| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | plasminogen activator, tissue|This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5327) |
| External Link | https://ncbi.nlm.nih.gov/gene/5327 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PLAT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0193349 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0167432 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0157265 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0147163 |
| RPA3 | replication protein A3, 14kDa | 0.0143567 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0121553 |
| FABP1 | fatty acid binding protein 1, liver | 0.0112556 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.010634 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0106135 |
| GNAS | GNAS complex locus | 0.0102682 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00995832 |
| SCG5 | secretogranin V | 0.00988569 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0098632 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00951308 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0094954 |
| HOXC6 | homeobox C6 | 0.00948958 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00935683 |
| MT1F | metallothionein 1F | 0.00929721 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.00911689 |
| COQ8A | coenzyme Q8A | 0.00908752 |
| H2AFV | H2A histone family, member V | 0.00896456 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.00874298 |
| STK10 | serine/threonine kinase 10 | 0.00873617 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00856552 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00846951 |
| LOX | lysyl oxidase | 0.00841109 |
| NPR3 | natriuretic peptide receptor 3 | 0.00841102 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00837925 |
| EAPP | E2F-associated phosphoprotein | 0.00834141 |
| WT1 | Wilms tumor 1 | 0.00833251 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00819105 |
| NNMT | nicotinamide N-methyltransferase | 0.00818135 |
| CYTL1 | cytokine-like 1 | 0.00801675 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 0.00800292 |
| ANGPT1 | angiopoietin 1 | 0.00795526 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0079271 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.0079161 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.007885 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00782676 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.00782565 |
| TMEM38B | transmembrane protein 38B | 0.00782434 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00776164 |
| CLCA1 | chloride channel accessory 1 | 0.00775289 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00757567 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.00757136 |
| EBAG9 | estrogen receptor binding site associated, antigen, 9 | 0.00755321 |
| FAM216A | family with sequence similarity 216, member A | 0.0074472 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00743732 |
| TXNIP | thioredoxin interacting protein | 0.00735277 |
| FRZB | frizzled-related protein | 0.00728912 |
| ACYP2 | acylphosphatase 2, muscle type | 0.00725174 |
| MT1E | metallothionein 1E | 0.00724008 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00720634 |
| FOXC1 | forkhead box C1 | 0.00719914 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00718438 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00717263 |
| QDPR | quinoid dihydropteridine reductase | 0.00716986 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00712578 |
| PITX3 | paired-like homeodomain 3 | 0.00709988 |
| PRKD3 | protein kinase D3 | 0.00709671 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00707962 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00706869 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00702922 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00700942 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.0069955 |
| COMMD8 | COMM domain containing 8 | 0.00699188 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00696451 |
| PURA | purine-rich element binding protein A | 0.00695504 |
| SEPTIN7 | septin 7 | 0.00691141 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 | 0.00689823 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.006898 |
| CCNE2 | cyclin E2 | 0.00686582 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00685717 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00683848 |
| MEIS1 | Meis homeobox 1 | 0.00683146 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 0.00682078 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00679397 |
| CDC7 | cell division cycle 7 | 0.00676607 |
| FNDC3A | fibronectin type III domain containing 3A | 0.00675713 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | 0.00674492 |
| MIS12 | MIS12 kinetochore complex component | 0.00672396 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00667658 |
| RMI1 | RecQ mediated genome instability 1 | 0.00663978 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00663832 |
| ZG16 | zymogen granule protein 16 | 0.00663465 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00662706 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00662647 |
| HLTF | helicase-like transcription factor | 0.00661465 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00660308 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | 0.00657673 |
| GNG5 | guanine nucleotide binding protein (G protein), gamma 5 | 0.00651749 |
| SDC2 | syndecan 2 | 0.00650081 |
| IFI44 | interferon-induced protein 44 | 0.00649787 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.0064754 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00645499 |
