| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | plasminogen activator, urokinase|This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 5328) |
| External Link | https://ncbi.nlm.nih.gov/gene/5328 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the PLAU gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0142009 |
| GNAS | GNAS complex locus | 0.0139506 |
| XPO7 | exportin 7 | 0.0129448 |
| MECOM | MDS1 and EVI1 complex locus | 0.012473 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0114992 |
| MEF2C | myocyte enhancer factor 2C | 0.0114687 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0108148 |
| MX1 | MX dynamin-like GTPase 1 | 0.0108037 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0106455 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.010624 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0104247 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0101762 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.0100796 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.01004 |
| CANX | calnexin | 0.00971431 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00971004 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00954747 |
| CA2 | carbonic anhydrase II | 0.009516 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00946524 |
| SPRR1B | small proline-rich protein 1B | 0.00932213 |
| KLK10 | kallikrein-related peptidase 10 | 0.00931828 |
| GOLM1 | golgi membrane protein 1 | 0.00929408 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.0092003 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00909104 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00904724 |
| DEFB1 | defensin, beta 1 | 0.00904176 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00900921 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00891288 |
| GTF2I | general transcription factor IIi | 0.00885577 |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.00885372 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.00884818 |
| ARG1 | arginase 1 | 0.00883409 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00883255 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0088273 |
| PRDX2 | peroxiredoxin 2 | 0.00878037 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00876253 |
| CNTN1 | contactin 1 | 0.00873359 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0087188 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00870576 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00868109 |
| PRR7 | proline rich 7 (synaptic) | 0.00851744 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00849624 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00843075 |
| TNNC1 | troponin C type 1 (slow) | 0.0083914 |
| IFI44L | interferon-induced protein 44-like | 0.00832519 |
| GLTP | glycolipid transfer protein | 0.00815142 |
| YIPF5 | Yip1 domain family, member 5 | 0.00813716 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00810137 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00807088 |
| S100A9 | S100 calcium binding protein A9 | 0.00805442 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00803485 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.00803449 |
| KLK11 | kallikrein-related peptidase 11 | 0.00801253 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00792216 |
| MSLN | mesothelin | 0.00790034 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.0078988 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.00788734 |
| CLEC11A | C-type lectin domain family 11, member A | 0.0078628 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00784326 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00781995 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.00780747 |
| PXDN | peroxidasin | 0.0077714 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00775093 |
| S100A8 | S100 calcium binding protein A8 | 0.00774525 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00771201 |
| ADORA2B | adenosine A2b receptor | 0.00771069 |
| MCL1 | myeloid cell leukemia 1 | 0.0077101 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00768192 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00767664 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00766198 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00765258 |
| ENDOD1 | endonuclease domain containing 1 | 0.00765249 |
| TMEM45A | transmembrane protein 45A | 0.0076208 |
| ACTB | actin, beta | 0.00758625 |
| SMAD5 | SMAD family member 5 | 0.0075641 |
| EXOC5 | exocyst complex component 5 | 0.00755926 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.00748667 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00746169 |
| ANXA6 | annexin A6 | 0.00743186 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00741999 |
| HAL | histidine ammonia-lyase | 0.00740714 |
| AHNAK | AHNAK nucleoprotein | 0.00739839 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.00732665 |
| COL3A1 | collagen, type III, alpha 1 | 0.00729264 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.0072854 |
| MPZL2 | myelin protein zero-like 2 | 0.00727431 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00721758 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | 0.00719493 |
| MSX1 | msh homeobox 1 | 0.00718262 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 | 0.00714972 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.00713463 |
| DUSP4 | dual specificity phosphatase 4 | 0.00707967 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00707711 |
| ADAMTSL3 | ADAMTS-like 3 | 0.00707451 |
| PRNP | prion protein | 0.00706684 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00702739 |
