PKD2L1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description polycystic kidney disease 2-like 1|This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] (NCBI Entrez Gene Database, 9033)
External Link https://ncbi.nlm.nih.gov/gene/9033
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Genes

500 genes differentially expressed following the PKD2L1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XPO7 exportin 7 0.0113097
KLK10 kallikrein-related peptidase 10 0.0110861
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.0103564
KLK11 kallikrein-related peptidase 11 0.0102228
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0100984
KRT14 keratin 14, type I 0.0098784
TM4SF1 transmembrane 4 L six family member 1 0.00979256
CRABP2 cellular retinoic acid binding protein 2 0.00976495
SIRT3 sirtuin 3 0.00966495
TRIM29 tripartite motif containing 29 0.00960432
ADIRF adipogenesis regulatory factor 0.00941294
PEG10 paternally expressed 10 0.00921999
CCN2 cellular communication network factor 2 0.0091463
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00913563
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00892467
PBX3 pre-B-cell leukemia homeobox 3 0.0089245
NEBL nebulette 0.00884056
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00883492
GPX2 glutathione peroxidase 2 0.00883285
PELI1 pellino E3 ubiquitin protein ligase 1 0.0085772
S100A2 S100 calcium binding protein A2 0.00817862
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00811855
MAP7 microtubule-associated protein 7 0.00802537
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00793487
DEFB1 defensin, beta 1 0.00789682
TLR4 toll-like receptor 4 0.00778414
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.00761583
JADE3 jade family PHD finger 3 0.00748191
GSTP1 glutathione S-transferase pi 1 0.00740749
BGN biglycan 0.00734928
C9ORF3 chromosome 9 open reading frame 3 0.00734688
KRT5 keratin 5, type II 0.00729872
TFPI2 tissue factor pathway inhibitor 2 0.0072904
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00725363
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00724939
PTK2B protein tyrosine kinase 2 beta 0.00723743
TNS3 tensin 3 0.00720175
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00718371
ZBED2 zinc finger, BED-type containing 2 0.00712506
NOTCH1 notch 1 0.00707161
SH3BP4 SH3-domain binding protein 4 0.00693682
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.00693504
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00691101
SIK1 salt-inducible kinase 1 0.00689297
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00684898
TTC39A tetratricopeptide repeat domain 39A 0.00676873
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00675583
CLDN10 claudin 10 0.00671585
EHD3 EH-domain containing 3 0.00671539
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00669949
FRMD4B FERM domain containing 4B 0.00669334
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00664819
AUTS2 autism susceptibility candidate 2 0.00662429
FGFBP1 fibroblast growth factor binding protein 1 0.00662246
HOXC10 homeobox C10 0.00657429
CTBP2 C-terminal binding protein 2 0.00655473
PERP PERP, TP53 apoptosis effector 0.00652588
IPO13 importin 13 0.0065228
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00651759
KLF5 Kruppel-like factor 5 (intestinal) 0.00649516
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00649504
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.0064726
CBX1 chromobox homolog 1 0.00646947
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00645072
KCTD12 potassium channel tetramerization domain containing 12 0.00644371
COL16A1 collagen, type XVI, alpha 1 0.00641629
GAB2 GRB2-associated binding protein 2 0.00641048
PCDH9 protocadherin 9 0.00639385
SOCS2 suppressor of cytokine signaling 2 0.0063449
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00633086
KLK7 kallikrein-related peptidase 7 0.00630402
INHBA inhibin, beta A 0.00629264
EFHD1 EF-hand domain family, member D1 0.00625189
MTUS1 microtubule associated tumor suppressor 1 0.00623875
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.00620178
WNK1 WNK lysine deficient protein kinase 1 0.00616893
RHCG Rh family, C glycoprotein 0.00612129
DHCR24 24-dehydrocholesterol reductase 0.00610712
