PLAGL1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description pleiomorphic adenoma gene-like 1|This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010] (NCBI Entrez Gene Database, 5325)
External Link https://ncbi.nlm.nih.gov/gene/5325
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Genes

498 genes differentially expressed following the PLAGL1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAS GNAS complex locus 0.0155112
TMSB15A thymosin beta 15a 0.0148324
ADIRF adipogenesis regulatory factor 0.0139627
ADI1 acireductone dioxygenase 1 0.0135423
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0112919
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.011125
MAGEA3 melanoma antigen family A3 0.0108984
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.0108381
AQP3 aquaporin 3 (Gill blood group) 0.0107903
DHCR24 24-dehydrocholesterol reductase 0.0103585
KRT18 keratin 18, type I 0.0102921
PRDX2 peroxiredoxin 2 0.0102602
NDNF neuron-derived neurotrophic factor 0.0100807
FGG fibrinogen gamma chain 0.0100591
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0100496
NRGN neurogranin (protein kinase C substrate, RC3) 0.00997433
SC5D sterol-C5-desaturase 0.00990576
FRY furry homolog (Drosophila) 0.00987617
CP ceruloplasmin (ferroxidase) 0.00964362
FBP1 fructose-1,6-bisphosphatase 1 0.00948285
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0093661
S100A4 S100 calcium binding protein A4 0.00923596
S100A2 S100 calcium binding protein A2 0.00904968
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00904352
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00897458
ARG2 arginase 2 0.00878721
DEFB1 defensin, beta 1 0.00878668
ADGRF5 adhesion G protein-coupled receptor F5 0.0087786
RPA3 replication protein A3, 14kDa 0.00876802
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00867964
ARHGAP29 Rho GTPase activating protein 29 0.00854829
ACAT2 acetyl-CoA acetyltransferase 2 0.00853289
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00840217
GPC3 glypican 3 0.00833909
ANPEP alanyl (membrane) aminopeptidase 0.00831464
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00831176
PIP prolactin-induced protein 0.00827694
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00817385
METTL7A methyltransferase like 7A 0.00812734
EDNRA endothelin receptor type A 0.00812561
NUSAP1 nucleolar and spindle associated protein 1 0.00808568
C7 complement component 7 0.00806495
SLPI secretory leukocyte peptidase inhibitor 0.00802756
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00797796
TFPI2 tissue factor pathway inhibitor 2 0.00796559
NFIB nuclear factor I/B 0.00795603
TSPYL5 TSPY-like 5 0.00791056
ACP3 acid phosphatase 3 0.00788764
DOCK4 dedicator of cytokinesis 4 0.0078836
TOX3 TOX high mobility group box family member 3 0.00786861
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.00785256
GIMAP6 GTPase, IMAP family member 6 0.00785086
PPARG peroxisome proliferator-activated receptor gamma 0.00781029
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00780232
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0077668
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00776067
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00769131
NELL1 NEL-like 1 (chicken) 0.00765884
SFTPC surfactant protein C 0.00763464
GSTM3 glutathione S-transferase mu 3 (brain) 0.00762818
F5 coagulation factor V (proaccelerin, labile factor) 0.00756805
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00752059
GSTA1 glutathione S-transferase alpha 1 0.00750695
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00747315
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00746945
GATA2 GATA binding protein 2 0.00742239
NMU neuromedin U 0.0073489
SFTPD surfactant protein D 0.00734715
CSAD cysteine sulfinic acid decarboxylase 0.00734259
NPY1R neuropeptide Y receptor Y1 0.00727032
CKS1B CDC28 protein kinase regulatory subunit 1B 0.00722838
ADARB1 adenosine deaminase, RNA-specific, B1 0.0072049
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00717293
NPTX2 neuronal pentraxin II 0.0071449
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00713787
THBD thrombomodulin 0.0071212
C5AR1 complement component 5a receptor 1 0.00711938
CXADR coxsackie virus and adenovirus receptor 0.00711161
