| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | polycystic kidney disease 2 (autosomal dominant)|This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011] (NCBI Entrez Gene Database, 5311) |
| External Link | https://ncbi.nlm.nih.gov/gene/5311 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PKD2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC38A1 | solute carrier family 38, member 1 | 0.0148261 |
| CFD | complement factor D (adipsin) | 0.0144568 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.0136208 |
| MT1H | metallothionein 1H | 0.0127426 |
| TNC | tenascin C | 0.0121644 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.0118771 |
| CFH | complement factor H | 0.0114305 |
| ZBTB16 | zinc finger and BTB domain containing 16 | 0.0109666 |
| RBM47 | RNA binding motif protein 47 | 0.0109352 |
| DPP8 | dipeptidyl-peptidase 8 | 0.0108604 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0107804 |
| HEPH | hephaestin | 0.0106895 |
| COL15A1 | collagen, type XV, alpha 1 | 0.0105623 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0103593 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0103181 |
| MT1X | metallothionein 1X | 0.0102875 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0102173 |
| MT1G | metallothionein 1G | 0.010166 |
| ACKR3 | atypical chemokine receptor 3 | 0.010112 |
| SRGN | serglycin | 0.010052 |
| TAOK3 | TAO kinase 3 | 0.0100016 |
| APOD | apolipoprotein D | 0.00994074 |
| PALLD | palladin, cytoskeletal associated protein | 0.00993235 |
| NFIB | nuclear factor I/B | 0.00992875 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00986311 |
| FCGBP | Fc fragment of IgG binding protein | 0.00985841 |
| DMD | dystrophin | 0.00968431 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.0096319 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00960036 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.0095242 |
| KRT17 | keratin 17, type I | 0.00946375 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00946105 |
| COMT | catechol-O-methyltransferase | 0.00929076 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00928943 |
| IFNGR1 | interferon gamma receptor 1 | 0.00920986 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0091827 |
| INHBB | inhibin, beta B | 0.00917898 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00914591 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0091385 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00912527 |
| C5ORF28 | chromosome 5 open reading frame 28 | 0.00910907 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.00909521 |
| SERINC5 | serine incorporator 5 | 0.0090939 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.00900663 |
| MT1F | metallothionein 1F | 0.00885469 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00876272 |
| CHGB | chromogranin B | 0.00873429 |
| CP | ceruloplasmin (ferroxidase) | 0.00872026 |
| MT2A | metallothionein 2A | 0.00871675 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00867915 |
| FGB | fibrinogen beta chain | 0.00865726 |
| COG5 | component of oligomeric golgi complex 5 | 0.00863754 |
| PCDH9 | protocadherin 9 | 0.00854713 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00852259 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00851095 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00850729 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00850208 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | 0.00845541 |
| COL3A1 | collagen, type III, alpha 1 | 0.00842591 |
| TWF1 | twinfilin actin binding protein 1 | 0.00839405 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00838135 |
| MAOA | monoamine oxidase A | 0.00837978 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.0083733 |
| ABHD3 | abhydrolase domain containing 3 | 0.0083617 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00835939 |
| FABP1 | fatty acid binding protein 1, liver | 0.00832977 |
| SEPTIN10 | septin 10 | 0.00828733 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00827331 |
| KYNU | kynureninase | 0.00823414 |
| SDC2 | syndecan 2 | 0.00821919 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.00819348 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00811861 |
| VCL | vinculin | 0.0080757 |
| TMED5 | transmembrane emp24 protein transport domain containing 5 | 0.0080416 |
| CD99 | CD99 molecule | 0.00803252 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.0080301 |
| GLA | galactosidase, alpha | 0.00801007 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00799159 |
| PCNA | proliferating cell nuclear antigen | 0.00794788 |
| SYNM | synemin, intermediate filament protein | 0.00792375 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00787779 |
| RHOF | ras homolog family member F (in filopodia) | 0.00787389 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00787241 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00786284 |
| TPD52 | tumor protein D52 | 0.00786192 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00785368 |
| PTHLH | parathyroid hormone-like hormone | 0.0078359 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.00781735 |
| CHN1 | chimerin 1 | 0.00779705 |
| EMC2 | ER membrane protein complex subunit 2 | 0.00778517 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00777291 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.00773966 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.00772195 |
| KRT81 | keratin 81, type II | 0.00766394 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00763091 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00757957 |
| NPTN | neuroplastin | 0.00757115 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00753488 |