| TMEM14B | transmembrane protein 14B | 0.00642631 |
| OIP5 | Opa interacting protein 5 | 0.00642598 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.0064187 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00641085 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00641043 |
| ABHD10 | abhydrolase domain containing 10 | 0.00640689 |
| ITK | IL2-inducible T-cell kinase | 0.00640438 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00638238 |
| MAT2B | methionine adenosyltransferase II, beta | 0.0063811 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | 0.00635153 |
| C11ORF21 | chromosome 11 open reading frame 21 | 0.0063355 |
| TM2D3 | TM2 domain containing 3 | 0.00633485 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00633475 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00633019 |
| TOB1 | transducer of ERBB2, 1 | 0.00632392 |
| PHTF2 | putative homeodomain transcription factor 2 | 0.0063162 |
| CHEK2 | checkpoint kinase 2 | 0.00631394 |
| INSIG1 | insulin induced gene 1 | 0.00631125 |
| FPGT | fucose-1-phosphate guanylyltransferase | 0.00630543 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00626832 |
| PROM1 | prominin 1 | 0.00626427 |
| PDZK1 | PDZ domain containing 1 | 0.00625523 |
| EVI2A | ecotropic viral integration site 2A | 0.00624587 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00622879 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00619275 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit | 0.00619175 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.00617352 |
| TEX30 | testis expressed 30 | 0.00615667 |
| L1CAM | L1 cell adhesion molecule | 0.00615242 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00614009 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.00611834 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00610669 |
| LIPT1 | lipoyltransferase 1 | 0.00609351 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00607747 |
| RPL26L1 | ribosomal protein L26-like 1 | 0.00606633 |
| MICB | MHC class I polypeptide-related sequence B | 0.0060641 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00602899 |
| HAMP | hepcidin antimicrobial peptide | 0.00598286 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00596419 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00593703 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00592213 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.00592173 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 0.00587299 |
| FKTN | fukutin | 0.00584935 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.0058345 |
| PDGFC | platelet derived growth factor C | 0.00582667 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00580849 |
| MLH1 | mutL homolog 1 | 0.00580803 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00579062 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.00578273 |
| FBXO3 | F-box protein 3 | 0.00578157 |
| FAM13B | family with sequence similarity 13, member B | 0.00577179 |
| MT1G | metallothionein 1G | 0.00575786 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0057546 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 | 0.00574742 |
| DUT | deoxyuridine triphosphatase | 0.00574627 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00574556 |
| MAPKAPK5-AS1 | MAPKAPK5 antisense RNA 1 | 0.00574439 |
| PER3 | period circadian clock 3 | 0.00572765 |
| CDCA4 | cell division cycle associated 4 | 0.00571741 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 0.00570437 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00570112 |
| GCG | glucagon | 0.00569521 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00569489 |
| CHGB | chromogranin B | 0.00567388 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00566688 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00564006 |
| SORD | sorbitol dehydrogenase | 0.00562338 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00561946 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.0056181 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00560845 |
| MT1H | metallothionein 1H | 0.00560175 |
| OSER1 | oxidative stress responsive serine-rich 1 | 0.00558228 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00558006 |
| RAB14 | RAB14, member RAS oncogene family | 0.00557458 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.00557211 |
| CLEC2B | C-type lectin domain family 2, member B | 0.0055611 |
| CARTPT | CART prepropeptide | 0.00555805 |
| SLC16A6 | solute carrier family 16, member 6 | 0.00555086 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00554948 |
| CCNB2 | cyclin B2 | 0.00554082 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00553003 |
| ZNF14 | zinc finger protein 14 | 0.0055096 |
| PKNOX1 | PBX/knotted 1 homeobox 1 | 0.00550908 |
| UNG | uracil-DNA glycosylase | 0.00550577 |
| AURKA | aurora kinase A | 0.00549541 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00548784 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0054867 |
| TPRKB | TP53RK binding protein | 0.00548631 |
| C5ORF30 | chromosome 5 open reading frame 30 | 0.00547999 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 0.00547676 |
| PCYOX1L | prenylcysteine oxidase 1 like | 0.00547322 |
| IL15 | interleukin 15 | 0.00546674 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00546609 |
| SLC44A4 | solute carrier family 44, member 4 | 0.0054608 |
| KIAA0125 | KIAA0125 | 0.00543388 |
| CHMP6 | charged multivesicular body protein 6 | 0.00543195 |
| MTERF3 | mitochondrial transcription termination factor 3 | 0.00542666 |
