PIP4K2A Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description phosphatidylinositol-5-phosphate 4-kinase, type II, alpha|Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5305)
External Link https://ncbi.nlm.nih.gov/gene/5305
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Genes

497 genes differentially expressed following the PIP4K2A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0209468
PHACTR2 phosphatase and actin regulator 2 0.0164806
CADM1 cell adhesion molecule 1 0.0143361
TXNDC9 thioredoxin domain containing 9 0.0136343
SLC38A1 solute carrier family 38, member 1 0.0131749
TRPS1 trichorhinophalangeal syndrome I 0.0116338
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.0113145
TPD52L1 tumor protein D52-like 1 0.0111797
CPVL carboxypeptidase, vitellogenic-like 0.010979
GSTA1 glutathione S-transferase alpha 1 0.0106022
CST3 cystatin C 0.0105024
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0105012
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.0104616
CPE carboxypeptidase E 0.0104461
CLU clusterin 0.0101414
SDC2 syndecan 2 0.0101385
PDGFC platelet derived growth factor C 0.00992898
KRAS Kirsten rat sarcoma viral oncogene homolog 0.00987573
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00984774
NBPF10 neuroblastoma breakpoint family, member 10 0.00979853
NOTCH2 notch 2 0.00946859
PCP4 Purkinje cell protein 4 0.00926448
ALB albumin 0.00920006
NOTCH2NL notch 2 N-terminal like 0.00914363
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00913102
GREM1 gremlin 1, DAN family BMP antagonist 0.009023
CXCL14 chemokine (C-X-C motif) ligand 14 0.00902057
FRY furry homolog (Drosophila) 0.00893173
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00883841
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00881422
MIR22HG MIR22 host gene 0.00858599
XIC X chromosome inactivation center 0.00856767
ACKR3 atypical chemokine receptor 3 0.00852248
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00842338
IDO1 indoleamine 2,3-dioxygenase 1 0.00839696
NIT1 nitrilase 1 0.00834296
PAX6 paired box 6 0.00832606
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00826529
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00822996
MTCL1 microtubule crosslinking factor 1 0.00821668
COL4A5 collagen, type IV, alpha 5 0.0081592
TPBG trophoblast glycoprotein 0.00814902
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00812472
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00812417
SCG5 secretogranin V 0.00805081
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00798073
GSTM3 glutathione S-transferase mu 3 (brain) 0.00796688
SCARB2 scavenger receptor class B, member 2 0.00796181
GLIPR1 GLI pathogenesis-related 1 0.00795751
CLGN calmegin 0.00788467
ZIC1 Zic family member 1 0.00787846
KLF9 Kruppel-like factor 9 0.00783486
GLUD1 glutamate dehydrogenase 1 0.00783077
ABAT 4-aminobutyrate aminotransferase 0.00781676
APLP2 amyloid beta (A4) precursor-like protein 2 0.00781402
REV1 REV1, polymerase (DNA directed) 0.00779684
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00776317
RNPS1 RNA binding protein S1, serine-rich domain 0.00775648
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00770778
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00770551
HMGN3 high mobility group nucleosomal binding domain 3 0.00768215
TDO2 tryptophan 2,3-dioxygenase 0.0076734
CXCL11 chemokine (C-X-C motif) ligand 11 0.00763467
CHN2 chimerin 2 0.00757961
STK26 serine/threonine protein kinase 26 0.0075533
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00754386
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00750417
ARMT1 acidic residue methyltransferase 1 0.00745562
FZD6 frizzled class receptor 6 0.00743968
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 0.00740279
APOB apolipoprotein B 0.00739948
TSPAN13 tetraspanin 13 0.00739613
NIBAN1 niban apoptosis regulator 1 0.00734731
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00728799
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00727418
PRDX2 peroxiredoxin 2 0.00724375
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00720224
SORT1 sortilin 1 0.00718914
FAM13B family with sequence similarity 13, member B 0.00718703
BASP1 brain abundant, membrane attached signal protein 1 0.00717021