| MMP12 | matrix metallopeptidase 12 | 0.00752414 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | 0.00750268 |
| KRT14 | keratin 14, type I | 0.00749257 |
| E2F2 | E2F transcription factor 2 | 0.00749179 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00743679 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.00740908 |
| DST | dystonin | 0.00739914 |
| POSTN | periostin, osteoblast specific factor | 0.00737914 |
| CAV2 | caveolin 2 | 0.00736799 |
| MSX1 | msh homeobox 1 | 0.00736279 |
| PERP | PERP, TP53 apoptosis effector | 0.00735813 |
| CLCA4 | chloride channel accessory 4 | 0.00735599 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00735058 |
| HHEX | hematopoietically expressed homeobox | 0.00734762 |
| MT1M | metallothionein 1M | 0.00734195 |
| ASPH | aspartate beta-hydroxylase | 0.00733625 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 | 0.0073198 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | 0.00731959 |
| COL5A2 | collagen, type V, alpha 2 | 0.00731838 |
| IRS2 | insulin receptor substrate 2 | 0.00730369 |
| RIN2 | Ras and Rab interactor 2 | 0.00729119 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00728094 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.00727191 |
| WASHC4 | WASH complex subunit 4 | 0.00724124 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00723505 |
| MELK | maternal embryonic leucine zipper kinase | 0.00721686 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00717702 |
| GAL | galanin/GMAP prepropeptide | 0.00717315 |
| GSDME | gasdermin E | 0.00716673 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00715226 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00715157 |
| TM4SF20 | transmembrane 4 L six family member 20 | 0.00714164 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00713908 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0071323 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.00712726 |
| KCTD5 | potassium channel tetramerization domain containing 5 | 0.00710643 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.00708895 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00708542 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00708533 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0070766 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.00706598 |
| PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 0.00706402 |
| HBP1 | HMG-box transcription factor 1 | 0.00706364 |
| TJP1 | tight junction protein 1 | 0.00704859 |
| TMEM100 | transmembrane protein 100 | 0.00703595 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0070142 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.00697582 |
| RTN4 | reticulon 4 | 0.00696155 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00695816 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.0069457 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0069283 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00692132 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00691395 |
| STX4 | syntaxin 4 | 0.00690714 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00689981 |
| HOPX | HOP homeobox | 0.00689588 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.00688948 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.00687415 |
| TP63 | tumor protein p63 | 0.0068691 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00685357 |
| MATN2 | matrilin 2 | 0.00685109 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00682379 |
| THSD7A | thrombospondin, type I, domain containing 7A | 0.00681188 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.00681142 |
| PRMT3 | protein arginine methyltransferase 3 | 0.00680182 |
| PLTP | phospholipid transfer protein | 0.00680107 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | 0.00679347 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00679282 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.00678874 |
| TG | thyroglobulin | 0.00678099 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00674384 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00673977 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0067319 |
| GALC | galactosylceramidase | 0.00671865 |
| PLAU | plasminogen activator, urokinase | 0.00671836 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.00669641 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.00667427 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00666478 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00664637 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0066384 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 | 0.00660027 |
| CLU | clusterin | 0.00659764 |
| KRT23 | keratin 23, type I | 0.00657058 |
| MPDZ | multiple PDZ domain protein | 0.006569 |
| MAGEA3 | melanoma antigen family A3 | 0.00656568 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00655361 |
| KRT7 | keratin 7, type II | 0.00655072 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.0065502 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00654194 |
| HEATR1 | HEAT repeat containing 1 | 0.00653827 |
| BCAP29 | B-cell receptor-associated protein 29 | 0.00651993 |
| FERMT2 | fermitin family member 2 | 0.00651595 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00650756 |
| DENND4C | DENN/MADD domain containing 4C | 0.00649465 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.0064895 |
| GMFB | glia maturation factor, beta | 0.0064827 |
| CCDC68 | coiled-coil domain containing 68 | 0.00648164 |
| MYO10 | myosin X | 0.00647816 |
| COQ10B | coenzyme Q10 homolog B (S. cerevisiae) | 0.0064656 |
| VSNL1 | visinin-like 1 | 0.00646374 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0064584 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0064532 |