| FAM46C | family with sequence similarity 46, member C | 0.00541732 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00540627 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0054034 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | 0.00540317 |
| RNF139 | ring finger protein 139 | 0.00539822 |
| LYRM1 | LYR motif containing 1 | 0.00539587 |
| CCNA2 | cyclin A2 | 0.00539422 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00538875 |
| PPAT | phosphoribosyl pyrophosphate amidotransferase | 0.00538064 |
| MPO | myeloperoxidase | 0.00537049 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00536455 |
| CETN3 | centrin, EF-hand protein, 3 | 0.00536408 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00536232 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.0053574 |
| CMC2 | C-x(9)-C motif containing 2 | 0.00535255 |
| MPHOSPH9 | M-phase phosphoprotein 9 | 0.00534944 |
| IRX5 | iroquois homeobox 5 | 0.00534773 |
| B2M | beta-2-microglobulin | 0.00534612 |
| MRPL36 | mitochondrial ribosomal protein L36 | 0.00534455 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00533378 |
| SNAI2 | snail family zinc finger 2 | 0.00532449 |
| TPH1 | tryptophan hydroxylase 1 | 0.00531798 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | 0.00530992 |
| BCAS2 | breast carcinoma amplified sequence 2 | 0.00530652 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 | 0.00530178 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00529612 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.00526985 |
| CEL | carboxyl ester lipase | 0.00526951 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00526306 |
| SHLD2 | shieldin complex subunit 2 | 0.00525776 |
| HSF2 | heat shock transcription factor 2 | 0.0052526 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00524628 |
| SRGN | serglycin | 0.00523976 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00523736 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00523009 |
| ADK | adenosine kinase | 0.00522321 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00521805 |
| CLK4 | CDC-like kinase 4 | 0.0052071 |
| CEP70 | centrosomal protein 70kDa | 0.00519338 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00519112 |
| RWDD2B | RWD domain containing 2B | 0.00518773 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.00518389 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.00517745 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 | 0.00517526 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00517448 |
| SYCP2 | synaptonemal complex protein 2 | 0.00517014 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00516875 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00516412 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00515999 |
| POFUT1 | protein O-fucosyltransferase 1 | 0.00515651 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00513914 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.00513773 |
| KANSL2 | KAT8 regulatory NSL complex subunit 2 | 0.00513523 |
| CKAP2 | cytoskeleton associated protein 2 | 0.00513209 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00512641 |
| FST | follistatin | 0.00511967 |
| CD48 | CD48 molecule | 0.0051182 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | -0.0157994 |
| MGP | matrix Gla protein | -0.0132003 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0130773 |
| S100A9 | S100 calcium binding protein A9 | -0.0129275 |
| IL1RN | interleukin 1 receptor antagonist | -0.0127497 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0120372 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.0117554 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0115882 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0111489 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0111274 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0108316 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0107112 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0106352 |
| CTSH | cathepsin H | -0.0105779 |
| KIAA0930 | KIAA0930 | -0.0105449 |
| OPHN1 | oligophrenin 1 | -0.0104473 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0104228 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.010406 |
| S100A11 | S100 calcium binding protein A11 | -0.0103938 |
| AUTS2 | autism susceptibility candidate 2 | -0.0103249 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0103085 |
| PCNA | proliferating cell nuclear antigen | -0.010163 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0101504 |
| TYMP | thymidine phosphorylase | -0.0100866 |
| RBM47 | RNA binding motif protein 47 | -0.00965954 |
| KLK11 | kallikrein-related peptidase 11 | -0.00962153 |
| PLK2 | polo-like kinase 2 | -0.00954358 |
| TMC5 | transmembrane channel-like 5 | -0.00938069 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00934822 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00931079 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00926487 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00926111 |
| SPRR3 | small proline-rich protein 3 | -0.0092358 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.0092225 |
| KRT13 | keratin 13, type I | -0.00919308 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00912459 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00910278 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00910161 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00907634 |
| EZR | ezrin | -0.00904317 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00902229 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -0.00900907 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00899898 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00892968 |