FBXL7 F-box and leucine-rich repeat protein 7 0.00607027
FERMT1 fermitin family member 1 0.0060513
CALML3 calmodulin-like 3 0.0060331
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00601868
SQLE squalene epoxidase 0.00601818
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00601717
ZNF185 zinc finger protein 185 (LIM domain) 0.00598576
NAV2 neuron navigator 2 0.00598466
LGALS4 lectin, galactoside-binding, soluble, 4 0.00597548
EHF ets homologous factor 0.00597346
MYO5C myosin VC 0.00597104
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00594691
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.00592548
RFTN1 raftlin, lipid raft linker 1 0.00589712
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00588816
AKR1C2 aldo-keto reductase family 1, member C2 0.00587969
WDR7 WD repeat domain 7 0.00587359
FGFR3 fibroblast growth factor receptor 3 0.00584866
AREG amphiregulin 0.00584589
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00584367
MAL mal, T-cell differentiation protein 0.00582147
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00580834
WASL Wiskott-Aldrich syndrome-like 0.00579666
CHD4 chromodomain helicase DNA binding protein 4 0.00576127
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00573408
CA12 carbonic anhydrase XII 0.00572502
DYNLL1 dynein, light chain, LC8-type 1 0.00572235
SGCE sarcoglycan, epsilon 0.0057022
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00568753
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 0.00567628
KRT6A keratin 6A, type II 0.00567195
EPS8L2 EPS8-like 2 0.00566254
MID1 midline 1 0.00562002
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00559862
AGTR1 angiotensin II receptor, type 1 0.00559821
BHLHE41 basic helix-loop-helix family, member e41 0.00559465
TXN thioredoxin 0.00558761
S100A14 S100 calcium binding protein A14 0.00558423
SETBP1 SET binding protein 1 0.00556938
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00556776
TCTA T-cell leukemia translocation altered 0.00556081
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00552527
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00552497
HIST1H2BD histone cluster 1, H2bd 0.00551954
SH3YL1 SH3 and SYLF domain containing 1 0.00550308
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00549313
PNN pinin, desmosome associated protein 0.00548481
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00547637
KRT6B keratin 6B, type II 0.00546832
AMOTL2 angiomotin like 2 0.00546502
FAM120A family with sequence similarity 120A 0.00544937
SPRR1B small proline-rich protein 1B 0.00544534
TP53I3 tumor protein p53 inducible protein 3 0.00544097
KAZN kazrin, periplakin interacting protein 0.00541709
IGFBP5 insulin-like growth factor binding protein 5 0.00539307
CTNND1 catenin (cadherin-associated protein), delta 1 0.00537638
ADGRF5 adhesion G protein-coupled receptor F5 0.00536742
IL17RB interleukin 17 receptor B 0.00535788
NSF N-ethylmaleimide-sensitive factor 0.0053491
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.00534198
EGF epidermal growth factor 0.00533183
DPYSL2 dihydropyrimidinase-like 2 0.00533167
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00532507
NCF1C neutrophil cytosolic factor 1C pseudogene 0.00531439
ESRP1 epithelial splicing regulatory protein 1 0.00529405
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00529016
MCTP2 multiple C2 domains, transmembrane 2 0.00526352
TPPP3 tubulin polymerization-promoting protein family member 3 0.00524639
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00524448
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.00520624
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00519957
CTSD cathepsin D 0.00519368
AKR1C3 aldo-keto reductase family 1, member C3 0.00519246
DTX4 deltex 4, E3 ubiquitin ligase 0.00518957
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00518708
BHMT betaine--homocysteine S-methyltransferase 0.00517912
TMEM131L transmembrane 131 like 0.00517095
ACAA2 acetyl-CoA acyltransferase 2 0.00516909
KRT16 keratin 16, type I 0.00515949
PDGFD platelet derived growth factor D 0.0051528
EXT1 exostosin glycosyltransferase 1 0.00515065
SIX1 SIX homeobox 1 0.00513583
AKR1C1 aldo-keto reductase family 1, member C1 0.00512061