| RELN | reelin | 0.00699311 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.00696129 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.00690418 |
| SPIN1 | spindlin 1 | 0.00689852 |
| PDAP1 | PDGFA associated protein 1 | 0.00689452 |
| OPHN1 | oligophrenin 1 | 0.00687833 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00681844 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00679263 |
| SFTPC | surfactant protein C | 0.00676957 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00675103 |
| ARHGAP44 | Rho GTPase activating protein 44 | 0.00671785 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.00671586 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00671191 |
| MID1IP1 | MID1 interacting protein 1 | 0.00670722 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00670444 |
| CD14 | CD14 molecule | 0.00666509 |
| DCTN4 | dynactin 4 (p62) | 0.0066585 |
| CTSG | cathepsin G | 0.00665799 |
| ZNF106 | zinc finger protein 106 | 0.00665498 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00664617 |
| FN1 | fibronectin 1 | 0.00663967 |
| CES1 | carboxylesterase 1 | 0.00662133 |
| ESR1 | estrogen receptor 1 | 0.00661601 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00661301 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00660668 |
| GAS7 | growth arrest-specific 7 | 0.00655087 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0065328 |
| MEIS1 | Meis homeobox 1 | 0.00650856 |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.00648065 |
| ISL1 | ISL LIM homeobox 1 | 0.00647677 |
| PDZD2 | PDZ domain containing 2 | 0.00642341 |
| UBXN7 | UBX domain protein 7 | 0.0064193 |
| TTN | titin | 0.00641012 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0063815 |
| S100A2 | S100 calcium binding protein A2 | 0.00636913 |
| FAM3C | family with sequence similarity 3, member C | 0.00636754 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00636342 |
| PPID | peptidylprolyl isomerase D | 0.0063566 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00635202 |
| C4BPA | complement component 4 binding protein, alpha | 0.00635147 |
| TYRP1 | tyrosinase-related protein 1 | 0.00629692 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00625709 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00625266 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.00624509 |
| BCHE | butyrylcholinesterase | 0.00622874 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.00622297 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00622183 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 0.00621626 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.00621445 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00616622 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.00615235 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.00614685 |
| LMAN1 | lectin, mannose-binding, 1 | 0.00614139 |
| MMP2 | matrix metallopeptidase 2 | 0.00613896 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00611523 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.0060958 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00606819 |
| STK24 | serine/threonine kinase 24 | 0.00606073 |
| LMNB1 | lamin B1 | 0.00605574 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00605325 |
| EXPH5 | exophilin 5 | 0.00605219 |
| GANAB | glucosidase, alpha; neutral AB | 0.00605114 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.00603564 |
| MPO | myeloperoxidase | 0.0060201 |
| MCC | mutated in colorectal cancers | 0.00601017 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00598525 |
| ITGA6 | integrin, alpha 6 | 0.00596415 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.0059639 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00596068 |
| CCL14 | chemokine (C-C motif) ligand 14 | 0.00591388 |
| ETV1 | ets variant 1 | 0.00589915 |
| LIF | leukemia inhibitory factor | 0.00589814 |
| NELL1 | NEL-like 1 (chicken) | 0.00588971 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00588037 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.00587554 |
| SLC35E1 | solute carrier family 35, member E1 | 0.005872 |
| PLAT | plasminogen activator, tissue | 0.00584453 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00582712 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.00581725 |
| ACLY | ATP citrate lyase | 0.00580928 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00580605 |
| TPBG | trophoblast glycoprotein | 0.00580206 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.00579448 |
| GPX3 | glutathione peroxidase 3 | 0.00577342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.00576713 |
| AMOTL2 | angiomotin like 2 | 0.00573729 |
| H1-0 | H1.0 linker histone | 0.00573429 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00571163 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.00571102 |
| F12 | coagulation factor XII (Hageman factor) | 0.00571068 |
| TCAF1 | TRPM8 channel-associated factor 1 | 0.00570631 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00570534 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.00569166 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00569072 |
| C3 | complement component 3 | 0.00568583 |
| ZNF750 | zinc finger protein 750 | 0.00568288 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00568177 |
| CNN3 | calponin 3, acidic | 0.00567633 |
| KLK7 | kallikrein-related peptidase 7 | 0.00567624 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00567595 |
| CD9 | CD9 molecule | 0.00565788 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.00564211 |
| YBX3 | Y box binding protein 3 | 0.00563736 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | 0.00561864 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00560959 |
