| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/PKCA_DN.V1_UP |
| Similar Terms | |
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335 genes differentially expressed following the PKCA_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ACHE | acetylcholinesterase (Yt blood group) |
| ACOT12 | acyl-CoA thioesterase 12 |
| ADA | adenosine deaminase |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADCY3 | adenylate cyclase 3 |
| ADORA2B | adenosine A2b receptor |
| ADRA1A | adrenoceptor alpha 1A |
| AFP | alpha-fetoprotein |
| AGXT | alanine-glyoxylate aminotransferase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARSG | arylsulfatase G |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| BSN | bassoon presynaptic cytomatrix protein |
| C3ORF62 | chromosome 3 open reading frame 62 |
| CA2 | carbonic anhydrase II |
| CABP5 | calcium binding protein 5 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CCL24 | chemokine (C-C motif) ligand 24 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CDIP1 | cell death-inducing p53 target 1 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa |
| CELA3A | chymotrypsin-like elastase family, member 3A |
| CES1 | carboxylesterase 1 |
| CLEC4A | C-type lectin domain family 4, member A |
| CMTR2 | cap methyltransferase 2 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRYGB | crystallin, gamma B |
| CXCL17 | chemokine (C-X-C motif) ligand 17 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DIO1 | deiodinase, iodothyronine, type I |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 |
| DLX1 | distal-less homeobox 1 |
| EGR3 | early growth response 3 |
| EGR4 | early growth response 4 |
| ELMOD3 | ELMO/CED-12 domain containing 3 |
| ENPP3 | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
| FBLN1 | fibulin 1 |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FERD3L | Fer3-like bHLH transcription factor |
| FGF19 | fibroblast growth factor 19 |
| FMR1NB | fragile X mental retardation 1 neighbor |
| G6PC | glucose-6-phosphatase, catalytic subunit |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GATA4 | GATA binding protein 4 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GFAP | glial fibrillary acidic protein |
| GHRL | ghrelin/obestatin prepropeptide |
| GLI2 | GLI family zinc finger 2 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPR155 | G protein-coupled receptor 155 |
| GSTA2 | glutathione S-transferase alpha 2 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTM1 | glutathione S-transferase mu 1 |
| GSTM4 | glutathione S-transferase mu 4 |
| GSTT1 | glutathione S-transferase theta 1 |
| HLA-E | major histocompatibility complex, class I, E |
| HOXB4 | homeobox B4 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IL15 | interleukin 15 |
| IL33 | interleukin 33 |
| KERA | keratocan |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF15 | Kruppel-like factor 15 |
| LCT | lactase |
| LEAP2 | liver expressed antimicrobial peptide 2 |
| LECT2 | leukocyte cell-derived chemotaxin 2 |
| LIX1 | Lix1 homolog (chicken) |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LPO | lactoperoxidase |
| LTB4R | leukotriene B4 receptor |
| LTC4S | leukotriene C4 synthase |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MRAP | melanocortin 2 receptor accessory protein |
| MUSK | muscle, skeletal, receptor tyrosine kinase |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NMT2 | N-myristoyltransferase 2 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR1I3 | nuclear receptor subfamily 1, group I, member 3 |
| NRG4 | neuregulin 4 |
| NXNL1 | nucleoredoxin-like 1 |
| NXNL2 | nucleoredoxin-like 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR51B6 | olfactory receptor, family 51, subfamily B, member 6 |
| ORMDL3 | ORMDL sphingolipid biosynthesis regulator 3 |
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 |
| PAQR7 | progestin and adipoQ receptor family member VII |
| PASK | PAS domain containing serine/threonine kinase |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PER2 | period circadian clock 2 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
| PIPOX | pipecolic acid oxidase |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNA3 | plexin A3 |
| POMC | proopiomelanocortin |
| PPAPDC3 | phosphatidic acid phosphatase type 2 domain containing 3 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PROP1 | PROP paired-like homeobox 1 |
| PSAPL1 | prosaposin-like 1 (gene/pseudogene) |
| PSMC3IP | PSMC3 interacting protein |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB30 | RAB30, member RAS oncogene family |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like |
| RDH12 | retinol dehydrogenase 12 (all-trans/9-cis/11-cis) |
| RDH16 | retinol dehydrogenase 16 (all-trans) |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| REG1A | regenerating islet-derived 1 alpha |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RTBDN | retbindin |
| S100G | S100 calcium binding protein G |
| SCOC | short coiled-coil protein |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 |
| SHISA2 | shisa family member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC2A2 | solute carrier family 2 (facilitated glucose transporter), member 2 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC5A4 | solute carrier family 5 (glucose activated ion channel), member 4 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) |
| SP6 | Sp6 transcription factor |
| SPNS2 | spinster homolog 2 (Drosophila) |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 |
| SSBP2 | single-stranded DNA binding protein 2 |
| TCHH | trichohyalin |
| TEF | thyrotrophic embryonic factor |
| TET1 | tet methylcytosine dioxygenase 1 |
| TMEM135 | transmembrane protein 135 |
| TMEM56 | transmembrane protein 56 |
| TPMT | thiopurine S-methyltransferase |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TREH | trehalase (brush-border membrane glycoprotein) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTI1 | TELO2 interacting protein 1 |
| TUB | tubby bipartite transcription factor |
| TUBB2B | tubulin, beta 2B class IIb |
| TYMP | thymidine phosphorylase |
| UBD | ubiquitin D |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 |
| UPB1 | ureidopropionase, beta |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VWA1 | von Willebrand factor A domain containing 1 |
| WISP2 | WNT1 inducible signaling pathway protein 2 |