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00511867
DNMBP dynamin binding protein 0.00511303
UBA1 ubiquitin-like modifier activating enzyme 1 0.0051122
RAB25 RAB25, member RAS oncogene family 0.00509933
WARS1 tryptophanyl-tRNA synthetase 1 0.0050975
UNC13B unc-13 homolog B (C. elegans) 0.0050957
EXPH5 exophilin 5 0.00509263
KIF13B kinesin family member 13B 0.00506719
NT5E 5'-nucleotidase, ecto (CD73) 0.00506412
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0050524
IGFBP4 insulin-like growth factor binding protein 4 0.00504936
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00504013
KLF7 Kruppel-like factor 7 (ubiquitous) 0.00503669
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00501241
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.00500489
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00499742
SCPEP1 serine carboxypeptidase 1 0.00499641
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.00497279
OSBPL1A oxysterol binding protein-like 1A 0.00496882
DPEP1 dipeptidase 1 (renal) 0.00495523
MUC16 mucin 16, cell surface associated 0.00495352
PCOLCE procollagen C-endopeptidase enhancer 0.00494727
KRT23 keratin 23, type I 0.00492219
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 0.00492005
NDRG1 N-myc downstream regulated 1 0.00491348
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00490162
GAS6 growth arrest-specific 6 0.00490125
FYN FYN proto-oncogene, Src family tyrosine kinase 0.00488722
FBN2 fibrillin 2 0.00488693
IGF1R insulin-like growth factor 1 receptor 0.00487585
LRRC32 leucine rich repeat containing 32 0.00487451
NEFM neurofilament, medium polypeptide 0.00486518
MET MET proto-oncogene, receptor tyrosine kinase 0.0048572
CYB5R2 cytochrome b5 reductase 2 0.00485663
AHNAK AHNAK nucleoprotein 0.00485471
MYO1B myosin IB 0.0048433
PRODH proline dehydrogenase (oxidase) 1 0.00483855
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00483429
THY1 Thy-1 cell surface antigen 0.0048326
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00482674
SFTPA2 surfactant protein A2 0.00477408
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00477191
LAMP5 lysosomal-associated membrane protein family, member 5 0.00475218
BCAS1 breast carcinoma amplified sequence 1 0.00474868
HAO2 hydroxyacid oxidase 2 (long chain) 0.00474815
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.00474736
PLXND1 plexin D1 0.00472353
AK1 adenylate kinase 1 0.00471314
LAMB1 laminin, beta 1 0.00470091
SPRR1A small proline-rich protein 1A 0.0046953
E2F2 E2F transcription factor 2 0.00468958
STS steroid sulfatase (microsomal), isozyme S 0.00468719
ESRP2 epithelial splicing regulatory protein 2 0.00467795
NADSYN1 NAD synthetase 1 0.00466655
IQSEC1 IQ motif and Sec7 domain 1 0.00466308
KIAA0930 KIAA0930 0.00464271
CTSZ cathepsin Z 0.00464067
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00463718
ALOX5 arachidonate 5-lipoxygenase 0.00463217
LRP2 low density lipoprotein receptor-related protein 2 0.00462646
RGCC regulator of cell cycle 0.00462248
CALB1 calbindin 1, 28kDa 0.00461229
STK38 serine/threonine kinase 38 0.00460366
CUL3 cullin 3 0.00460029
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.00459778
UGT8 UDP glycosyltransferase 8 0.00459268
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.00457803
TMEM176B transmembrane protein 176B 0.00457555
ADGRL2 adhesion G protein-coupled receptor L2 0.00456517
ACAT1 acetyl-CoA acetyltransferase 1 0.00456291
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00456183
IRAK1 interleukin-1 receptor-associated kinase 1 0.00453928
HSPA1A heat shock 70kDa protein 1A 0.0045377
BTK Bruton agammaglobulinemia tyrosine kinase 0.00453589
PRTN3 proteinase 3 0.00453317
CIT citron rho-interacting serine/threonine kinase 0.00452715
COL9A3 collagen, type IX, alpha 3 0.00452615
STAP2 signal transducing adaptor family member 2 0.00450146
HYAL1 hyaluronoglucosaminidase 1 0.00449823
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.00449709
UMOD uromodulin 0.00449486
AEBP1 AE binding protein 1 0.00449041
WNT5B wingless-type MMTV integration site family, member 5B 0.00448774
PXDN peroxidasin 0.00448315
DAPK1 death-associated protein kinase 1 0.00446869
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00445924
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.00445792