| DLD | dihydrolipoamide dehydrogenase | 0.00642431 |
| EMP1 | epithelial membrane protein 1 | 0.00641259 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00640159 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00638199 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00636931 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00636083 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00635595 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0063542 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00633597 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00633542 |
| PLPP3 | phospholipid phosphatase 3 | 0.0063351 |
| CHMP5 | charged multivesicular body protein 5 | 0.00632704 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | 0.00631198 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0063081 |
| GPM6B | glycoprotein M6B | 0.00630211 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00630133 |
| ZFR | zinc finger RNA binding protein | 0.00630004 |
| RBM26 | RNA binding motif protein 26 | 0.00629907 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00629713 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00629529 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00627963 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00626739 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00626235 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00625975 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | 0.00624344 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00622586 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00622173 |
| TBC1D31 | TBC1 domain family, member 31 | 0.00621463 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.00620131 |
| DMXL1 | Dmx-like 1 | 0.00619736 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.00619443 |
| PIR | pirin (iron-binding nuclear protein) | 0.00618518 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | 0.00617902 |
| DSP | desmoplakin | 0.00617645 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00617255 |
| MED13 | mediator complex subunit 13 | 0.00616031 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 0.00615601 |
| FRZB | frizzled-related protein | 0.00614559 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00613376 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.00612432 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0061242 |
| SERINC1 | serine incorporator 1 | 0.00611408 |
| MT1E | metallothionein 1E | 0.00610607 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00609476 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.00608393 |
| INSL4 | insulin-like 4 (placenta) | 0.00606683 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 0.00606462 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00605353 |
| TMEM106B | transmembrane protein 106B | 0.0060372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0139591 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0127667 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0125907 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0116398 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0112122 |
| DACH1 | dachshund family transcription factor 1 | -0.0111652 |
| ASRGL1 | asparaginase like 1 | -0.0108654 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0107837 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0107823 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.0106324 |
| MLF1 | myeloid leukemia factor 1 | -0.0104816 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0104605 |
| GNAS | GNAS complex locus | -0.0104517 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0104271 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.01037 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.0101598 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.00988108 |
| CFI | complement factor I | -0.00986582 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0097755 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.00976046 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00975901 |
| H1-0 | H1.0 linker histone | -0.00971231 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00947498 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00944372 |
| EMX2 | empty spiracles homeobox 2 | -0.00943749 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00943242 |
| NMU | neuromedin U | -0.00942021 |
| FOLR1 | folate receptor 1 (adult) | -0.00939186 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00934455 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00930196 |
| CLDN10 | claudin 10 | -0.00924246 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00902199 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00895673 |
| SORT1 | sortilin 1 | -0.00895578 |
| LTF | lactotransferrin | -0.00893108 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0089102 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00881799 |
| THBS1 | thrombospondin 1 | -0.00878352 |
| AUTS2 | autism susceptibility candidate 2 | -0.00867037 |
| PLXNA2 | plexin A2 | -0.00858804 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00850988 |
| RPL10 | ribosomal protein L10 | -0.00848154 |
| CHMP4A | charged multivesicular body protein 4A | -0.00832806 |
| TEX10 | testis expressed 10 | -0.00826665 |
| GPX4 | glutathione peroxidase 4 | -0.00824364 |
| MRPL23 | mitochondrial ribosomal protein L23 | -0.00821364 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00816514 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00809013 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00806923 |
| ESR1 | estrogen receptor 1 | -0.00804717 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00800969 |
