| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phospholipase C, gamma 1|The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5335) |
| External Link | https://ncbi.nlm.nih.gov/gene/5335 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the PLCG1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 0.0203465 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0160334 |
| PROM1 | prominin 1 | 0.0130804 |
| KRT19 | keratin 19, type I | 0.0126766 |
| PEG3 | paternally expressed 3 | 0.0122027 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0121471 |
| PCP4 | Purkinje cell protein 4 | 0.011553 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0114031 |
| TXLNA | taxilin alpha | 0.0113836 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0110657 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0108518 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0107523 |
| G0S2 | G0/G1 switch 2 | 0.0105155 |
| TPD52L1 | tumor protein D52-like 1 | 0.0104282 |
| FHL1 | four and a half LIM domains 1 | 0.00993476 |
| BMP4 | bone morphogenetic protein 4 | 0.00986598 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00980006 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00978678 |
| MMP7 | matrix metallopeptidase 7 | 0.00975369 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00958704 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00940481 |
| HHEX | hematopoietically expressed homeobox | 0.00929404 |
| ZNF652 | zinc finger protein 652 | 0.00905663 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00900803 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00896828 |
| TLE4 | transducin-like enhancer of split 4 | 0.00893189 |
| LTF | lactotransferrin | 0.00890231 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00884883 |
| TSPYL5 | TSPY-like 5 | 0.00883083 |
| LY75 | lymphocyte antigen 75 | 0.0088242 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00880513 |
| HIRA | histone cell cycle regulator | 0.00879864 |
| LYZ | lysozyme | 0.00873659 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00872132 |
| PLN | phospholamban | 0.00864333 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.00861383 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00851657 |
| NRCAM | neuronal cell adhesion molecule | 0.00847038 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00841167 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00834628 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00831919 |
| MEIS2 | Meis homeobox 2 | 0.00830327 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00830267 |
| MGP | matrix Gla protein | 0.00827401 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00826699 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00822602 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00820528 |
| COG7 | component of oligomeric golgi complex 7 | 0.0078682 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00782641 |
| ABAT | 4-aminobutyrate aminotransferase | 0.00774142 |
| RGS4 | regulator of G-protein signaling 4 | 0.00768147 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00767704 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00764875 |
| TYMS | thymidylate synthetase | 0.00752663 |
| SCG5 | secretogranin V | 0.0074708 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00743031 |
| GOLGA8A | golgin A8 family, member A | 0.0074194 |
| XYLT1 | xylosyltransferase I | 0.00738306 |
| WT1 | Wilms tumor 1 | 0.00736155 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00734137 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00727559 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00726301 |
| NID2 | nidogen 2 (osteonidogen) | 0.00724039 |
| KLF2 | Kruppel-like factor 2 | 0.00723568 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00721467 |
| GATA6 | GATA binding protein 6 | 0.00719133 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.0071863 |
| CD200 | CD200 molecule | 0.00717152 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.0071711 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00713486 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.00708341 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00707701 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00704097 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00703502 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00703048 |
| ZNF721 | zinc finger protein 721 | 0.00698455 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.00697313 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00694399 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00693482 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00688496 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00686085 |
| VCAN | versican | 0.00684834 |
| CCND2 | cyclin D2 | 0.00682182 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00678246 |
| RXYLT1 | ribitol xylosyltransferase 1 | 0.006776 |
| PLIN2 | perilipin 2 | 0.00674856 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | 0.00669438 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00666686 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.00664717 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00664503 |