TFCP2L1 transcription factor CP2-like 1 0.00445719
EIF6 eukaryotic translation initiation factor 6 0.00443163

decreased expression

Symbol Name Standardized Value
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0137029
NIBAN1 niban apoptosis regulator 1 -0.0117888
CD36 CD36 molecule (thrombospondin receptor) -0.0112591
JCHAIN joining chain of multimeric IgA and IgM -0.0111191
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0110548
KLRB1 killer cell lectin-like receptor subfamily B, member 1 -0.0106239
EIF5A eukaryotic translation initiation factor 5A -0.0102449
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.00980197
PRDX2 peroxiredoxin 2 -0.00979667
LTF lactotransferrin -0.00958179
CD48 CD48 molecule -0.00950425
C3 complement component 3 -0.00944792
CHI3L2 chitinase 3-like 2 -0.00936773
C1S complement component 1, s subcomponent -0.00926855
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00920619
CST3 cystatin C -0.0089886
C1R complement component 1, r subcomponent -0.00895649
IL7R interleukin 7 receptor -0.00889951
NELL2 NEL-like 2 (chicken) -0.00888136
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00873073
COL4A5 collagen, type IV, alpha 5 -0.00866854
CCNB1 cyclin B1 -0.0086254
IFI6 interferon, alpha-inducible protein 6 -0.00858958
LXN latexin -0.00843219
TSPAN13 tetraspanin 13 -0.00836524
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00798313
CHRDL1 chordin-like 1 -0.00789804
CD2 CD2 molecule -0.00775341
SUB1 SUB1 homolog (S. cerevisiae) -0.00763447
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00759146
NTS neurotensin -0.00753589
COL6A2 collagen, type VI, alpha 2 -0.00746687
MMP1 matrix metallopeptidase 1 -0.00743527
ATF3 activating transcription factor 3 -0.00739784
CA2 carbonic anhydrase II -0.00739292
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00734183
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00725094
METRN meteorin, glial cell differentiation regulator -0.00720277
SPARCL1 SPARC-like 1 (hevin) -0.00718631
ADIPOQ adiponectin, C1Q and collagen domain containing -0.00716332
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00714933
BCHE butyrylcholinesterase -0.00713732
GPX3 glutathione peroxidase 3 -0.00711212
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00709191
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00704485
ITM2A integral membrane protein 2A -0.0070177
FYB1 FYN binding protein 1 -0.00699067
CD99 CD99 molecule -0.00698561
TNIK TRAF2 and NCK interacting kinase -0.00698139
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00696967
GYPC glycophorin C (Gerbich blood group) -0.00696618
PDLIM3 PDZ and LIM domain 3 -0.00696485
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -0.00694809
FABP6 fatty acid binding protein 6, ileal -0.00694736
SLC38A2 solute carrier family 38, member 2 -0.00694554
MT1M metallothionein 1M -0.00688178
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00686529
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.00686305
DES desmin -0.0068214
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00679775
S100B S100 calcium binding protein B -0.00679653
MOCOS molybdenum cofactor sulfurase -0.00677745
LTBP2 latent transforming growth factor beta binding protein 2 -0.00671608
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00670926
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00670067
ADA adenosine deaminase -0.00668787
ELOVL5 ELOVL fatty acid elongase 5 -0.00664489
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00661768
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00659306
DLK1 delta-like 1 homolog (Drosophila) -0.0065557
SFRP1 secreted frizzled-related protein 1 -0.00650251
SOD2 superoxide dismutase 2, mitochondrial -0.00647158
CCL5 chemokine (C-C motif) ligand 5 -0.00646995
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00640001
ADAMDEC1 ADAM-like, decysin 1 -0.00637038
ADAT1 adenosine deaminase, tRNA-specific 1 -0.0063596
BST2 bone marrow stromal cell antigen 2 -0.00634959
FABP7 fatty acid binding protein 7, brain -0.00632415
CD300A CD300a molecule -0.00630602
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00629677
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00627063
