PL45 Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: ductal adenocarcinoma; same patient as Panc 10.05 cells (Cell Line Ontology, CLO_0008454)
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Genes

209 genes with high or low expression in PL45 relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 3.08893
LIPA lipase A, lysosomal acid, cholesterol esterase 2.80966
CYSRT1 cysteine-rich tail protein 1 2.70009
TMUB2 transmembrane and ubiquitin-like domain containing 2 2.62246
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.40848
SPOP speckle-type POZ protein 2.35746
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.35622
CST6 cystatin E/M 2.17222
SAV1 salvador family WW domain containing protein 1 2.13434
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 2.12398
SCGB1C1 secretoglobin, family 1C, member 1 2.06275
NPBWR2 neuropeptides B/W receptor 2 1.99616
RFPL2 ret finger protein-like 2 1.98997
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1.94152
LOC285889 uncharacterized LOC285889 1.93849
FKBP1A FK506 binding protein 1A, 12kDa 1.93732
SP2 Sp2 transcription factor 1.92589
DPY19L2P3 DPY19L2 pseudogene 3 1.91272
AGFG2 ArfGAP with FG repeats 2 1.90645
PDK2 pyruvate dehydrogenase kinase, isozyme 2 1.90381
LRRC61 leucine rich repeat containing 61 1.89051
UCA1 urothelial cancer associated 1 (non-protein coding) 1.88444
TRIM14 tripartite motif containing 14 1.85871
MRPL27 mitochondrial ribosomal protein L27 1.84278
PHB prohibitin 1.83394
LRRC57 leucine rich repeat containing 57 1.83247
XPA xeroderma pigmentosum, complementation group A 1.82939
PHF19 PHD finger protein 19 1.81992
LRRC59 leucine rich repeat containing 59 1.81671
DHDH dihydrodiol dehydrogenase (dimeric) 1.81424
KRTAP3-2 keratin associated protein 3-2 1.79958
CCDC43 coiled-coil domain containing 43 1.79339
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.79086
DUSP14 dual specificity phosphatase 14 1.76874
MLX MLX, MAX dimerization protein 1.74778
IAPP islet amyloid polypeptide 1.74544
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.74086
LINC00458 long intergenic non-protein coding RNA 458 1.73047
WFDC2 WAP four-disulfide core domain 2 1.71811
IFNB1 interferon, beta 1, fibroblast 1.71661
IFI35 interferon-induced protein 35 1.71548
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.7134
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.7059
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 1.70536
C19ORF18 chromosome 19 open reading frame 18 1.69291
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.68634
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 1.67833
TSSC1 tumor suppressing subtransferable candidate 1 1.65724
RPE ribulose-5-phosphate-3-epimerase 1.65075
ARHGAP23 Rho GTPase activating protein 23 1.64976
HOXB7 homeobox B7 1.64295
OASL 2'-5'-oligoadenylate synthetase-like 1.64135
NANOS1 nanos homolog 1 (Drosophila) 1.6394
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.63671
EPHX3 epoxide hydrolase 3 1.6166
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 1.61631
CDC14B cell division cycle 14B 1.60504
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 1.59485
MRGPRX2 MAS-related GPR, member X2 1.59454
SNTN sentan, cilia apical structure protein 1.58119
TMEM18 transmembrane protein 18 1.57811
MYH16 myosin, heavy chain 16 pseudogene 1.57492
ADRB2 adrenoceptor beta 2, surface 1.57251
MTAP methylthioadenosine phosphorylase 1.56071
LOC286059 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain pseudogene 1.5585
SMIM7 small integral membrane protein 7 1.55246