| GPX1 | glutathione peroxidase 1 | -0.00891389 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0088971 |
| COL5A2 | collagen, type V, alpha 2 | -0.00883089 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.0088272 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00880338 |
| MVP | major vault protein | -0.0087904 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00874746 |
| PLS3 | plastin 3 | -0.00865352 |
| CHMP4A | charged multivesicular body protein 4A | -0.0086449 |
| CD9 | CD9 molecule | -0.00863593 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00860519 |
| TSPO | translocator protein (18kDa) | -0.00858224 |
| MGLL | monoglyceride lipase | -0.00857294 |
| MMP12 | matrix metallopeptidase 12 | -0.00855262 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.00853827 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00853428 |
| CES1 | carboxylesterase 1 | -0.00850662 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00847654 |
| CAV2 | caveolin 2 | -0.00847336 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00844799 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00842875 |
| MME | membrane metallo-endopeptidase | -0.00841195 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00832887 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00832042 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00831495 |
| TSPAN8 | tetraspanin 8 | -0.00830471 |
| FMOD | fibromodulin | -0.00829052 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00828818 |
| KLK10 | kallikrein-related peptidase 10 | -0.00828778 |
| PLCB4 | phospholipase C, beta 4 | -0.00826044 |
| PLXNB2 | plexin B2 | -0.00823659 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00820425 |
| TPD52L1 | tumor protein D52-like 1 | -0.00817165 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | -0.00815381 |
| TPST2 | tyrosylprotein sulfotransferase 2 | -0.00809963 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00807488 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0080468 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00803367 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00802059 |
| AGR2 | anterior gradient 2 | -0.00798168 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.00797107 |
| MX1 | MX dynamin-like GTPase 1 | -0.00791138 |
| MYOF | myoferlin | -0.00788896 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00787601 |
| GAS7 | growth arrest-specific 7 | -0.00787405 |
| FBLN1 | fibulin 1 | -0.00785566 |
| SCEL | sciellin | -0.00783996 |
| COBL | cordon-bleu WH2 repeat protein | -0.00783528 |
| KRT6A | keratin 6A, type II | -0.00781628 |
| BMP2 | bone morphogenetic protein 2 | -0.00781044 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00776647 |
| MEF2C | myocyte enhancer factor 2C | -0.0077633 |
| TRIB2 | tribbles pseudokinase 2 | -0.0077599 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.0077491 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00773814 |
| DUSP4 | dual specificity phosphatase 4 | -0.00765135 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00764928 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.00761662 |
| YBX3 | Y box binding protein 3 | -0.00760528 |
| ENAH | enabled homolog (Drosophila) | -0.00759447 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00757415 |
| KRT7 | keratin 7, type II | -0.0075739 |
| CYRIA | CYFIP related Rac1 interactor A | -0.0075699 |
| GPX2 | glutathione peroxidase 2 | -0.00754526 |
| ZNF589 | zinc finger protein 589 | -0.00750615 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00750436 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00749428 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00748756 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00746005 |
| TRIM22 | tripartite motif containing 22 | -0.007459 |
| RND3 | Rho family GTPase 3 | -0.00741407 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00739916 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00739225 |
| SPRR1B | small proline-rich protein 1B | -0.00738753 |
| PLD3 | phospholipase D family, member 3 | -0.00738148 |
| NID1 | nidogen 1 | -0.00737342 |
| RNF19B | ring finger protein 19B | -0.00735573 |
| COG7 | component of oligomeric golgi complex 7 | -0.0073078 |
| COCH | cochlin | -0.00730723 |
| MXRA5 | matrix-remodelling associated 5 | -0.00726744 |
| KRT18 | keratin 18, type I | -0.00721889 |
| NLRP2 | NLR family, pyrin domain containing 2 | -0.00721275 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0072019 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.00718999 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | -0.00716326 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00715086 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00714297 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0071391 |
| BEX1 | brain expressed, X-linked 1 | -0.00710866 |
| SIRPA | signal-regulatory protein alpha | -0.00709822 |
| BTG2 | BTG family, member 2 | -0.00708661 |
| GRN | granulin | -0.00702778 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00702273 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00700861 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00700157 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00697707 |
| PSAP | prosaposin | -0.00695389 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | -0.00694365 |
| FGG | fibrinogen gamma chain | -0.00691117 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00690298 |
| TMEM176B | transmembrane protein 176B | -0.00689524 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00688438 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00688009 |