CD164 CD164 molecule, sialomucin -0.00625824
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.00622874
LGMN legumain -0.00622683
TMEM14B transmembrane protein 14B -0.0062256
RRM2 ribonucleotide reductase M2 -0.00621952
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00621038
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00619004
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00615792
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00614202
IL6 interleukin 6 -0.00613653
SELL selectin L -0.00612607
NDN necdin, melanoma antigen (MAGE) family member -0.00611338
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00609016
NES nestin -0.00608312
WTAP Wilms tumor 1 associated protein -0.00608248
ITK IL2-inducible T-cell kinase -0.00607795
CPVL carboxypeptidase, vitellogenic-like -0.00607402
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0060731
WASHC4 WASH complex subunit 4 -0.00605752
ACTN1 actinin, alpha 1 -0.00604541
SNX10 sorting nexin 10 -0.00602638
NRN1 neuritin 1 -0.00602355
OSTM1 osteopetrosis associated transmembrane protein 1 -0.00599106
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00598668
FBXO11 F-box protein 11 -0.00598149
LYZ lysozyme -0.00597978
GLIPR1 GLI pathogenesis-related 1 -0.0059544
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00594717
TSC22D1 TSC22 domain family, member 1 -0.00592764
SCD5 stearoyl-CoA desaturase 5 -0.00590816
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00590755
EVI2A ecotropic viral integration site 2A -0.00587493
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00587452
CD53 CD53 molecule -0.00586397
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00579357
AMD1 adenosylmethionine decarboxylase 1 -0.00577852
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00576174
RSL24D1 ribosomal L24 domain containing 1 -0.00575957
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00573071
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00572228
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00568316
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.00563863
GPX1 glutathione peroxidase 1 -0.00563761
ZNF91 zinc finger protein 91 -0.00563365
RPL36 ribosomal protein L36 -0.0056262
HHEX hematopoietically expressed homeobox -0.00562547
TMX1 thioredoxin-related transmembrane protein 1 -0.00560806
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00559818
GPR65 G protein-coupled receptor 65 -0.00558823
NDFIP1 Nedd4 family interacting protein 1 -0.00558118
GTPBP8 GTP-binding protein 8 (putative) -0.00558047
FABP4 fatty acid binding protein 4, adipocyte -0.00557345
NPY1R neuropeptide Y receptor Y1 -0.00555149
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00553684
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.00553635
SDF4 stromal cell derived factor 4 -0.00552837
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.0055072
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00548099
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.00547486
CENPU centromere protein U -0.00546314
STXBP2 syntaxin binding protein 2 -0.0054182
NMU neuromedin U -0.00541516
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00539574
CNR1 cannabinoid receptor 1 (brain) -0.00539283
SELENOF selenoprotein F -0.00538763
CNTN1 contactin 1 -0.00537797
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.00537024
ACTB actin, beta -0.00536493
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00534633
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00534024
CD163 CD163 molecule -0.00533015
CIDEC cell death-inducing DFFA-like effector c -0.00532936
PLP1 proteolipid protein 1 -0.00532895
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -0.00531455
RNF130 ring finger protein 130 -0.00529799
AKAP7 A kinase (PRKA) anchor protein 7 -0.00528127
MPO myeloperoxidase -0.00527762
HLA-DRA major histocompatibility complex, class II, DR alpha -0.00527525
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00523546
SPON2 spondin 2, extracellular matrix protein -0.0052352
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00522229
GSDME gasdermin E -0.00522207
PTPRM protein tyrosine phosphatase, receptor type, M -0.00521712
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -0.00521526
HBB hemoglobin, beta -0.005214