C4BPA complement component 4 binding protein, alpha 0.00709436
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.00705663
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00704969
IRAK3 interleukin-1 receptor-associated kinase 3 0.00703584
GTF2I general transcription factor IIi 0.00701676
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00700634
TACSTD2 tumor-associated calcium signal transducer 2 0.00698003
PDGFC platelet derived growth factor C 0.00696825
ZCCHC14 zinc finger, CCHC domain containing 14 0.0069648
SPTSSA serine palmitoyltransferase, small subunit A 0.00695621
BTG3 BTG family, member 3 0.00694334
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.00693544
FASN fatty acid synthase 0.00692628
DPYD dihydropyrimidine dehydrogenase 0.0069222
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.0069083
ANXA3 annexin A3 0.00690755
TGM2 transglutaminase 2 0.00687486
MRTFB myocardin related transcription factor B 0.00685924
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.00685664
EMP2 epithelial membrane protein 2 0.00684831
LAPTM4B lysosomal protein transmembrane 4 beta 0.00683062
IL6ST interleukin 6 signal transducer 0.00678828
POMZP3 POM121 and ZP3 fusion 0.0067356
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00671247
FGF13 fibroblast growth factor 13 0.00670618
ZBTB16 zinc finger and BTB domain containing 16 0.00661823
CDH13 cadherin 13 0.00661488
FKBP5 FK506 binding protein 5 0.00661479
PRC1 protein regulator of cytokinesis 1 0.00661474
MRPL49 mitochondrial ribosomal protein L49 0.00660506
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00660284
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.0065879
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00657892
FOLR1 folate receptor 1 (adult) 0.00654474
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00653889
CD93 CD93 molecule 0.00650118
AOC3 amine oxidase, copper containing 3 0.00650054
CPB1 carboxypeptidase B1 (tissue) 0.00649819
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00648432
LDOC1 leucine zipper, down-regulated in cancer 1 0.00647893
DYNLT1 dynein, light chain, Tctex-type 1 0.00647237
PHF20 PHD finger protein 20 0.00646114
FGFR2 fibroblast growth factor receptor 2 0.00644182
EML4 echinoderm microtubule associated protein like 4 0.00643099
ANOS1 anosmin 1 0.00642911
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00642706
TBL1X transducin (beta)-like 1X-linked 0.00642483
SDC2 syndecan 2 0.00641438
MMP2 matrix metallopeptidase 2 0.00640334
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00638194
TBC1D30 TBC1 domain family, member 30 0.00637944
RBL2 retinoblastoma-like 2 0.00637564
KIF20A kinesin family member 20A 0.00634989
NXN nucleoredoxin 0.00633393
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.00632846
SLC25A46 solute carrier family 25, member 46 0.00632269
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00631542
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.0063085
LAMA5 laminin, alpha 5 0.00629322
SLIT2 slit homolog 2 (Drosophila) 0.0062868
FKBP4 FK506 binding protein 4, 59kDa 0.00627655
STXBP2 syntaxin binding protein 2 0.00627314
EGFL6 EGF-like-domain, multiple 6 0.00627217
PDE10A phosphodiesterase 10A 0.00626857
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00625274
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00624975
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00623155
BCL6 B-cell CLL/lymphoma 6 0.00622677
NELL2 NEL-like 2 (chicken) 0.00618704
DEPDC1 DEP domain containing 1 0.00616853
REEP5 receptor accessory protein 5 0.00613431
GMCL1 germ cell-less, spermatogenesis associated 1 0.00612749
TNS1 tensin 1 0.00610752
APOB apolipoprotein B 0.00609966
TIMP1 TIMP metallopeptidase inhibitor 1 0.00608361
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00605483
LEPROTL1 leptin receptor overlapping transcript-like 1 0.00600825
TLR4 toll-like receptor 4 0.00600791
ALCAM activated leukocyte cell adhesion molecule 0.00599405
RAI2 retinoic acid induced 2 0.00599398
MPC1 mitochondrial pyruvate carrier 1 0.00598657
PLK1 polo-like kinase 1 0.00597493
CPE carboxypeptidase E 0.00596667
PRKD3 protein kinase D3 0.00594434
MARCHF1 membrane associated ring-CH-type finger 1 0.0059434