| GALC | galactosylceramidase | 0.00664174 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00663893 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00661739 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00657522 |
| OGN | osteoglycin | 0.00654869 |
| ITGA8 | integrin, alpha 8 | 0.00652807 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00646426 |
| GUCY2C | guanylate cyclase 2C | 0.00645133 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00642859 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00640605 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.00638555 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00638352 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00638079 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00633176 |
| ESR1 | estrogen receptor 1 | 0.00632765 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00632484 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00631991 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00630887 |
| SNAI2 | snail family zinc finger 2 | 0.00630779 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00628248 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00627832 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00627477 |
| ANXA1 | annexin A1 | 0.00627137 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.0062683 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00624614 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00624439 |
| CST3 | cystatin C | 0.00621493 |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.00620816 |
| BEX4 | brain expressed, X-linked 4 | 0.00619493 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00619276 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00618082 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | 0.0061715 |
| RASA4 | RAS p21 protein activator 4 | 0.00614864 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00614534 |
| CD48 | CD48 molecule | 0.00614212 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00608803 |
| IFI44 | interferon-induced protein 44 | 0.0060863 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00605315 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00603903 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00603678 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.00602334 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00600872 |
| HEPH | hephaestin | 0.00600295 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.0059995 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00598105 |
| CD69 | CD69 molecule | 0.00595817 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00595803 |
| SRGN | serglycin | 0.00594514 |
| LXN | latexin | 0.00594167 |
| IER5 | immediate early response 5 | 0.00591881 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00590143 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00589957 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00589873 |
| KLF10 | Kruppel-like factor 10 | 0.00589221 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00588503 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00588247 |
| ZNF423 | zinc finger protein 423 | 0.00585865 |
| CHRDL1 | chordin-like 1 | 0.00584189 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00583269 |
| HBB | hemoglobin, beta | 0.00581655 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.00581608 |
| AEBP1 | AE binding protein 1 | 0.00581456 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.00581139 |
| TESC | tescalcin | 0.00580593 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00579928 |
| NOTCH2NL | notch 2 N-terminal like | 0.00575738 |
| FRZB | frizzled-related protein | 0.00574675 |
| RNF19B | ring finger protein 19B | 0.00572386 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.00572382 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00571697 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00570929 |
| ZNF160 | zinc finger protein 160 | 0.00570441 |
| IRF7 | interferon regulatory factor 7 | 0.00570383 |
| SYT1 | synaptotagmin I | 0.0057006 |
| TSPOAP1 | TSPO associated protein 1 | 0.00569862 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00566208 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00566172 |
| GOLGA8H | golgin A8 family, member H | 0.00565706 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.00564029 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00563487 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00562825 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00562478 |
| EFHD2 | EF-hand domain family, member D2 | 0.00562082 |
| PRKCB | protein kinase C, beta | 0.00561091 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00560071 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00559547 |
| FLNA | filamin A, alpha | 0.0055903 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0055663 |
| DCN | decorin | 0.00554678 |
| KRT23 | keratin 23, type I | 0.00554339 |
| TGFA | transforming growth factor, alpha | 0.00553046 |
| MAGED1 | melanoma antigen family D1 | 0.00552489 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0055121 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00550211 |
| PLPP3 | phospholipid phosphatase 3 | 0.00548637 |
| CD52 | CD52 molecule | 0.00545388 |