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00715788
VCAM1 vascular cell adhesion molecule 1 0.00712114
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0070903
FHL1 four and a half LIM domains 1 0.00708656
IFI6 interferon, alpha-inducible protein 6 0.00708398
SC5D sterol-C5-desaturase 0.0070696
LRRC17 leucine rich repeat containing 17 0.00706442
RHOBTB3 Rho-related BTB domain containing 3 0.00705572
KRT23 keratin 23, type I 0.00705453
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00705428
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00704608
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.00703236
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00698196
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00694551
KANK1 KN motif and ankyrin repeat domains 1 0.00694173
CREB1 cAMP responsive element binding protein 1 0.00693513
RNF115 ring finger protein 115 0.00691187
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00690491
MANSC1 MANSC domain containing 1 0.0068783
GLUD2 glutamate dehydrogenase 2 0.00687671
KAT2B K(lysine) acetyltransferase 2B 0.00686207
CXCL10 chemokine (C-X-C motif) ligand 10 0.00680731
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.00680203
LIPT1 lipoyltransferase 1 0.00679635
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 0.00678755
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00677791
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00675752
TPSAB1 tryptase alpha/beta 1 0.00674584
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00674484
TSPYL5 TSPY-like 5 0.00672215
HIST1H2BD histone cluster 1, H2bd 0.00671169
LRP2 low density lipoprotein receptor-related protein 2 0.00670707
RNF6 ring finger protein (C3H2C3 type) 6 0.00669265
TMED5 transmembrane emp24 protein transport domain containing 5 0.00668392
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00666558
FUCA1 fucosidase, alpha-L- 1, tissue 0.00664394
IRS1 insulin receptor substrate 1 0.0066278
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.0066093
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.00658755
ZBTB18 zinc finger and BTB domain containing 18 0.00654939
HDDC2 HD domain containing 2 0.00654844
TNC tenascin C 0.00654318
GCA grancalcin, EF-hand calcium binding protein 0.00653841
RNFT1 ring finger protein, transmembrane 1 0.00653729
FBXL5 F-box and leucine-rich repeat protein 5 0.00652848
APOA1 apolipoprotein A-I 0.00652543
CPB1 carboxypeptidase B1 (tissue) 0.00650979
MT1M metallothionein 1M 0.00650796
DLG1 discs, large homolog 1 (Drosophila) 0.0064917
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00645104
DEPTOR DEP domain containing MTOR-interacting protein 0.00634833
CXCL9 chemokine (C-X-C motif) ligand 9 0.00634729
NOVA1 neuro-oncological ventral antigen 1 0.00631852
REG3A regenerating islet-derived 3 alpha 0.00631453
RC3H2 ring finger and CCCH-type domains 2 0.00626976
GYG1 glycogenin 1 0.00624251
INTS6 integrator complex subunit 6 0.00621054
USP6NL USP6 N-terminal like 0.0062071
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00620501
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 0.00619513
AKR1C3 aldo-keto reductase family 1, member C3 0.00617997
FGF13 fibroblast growth factor 13 0.00616702
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00615129
LOX lysyl oxidase 0.0061462
DACH1 dachshund family transcription factor 1 0.00614471
PTER phosphotriesterase related 0.00614316
CRP C-reactive protein, pentraxin-related 0.00613478
HAUS3 HAUS augmin-like complex, subunit 3 0.00611276
CPD carboxypeptidase D 0.00611006
LCMT2 leucine carboxyl methyltransferase 2 0.00610781
ADCY9 adenylate cyclase 9 0.00610136
ALCAM activated leukocyte cell adhesion molecule 0.00607724
ZNF652 zinc finger protein 652 0.00606108
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.00605677
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00605636
GOLGA8A golgin A8 family, member A 0.00605198
ESR1 estrogen receptor 1 0.00602288
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 0.00601537
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00601082
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00600613
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 0.00599936