MN1 meningioma (disrupted in balanced translocation) 1 0.00594173
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00594076
ARHGAP6 Rho GTPase activating protein 6 0.00593931
SOX11 SRY (sex determining region Y)-box 11 0.005936
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00591812
APOH apolipoprotein H (beta-2-glycoprotein I) 0.00591517
TENT4A terminal nucleotidyltransferase 4A 0.00590197
TMEM204 transmembrane protein 204 0.00589607
MECP2 methyl CpG binding protein 2 0.00589341
GRB14 growth factor receptor-bound protein 14 0.00587343
RAB4A RAB4A, member RAS oncogene family 0.00585258
SLBP stem-loop binding protein 0.00584143
NKX3-1 NK3 homeobox 1 0.00583894
AUTS2 autism susceptibility candidate 2 0.00583862
TRAPPC4 trafficking protein particle complex 4 0.005837
WASF1 WAS protein family, member 1 0.00582791
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.0057966
ADCY1 adenylate cyclase 1 (brain) 0.00579181
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 0.00577333
CRIP2 cysteine-rich protein 2 0.00575181
NTAN1 N-terminal asparagine amidase 0.00574254
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0057424
CFD complement factor D (adipsin) 0.00573796
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00573654
SOCS5 suppressor of cytokine signaling 5 0.00572938
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.00572894
JADE1 jade family PHD finger 1 0.00571319
ATAD2 ATPase family, AAA domain containing 2 0.00570306
COL4A5 collagen, type IV, alpha 5 0.00569949
C2CD2 C2 calcium-dependent domain containing 2 0.00569447
RPN2 ribophorin II 0.00568873
NGRN neugrin, neurite outgrowth associated 0.00566891
TOMM34 translocase of outer mitochondrial membrane 34 0.00566795
FDPS farnesyl diphosphate synthase 0.00565763
COX7C cytochrome c oxidase subunit VIIc 0.00562516
CD302 CD302 molecule 0.00562347
ATP5MG ATP synthase membrane subunit g 0.00561839
DCP2 decapping mRNA 2 0.00561716
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00560966
WT1 Wilms tumor 1 0.00559958
CDC42 cell division cycle 42 0.00559393
NDRG3 NDRG family member 3 0.00559229
PBK PDZ binding kinase 0.00555009
CBX1 chromobox homolog 1 0.00554297
TGFBR3 transforming growth factor, beta receptor III 0.00554276
FASTKD3 FAST kinase domains 3 0.00554099
ACADL acyl-CoA dehydrogenase, long chain 0.00553769
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00553287
MSMB microseminoprotein, beta- 0.0055213
HCRT hypocretin (orexin) neuropeptide precursor 0.00551881
HMGN3 high mobility group nucleosomal binding domain 3 0.00551699
THSD7A thrombospondin, type I, domain containing 7A 0.00550508
DHCR7 7-dehydrocholesterol reductase 0.00548426
NAIP NLR family, apoptosis inhibitory protein 0.00544754
BCAP31 B-cell receptor-associated protein 31 0.00544604
MSLN mesothelin 0.00542931
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00542775
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.00541617
HOXB2 homeobox B2 0.00541193
RNF4 ring finger protein 4 0.00540883
CPB2 carboxypeptidase B2 (plasma) 0.00540717
MPZL2 myelin protein zero-like 2 0.00540376
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.00539851
NPTX1 neuronal pentraxin I 0.00539572
CCL14 chemokine (C-C motif) ligand 14 0.00538908
CLGN calmegin 0.00538496
PER3 period circadian clock 3 0.00537985
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00537251
ZNF467 zinc finger protein 467 0.00535808
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.00535548
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.00534402
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.00534023
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00531692
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.00530552
COX7B cytochrome c oxidase subunit VIIb 0.00529301
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00529105
TWSG1 twisted gastrulation BMP signaling modulator 1 0.005285
NAAA N-acylethanolamine acid amidase 0.00528376
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.00528021
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 0.00527367
ZNF512B zinc finger protein 512B 0.00526592
G6PD glucose-6-phosphate dehydrogenase 0.00525744
GANAB glucosidase, alpha; neutral AB 0.00524903
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00524645
