PIP5K1A Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description phosphatidylinositol-4-phosphate 5-kinase, type I, alpha| (NCBI Entrez Gene Database, 8394)
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Genes

345 genes differentially expressed following the PIP5K1A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
FABP9 fatty acid binding protein 9, testis 3.26818
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.26818
NNT nicotinamide nucleotide transhydrogenase 3.26818
TUBB1 tubulin, beta 1 class VI 3.26818
TLX2 T-cell leukemia homeobox 2 3.26818
GPR20 G protein-coupled receptor 20 3.26818
HCRTR2 hypocretin (orexin) receptor 2 3.26818
TRIM73 tripartite motif containing 73 3.26818
C9ORF72 chromosome 9 open reading frame 72 3.26818
GSTM2 glutathione S-transferase mu 2 (muscle) 3.26818
GSTM5 glutathione S-transferase mu 5 3.26818
PDZD9 PDZ domain containing 9 3.26818
PLVAP plasmalemma vesicle associated protein 3.26818
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.26818
PI16 peptidase inhibitor 16 3.26818
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 3.26818
CELF6 CUGBP, Elav-like family member 6 3.26818
HES7 hes family bHLH transcription factor 7 3.26818
RIMBP2 RIMS binding protein 2 3.26818
DDN dendrin 3.26818
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 3.26818
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.26818
LCN10 lipocalin 10 3.26818
DEFB105A defensin, beta 105A 3.26818
EMCN endomucin 3.26818
RNASE6 ribonuclease, RNase A family, k6 3.26818
RNASE7 ribonuclease, RNase A family, 7 3.26818
BTBD19 BTB (POZ) domain containing 19 3.26818
SMCO1 single-pass membrane protein with coiled-coil domains 1 3.26818
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 3.26818
NRSN1 neurensin 1 3.26818
INTS1 integrator complex subunit 1 3.26818
CPLX3 complexin 3 3.26818
LGALS4 lectin, galactoside-binding, soluble, 4 3.26818
OR51L1 olfactory receptor, family 51, subfamily L, member 1 3.26818
CD68 CD68 molecule 3.26818
SOWAHB sosondowah ankyrin repeat domain family member B 3.26818
TMEM40 transmembrane protein 40 3.26818
IL2RB interleukin 2 receptor, beta 3.26818
ACOT12 acyl-CoA thioesterase 12 3.26818
AVP arginine vasopressin 3.26818
CAPS calcyphosine 3.26818
CD38 CD38 molecule 3.26818
LY6S lymphocyte antigen 6 family member S 3.26818
HTRA4 HtrA serine peptidase 4 3.26818
TMIGD1 transmembrane and immunoglobulin domain containing 1 3.26818
PDF peptide deformylase (mitochondrial) 3.26818
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 3.26818
TRIM31 tripartite motif containing 31 3.26818
ACSL5 acyl-CoA synthetase long-chain family member 5 3.26818
PAPOLB poly(A) polymerase beta (testis specific) 3.26818
DOK7 docking protein 7 3.26818
GIPC3 GIPC PDZ domain containing family, member 3 3.26818
BTBD3 BTB (POZ) domain containing 3 3.26818
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 3.26818
EXOC1L exocyst complex component 1 like 3.26818
NHERF4 NHERF family PDZ scaffold protein 4 3.26818
EZHIP EZH inhibitory protein 3.26818
STPG3 sperm-tail PG-rich repeat containing 3 3.26818
H2AC1 H2A clustered histone 1 3.26818
RTL5 retrotransposon Gag like 5 3.26818
CCDC198 coiled-coil domain containing 198 3.26818
VSIR V-set immunoregulatory receptor 3.26818
ZNF705B zinc finger protein 705B 3.26818
LRRC3C leucine rich repeat containing 3C 3.26818
CCR7 chemokine (C-C motif) receptor 7 3.26818
PCDHA3 protocadherin alpha 3 3.26818
RAB44 RAB44, member RAS oncogene family 3.26818
ACTL8 actin-like 8 3.26818
IL36G interleukin 36, gamma 3.26818
PVRIG poliovirus receptor related immunoglobulin domain containing 3.26818
SPDYE6 speedy/RINGO cell cycle regulator family member E6 3.26818
FAM3D family with sequence similarity 3, member D 3.26818
TBX20 T-box 20 3.26818
LOC107986837 uncharacterized LOC107986837 3.26818
MAGEB2 melanoma antigen family B2 3.26818
ITK IL2-inducible T-cell kinase 3.26818
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.26818
TBX5 T-box 5 3.26818
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.26818
TLR7 toll-like receptor 7 3.26818
NHLRC4 NHL repeat containing 4 3.26818
SIM2 single-minded family bHLH transcription factor 2 3.26818
OR51B5 olfactory receptor, family 51, subfamily B, member 5 3.26818