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00599738
LYZ lysozyme 0.0059801
CCL15 chemokine (C-C motif) ligand 15 0.00597091
APOC3 apolipoprotein C-III 0.0059699
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00595146
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.0059324
TASOR2 transcription activation suppressor family member 2 0.00593031
IRF9 interferon regulatory factor 9 0.00592717
TSPYL1 TSPY-like 1 0.0059245
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00591539
CCL2 chemokine (C-C motif) ligand 2 0.00590925
TULP4 tubby like protein 4 0.00589103
GPI glucose-6-phosphate isomerase 0.00588454
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00588232
ADGRL2 adhesion G protein-coupled receptor L2 0.00586301
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00581748
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.005815
EPAS1 endothelial PAS domain protein 1 0.00580749
PER3 period circadian clock 3 0.00580453
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00578023
OSMR oncostatin M receptor 0.00577982
TENT5A terminal nucleotidyltransferase 5A 0.0057723
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00576923
MAPK1 mitogen-activated protein kinase 1 0.00576552
HNMT histamine N-methyltransferase 0.00576117
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.00576057
CTSK cathepsin K 0.00575418
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00575021
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00571548
COMMD8 COMM domain containing 8 0.0056969
PENK proenkephalin 0.00569132
TMEM260 transmembrane protein 260 0.00568656
MICU2 mitochondrial calcium uptake 2 0.00567821
FNDC3A fibronectin type III domain containing 3A 0.00567756
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.00567633
CDK17 cyclin-dependent kinase 17 0.00565907
PAWR PRKC, apoptosis, WT1, regulator 0.00564894
ANKRD49 ankyrin repeat domain 49 0.00564504
TSPYL4 TSPY-like 4 0.00564122
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00564086
CFB complement factor B 0.00563582
AUTS2 autism susceptibility candidate 2 0.00562183
FBN2 fibrillin 2 0.00562133
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.00562108
ANKRD12 ankyrin repeat domain 12 0.00561951
GPR88 G protein-coupled receptor 88 0.00561703
SUCO SUN domain containing ossification factor 0.00560589
TMEM106B transmembrane protein 106B 0.00560172
PEX3 peroxisomal biogenesis factor 3 0.0055959
GOLIM4 golgi integral membrane protein 4 0.00556394
PDZK1 PDZ domain containing 1 0.00555719
GBAP1 glucosidase, beta, acid pseudogene 1 0.00553831
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00553589
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.00552939
DYNLT1 dynein, light chain, Tctex-type 1 0.00550744
QKI QKI, KH domain containing, RNA binding 0.00548221
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00548205
HHEX hematopoietically expressed homeobox 0.00547401
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00547153
ADGRA3 adhesion G protein-coupled receptor A3 0.00546528
TARDBP TAR DNA binding protein 0.00546169
CREBZF CREB/ATF bZIP transcription factor 0.00546149
NEMP1 nuclear envelope integral membrane protein 1 0.00545988
YAP1 Yes-associated protein 1 0.00545961
HIST1H2BK histone cluster 1, H2bk 0.00545683
GCH1 GTP cyclohydrolase 1 0.00545409
MN1 meningioma (disrupted in balanced translocation) 1 0.00544886
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00544877
BBX bobby sox homolog (Drosophila) 0.00544044
EFR3A EFR3 homolog A (S. cerevisiae) 0.00543474
THBD thrombomodulin 0.00542064
GPC4 glypican 4 0.00541725
C4BPB complement component 4 binding protein, beta 0.00541484
RIT1 Ras-like without CAAX 1 0.00539479
HIST1H2AE histone cluster 1, H2ae 0.00539031
PAH phenylalanine hydroxylase 0.00538589
RABGAP1L RAB GTPase activating protein 1-like 0.00538413
SESN1 sestrin 1 0.00537972
GBP1 guanylate binding protein 1, interferon-inducible 0.00537107
CPA3 carboxypeptidase A3 (mast cell) 0.00536643
MARCHF6 membrane associated ring-CH-type finger 6 0.0053639
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00535525
SEPP1 selenoprotein P, plasma, 1 0.00534797
ZSCAN16 zinc finger and SCAN domain containing 16 0.00534549