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.52682
MYO19 myosin XIX 1.52392
SLC35B1 solute carrier family 35, member B1 1.51525
CCDC152 coiled-coil domain containing 152 1.50517
POLM polymerase (DNA directed), mu 1.49013
IFIH1 interferon induced with helicase C domain 1 1.48813
RAB5C RAB5C, member RAS oncogene family 1.48502
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 1.47481
ACP1 acid phosphatase 1, soluble 1.47043
C15ORF48 chromosome 15 open reading frame 48 1.46903
CSN3 casein kappa 1.46142
TMEM55B transmembrane protein 55B 1.4542
PROSER2 proline and serine rich 2 1.45286
LINC00472 long intergenic non-protein coding RNA 472 1.44672
ANKRD40 ankyrin repeat domain 40 1.44577
FNIP1 folliculin interacting protein 1 1.44119
ALOX12B arachidonate 12-lipoxygenase, 12R type 1.42338
CDK12 cyclin-dependent kinase 12 1.42337
ODF3L1 outer dense fiber of sperm tails 3-like 1 1.42274
MED1 mediator complex subunit 1 1.42168
INSIG2 insulin induced gene 2 1.41132
MYOF myoferlin 1.40818
ZNF557 zinc finger protein 557 1.40664
TICAM1 toll-like receptor adaptor molecule 1 1.40345
ACSF2 acyl-CoA synthetase family member 2 1.40073
SH3YL1 SH3 and SYLF domain containing 1 1.39955
GJB3 gap junction protein, beta 3, 31kDa 1.39578
FOXL1 forkhead box L1 1.39392
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 1.39309
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 1.39008
OBP2B odorant binding protein 2B 1.3888
EPN3 epsin 3 1.38322
RBMS2 RNA binding motif, single stranded interacting protein 2 1.38222
ASNSD1 asparagine synthetase domain containing 1 1.37752
NBR1 neighbor of BRCA1 gene 1 1.37533
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 1.37467
TRIM42 tripartite motif containing 42 1.37014
ISCA2 iron-sulfur cluster assembly 2 1.36993
TMEM171 transmembrane protein 171 1.36456
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 1.36336
TRIM29 tripartite motif containing 29 1.36251
MAP2K1 mitogen-activated protein kinase kinase 1 1.36248
SMIM15 small integral membrane protein 15 1.36144
RSAD2 radical S-adenosyl methionine domain containing 2 1.36078
HEXIM1 hexamethylene bis-acetamide inducible 1 1.35994
LOC440434 aminopeptidase puromycin sensitive pseudogene 1.35337
PTRH2 peptidyl-tRNA hydrolase 2 1.3491

low expression

Symbol Name Standardized Value
STX8 syntaxin 8 -2.94276
ANKRD54 ankyrin repeat domain 54 -2.49487
OTUD3 OTU deubiquitinase 3 -2.48636
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -2.38241
PHF8 PHD finger protein 8 -2.29682
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.20989
FAM167A-AS1 FAM167A antisense RNA 1 -2.16449
AWAT1 acyl-CoA wax alcohol acyltransferase 1 -2.16415
KDM2B lysine (K)-specific demethylase 2B -2.15258
WDR63 WD repeat domain 63 -2.10477
SYN3 synapsin III -2.09398
OR8D2 olfactory receptor, family 8, subfamily D, member 2 (gene/pseudogene) -2.06473
COX11 COX11 cytochrome c oxidase copper chaperone -2.02576
CYTL1 cytokine-like 1 -2.02258
BLMH bleomycin hydrolase -2.01811
DVL3 dishevelled segment polarity protein 3 -1.98902
FGR FGR proto-oncogene, Src family tyrosine kinase -1.98417
OSTC oligosaccharyltransferase complex subunit (non-catalytic) -1.95949
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -1.95417
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -1.94417
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain -1.93839
LOC100133039 uncharacterized LOC100133039 -1.93671
CABIN1 calcineurin binding protein 1 -1.93206
SESN2 sestrin 2 -1.92791
SH3GL3 SH3-domain GRB2-like 3 -1.89034
TMEM221 transmembrane protein 221 -1.88511
TNRC18 trinucleotide repeat containing 18 -1.88431
