PINK1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description PTEN induced putative kinase 1|This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 65018)
External Link http://www.ncbi.nlm.nih.gov/gene/65018
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Genes

57 interacting proteins for PINK1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BAG2 BCL2-associated athanogene 2
BCL2L1 BCL2-like 1
BCL2L2-PABPN1 BCL2L2-PABPN1 readthrough
CDC37 cell division cycle 37
COPS8 COP9 signalosome subunit 8
CRLS1 cardiolipin synthase 1
EED embryonic ectoderm development
FBXO7 F-box protein 7
HNF4A hepatocyte nuclear factor 4, alpha
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HTRA2 HtrA serine peptidase 2
IRAK1 interleukin-1 receptor-associated kinase 1
IRS4 insulin receptor substrate 4
KIF11 kinesin family member 11
MAP1B microtubule-associated protein 1B
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MCL1 myeloid cell leukemia 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NRF1 nuclear respiratory factor 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARL presenilin associated, rhomboid-like
PGAM5 phosphoglycerate mutase family member 5
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTEN phosphatase and tensin homolog
RB1CC1 RB1-inducible coiled-coil 1
RHOT1 ras homolog family member T1
RICTOR RPTOR independent companion of MTOR, complex 2
RPS27A ribosomal protein S27a
SARM1 sterile alpha and TIR motif containing 1
SENP8 SUMO/sentrin specific peptidase family member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)
TOLLIP toll interacting protein
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAP1 TNF receptor-associated protein 1
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
UBC ubiquitin C
UBE2M ubiquitin-conjugating enzyme E2M
VIM vimentin