| EHD3 | EH-domain containing 3 | -0.00687544 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00684163 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00680305 |
| GPI | glucose-6-phosphate isomerase | -0.00679591 |
| SAMM50 | SAMM50 sorting and assembly machinery component | -0.00678396 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00677509 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -0.00675892 |
| TP63 | tumor protein p63 | -0.00675502 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00674055 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00673995 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00673558 |
| LAD1 | ladinin 1 | -0.00670679 |
| VLDLR | very low density lipoprotein receptor | -0.00669319 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00668529 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00668175 |
| NOP56 | NOP56 ribonucleoprotein | -0.0066787 |
| VWF | von Willebrand factor | -0.00665532 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00665051 |
| HMOX1 | heme oxygenase 1 | -0.00663229 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00660032 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00656692 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00653574 |
| CAPNS1 | calpain, small subunit 1 | -0.00650674 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00649407 |
| TMEM35 | transmembrane protein 35 | -0.00649394 |
| PRAME | preferentially expressed antigen in melanoma | -0.00649008 |
| VCL | vinculin | -0.00648819 |
| PLA1A | phospholipase A1 member A | -0.00647495 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00646769 |
| STX3 | syntaxin 3 | -0.00646644 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00646413 |
| BCR | breakpoint cluster region | -0.00643225 |
| ANXA3 | annexin A3 | -0.0064233 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00641352 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.00640555 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00639732 |
| CD14 | CD14 molecule | -0.00639688 |
| IRF6 | interferon regulatory factor 6 | -0.00637298 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00636879 |
| ARG2 | arginase 2 | -0.00634823 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | -0.00634362 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00632886 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00630759 |
| PLPP2 | phospholipid phosphatase 2 | -0.00628654 |
| THBS2 | thrombospondin 2 | -0.00628423 |
| CD81 | CD81 molecule | -0.00628214 |
| GPR137B | G protein-coupled receptor 137B | -0.00627664 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00624409 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00624266 |
| IL32 | interleukin 32 | -0.00623911 |
| DMAC2 | distal membrane arm assembly component 2 | -0.00622826 |
| TCF4 | transcription factor 4 | -0.0062257 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00621456 |
| GSDME | gasdermin E | -0.0062136 |
| PRNP | prion protein | -0.0062112 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00621066 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00619315 |
| ATF3 | activating transcription factor 3 | -0.00618975 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00618053 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | -0.00617201 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00616873 |
| FRMD4B | FERM domain containing 4B | -0.00616694 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.00616233 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00616153 |
| TRIM29 | tripartite motif containing 29 | -0.00615043 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.00614308 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00614109 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00613293 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00613067 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00612354 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.0060992 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00609053 |
| RAB38 | RAB38, member RAS oncogene family | -0.00608975 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00608486 |
| PTHLH | parathyroid hormone-like hormone | -0.00608079 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00607757 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00606844 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.00606677 |
| GPX4 | glutathione peroxidase 4 | -0.00605391 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.00604409 |
| KRT15 | keratin 15, type I | -0.00603424 |
| COLEC12 | collectin sub-family member 12 | -0.00603373 |
| EMP1 | epithelial membrane protein 1 | -0.00602612 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0060208 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0060176 |
| USP6NL | USP6 N-terminal like | -0.00599816 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00598257 |
| TGM2 | transglutaminase 2 | -0.00596646 |
| CPM | carboxypeptidase M | -0.00596518 |
| PRSS8 | protease, serine, 8 | -0.00595151 |
| KRT23 | keratin 23, type I | -0.00593875 |
| FBN2 | fibrillin 2 | -0.00593576 |
| CLDN4 | claudin 4 | -0.00591298 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00591103 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | -0.00591016 |
| EPS8L2 | EPS8-like 2 | -0.00590926 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | -0.00590848 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00590808 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | -0.0059074 |
| ASRGL1 | asparaginase like 1 | -0.005902 |
| PDE8B | phosphodiesterase 8B | -0.00589097 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00587892 |