| WNT10A | wingless-type MMTV integration site family, member 10A |
| YJEFN3 | YjeF N-terminal domain containing 3 |
| ZBTB7C | zinc finger and BTB domain containing 7C |
| ZFPM1 | zinc finger protein, FOG family member 1 |
| ZIM3 | zinc finger, imprinted 3 |
| ZNF865 | zinc finger protein 865 |
| Symbol | Name |
|---|---|
| ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ACOT1 | acyl-CoA thioesterase 1 |
| ADAM11 | ADAM metallopeptidase domain 11 |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| ADM | adrenomedullin |
| AGO2 | argonaute RISC catalytic component 2 |
| AHSG | alpha-2-HS-glycoprotein |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| APOC1 | apolipoprotein C-I |
| APOF | apolipoprotein F |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| BARD1 | BRCA1 associated RING domain 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BEX1 | brain expressed, X-linked 1 |
| BID | BH3 interacting domain death agonist |
| CA3 | carbonic anhydrase III |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAMP | cathelicidin antimicrobial peptide |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD19 | CD19 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CENPF | centromere protein F, 350/400kDa |
| CENPT | centromere protein T |
| CFD | complement factor D (adipsin) |
| CFH | complement factor H |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CKAP4 | cytoskeleton-associated protein 4 |
| CLEC4D | C-type lectin domain family 4, member D |
| CLEC7A | C-type lectin domain family 7, member A |
| COCH | cochlin |
| COL25A1 | collagen, type XXV, alpha 1 |
| CP | ceruloplasmin (ferroxidase) |
| CPT1B | carnitine palmitoyltransferase 1B (muscle) |
| CYGB | cytoglobin |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DENND1B | DENN/MADD domain containing 1B |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNAH8 | dynein, axonemal, heavy chain 8 |
| DUOXA2 | dual oxidase maturation factor 2 |
| EAF2 | ELL associated factor 2 |
| ECE2 | endothelin converting enzyme 2 |
| EDN3 | endothelin 3 |
| EIF4E3 | eukaryotic translation initiation factor 4E family member 3 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| ETV3 | ets variant 3 |
| EXT1 | exostosin glycosyltransferase 1 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM198B | family with sequence similarity 198, member B |
| FAM86B2 | family with sequence similarity 86, member B2 |
| FANCI | Fanconi anemia, complementation group I |
| FERMT3 | fermitin family member 3 |
| FXYD4 | FXYD domain containing ion transport regulator 4 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAS2 | growth arrest-specific 2 |
| GATAD2B | GATA zinc finger domain containing 2B |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GGNBP2 | gametogenetin binding protein 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GLDC | glycine dehydrogenase (decarboxylating) |
| HES7 | hes family bHLH transcription factor 7 |
| HK2 | hexokinase 2 |
| HOXC8 | homeobox C8 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IGH | immunoglobulin heavy locus |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGHM | immunoglobulin heavy constant mu |
| IL36A | interleukin 36, alpha |
| IRX1 | iroquois homeobox 1 |
| ITGB6 | integrin, beta 6 |
| ITGB7 | integrin, beta 7 |
| KANK2 | KN motif and ankyrin repeat domains 2 |
| KCNIP2 | Kv channel interacting protein 2 |
| KIAA1033 | KIAA1033 |
| KLHL1 | kelch-like family member 1 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LPL | lipoprotein lipase |
| MAGT1 | magnesium transporter 1 |
| MALAT1 | metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| METTL1 | methyltransferase like 1 |
| MGAT4C | MGAT4 family, member C |
| MSC | musculin |
| MT4 | metallothionein 4 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYO1B | myosin IB |
| NANOS2 | nanos homolog 2 (Drosophila) |
| NEUROD4 | neuronal differentiation 4 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| NKX2-1 | NK2 homeobox 1 |
| NOP58 | NOP58 ribonucleoprotein |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NUCB2 | nucleobindin 2 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCDHB15 | protocadherin beta 15 |
| PDGFC | platelet derived growth factor C |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PLA2G2E | phospholipase A2, group IIE |
| PLAU | plasminogen activator, urokinase |
| POU3F4 | POU class 3 homeobox 4 |
| PRKCA | protein kinase C, alpha |
| PROCR | protein C receptor, endothelial |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSPC1 | paraspeckle component 1 |
| PTK6 | protein tyrosine kinase 6 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHOJ | ras homolog family member J |
| RWDD3 | RWD domain containing 3 |
| SAA1 | serum amyloid A1 |
| SAA2 | serum amyloid A2 |
| SAA3P | serum amyloid A3 pseudogene |
| SEC1P | secretory blood group 1, pseudogene |
| SEMA6C | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C |
| SERINC4 | serine incorporator 4 |
| SHF | Src homology 2 domain containing F |
| SIK1 | salt-inducible kinase 1 |
| SLC10A2 | solute carrier family 10 (sodium/bile acid cotransporter), member 2 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC32A1 | solute carrier family 32 (GABA vesicular transporter), member 1 |
| SLC46A2 | solute carrier family 46, member 2 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SPRR2F | small proline-rich protein 2F |
| ST6GALNAC1 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| SUOX | sulfite oxidase |
| SYT12 | synaptotagmin XII |
| TIFA | TRAF-interacting protein with forkhead-associated domain |
| TLR2 | toll-like receptor 2 |
| TMIGD1 | transmembrane and immunoglobulin domain containing 1 |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNNI2 | troponin I type 2 (skeletal, fast) |
| TRIB1 | tribbles pseudokinase 1 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| TTC36 | tetratricopeptide repeat domain 36 |
| TWF2 | twinfilin actin binding protein 2 |
| TXNRD2 | thioredoxin reductase 2 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| WAS | Wiskott-Aldrich syndrome |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WDR5 | WD repeat domain 5 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC1 | zinc finger, DHHC-type containing 1 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZNF319 | zinc finger protein 319 |
| ZNF503 | zinc finger protein 503 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