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00533972
UBP1 upstream binding protein 1 (LBP-1a) 0.0053314
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.00532477
CCL8 chemokine (C-C motif) ligand 8 0.00532153

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -0.0135588
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0126888
PCNA proliferating cell nuclear antigen -0.0124177
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.0120887
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0120679
POU2AF1 POU class 2 associating factor 1 -0.0117539
GSTP1 glutathione S-transferase pi 1 -0.011431
FCGBP Fc fragment of IgG binding protein -0.0113843
CLEC11A C-type lectin domain family 11, member A -0.0111252
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.0110526
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.0107984
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0107918
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0107865
KRT15 keratin 15, type I -0.0107732
MAGEA3 melanoma antigen family A3 -0.0107138
MZB1 marginal zone B and B1 cell-specific protein -0.010686
BAMBI BMP and activin membrane-bound inhibitor -0.0105004
MAL mal, T-cell differentiation protein -0.0104213
INAVA innate immunity activator -0.0102473
AKAP12 A kinase (PRKA) anchor protein 12 -0.010172
LAMB1 laminin, beta 1 -0.00992194
S100A7 S100 calcium binding protein A7 -0.00979782
MME membrane metallo-endopeptidase -0.00969381
ETHE1 ethylmalonic encephalopathy 1 -0.00967057
AHCY adenosylhomocysteinase -0.00963409
TUBB2A tubulin, beta 2A class IIa -0.00962865
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00957065
KLF6 Kruppel-like factor 6 -0.00930082
GPX1 glutathione peroxidase 1 -0.0091573
DIPK1A divergent protein kinase domain 1A -0.00911557
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.0091086
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.009038
FERMT1 fermitin family member 1 -0.00903419
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00884731
FSCN1 fascin actin-bundling protein 1 -0.00876207
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00869417
KRT5 keratin 5, type II -0.00856651
HSP90B2P heat shock protein 90kDa beta (Grp94), member 2, pseudogene -0.0085614
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00848574
ITM2C integral membrane protein 2C -0.00843676
JPT1 Jupiter microtubule associated homolog 1 -0.00842952
KLK10 kallikrein-related peptidase 10 -0.00841853
MTUS1 microtubule associated tumor suppressor 1 -0.00841159
GYPC glycophorin C (Gerbich blood group) -0.00841055
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00840749
TSPAN8 tetraspanin 8 -0.00837586
SLPI secretory leukocyte peptidase inhibitor -0.00835918
TFRC transferrin receptor -0.00824885
OXA1L oxidase (cytochrome c) assembly 1-like -0.00824489
MIA melanoma inhibitory activity -0.00818026
WDR61 WD repeat domain 61 -0.0081266
MCAM melanoma cell adhesion molecule -0.0080214
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00801257
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00799961
METRN meteorin, glial cell differentiation regulator -0.00799441
C10ORF10 chromosome 10 open reading frame 10 -0.0079199
RPL14 ribosomal protein L14 -0.00787997
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00782199
FXYD5 FXYD domain containing ion transport regulator 5 -0.00780133
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00774583
MSMB microseminoprotein, beta- -0.00772868
RHCG Rh family, C glycoprotein -0.0077229
A2M alpha-2-macroglobulin -0.00768408
MXRA5 matrix-remodelling associated 5 -0.0076371
RGCC regulator of cell cycle -0.0075994
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 -0.00755979
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00755072
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.0075119
HSPA8 heat shock 70kDa protein 8 -0.00750351
PUF60 poly-U binding splicing factor 60KDa -0.0074268
BGN biglycan -0.00739026
LY6D lymphocyte antigen 6 complex, locus D -0.00737658
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00737271
RAI14 retinoic acid induced 14 -0.00733658
THBS2 thrombospondin 2 -0.00731557
CD248 CD248 molecule, endosialin -0.00729081
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00726131
PLIN3 perilipin 3 -0.00725946