NXPE1 neurexophilin and PC-esterase domain family, member 1 3.26818
ACR acrosin 3.26818
PGR progesterone receptor 3.26818
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.26818
FGR FGR proto-oncogene, Src family tyrosine kinase 3.26818
TMEM150B transmembrane protein 150B 3.26818
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.26818
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.26818
CPN2 carboxypeptidase N, polypeptide 2 3.26818
CIDEA cell death-inducing DFFA-like effector a 3.26818
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 3.26818
FCN3 ficolin (collagen/fibrinogen domain containing) 3 3.26818
GPR50 G protein-coupled receptor 50 3.26818
RFPL1 ret finger protein-like 1 3.26818
FZD1 frizzled class receptor 1 3.26818
CCDC27 coiled-coil domain containing 27 3.26818
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.26818
STMND1 stathmin domain containing 1 3.26818
DES desmin 3.26818
CD53 CD53 molecule 3.26818
PIH1D2 PIH1 domain containing 2 3.26818
KLHL6 kelch-like family member 6 3.26818
ARR3 arrestin 3, retinal (X-arrestin) 3.26818
SPHKAP SPHK1 interactor, AKAP domain containing 3.26818
BTNL3 butyrophilin-like 3 3.26818
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 3.26818
ZNF132 zinc finger protein 132 3.26818
CTRB1 chymotrypsinogen B1 3.26818
PSG3 pregnancy specific beta-1-glycoprotein 3 3.26818
AKNAD1 AKNA domain containing 1 3.26818
RBBP8NL RBBP8 N-terminal like 3.26818
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 3.26818
EBF2 early B-cell factor 2 3.26818
KLK4 kallikrein-related peptidase 4 3.26818
NPPA natriuretic peptide A 3.26818
HK3 hexokinase 3 (white cell) 3.26818
EPO erythropoietin 3.26818
OR2L3 olfactory receptor, family 2, subfamily L, member 3 3.26818
LRRN4 leucine rich repeat neuronal 4 3.26818
ADAM29 ADAM metallopeptidase domain 29 3.26818
CNGB1 cyclic nucleotide gated channel beta 1 3.26818
ANXA1 annexin A1 3.26818
DRC1 dynein regulatory complex subunit 1 3.26818
MMP10 matrix metallopeptidase 10 3.26818
NKPD1 NTPase, KAP family P-loop domain containing 1 3.26818
TMEM255A transmembrane protein 255A 3.26818
MUC16 mucin 16, cell surface associated 3.26818
KLK6 kallikrein-related peptidase 6 3.26818
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.26818
DKK2 dickkopf WNT signaling pathway inhibitor 2 3.26818
CRTAM cytotoxic and regulatory T cell molecule 3.26818
PLGLB2 plasminogen-like B2 3.26818
CNR2 cannabinoid receptor 2 (macrophage) 3.26818
GPR150 G protein-coupled receptor 150 3.26818
PAGE2B P antigen family, member 2B 3.26818
FITM1 fat storage-inducing transmembrane protein 1 3.26818
LMOD2 leiomodin 2 (cardiac) 3.26818
APOL6 apolipoprotein L, 6 3.26818
GCM2 glial cells missing homolog 2 (Drosophila) 3.26818
CCDC185 coiled-coil domain containing 185 3.26818
CETP cholesteryl ester transfer protein, plasma 3.26818
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.26818
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 3.26818
LRRC31 leucine rich repeat containing 31 3.26818
ADAM18 ADAM metallopeptidase domain 18 3.26818
FCAR Fc fragment of IgA receptor 3.26818
COX7B2 cytochrome c oxidase subunit VIIb2 3.26818
CLCNKA chloride channel, voltage-sensitive Ka 3.26818
PARP8 poly (ADP-ribose) polymerase family, member 8 3.18129
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 3.1629
FPGT fucose-1-phosphate guanylyltransferase 3.1629
DPF3 D4, zinc and double PHD fingers, family 3 3.1629
ADGRE3 adhesion G protein-coupled receptor E3 3.1629
DRAXIN dorsal inhibitory axon guidance protein 2.94699
ABHD2 abhydrolase domain containing 2 2.92635
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 2.86398
MOGS mannosyl-oligosaccharide glucosidase 2.85477
BIK BCL2-interacting killer (apoptosis-inducing) 2.85477
UNC13A unc-13 homolog A (C. elegans) 2.80603
TBC1D23 TBC1 domain family, member 23 2.7597
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 2.72924
C19ORF53 chromosome 19 open reading frame 53 2.59955
VSNL1 visinin-like 1 2.51674
PRKCE protein kinase C, epsilon 2.51504
RAB7A RAB7A, member RAS oncogene family 2.45887
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.44879
FAM240C family with sequence similarity 240 member C 2.44857
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.44705