| CD38 | CD38 molecule | 0.00544517 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.0054212 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00541876 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00541796 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.00539991 |
| BAD | BCL2-associated agonist of cell death | 0.00539946 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00539939 |
| MPO | myeloperoxidase | 0.00538441 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.00538351 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00536476 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00535921 |
| SOCS1 | suppressor of cytokine signaling 1 | 0.00533821 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00532848 |
| MX1 | MX dynamin-like GTPase 1 | 0.00532702 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 | 0.00532252 |
| PDE8B | phosphodiesterase 8B | 0.00532116 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00530374 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 0.0052569 |
| IFI44L | interferon-induced protein 44-like | 0.00524579 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00524328 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00523803 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0052377 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00522925 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | 0.00522874 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00522111 |
| CFD | complement factor D (adipsin) | 0.00521465 |
| LMNB1 | lamin B1 | 0.00520045 |
| MTMR11 | myotubularin related protein 11 | 0.00519362 |
| DIXDC1 | DIX domain containing 1 | 0.00519216 |
| RFK | riboflavin kinase | 0.00518708 |
| ZNF224 | zinc finger protein 224 | 0.00517258 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | 0.0051491 |
| TSPAN5 | tetraspanin 5 | 0.00514836 |
| OAT | ornithine aminotransferase | 0.00514418 |
| ZNF91 | zinc finger protein 91 | 0.0051253 |
| COL2A1 | collagen, type II, alpha 1 | 0.005123 |
| NOTCH2 | notch 2 | 0.00512033 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00511881 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00511634 |
| STK38 | serine/threonine kinase 38 | 0.00510301 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00509639 |
| GPX2 | glutathione peroxidase 2 | 0.00508663 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.00508515 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00507618 |
| ITM2A | integral membrane protein 2A | 0.00507545 |
| APOC1 | apolipoprotein C-I | 0.00506859 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00506496 |
| CYTL1 | cytokine-like 1 | 0.00506376 |
| OLFM4 | olfactomedin 4 | 0.00505933 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00505782 |
| ZNF264 | zinc finger protein 264 | 0.00505748 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00505182 |
| DGKZ | diacylglycerol kinase, zeta | 0.00505035 |
| ZNF329 | zinc finger protein 329 | 0.00504462 |
| PEG10 | paternally expressed 10 | 0.00503903 |
| MFAP5 | microfibrillar associated protein 5 | 0.00503111 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00500951 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00500949 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00500847 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00500106 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00499378 |
| BCL2A1 | BCL2-related protein A1 | 0.00499247 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.00499206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XPO7 | exportin 7 | -0.0180126 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.0145476 |
| S100A7 | S100 calcium binding protein A7 | -0.0126849 |
| COPS7A | COP9 signalosome subunit 7A | -0.0112109 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | -0.0110986 |
| KRT17 | keratin 17, type I | -0.0110722 |
| S100A2 | S100 calcium binding protein A2 | -0.0104897 |
| NVL | nuclear VCP-like | -0.00982804 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00970632 |
| ZNF395 | zinc finger protein 395 | -0.00966067 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0096212 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.00948615 |
| DEFB1 | defensin, beta 1 | -0.00924692 |
| KRT1 | keratin 1, type II | -0.0091331 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00907859 |
| L1CAM | L1 cell adhesion molecule | -0.00903097 |
| DSP | desmoplakin | -0.00902352 |
| CHN1 | chimerin 1 | -0.00896083 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00888352 |
| SPRR1B | small proline-rich protein 1B | -0.0082867 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00826084 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.00824126 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00815237 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00799751 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00797815 |
| DAXX | death-domain associated protein | -0.00794374 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.00787347 |
| TRIM29 | tripartite motif containing 29 | -0.00785746 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00784041 |
| PDLIM1 | PDZ and LIM domain 1 | -0.00778183 |
| DSG1 | desmoglein 1 | -0.00776489 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00774563 |
| GNAS | GNAS complex locus | -0.00755205 |
| SFN | stratifin | -0.00746984 |
| PLAT | plasminogen activator, tissue | -0.007307 |