| SFTPD | surfactant protein D | -0.00799295 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | -0.00796535 |
| NPTX2 | neuronal pentraxin II | -0.00794722 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0079282 |
| GPX1 | glutathione peroxidase 1 | -0.00792799 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.00789035 |
| AK1 | adenylate kinase 1 | -0.00788156 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.0078725 |
| ATF5 | activating transcription factor 5 | -0.00786073 |
| RHOB | ras homolog family member B | -0.00785733 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.007836 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00781958 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00780774 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00776686 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -0.00773326 |
| EPCAM | epithelial cell adhesion molecule | -0.00770022 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00767895 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | -0.00767351 |
| LCN2 | lipocalin 2 | -0.00760242 |
| SNRNP25 | small nuclear ribonucleoprotein 25kDa (U11/U12) | -0.00755362 |
| ABHD17A | abhydrolase domain containing 17A | -0.00750615 |
| ERGIC3 | ERGIC and golgi 3 | -0.00748046 |
| GYPC | glycophorin C (Gerbich blood group) | -0.00747067 |
| NANOG | Nanog homeobox | -0.00745774 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00740983 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00738582 |
| COA3 | cytochrome c oxidase assembly factor 3 | -0.00732791 |
| PLLP | plasmolipin | -0.00730526 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00728987 |
| KLK11 | kallikrein-related peptidase 11 | -0.0072774 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0072723 |
| NARF | nuclear prelamin A recognition factor | -0.00726192 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00723151 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00722076 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00718701 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0071289 |
| LYZ | lysozyme | -0.0071066 |
| MLPH | melanophilin | -0.00710607 |
| FBXO21 | F-box protein 21 | -0.00710348 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00709725 |
| PLAT | plasminogen activator, tissue | -0.00708756 |
| OPHN1 | oligophrenin 1 | -0.00708486 |
| ECM1 | extracellular matrix protein 1 | -0.00707667 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.0070607 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | -0.00703495 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00701748 |
| ANXA6 | annexin A6 | -0.00701662 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0070128 |
| MRPL20 | mitochondrial ribosomal protein L20 | -0.00695088 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00694393 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00693682 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00690966 |
| ZNF593 | zinc finger protein 593 | -0.00690708 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00689021 |
| CST3 | cystatin C | -0.00688719 |
| SARS1 | seryl-tRNA synthetase 1 | -0.00687083 |
| CYB561 | cytochrome b561 | -0.00686497 |
| MSLN | mesothelin | -0.00685528 |
| TRAPPC2L | trafficking protein particle complex 2-like | -0.00683991 |
| PRMT1 | protein arginine methyltransferase 1 | -0.0068383 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00682789 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00682462 |
| THBS2 | thrombospondin 2 | -0.00681347 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.00680619 |
| CAPN3 | calpain 3, (p94) | -0.00680164 |
| CD52 | CD52 molecule | -0.00679836 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00679438 |
| C19ORF53 | chromosome 19 open reading frame 53 | -0.00678212 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00675055 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00672998 |
| CDC34 | cell division cycle 34 | -0.00671629 |
| TSPYL5 | TSPY-like 5 | -0.00668843 |
| POLR2E | polymerase (RNA) II (DNA directed) polypeptide E, 25kDa | -0.0066684 |
| FAM149A | family with sequence similarity 149, member A | -0.00666718 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00666243 |
| C21ORF91 | chromosome 21 open reading frame 91 | -0.00664477 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00664282 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00661826 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | -0.00656762 |
| PITX3 | paired-like homeodomain 3 | -0.00654831 |
| PROM1 | prominin 1 | -0.00654596 |
| CTSH | cathepsin H | -0.0065449 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.0065413 |
| HDAC9 | histone deacetylase 9 | -0.00653751 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00653361 |
| MGAM | maltase-glucoamylase | -0.00651233 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00649983 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00649791 |
| MEX3D | mex-3 RNA binding family member D | -0.00648954 |
| RGS4 | regulator of G-protein signaling 4 | -0.00648833 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00647542 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00646278 |
| RAB15 | RAB15, member RAS oncogene family | -0.00646171 |
| RPS5 | ribosomal protein S5 | -0.00646069 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00645045 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00644874 |
| RETREG1 | reticulophagy regulator 1 | -0.00643481 |
| NUTF2 | nuclear transport factor 2 | -0.00642485 |
| ODC1 | ornithine decarboxylase 1 | -0.00639133 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.00638145 |
| ANO3 | anoctamin 3 | -0.0063703 |
