substrates of the kinase PINK1 from the Kinase Library Tyrosine Kinome Atlas dataset.

Symbol Name Standardized Value
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 100.0
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) 99.89
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 99.87
TBC1D3C TBC1 domain family, member 3C 99.85
FZD2 frizzled class receptor 2 99.8
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 99.8
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 99.8
CKMT1B creatine kinase, mitochondrial 1B 99.72
TENM3 teneurin transmembrane protein 3 99.71
SLC44A2 solute carrier family 44 (choline transporter), member 2 99.67
SRSF10 serine/arginine-rich splicing factor 10 99.67
LHX3 LIM homeobox 3 99.63
MIS18BP1 MIS18 binding protein 1 99.63
SLC4A2 solute carrier family 4 (anion exchanger), member 2 99.61
ZNF579 zinc finger protein 579 99.58
RBM25 RNA binding motif protein 25 99.52
CADM1 cell adhesion molecule 1 99.39
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 99.36
YBX3 Y box binding protein 3 99.32
ADAM15 ADAM metallopeptidase domain 15 99.32
TFIP11 tuftelin interacting protein 11 99.28
HPSE heparanase 99.26
PPARD peroxisome proliferator-activated receptor delta 99.25
PINK1 PTEN induced putative kinase 1 99.23
PRDX1 peroxiredoxin 1 99.17
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 99.17
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 99.13
RPS29 ribosomal protein S29 99.1
PADI2 peptidyl arginine deiminase, type II 99.06
PTPN23 protein tyrosine phosphatase, non-receptor type 23 99.01
DMWD dystrophia myotonica, WD repeat containing 98.95
THADA thyroid adenoma associated 98.9
SRSF3 serine/arginine-rich splicing factor 3 98.88
CASQ2 calsequestrin 2 (cardiac muscle) 98.71
PFKM phosphofructokinase, muscle 98.51
SCN5A sodium channel, voltage gated, type V alpha subunit 98.5
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 98.47
TMEM132A transmembrane protein 132A 98.4
ZFPL1 zinc finger protein-like 1 98.34
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 98.31
IKZF3 IKAROS family zinc finger 3 (Aiolos) 98.27
SMG8 SMG8 nonsense mediated mRNA decay factor 98.23
MARVELD3 MARVEL domain containing 3 98.2
EGR1 early growth response 1 98.16
COX6C cytochrome c oxidase subunit VIc 98.14
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 98.09
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 98.03
AFF2 AF4/FMR2 family, member 2 97.99
SRSF7 serine/arginine-rich splicing factor 7 97.83
SCN9A sodium channel, voltage gated, type IX alpha subunit 97.74
WWP2 WW domain containing E3 ubiquitin protein ligase 2 97.74
TCHP trichoplein, keratin filament binding 97.68
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 97.66
SPANXN2 SPANX family, member N2 97.57
MMP14 matrix metallopeptidase 14 (membrane-inserted) 97.55
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 97.31
ADA adenosine deaminase 97.26
SH3GLB1 SH3-domain GRB2-like endophilin B1 97.22
SPATS2L spermatogenesis associated, serine-rich 2-like 97.2
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 97.18
EPM2AIP1 EPM2A (laforin) interacting protein 1 97.16
RBX1 ring-box 1, E3 ubiquitin protein ligase 97.16
PTTG1IP pituitary tumor-transforming 1 interacting protein 97.155
MRPS27 mitochondrial ribosomal protein S27 97.15
HIP1 huntingtin interacting protein 1 97.09
CLK2 CDC-like kinase 2 97.07
FCHO1 FCH domain only 1 97.05
SLA2 Src-like-adaptor 2 97.04
IGF1R insulin-like growth factor 1 receptor 97.0
ACOT7 acyl-CoA thioesterase 7 96.98
KATNB1 katanin p80 (WD repeat containing) subunit B 1 96.93
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 96.85
SCRIB scribbled planar cell polarity protein 96.785
EDC3 enhancer of mRNA decapping 3 96.59
MXRA5 matrix-remodelling associated 5 96.56
SH3GLB2 SH3-domain GRB2-like endophilin B2 96.48
RFTN1 raftlin, lipid raft linker 1 96.46
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 96.43
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 96.37
GOPC golgi-associated PDZ and coiled-coil motif containing 96.28
MUC16 mucin 16, cell surface associated 96.23
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 96.19
USP24 ubiquitin specific peptidase 24 96.08
LYST lysosomal trafficking regulator 96.06
FAM171A1 family with sequence similarity 171, member A1 96.04
USP43 ubiquitin specific peptidase 43 96.015
MYO1B myosin IB 96.0
CDK13 cyclin-dependent kinase 13 95.99
RDX radixin 95.88
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 95.82
GEMIN8 gem (nuclear organelle) associated protein 8 95.82
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 95.78
SLCO3A1 solute carrier organic anion transporter family, member 3A1 95.75
JPH2 junctophilin 2 95.71
S100A7 S100 calcium binding protein A7 95.64
MCC mutated in colorectal cancers 95.62
C5ORF15 chromosome 5 open reading frame 15 95.6
ARRB1 arrestin, beta 1 95.58
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 95.54
FBXO11 F-box protein 11 95.51