| TCTA | T-cell leukemia translocation altered | -0.00715122 |
| KRT6A | keratin 6A, type II | -0.0071296 |
| LOR | loricrin | -0.00705432 |
| RGCC | regulator of cell cycle | -0.00701494 |
| SPRR2B | small proline-rich protein 2B | -0.00698909 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00692121 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00688857 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00673848 |
| ODC1 | ornithine decarboxylase 1 | -0.0066636 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00663009 |
| PRDX2 | peroxiredoxin 2 | -0.00658887 |
| STC1 | stanniocalcin 1 | -0.00657069 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.00656481 |
| SHROOM2 | shroom family member 2 | -0.00653829 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00652513 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0065148 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | -0.00649785 |
| SIK1 | salt-inducible kinase 1 | -0.00643988 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00642205 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00638296 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00636512 |
| CSRP2 | cysteine and glycine-rich protein 2 | -0.00636376 |
| NDRG1 | N-myc downstream regulated 1 | -0.00633363 |
| RETREG1 | reticulophagy regulator 1 | -0.00632264 |
| GLO1 | glyoxalase I | -0.00630461 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00629711 |
| SPRR1A | small proline-rich protein 1A | -0.00629484 |
| CLTB | clathrin, light chain B | -0.00622841 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.0061276 |
| WDR26 | WD repeat domain 26 | -0.00612397 |
| CDA | cytidine deaminase | -0.00612055 |
| KRT2 | keratin 2, type II | -0.00611088 |
| PODXL | podocalyxin-like | -0.00608725 |
| KRT10 | keratin 10, type I | -0.00607159 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00603798 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.00603605 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00601941 |
| SCEL | sciellin | -0.00598817 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00597256 |
| KRT5 | keratin 5, type II | -0.0059724 |
| TMEM45A | transmembrane protein 45A | -0.00596881 |
| ASS1 | argininosuccinate synthase 1 | -0.00591494 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00591343 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.00587768 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00587587 |
| FABP1 | fatty acid binding protein 1, liver | -0.00585517 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00585236 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00583459 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00582425 |
| MAL | mal, T-cell differentiation protein | -0.00582032 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00581568 |
| FBXO28 | F-box protein 28 | -0.00581557 |
| XBP1 | X-box binding protein 1 | -0.00581135 |
| KRT14 | keratin 14, type I | -0.00581015 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00579614 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00579532 |
| FAM13A | family with sequence similarity 13, member A | -0.0057915 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00578402 |
| GPC1 | glypican 1 | -0.00577423 |
| S100A9 | S100 calcium binding protein A9 | -0.00577401 |
| ADIPOR2 | adiponectin receptor 2 | -0.00576746 |
| ENSA | endosulfine alpha | -0.00576129 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | -0.00575559 |
| TUBB3 | tubulin, beta 3 class III | -0.00573071 |
| PEX19 | peroxisomal biogenesis factor 19 | -0.00572825 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.00571959 |
| TPI1 | triosephosphate isomerase 1 | -0.00570803 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00570001 |
| OLFM1 | olfactomedin 1 | -0.00567692 |
| KLF6 | Kruppel-like factor 6 | -0.0056703 |
| FASN | fatty acid synthase | -0.00566934 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00566838 |
| CIT | citron rho-interacting serine/threonine kinase | -0.00560244 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00559144 |
| BAG1 | BCL2-associated athanogene | -0.00556506 |
| SFTPD | surfactant protein D | -0.00555968 |
| CD99 | CD99 molecule | -0.00552973 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00551035 |
| KRT6B | keratin 6B, type II | -0.00549162 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00548349 |
| TMEM176B | transmembrane protein 176B | -0.00548336 |
| EXOC5 | exocyst complex component 5 | -0.00545893 |
| CALML3 | calmodulin-like 3 | -0.00545365 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -0.00541294 |
| YBX3 | Y box binding protein 3 | -0.00540155 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00539296 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00536847 |
| SRM | spermidine synthase | -0.00533553 |
| SNX13 | sorting nexin 13 | -0.00532454 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00531655 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00530979 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00530617 |
| HSPB1 | heat shock 27kDa protein 1 | -0.00529386 |
| CTSV | cathepsin V | -0.00528919 |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | -0.00527448 |
