PKNOX2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description PBX/knotted 1 homeobox 2|Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009] (NCBI Entrez Gene Database, 63876)
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Genes

27 target genes of the PKNOX2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ASB15 ankyrin repeat and SOCS box containing 15
ASCL5 achaete-scute family bHLH transcription factor 5
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
CDC20 cell division cycle 20
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding)
FAM172A family with sequence similarity 172, member A
HOXD3 homeobox D3
LGALSL lectin, galactoside-binding-like
LHX9 LIM homeobox 9
LIMCH1 LIM and calponin homology domains 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MBD6 methyl-CpG binding domain protein 6
MYLK2 myosin light chain kinase 2
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
R3HCC1 R3H domain and coiled-coil containing 1
RB1 retinoblastoma 1
SREBF2 sterol regulatory element binding transcription factor 2
TEF thyrotrophic embryonic factor
TMEM35 transmembrane protein 35
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
USP15 ubiquitin specific peptidase 15
WWC1 WW and C2 domain containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZFHX4 zinc finger homeobox 4
ZNRD1 zinc ribbon domain containing 1