CPNE4 copine IV 2.43496
MRTFA myocardin related transcription factor A 2.43496
RABGGTA Rab geranylgeranyltransferase, alpha subunit 2.4255
CFAP20DC CFAP20 domain containing 2.39153
CYYR1 cysteine/tyrosine-rich 1 2.32391
OCRL oculocerebrorenal syndrome of Lowe 2.3189
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 2.31389
BFSP1 beaded filament structural protein 1, filensin 2.30114
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 2.30043
METAP2 methionyl aminopeptidase 2 2.28608
HACD1 3-hydroxyacyl-CoA dehydratase 1 2.28608
TNPO1 transportin 1 2.25923
PBX3 pre-B-cell leukemia homeobox 3 2.25418
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.24567
EBNA1BP2 EBNA1 binding protein 2 2.24567
RIPOR3 RIPOR family member 3 2.23725
SUMF1 sulfatase modifying factor 1 2.2319
BLMH bleomycin hydrolase 2.2294
PAAF1 proteasomal ATPase-associated factor 1 2.22713
KLHL20 kelch-like family member 20 2.22713
RNF7 ring finger protein 7 2.19768
LHX1 LIM homeobox 1 2.19392
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 2.19392
HAX1 HCLS1 associated protein X-1 2.19392
TMEM120B transmembrane protein 120B 2.19392
KIRREL2 kin of IRRE like 2 (Drosophila) 2.19392
HLA-DOB major histocompatibility complex, class II, DO beta 2.19392
DAPL1 death associated protein-like 1 2.19392
CDNF cerebral dopamine neurotrophic factor 2.19392
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.19392
PCDHGA7 protocadherin gamma subfamily A, 7 2.19392
BTBD17 BTB (POZ) domain containing 17 2.19392
CD52 CD52 molecule 2.19392
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 2.19392
TENM3 teneurin transmembrane protein 3 2.19392
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.18987
PTGFRN prostaglandin F2 receptor inhibitor 2.18951
BEGAIN brain-enriched guanylate kinase-associated 2.18904
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.18262
TKFC triokinase/FMN cyclase 2.1762
PFKL phosphofructokinase, liver 2.15056
RIC8A RIC8 guanine nucleotide exchange factor A 2.13447
MPND MPN domain containing 2.13447
BCL7A B-cell CLL/lymphoma 7A 2.13378
SH2B1 SH2B adaptor protein 1 2.1011
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 2.08174
GEMIN2 gem (nuclear organelle) associated protein 2 2.07587
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.03311
ATOSA atos homolog A 2.03311
FAM161A family with sequence similarity 161, member A 2.03311
CRACD capping protein inhibiting regulator of actin dynamics 2.01863
ISM1 isthmin 1, angiogenesis inhibitor 2.01863
ACOT8 acyl-CoA thioesterase 8 2.00796
MBD2 methyl-CpG binding domain protein 2 2.0069
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 2.00366

decreased expression

Symbol Name Standardized Value
FAM229A family with sequence similarity 229, member A -3.26818
ZBTB42 zinc finger and BTB domain containing 42 -3.26818
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -3.26818
WBP2NL WBP2 N-terminal like -3.26818
PAQR6 progestin and adipoQ receptor family member VI -3.26818
AZIN2 antizyme inhibitor 2 -3.26818
MAPK11 mitogen-activated protein kinase 11 -3.26818
FAM153A family with sequence similarity 153, member A -3.26818
SCRG1 stimulator of chondrogenesis 1 -3.26818
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -3.26818
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -3.26818
NAT16 N-acetyltransferase 16 (GCN5-related, putative) -3.26818
TICAM1 toll-like receptor adaptor molecule 1 -3.26818
GDNF glial cell derived neurotrophic factor -3.26818
MOGAT1 monoacylglycerol O-acyltransferase 1 -3.26818
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -3.26818
LCN15 lipocalin 15 -3.26818
TNS4 tensin 4 -3.26818
FGF8 fibroblast growth factor 8 (androgen-induced) -3.26818
CA3 carbonic anhydrase III -3.26818
TMPRSS11E transmembrane protease, serine 11E -3.26818
GREM2 gremlin 2, DAN family BMP antagonist -3.26818
CLCNKB chloride channel, voltage-sensitive Kb -3.26818
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -3.26818
PCDHB15 protocadherin beta 15 -3.26818
SRRM1 serine/arginine repetitive matrix 1 -3.26818
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -3.26818
TTC16 tetratricopeptide repeat domain 16 -3.26818
PGLYRP1 peptidoglycan recognition protein 1 -3.26818
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -3.26818