CCL21 chemokine (C-C motif) ligand 21 0.00523529
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.0052252

decreased expression

Symbol Name Standardized Value
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.0134486
TUBB2A tubulin, beta 2A class IIa -0.0127598
OPHN1 oligophrenin 1 -0.0118303
CRYAB crystallin, alpha B -0.0113883
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.010964
PRUNE2 prune homolog 2 (Drosophila) -0.0109347
SCD5 stearoyl-CoA desaturase 5 -0.0105553
PROM1 prominin 1 -0.0104709
ATF3 activating transcription factor 3 -0.0103759
TFF3 trefoil factor 3 (intestinal) -0.0103261
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0102896
FABP7 fatty acid binding protein 7, brain -0.0102341
KLK10 kallikrein-related peptidase 10 -0.0100361
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00985708
TUBB2B tubulin, beta 2B class IIb -0.00967556
PNMA2 paraneoplastic Ma antigen 2 -0.00963983
LCN2 lipocalin 2 -0.00957712
MEN1 multiple endocrine neoplasia I -0.00948955
AOC1 amine oxidase, copper containing 1 -0.00946708
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00936911
SPRY2 sprouty homolog 2 (Drosophila) -0.00934764
POU2AF1 POU class 2 associating factor 1 -0.00931493
MYBPC1 myosin binding protein C, slow type -0.00926882
FGF1 fibroblast growth factor 1 (acidic) -0.00921521
SATB2 SATB homeobox 2 -0.00916758
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00909766
PMP2 peripheral myelin protein 2 -0.00903655
NRCAM neuronal cell adhesion molecule -0.00895109
ZMAT3 zinc finger, matrin-type 3 -0.00893629
ECM1 extracellular matrix protein 1 -0.00889607
BAMBI BMP and activin membrane-bound inhibitor -0.00884989
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00882444
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00882387
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00852475
CLCA1 chloride channel accessory 1 -0.00848026
S100A7 S100 calcium binding protein A7 -0.00847786
CRABP1 cellular retinoic acid binding protein 1 -0.00845928
KLK6 kallikrein-related peptidase 6 -0.00841711
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00837695
BHLHE41 basic helix-loop-helix family, member e41 -0.00827242
LGALS9 lectin, galactoside-binding, soluble, 9 -0.00824969
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00824134
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00820709
S100B S100 calcium binding protein B -0.00819792
ADA adenosine deaminase -0.00819162
PDZK1IP1 PDZK1 interacting protein 1 -0.00812429
ZIC1 Zic family member 1 -0.00810096
CCN2 cellular communication network factor 2 -0.00808259
FCGBP Fc fragment of IgG binding protein -0.00807466
MAP2K2 mitogen-activated protein kinase kinase 2 -0.00800635
MZB1 marginal zone B and B1 cell-specific protein -0.00800125
IFI27 interferon, alpha-inducible protein 27 -0.00795616
ACTA1 actin, alpha 1, skeletal muscle -0.00791631
DHDDS dehydrodolichyl diphosphate synthase -0.0079052
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.0079007
TTN titin -0.00786242
IQCG IQ motif containing G -0.00783808
GSTP1 glutathione S-transferase pi 1 -0.00782182
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.00780542
TCTN2 tectonic family member 2 -0.00779262
RCAN1 regulator of calcineurin 1 -0.00773584
IER5 immediate early response 5 -0.00773012
TFF1 trefoil factor 1 -0.00772385
PADI2 peptidyl arginine deiminase, type II -0.00772111
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00766806
CKM creatine kinase, muscle -0.00766145
SFRP4 secreted frizzled-related protein 4 -0.00757225
PAQR6 progestin and adipoQ receptor family member VI -0.00752324
GYPC glycophorin C (Gerbich blood group) -0.00748228
LCK LCK proto-oncogene, Src family tyrosine kinase -0.00746972
CA12 carbonic anhydrase XII -0.00744809
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00744233
S100A8 S100 calcium binding protein A8 -0.00741086
TMEM176A transmembrane protein 176A -0.0073713
GPX2 glutathione peroxidase 2 -0.00737121
RUNX1 runt-related transcription factor 1 -0.00736858
NRIP3 nuclear receptor interacting protein 3 -0.00733734
PLTP phospholipid transfer protein -0.0073125
HSPA2 heat shock 70kDa protein 2 -0.00730014
CD58 CD58 molecule -0.00725794
TNNC2 troponin C type 2 (fast) -0.00721581