TXN thioredoxin -0.00725144
HOPX HOP homeobox -0.00722354
IGFBP6 insulin-like growth factor binding protein 6 -0.00720777
SRPX sushi-repeat containing protein, X-linked -0.00718799
CA12 carbonic anhydrase XII -0.00718423
LAMP3 lysosomal-associated membrane protein 3 -0.00716829
NELL2 NEL-like 2 (chicken) -0.00716408
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00714763
COG7 component of oligomeric golgi complex 7 -0.00714277
ITM2A integral membrane protein 2A -0.00714092
ZNF185 zinc finger protein 185 (LIM domain) -0.00710128
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.0070432
HSPB1 heat shock 27kDa protein 1 -0.00703644
DEFB1 defensin, beta 1 -0.00696038
CD99 CD99 molecule -0.0069519
NID1 nidogen 1 -0.00694675
ANGPT2 angiopoietin 2 -0.00694096
EFNA1 ephrin-A1 -0.00690289
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -0.00688566
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00686164
TMEM176A transmembrane protein 176A -0.00685998
LAMB3 laminin, beta 3 -0.00685596
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.00682395
AEBP1 AE binding protein 1 -0.00681815
HMGA1 high mobility group AT-hook 1 -0.0067826
IFI16 interferon, gamma-inducible protein 16 -0.00677326
HEATR1 HEAT repeat containing 1 -0.0067585
TBX2 T-box 2 -0.00675412
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00673301
KLK11 kallikrein-related peptidase 11 -0.00671574
EIF3F eukaryotic translation initiation factor 3, subunit F -0.00670672
EIF3K eukaryotic translation initiation factor 3, subunit K -0.00666808
EFNA5 ephrin-A5 -0.00666204
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.00664302
SPON2 spondin 2, extracellular matrix protein -0.00662374
AHCYL2 adenosylhomocysteinase-like 2 -0.00658863
GRB7 growth factor receptor-bound protein 7 -0.00658608
LHFP lipoma HMGIC fusion partner -0.00658587
NID2 nidogen 2 (osteonidogen) -0.00657332
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00656524
JCHAIN joining chain of multimeric IgA and IgM -0.00648938
NPM3 nucleophosmin/nucleoplasmin 3 -0.0064889
RFTN1 raftlin, lipid raft linker 1 -0.00648837
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00643104
GAS6 growth arrest-specific 6 -0.00642405
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00640921
FRZB frizzled-related protein -0.00640894
CLDN7 claudin 7 -0.00639385
LGALS9 lectin, galactoside-binding, soluble, 9 -0.00634422
NR0B1 nuclear receptor subfamily 0, group B, member 1 -0.00633092
TMEM230 transmembrane protein 230 -0.00629852
AQP3 aquaporin 3 (Gill blood group) -0.00628699
OSBPL3 oxysterol binding protein-like 3 -0.00627667
NPDC1 neural proliferation, differentiation and control, 1 -0.00625596
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -0.00625494
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00623954
FBLN2 fibulin 2 -0.00623308
TP53I3 tumor protein p53 inducible protein 3 -0.00622096
ACP5 acid phosphatase 5, tartrate resistant -0.0062101
SORBS3 sorbin and SH3 domain containing 3 -0.00620911
IGBP1 immunoglobulin (CD79A) binding protein 1 -0.00620904
MAP4 microtubule-associated protein 4 -0.00620111
COCH cochlin -0.00619249
MGP matrix Gla protein -0.0061737
YBX3 Y box binding protein 3 -0.00617164
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00615636
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00613209
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 -0.00612669
KDSR 3-ketodihydrosphingosine reductase -0.00611796
RAB25 RAB25, member RAS oncogene family -0.00611004
DHRS3 dehydrogenase/reductase (SDR family) member 3 -0.00609612
ADA adenosine deaminase -0.00608396
H1-10 H1.10 linker histone -0.00608043
IRS2 insulin receptor substrate 2 -0.00607817
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00607736
TMEM176B transmembrane protein 176B -0.00607339
PTGES prostaglandin E synthase -0.00605681
LAMA4 laminin, alpha 4 -0.00605635
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00604946
FAR2 fatty acyl CoA reductase 2 -0.00604124
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00603393
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00603088
CSNK1E casein kinase 1, epsilon -0.00602143
RPS9 ribosomal protein S9 -0.0060074
RIPK4 receptor-interacting serine-threonine kinase 4 -0.00600379