| ABHD17B | abhydrolase domain containing 17B | 0.00560619 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0056023 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00559723 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00559147 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.00558552 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.005577 |
| RDX | radixin | 0.00557162 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00556821 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00556753 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.00555682 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.00555025 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00553469 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 0.00553068 |
| RBM48 | RNA binding motif protein 48 | 0.00553034 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00552826 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00552797 |
| CLDND1 | claudin domain containing 1 | 0.00552002 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00551444 |
| PLTP | phospholipid transfer protein | 0.00549742 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.00547637 |
| MYO1B | myosin IB | 0.00547603 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00546187 |
| KRT1 | keratin 1, type II | 0.00545193 |
| FOXF1 | forkhead box F1 | 0.00544855 |
| FGF9 | fibroblast growth factor 9 | 0.00544488 |
| CS | citrate synthase | 0.00544367 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.0054238 |
| TGM2 | transglutaminase 2 | 0.00540921 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0054026 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0053988 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00539828 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00539327 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00536486 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | 0.00535693 |
| CST6 | cystatin E/M | 0.00534985 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00533842 |
| CFI | complement factor I | 0.00530875 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.00530749 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 0.00529475 |
| DBT | dihydrolipoamide branched chain transacylase E2 | 0.00529061 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00525395 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.00524983 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00523808 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00523394 |
| GAB1 | GRB2-associated binding protein 1 | 0.00523378 |
| HYOU1 | hypoxia up-regulated 1 | 0.00522406 |
| LTA4H | leukotriene A4 hydrolase | 0.00522055 |
| NRN1 | neuritin 1 | 0.0052203 |
| GAB2 | GRB2-associated binding protein 2 | 0.005215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0188784 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0145221 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0138789 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.0135854 |
| NTS | neurotensin | -0.0135776 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0131102 |
| MAGEA3 | melanoma antigen family A3 | -0.0121479 |
| TFF1 | trefoil factor 1 | -0.012106 |
| S100P | S100 calcium binding protein P | -0.0113682 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.011255 |
| KRT7 | keratin 7, type II | -0.0112495 |
| NID2 | nidogen 2 (osteonidogen) | -0.0111462 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0110978 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0109076 |
| CD38 | CD38 molecule | -0.0108843 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.0104506 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0103806 |
| STAT4 | signal transducer and activator of transcription 4 | -0.0102658 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.0102542 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.0101071 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00992335 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00990603 |
| MAP7 | microtubule-associated protein 7 | -0.00981883 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00975146 |
| ADIRF | adipogenesis regulatory factor | -0.00974417 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00971392 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00956453 |
| GALC | galactosylceramidase | -0.00944708 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00935732 |
| HEPH | hephaestin | -0.00933118 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00916193 |
| KYNU | kynureninase | -0.00913574 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.0086626 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.0085892 |
| CHMP6 | charged multivesicular body protein 6 | -0.00857322 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00856342 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0084866 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00842852 |
| XYLT1 | xylosyltransferase I | -0.00842198 |
| IL7R | interleukin 7 receptor | -0.00840843 |
| AGR2 | anterior gradient 2 | -0.00838917 |
| PXDC1 | PX domain containing 1 | -0.00833608 |
| APOD | apolipoprotein D | -0.00826655 |
| TOX3 | TOX high mobility group box family member 3 | -0.00812129 |
| COMP | cartilage oligomeric matrix protein | -0.00810876 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00807559 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00806044 |
| MMP12 | matrix metallopeptidase 12 | -0.00805989 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00804228 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00800894 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00798243 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00793892 |