ACTN2 actinin, alpha 2 -0.00520544
WBP5 WW domain binding protein 5 -0.00519435
GZMK granzyme K (granzyme 3; tryptase II) -0.00515783
ARHGAP15 Rho GTPase activating protein 15 -0.0051573
S100A7 S100 calcium binding protein A7 -0.00515679
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00515428
IL2RB interleukin 2 receptor, beta -0.00513956
MIS12 MIS12 kinetochore complex component -0.00513936
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -0.00512931
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00511778
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.005112
NCAM1 neural cell adhesion molecule 1 -0.0051022
PMP22 peripheral myelin protein 22 -0.00510153
SI sucrase-isomaltase (alpha-glucosidase) -0.00509993
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A -0.00509667
RAD23B RAD23 homolog B (S. cerevisiae) -0.00509228
CRBN cereblon -0.00509119
PLIN1 perilipin 1 -0.00508711
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00508652
BIRC5 baculoviral IAP repeat containing 5 -0.00507489
ITGB1BP1 integrin beta 1 binding protein 1 -0.00506529
ERP29 endoplasmic reticulum protein 29 -0.00506161
TXNDC9 thioredoxin domain containing 9 -0.00505857
CA14 carbonic anhydrase XIV -0.00504203
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.00503126
LOX lysyl oxidase -0.00502261
RPA2 replication protein A2, 32kDa -0.00501819
TXK TXK tyrosine kinase -0.0050139
CASP8 caspase 8, apoptosis-related cysteine peptidase -0.00499416
KRT19 keratin 19, type I -0.00499384
MDK midkine (neurite growth-promoting factor 2) -0.00498232
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00496437
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00495499
REEP1 receptor accessory protein 1 -0.00495404
SOX11 SRY (sex determining region Y)-box 11 -0.00494315
S100A8 S100 calcium binding protein A8 -0.00492096
STK17A serine/threonine kinase 17a -0.0049193
EXOSC8 exosome component 8 -0.00491801
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 -0.00491104
BAG2 BCL2-associated athanogene 2 -0.00490907
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00490656
PBX1 pre-B-cell leukemia homeobox 1 -0.00490507
CFB complement factor B -0.00489868
APOB apolipoprotein B -0.00489194
MREG melanoregulin -0.00488222
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00487659
A2M alpha-2-macroglobulin -0.00487607
SLN sarcolipin -0.00487542
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00487521
HSPA13 heat shock protein 70kDa family, member 13 -0.00487205
SLC30A10 solute carrier family 30, member 10 -0.00486355
CNIH3 cornichon family AMPA receptor auxiliary protein 3 -0.0048618
MEX3D mex-3 RNA binding family member D -0.00484294
C6ORF48 chromosome 6 open reading frame 48 -0.00483886
CHP1 calcineurin-like EF-hand protein 1 -0.00483318
TMOD1 tropomodulin 1 -0.00479752
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00479638
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.0047947
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -0.00478998
IER2 immediate early response 2 -0.00478423
IL13RA2 interleukin 13 receptor, alpha 2 -0.00477743
MMD monocyte to macrophage differentiation-associated -0.00476186
CDC42SE1 CDC42 small effector 1 -0.00475772
LYRM4 LYR motif containing 4 -0.00475402
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.00473722
C6ORF62 chromosome 6 open reading frame 62 -0.00473648
SCG5 secretogranin V -0.00471077
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00470527
ADGRL3 adhesion G protein-coupled receptor L3 -0.00470271
ERBIN erbb2 interacting protein -0.00468604
IL24 interleukin 24 -0.00467691
PLIN2 perilipin 2 -0.00467402
LAPTM5 lysosomal protein transmembrane 5 -0.00467317
SYNM synemin, intermediate filament protein -0.00467235
UBE2S ubiquitin-conjugating enzyme E2S -0.0046723
PECR peroxisomal trans-2-enoyl-CoA reductase -0.00467228
TMEM126B transmembrane protein 126B -0.00467034
GSTO1 glutathione S-transferase omega 1 -0.00466724
SORBS1 sorbin and SH3 domain containing 1 -0.00466534
FBXO5 F-box protein 5 -0.0046638
KLHDC3 kelch domain containing 3 -0.00466224
DEK DEK proto-oncogene -0.00465051
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.00463996
MCUB mitochondrial calcium uniporter dominant negative subunit beta -0.00463188