B3GAT3 beta-1,3-glucuronyltransferase 3 -1.87862
ZSWIM2 zinc finger, SWIM-type containing 2 -1.85277
EVL Enah/Vasp-like -1.8515
RNF8 ring finger protein 8, E3 ubiquitin protein ligase -1.83947
ZNF248 zinc finger protein 248 -1.83791
EP300 E1A binding protein p300 -1.82872
WDR25 WD repeat domain 25 -1.81218
ARIH2OS ariadne homolog 2 opposite strand -1.79438
USP48 ubiquitin specific peptidase 48 -1.78983
PITPNA phosphatidylinositol transfer protein, alpha -1.78874
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -1.77486
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -1.77131
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -1.76092
USP33 ubiquitin specific peptidase 33 -1.75669
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -1.75491
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) -1.74834
TREX2 three prime repair exonuclease 2 -1.74438
RLBP1 retinaldehyde binding protein 1 -1.74167
EMX2 empty spiracles homeobox 2 -1.74042
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.73992
MARK3 MAP/microtubule affinity-regulating kinase 3 -1.7215
PRR18 proline rich 18 -1.69142
TOP2B topoisomerase (DNA) II beta 180kDa -1.69126
PDGFRB platelet-derived growth factor receptor, beta polypeptide -1.68716
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.67359
MRPS23 mitochondrial ribosomal protein S23 -1.6618
SH3PXD2B SH3 and PX domains 2B -1.64462
INPPL1 inositol polyphosphate phosphatase-like 1 -1.64335
C1ORF86 chromosome 1 open reading frame 86 -1.62858
RAP2A RAP2A, member of RAS oncogene family -1.62697
TMEM167B transmembrane protein 167B -1.62158
AQP7 aquaporin 7 -1.61791
ZNF25 zinc finger protein 25 -1.61086
GLUD2 glutamate dehydrogenase 2 -1.60681
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 -1.59409
SRPRB signal recognition particle receptor, B subunit -1.59285
TCAIM T cell activation inhibitor, mitochondrial -1.58787
ZNF18 zinc finger protein 18 -1.57563
CCDC176 coiled-coil domain containing 176 -1.56724
MIB1 mindbomb E3 ubiquitin protein ligase 1 -1.56538
CNOT6L CCR4-NOT transcription complex, subunit 6-like -1.56302
SUCNR1 succinate receptor 1 -1.5581
P3H1 prolyl 3-hydroxylase 1 -1.55664
MARCKSL1 MARCKS-like 1 -1.5556
KCTD15 potassium channel tetramerization domain containing 15 -1.5554
LSMEM1 leucine-rich single-pass membrane protein 1 -1.5551
ADGRA2 adhesion G protein-coupled receptor A2 -1.53832
TIMD4 T-cell immunoglobulin and mucin domain containing 4 -1.53483
NNT nicotinamide nucleotide transhydrogenase -1.53009
AGO3 argonaute RISC catalytic component 3 -1.52933
FAM175A family with sequence similarity 175, member A -1.52929
C21ORF33 chromosome 21 open reading frame 33 -1.51232
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 -1.50826
CDPF1 cysteine-rich, DPF motif domain containing 1 -1.50341
LOC100129935 lectin, galactoside-binding, soluble, 14 pseudogene -1.49931
XCR1 chemokine (C motif) receptor 1 -1.49864
ZNF518B zinc finger protein 518B -1.49815
RAB33B RAB33B, member RAS oncogene family -1.49699
ULBP1 UL16 binding protein 1 -1.49547
PBRM1 polybromo 1 -1.49003
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.47683
CLCC1 chloride channel CLIC-like 1 -1.47618
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -1.46913
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -1.46907
LINC00294 long intergenic non-protein coding RNA 294 -1.46737
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 -1.46493
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -1.46344
EFHC1 EF-hand domain (C-terminal) containing 1 -1.45707
TCEAL3 transcription elongation factor A (SII)-like 3 -1.4559