| PLIN2 | perilipin 2 | -0.0079281 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00790463 |
| CRYM | crystallin, mu | -0.00786443 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0078034 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00779438 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00778581 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | -0.00769993 |
| OFD1 | oral-facial-digital syndrome 1 | -0.00763134 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00757476 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00756969 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00754729 |
| MMP7 | matrix metallopeptidase 7 | -0.00750351 |
| IL2RG | interleukin 2 receptor, gamma | -0.00749804 |
| CLU | clusterin | -0.00749396 |
| PIR | pirin (iron-binding nuclear protein) | -0.00742509 |
| TARP | TCR gamma alternate reading frame protein | -0.00740885 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00737084 |
| NEBL | nebulette | -0.00733668 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | -0.00730794 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00730307 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00729928 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.00726071 |
| REG1A | regenerating islet-derived 1 alpha | -0.00725458 |
| HOXC6 | homeobox C6 | -0.00721667 |
| CD8A | CD8a molecule | -0.00717331 |
| SRGN | serglycin | -0.00714605 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00712322 |
| ITGAV | integrin, alpha V | -0.0071214 |
| PF4 | platelet factor 4 | -0.00710425 |
| GPX2 | glutathione peroxidase 2 | -0.00706391 |
| NNMT | nicotinamide N-methyltransferase | -0.00701806 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | -0.00698538 |
| EFHD2 | EF-hand domain family, member D2 | -0.00695367 |
| PIP | prolactin-induced protein | -0.00694896 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.00689122 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.00688178 |
| CHMP4A | charged multivesicular body protein 4A | -0.00684476 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00679434 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00677053 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00672501 |
| BUB3 | BUB3 mitotic checkpoint protein | -0.00671752 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00670519 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0066731 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.006668 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00665313 |
| NEFH | neurofilament, heavy polypeptide | -0.00665208 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00664204 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | -0.0066227 |
| XIC | X chromosome inactivation center | -0.00661348 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00660531 |
| ETNK1 | ethanolamine kinase 1 | -0.00659591 |
| RAB21 | RAB21, member RAS oncogene family | -0.00653175 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00651479 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00646892 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -0.00644847 |
| SLAMF7 | SLAM family member 7 | -0.00641095 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00639537 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00636866 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.00633887 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00633279 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00633245 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00632265 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00628739 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.00628671 |
| TSPAN4 | tetraspanin 4 | -0.00628543 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00627754 |
| MFAP5 | microfibrillar associated protein 5 | -0.00627348 |
| QKI | QKI, KH domain containing, RNA binding | -0.00625342 |
| IFNG | interferon, gamma | -0.00623147 |
| IL15 | interleukin 15 | -0.00622032 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00620759 |
| KRT19 | keratin 19, type I | -0.00618883 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00618224 |
| EPCAM | epithelial cell adhesion molecule | -0.00615222 |
| TM4SF20 | transmembrane 4 L six family member 20 | -0.00613605 |
| GOLGA8A | golgin A8 family, member A | -0.00613083 |
| ITGB4 | integrin, beta 4 | -0.00609165 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00608361 |
| FYB1 | FYN binding protein 1 | -0.00607858 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00606409 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.00605106 |
| MLF1 | myeloid leukemia factor 1 | -0.00603346 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00602818 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00602596 |
| MT1M | metallothionein 1M | -0.00602013 |
| CHRDL1 | chordin-like 1 | -0.00600299 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00599521 |
| HBZ | hemoglobin, zeta | -0.00598619 |
| MAGEB2 | melanoma antigen family B2 | -0.00598148 |
| RTN1 | reticulon 1 | -0.00597991 |
| DIPK1A | divergent protein kinase domain 1A | -0.00597269 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00596371 |
| CLEC10A | C-type lectin domain family 10, member A | -0.00594133 |
| CD7 | CD7 molecule | -0.00590809 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.00590005 |
| TSPYL5 | TSPY-like 5 | -0.00589651 |
| CREM | cAMP responsive element modulator | -0.00586737 |
| ITK | IL2-inducible T-cell kinase | -0.00584571 |
| MSMB | microseminoprotein, beta- | -0.00584483 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00584324 |