GSAP gamma-secretase activating protein -0.00721375
KLF6 Kruppel-like factor 6 -0.00721275
ADM adrenomedullin -0.0072082
DPEP1 dipeptidase 1 (renal) -0.00718957
FNDC3B fibronectin type III domain containing 3B -0.00715153
KIAA0226L KIAA0226-like -0.00710706
SLN sarcolipin -0.00710448
CYBA cytochrome b-245, alpha polypeptide -0.00707026
INSM1 insulinoma-associated 1 -0.00706656
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00704807
BEX1 brain expressed, X-linked 1 -0.00702331
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00702287
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00702275
ETHE1 ethylmalonic encephalopathy 1 -0.00701092
MME membrane metallo-endopeptidase -0.00700208
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00699389
LY6D lymphocyte antigen 6 complex, locus D -0.0069485
TICAM1 toll-like receptor adaptor molecule 1 -0.00692365
TMEM176B transmembrane protein 176B -0.00689618
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00684243
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00683482
KANK1 KN motif and ankyrin repeat domains 1 -0.00683069
TUBB3 tubulin, beta 3 class III -0.00682254
EAF2 ELL associated factor 2 -0.0067999
IFIH1 interferon induced with helicase C domain 1 -0.0067977
MMP12 matrix metallopeptidase 12 -0.00679666
REG1A regenerating islet-derived 1 alpha -0.00678743
OLFML2A olfactomedin-like 2A -0.00677433
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.00677011
KRT81 keratin 81, type II -0.00674688
C1S complement component 1, s subcomponent -0.00674497
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00673061
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00669857
PLP1 proteolipid protein 1 -0.00669775
NPEPL1 aminopeptidase-like 1 -0.00668202
KIAA0753 KIAA0753 -0.00665762
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00665581
COG2 component of oligomeric golgi complex 2 -0.00664438
EPS8L3 EPS8-like 3 -0.0066083
CNTN1 contactin 1 -0.00658967
ARFIP2 ADP-ribosylation factor interacting protein 2 -0.0065864
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00658322
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00657428
YBX3 Y box binding protein 3 -0.00653939
LEFTY1 left-right determination factor 1 -0.0065362
PSAP prosaposin -0.00653408
IFI6 interferon, alpha-inducible protein 6 -0.00652869
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00652868
NT5E 5'-nucleotidase, ecto (CD73) -0.00652311
EPHB2 EPH receptor B2 -0.00649822
CLTB clathrin, light chain B -0.00648102
MARCKSL1 MARCKS-like 1 -0.00643385
ZMYM2 zinc finger, MYM-type 2 -0.00640351
TCAP titin-cap -0.00640324
BMP2 bone morphogenetic protein 2 -0.00639022
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00639
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00637214
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.00636614
KLK13 kallikrein-related peptidase 13 -0.00636509
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00635916
CLIP3 CAP-GLY domain containing linker protein 3 -0.00635527
CLIP2 CAP-GLY domain containing linker protein 2 -0.00634868
DUSP5 dual specificity phosphatase 5 -0.0063069
BIK BCL2-interacting killer (apoptosis-inducing) -0.00630226
MXRA8 matrix-remodelling associated 8 -0.00626335
LGMN legumain -0.00626314
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00625233
ISG20 interferon stimulated exonuclease gene 20kDa -0.00625197
JUNB jun B proto-oncogene -0.00624236
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00624113
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00623841
ATP10B ATPase, class V, type 10B -0.00623078
CRNN cornulin -0.00622974
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00621775
HLA-B major histocompatibility complex, class I, B -0.0062065
KLF2 Kruppel-like factor 2 -0.00620022
RHCG Rh family, C glycoprotein -0.00619793
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00617631
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00617451
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.0061702
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -0.00615751
ITGA7 integrin, alpha 7 -0.00615468
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00610867
USP18 ubiquitin specific peptidase 18 -0.00610211
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00608615