| ARMC9 | armadillo repeat containing 9 | -0.00636726 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | -0.00636539 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0063525 |
| MEF2A | myocyte enhancer factor 2A | -0.00634664 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00632075 |
| GUK1 | guanylate kinase 1 | -0.00631317 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00630505 |
| HRAS | Harvey rat sarcoma viral oncogene homolog | -0.00630088 |
| SCAND1 | SCAN domain containing 1 | -0.00629026 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00629007 |
| THY1 | Thy-1 cell surface antigen | -0.00626204 |
| ZW10 | zw10 kinetochore protein | -0.00624953 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.00623407 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | -0.00623406 |
| TYRO3 | TYRO3 protein tyrosine kinase | -0.00623255 |
| GMPR | guanosine monophosphate reductase | -0.00621931 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.00621477 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00620629 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00620404 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00619574 |
| MTHFD1 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | -0.00617876 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00615287 |
| CHD8 | chromodomain helicase DNA binding protein 8 | -0.00615109 |
| HSD17B10 | hydroxysteroid (17-beta) dehydrogenase 10 | -0.00614605 |
| CD200 | CD200 molecule | -0.00613679 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.00613574 |
| OLFM4 | olfactomedin 4 | -0.00612437 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00612074 |
| BEX1 | brain expressed, X-linked 1 | -0.00611256 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | -0.0061031 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00609339 |
| RGS3 | regulator of G-protein signaling 3 | -0.00607429 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -0.00607381 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00607341 |
| PAIP2B | poly(A) binding protein interacting protein 2B | -0.00605074 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00604808 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00604735 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00603978 |
| BCR | breakpoint cluster region | -0.00603704 |
| BIN1 | bridging integrator 1 | -0.00603647 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00603464 |
| VCAN | versican | -0.00603378 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0060193 |
| POU5F1B | POU class 5 homeobox 1B | -0.00600708 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00600579 |
| CDC20 | cell division cycle 20 | -0.00600274 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00599898 |
| DPY19L2P2 | DPY19L2 pseudogene 2 | -0.00599686 |
| EVI2A | ecotropic viral integration site 2A | -0.00599544 |
| NXN | nucleoredoxin | -0.00599183 |
| SDC1 | syndecan 1 | -0.00596455 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | -0.00595967 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00595804 |
| PYCARD | PYD and CARD domain containing | -0.00595225 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00594538 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -0.00594154 |
| NDUFB2 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa | -0.0059415 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00594107 |
| MGP | matrix Gla protein | -0.00593313 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00593193 |
| KLF2 | Kruppel-like factor 2 | -0.00592063 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00591528 |
| CRYM | crystallin, mu | -0.00591361 |
| C20ORF27 | chromosome 20 open reading frame 27 | -0.00591328 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 | -0.00591308 |
| MAGED1 | melanoma antigen family D1 | -0.00591181 |
| CHN2 | chimerin 2 | -0.00589649 |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 | -0.0058891 |
| MYRF | myelin regulatory factor | -0.00588433 |
| RPA2 | replication protein A2, 32kDa | -0.00588268 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00586794 |
| PRMT5 | protein arginine methyltransferase 5 | -0.00586057 |
| TEAD4 | TEA domain family member 4 | -0.00585902 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00585882 |
| EML1 | echinoderm microtubule associated protein like 1 | -0.00584993 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00582965 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 | -0.00582917 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | -0.0058286 |
| RAB3B | RAB3B, member RAS oncogene family | -0.0058208 |
| TP53 | tumor protein p53 | -0.00581955 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.00580989 |
| CCDC85B | coiled-coil domain containing 85B | -0.00580497 |
| BEX4 | brain expressed, X-linked 4 | -0.00580146 |
| PTK7 | protein tyrosine kinase 7 (inactive) | -0.00579465 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.005783 |
| ATG101 | autophagy related 101 | -0.0057753 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0057726 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00576112 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00574804 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00574338 |
| BSPRY | B-box and SPRY domain containing | -0.00573684 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00573089 |
| AHCY | adenosylhomocysteinase | -0.00571781 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0057091 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00570687 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.00570476 |
| RNF167 | ring finger protein 167 | -0.00569647 |
| COL2A1 | collagen, type II, alpha 1 | -0.00568309 |