CFAP61 cilia and flagella associated protein 61 -3.26818
SCNN1D sodium channel, non voltage gated 1 delta subunit -3.26818
IL1R1 interleukin 1 receptor, type I -3.26818
KLB klotho beta -3.26818
GFY golgi-associated, olfactory signaling regulator -3.26818
TMEM225B transmembrane protein 225B -3.26818
ACP4 acid phosphatase 4 -3.26818
RASAL1 RAS protein activator like 1 (GAP1 like) -3.26818
ZNF181 zinc finger protein 181 -3.26818
MYOT myotilin -3.26818
CATSPERT catsper channel auxiliary subunit tau -3.26818
MYH13 myosin, heavy chain 13, skeletal muscle -3.26818
RHPN1 rhophilin, Rho GTPase binding protein 1 -3.26818
LTBP2 latent transforming growth factor beta binding protein 2 -3.26818
CHADL chondroadherin-like -3.26818
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -3.22268
VASH1 vasohibin 1 -3.14153
CARD14 caspase recruitment domain family, member 14 -3.14153
AURKC aurora kinase C -3.04991
LAT linker for activation of T cells -2.8965
FAM43A family with sequence similarity 43, member A -2.8965
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.85477
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.80083
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -2.80083
MRPS25 mitochondrial ribosomal protein S25 -2.76378
CLPSL1 colipase-like 1 -2.74023
RBM8A RNA binding motif protein 8A -2.70774
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase -2.67215
TEX264 testis expressed 264 -2.6495
NME8 NME/NM23 family member 8 -2.63394
PNMA3 paraneoplastic Ma antigen 3 -2.63164
C2ORF42 chromosome 2 open reading frame 42 -2.60346
NGEF neuronal guanine nucleotide exchange factor -2.59823
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 -2.5832
CDH12 cadherin 12, type 2 (N-cadherin 2) -2.56436
ABHD17B abhydrolase domain containing 17B -2.54756
RNF212 ring finger protein 212 -2.51674
YPEL5 yippee-like 5 (Drosophila) -2.51504
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -2.50989
ITM2B integral membrane protein 2B -2.4849
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 -2.43496
ABR active BCR-related -2.43496
HIRIP3 HIRA interacting protein 3 -2.4255
WDR62 WD repeat domain 62 -2.42488
BBS10 Bardet-Biedl syndrome 10 -2.39153
TXLNA taxilin alpha -2.39153
RGS14 regulator of G-protein signaling 14 -2.39153
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.38804
RPS23 ribosomal protein S23 -2.37408
NDFIP2 Nedd4 family interacting protein 2 -2.3647
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -2.36371
PDIA3 protein disulfide isomerase family A, member 3 -2.3189
FLNC filamin C, gamma -2.28718
RRAGD Ras-related GTP binding D -2.28015
ZFP62 ZFP62 zinc finger protein -2.26536
GRK5 G protein-coupled receptor kinase 5 -2.21127
ZNF157 zinc finger protein 157 -2.21059
IL7 interleukin 7 -2.19978
SLX9 SLX9 ribosome biogenesis factor -2.19978
ZNF396 zinc finger protein 396 -2.19978
UPK1A uroplakin 1A -2.19392
DCLRE1C DNA cross-link repair 1C -2.19392
SP140L SP140 nuclear body protein-like -2.19392
ASB8 ankyrin repeat and SOCS box containing 8 -2.19392
EID3 EP300 interacting inhibitor of differentiation 3 -2.19392
LPAR6 lysophosphatidic acid receptor 6 -2.19392
CNTNAP1 contactin associated protein 1 -2.19392
SMKR1 small lysine-rich protein 1 -2.19392
PKD1L3 polycystic kidney disease 1-like 3 -2.18951
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 -2.18951
CCDC77 coiled-coil domain containing 77 -2.17689
RNF25 ring finger protein 25 -2.16868
AUNIP aurora kinase A and ninein interacting protein -2.15333
MMS22L MMS22-like, DNA repair protein -2.13378
TMEM250 transmembrane protein 250 -2.13378
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -2.12605
GMPS guanine monphosphate synthase -2.12548
AKAP9 A kinase (PRKA) anchor protein 9 -2.11442
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -2.10593
DLG1 discs, large homolog 1 (Drosophila) -2.08194
RNF187 ring finger protein 187 -2.04286
ZIK1 zinc finger protein interacting with K protein 1 -2.03708
H4C4 H4 clustered histone 4 -2.02375
FDPS farnesyl diphosphate synthase -2.02375
SMN2 survival of motor neuron 2, centromeric -2.02375
CCDC159 coiled-coil domain containing 159 -2.01863
KIAA2013 KIAA2013 -2.01863
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -2.0123