MEF2C myocyte enhancer factor 2C -0.00608059
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00603812
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00603717
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -0.00601021
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00600984
KLHL41 kelch-like family member 41 -0.00600634
SMPX small muscle protein, X-linked -0.00600197
KLK11 kallikrein-related peptidase 11 -0.00598338
ABHD4 abhydrolase domain containing 4 -0.0059709
MAP1A microtubule-associated protein 1A -0.0059695
PTPRE protein tyrosine phosphatase, receptor type, E -0.00596534
LOXL1 lysyl oxidase-like 1 -0.00595269
CD79A CD79a molecule, immunoglobulin-associated alpha -0.0059246
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -0.00592197
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00591494
KRT16 keratin 16, type I -0.00590174
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00589921
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00588147
CLCA4 chloride channel accessory 4 -0.00588065
RRBP1 ribosome binding protein 1 -0.00587249
CCL20 chemokine (C-C motif) ligand 20 -0.00587112
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -0.00585566
PUF60 poly-U binding splicing factor 60KDa -0.00584409
STEAP3 STEAP family member 3, metalloreductase -0.00583012
HSPB1 heat shock 27kDa protein 1 -0.00582426
NR1H2 nuclear receptor subfamily 1, group H, member 2 -0.00582042
OPTN optineurin -0.00581509
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -0.00580611
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00580171
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00578812
PYCARD PYD and CARD domain containing -0.00575678
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00575445
LAT2 linker for activation of T cells family, member 2 -0.00574831
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00572843
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00571133
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0057028
KLK12 kallikrein-related peptidase 12 -0.00567224
DAPK3 death-associated protein kinase 3 -0.00567204
AK1 adenylate kinase 1 -0.00566437
FAIM2 Fas apoptotic inhibitory molecule 2 -0.0056573
MX2 MX dynamin-like GTPase 2 -0.00564848
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0056434
TGFA transforming growth factor, alpha -0.00563144
PTHLH parathyroid hormone-like hormone -0.00560682
CDX1 caudal type homeobox 1 -0.005606
AZIN1 antizyme inhibitor 1 -0.00560139
NOP53 NOP53 ribosome biogenesis factor -0.00559463
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00558131
SOX10 SRY (sex determining region Y)-box 10 -0.00558053
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.0055777
LIPG lipase, endothelial -0.00557565
GFAP glial fibrillary acidic protein -0.00557357
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -0.00555226
BIN1 bridging integrator 1 -0.00554104
GMDS GDP-mannose 4,6-dehydratase -0.00553366
GPM6B glycoprotein M6B -0.00552917
IL32 interleukin 32 -0.0055283
IL2RG interleukin 2 receptor, gamma -0.00552016
GAS7 growth arrest-specific 7 -0.00551779
DMPK dystrophia myotonica-protein kinase -0.00551244
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00549439
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.0054939
TM9SF3 transmembrane 9 superfamily member 3 -0.00549314
NFE2L3 nuclear factor, erythroid 2-like 3 -0.00548733
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00548634
BCL3 B-cell CLL/lymphoma 3 -0.00547796
VGF VGF nerve growth factor inducible -0.00547479
AKIRIN1 akirin 1 -0.00547028
WEE1 WEE1 G2 checkpoint kinase -0.00546984
HBEGF heparin-binding EGF-like growth factor -0.00545109
MREG melanoregulin -0.00542453
PTCH1 patched 1 -0.00541479
FBN2 fibrillin 2 -0.00541107
DNTT DNA nucleotidylexotransferase -0.00540921
DEFB4A defensin, beta 4A -0.0053986
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00539459
TNNC1 troponin C type 1 (slow) -0.00538735
DOK5 docking protein 5 -0.0053827
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -0.00537474
TTYH1 tweety family member 1 -0.00537072
TTC38 tetratricopeptide repeat domain 38 -0.00536349
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00535474
HSPB6 heat shock protein, alpha-crystallin-related, B6 -0.00534833