| MMD | monocyte to macrophage differentiation-associated | -0.00583639 |
| HBB | hemoglobin, beta | -0.00583 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00580739 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00580449 |
| DCLK1 | doublecortin-like kinase 1 | -0.00579753 |
| MMP3 | matrix metallopeptidase 3 | -0.00577335 |
| PAX5 | paired box 5 | -0.00576953 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00576865 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00575679 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00575332 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00573054 |
| MAL | mal, T-cell differentiation protein | -0.00572777 |
| PERP | PERP, TP53 apoptosis effector | -0.0056834 |
| ADM | adrenomedullin | -0.0056787 |
| CCDC90B | coiled-coil domain containing 90B | -0.00566941 |
| GCH1 | GTP cyclohydrolase 1 | -0.00565704 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00564625 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00564171 |
| COMMD3 | COMM domain containing 3 | -0.00563362 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00563155 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00562572 |
| MAGEA12 | melanoma antigen family A12 | -0.00561812 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00561305 |
| AGA | aspartylglucosaminidase | -0.00561232 |
| MICALL2 | MICAL-like 2 | -0.00561077 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00560815 |
| CYCS | cytochrome c, somatic | -0.00558694 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.00558427 |
| GPX7 | glutathione peroxidase 7 | -0.00556587 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00553921 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 | -0.00553697 |
| IGSF6 | immunoglobulin superfamily, member 6 | -0.00552958 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00552759 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00552432 |
| TFEC | transcription factor EC | -0.00551341 |
| NSL1 | NSL1, MIS12 kinetochore complex component | -0.00550818 |
| SIRT5 | sirtuin 5 | -0.0054934 |
| LACTB2 | lactamase, beta 2 | -0.00547857 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | -0.00547848 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00547732 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.0054731 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.00545628 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0054344 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | -0.00542864 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00542737 |
| PPIF | peptidylprolyl isomerase F | -0.00542376 |
| PRF1 | perforin 1 (pore forming protein) | -0.00540837 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00540811 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.00540502 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.00539641 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00539558 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00538223 |
| COL10A1 | collagen, type X, alpha 1 | -0.00537158 |
| DUSP2 | dual specificity phosphatase 2 | -0.00537142 |
| IL2RB | interleukin 2 receptor, beta | -0.00536713 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00536082 |
| LYZ | lysozyme | -0.0053421 |
| CNN1 | calponin 1, basic, smooth muscle | -0.0053417 |
| MT1X | metallothionein 1X | -0.00529579 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00528963 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00528018 |
| TM4SF4 | transmembrane 4 L six family member 4 | -0.00526802 |
| DUOX2 | dual oxidase 2 | -0.00525075 |
| EVI2A | ecotropic viral integration site 2A | -0.00524858 |
| NXT2 | nuclear transport factor 2-like export factor 2 | -0.00524583 |
| AGTR1 | angiotensin II receptor, type 1 | -0.00522951 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00522108 |
| CHGB | chromogranin B | -0.0052201 |
| STAT5A | signal transducer and activator of transcription 5A | -0.00521937 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00518528 |
| KRT81 | keratin 81, type II | -0.00517894 |
| PLXNC1 | plexin C1 | -0.00517809 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | -0.00516782 |
| SELE | selectin E | -0.00516617 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0051589 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | -0.00515551 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00514916 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00514057 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | -0.00514036 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.0051389 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00513543 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 | -0.00513366 |
| HRASLS | HRAS-like suppressor | -0.00513233 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.0051232 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00512243 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00512146 |
| LIN28A | lin-28 homolog A (C. elegans) | -0.00511921 |
| NAP1L3 | nucleosome assembly protein 1-like 3 | -0.00509874 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -0.00509423 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00509177 |
| INA | internexin neuronal intermediate filament protein, alpha | -0.00509153 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | -0.00506541 |
| CLIC2 | chloride intracellular channel 2 | -0.00505657 |
| MAST2 | microtubule associated serine/threonine kinase 2 | -0.00504706 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0050418 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00504137 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00503591 |
