PLA2G1B Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description phospholipase A2, group IB (pancreas)|This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 5319)
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7 interacting proteins for PLA2G1B from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BGN biglycan
CSF3R colony stimulating factor 3 receptor (granulocyte)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAA phospholipase A2-activating protein
SOCS2 suppressor of cytokine signaling 2