RPS14P3 ribosomal protein S14 pseudogene 3 -0.00599659
TSPO translocator protein (18kDa) -0.00599536
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00597754
DPH5 diphthamide biosynthesis 5 -0.00597285
BPHL biphenyl hydrolase-like (serine hydrolase) -0.00597143
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.00596055
ETFB electron-transfer-flavoprotein, beta polypeptide -0.00595821
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00595069
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.00593405
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00592042
TRIM28 tripartite motif containing 28 -0.00591872
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0058892
NPEPL1 aminopeptidase-like 1 -0.00588578
LETMD1 LETM1 domain containing 1 -0.00587588
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -0.0058727
SRGN serglycin -0.0058709
NCK1 NCK adaptor protein 1 -0.00586893
MYH10 myosin, heavy chain 10, non-muscle -0.00586065
NDN necdin, melanoma antigen (MAGE) family member -0.00585728
DNTT DNA nucleotidylexotransferase -0.00584787
IL2RG interleukin 2 receptor, gamma -0.00582876
MUC4 mucin 4, cell surface associated -0.00582025
CEMIP cell migration inducing protein, hyaluronan binding -0.00581088
CALML3 calmodulin-like 3 -0.00580869
CLEC2B C-type lectin domain family 2, member B -0.00579445
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00578968
TRIP10 thyroid hormone receptor interactor 10 -0.00577235
TCTA T-cell leukemia translocation altered -0.00576676
POPDC3 popeye domain containing 3 -0.00575872
BATF3 basic leucine zipper transcription factor, ATF-like 3 -0.00572324
ADORA2B adenosine A2b receptor -0.00571952
CLDN10 claudin 10 -0.00571299
MVP major vault protein -0.00570266
PLLP plasmolipin -0.00569785
PRPH peripherin -0.00569433
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00569306
ENG endoglin -0.00568049
KRT6B keratin 6B, type II -0.00567963
ZW10 zw10 kinetochore protein -0.00567571
CSTA cystatin A (stefin A) -0.00567066
AOC1 amine oxidase, copper containing 1 -0.00563471
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.00562527
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.0056229
UBE2S ubiquitin-conjugating enzyme E2S -0.00561407
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.00560223
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00560142
NAP1L1 nucleosome assembly protein 1-like 1 -0.00559168
LAX1 lymphocyte transmembrane adaptor 1 -0.00559132
IL10RB interleukin 10 receptor, beta -0.00558886
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 -0.00557458
MSLN mesothelin -0.00555275
NDRG1 N-myc downstream regulated 1 -0.00554699
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00554344
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -0.00552751
TSPAN7 tetraspanin 7 -0.00552463
ESRRA estrogen-related receptor alpha -0.00551839
VCP valosin containing protein -0.00550711
MALL mal, T-cell differentiation protein-like -0.0055034
NES nestin -0.00549278
COL6A1 collagen, type VI, alpha 1 -0.00549138
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00548158
CCN2 cellular communication network factor 2 -0.0054684
FKBP11 FK506 binding protein 11, 19 kDa -0.00546341
PDGFRB platelet-derived growth factor receptor, beta polypeptide -0.00545614
NOP53 NOP53 ribosome biogenesis factor -0.00544802
PTCH1 patched 1 -0.00544297
TBC1D4 TBC1 domain family, member 4 -0.00544115
OPN3 opsin 3 -0.00542968
ATF4 activating transcription factor 4 -0.00541844
PEBP1 phosphatidylethanolamine binding protein 1 -0.00541381
PLK1 polo-like kinase 1 -0.00541131
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -0.00540725
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -0.00540442
TCTN2 tectonic family member 2 -0.00540367
FDXR ferredoxin reductase -0.00539309
PODXL podocalyxin-like -0.00538387
GMFG glia maturation factor, gamma -0.00536918
ARSL arylsulfatase L -0.00536385
KRT81 keratin 81, type II -0.00535321
TESC tescalcin -0.00535237
SOX10 SRY (sex determining region Y)-box 10 -0.00533926
DDAH2 dimethylarginine dimethylaminohydrolase 2 -0.00531207
JAG2 jagged 2 -0.00530292
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00529361
FXYD2 FXYD domain containing ion transport regulator 2 -0.00529166