| PLLP | plasmolipin | -0.00526337 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00525586 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00524116 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | -0.00523948 |
| DLX2 | distal-less homeobox 2 | -0.00521161 |
| RDX | radixin | -0.00520352 |
| TAPBP | TAP binding protein (tapasin) | -0.00519823 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0051969 |
| MCM5 | minichromosome maintenance complex component 5 | -0.0051964 |
| CDCA3 | cell division cycle associated 3 | -0.00518141 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00517352 |
| TNS3 | tensin 3 | -0.00515632 |
| HAL | histidine ammonia-lyase | -0.00515366 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00513345 |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | -0.00512742 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.00511071 |
| RCAN1 | regulator of calcineurin 1 | -0.00509528 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0050233 |
| ARG1 | arginase 1 | -0.00502143 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -0.00501266 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00501255 |
| CP | ceruloplasmin (ferroxidase) | -0.00501165 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.00501025 |
| RRAGA | Ras-related GTP binding A | -0.00498782 |
| DOCK1 | dedicator of cytokinesis 1 | -0.00496922 |
| DST | dystonin | -0.00496048 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00493372 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -0.00491986 |
| ZBED1 | zinc finger, BED-type containing 1 | -0.00491527 |
| CD81 | CD81 molecule | -0.00491296 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00490202 |
| ENO1 | enolase 1, (alpha) | -0.00489612 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.004883 |
| SELENBP1 | selenium binding protein 1 | -0.00488025 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00486941 |
| CLTC | clathrin, heavy chain (Hc) | -0.00486539 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00486035 |
| SPRR3 | small proline-rich protein 3 | -0.00485147 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | -0.00484439 |
| PPL | periplakin | -0.00482871 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00482532 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.00480343 |
| MGLL | monoglyceride lipase | -0.00479241 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.00479223 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 | -0.00478019 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00476024 |
| PKM | pyruvate kinase, muscle | -0.00475651 |
| RHCG | Rh family, C glycoprotein | -0.00473548 |
| OBSL1 | obscurin-like 1 | -0.00473493 |
| COL7A1 | collagen, type VII, alpha 1 | -0.00473167 |
| H2AFV | H2A histone family, member V | -0.00472279 |
| EMP2 | epithelial membrane protein 2 | -0.00472078 |
| CRCT1 | cysteine-rich C-terminal 1 | -0.00470712 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.00470516 |
| HOMER2 | homer scaffolding protein 2 | -0.00470299 |
| AVPI1 | arginine vasopressin-induced 1 | -0.00469405 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00468964 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | -0.00468831 |
| CD9 | CD9 molecule | -0.00468782 |
| OGDHL | oxoglutarate dehydrogenase-like | -0.00468294 |
| NAXD | NAD(P)HX dehydratase | -0.00468289 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00467373 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0046703 |
| KRT16 | keratin 16, type I | -0.0046621 |
| KIF1B | kinesin family member 1B | -0.00464168 |
| IVL | involucrin | -0.00464095 |
| SATB2 | SATB homeobox 2 | -0.00463687 |
| GNMT | glycine N-methyltransferase | -0.00463669 |
| C3 | complement component 3 | -0.0046358 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.00462691 |
| SLC17A4 | solute carrier family 17, member 4 | -0.00461709 |
| RBM5 | RNA binding motif protein 5 | -0.00460696 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00459963 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00458858 |
| NELFE | negative elongation factor complex member E | -0.00457243 |
| CDSN | corneodesmosin | -0.00456729 |
| GLUD2 | glutamate dehydrogenase 2 | -0.00456668 |
| PTGES | prostaglandin E synthase | -0.00456358 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00454259 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00453646 |
| CEL | carboxyl ester lipase | -0.00453054 |
| SHTN1 | shootin 1 | -0.00452061 |
| PEX5 | peroxisomal biogenesis factor 5 | -0.00451634 |
| SDC2 | syndecan 2 | -0.0045029 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00449613 |
| TPX2 | TPX2, microtubule-associated | -0.00449391 |
| PLK1 | polo-like kinase 1 | -0.00449068 |
| ZIC1 | Zic family member 1 | -0.00449052 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0044852 |
| C4BPA | complement component 4 binding protein, alpha | -0.00448152 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00447242 |
| PITRM1 | pitrilysin metallopeptidase 1 | -0.00445012 |
| FLOT1 | flotillin 1 | -0.00444718 |
| C21ORF33 | chromosome 21 open reading frame 33 | -0.00444454 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00444444 |
| S100A10 | S100 calcium binding protein A10 | -0.00444135 |
| SEPTIN10 | septin 10 | -0.00443432 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00442948 |
| FZD5 | frizzled class receptor 5 | -0.0044146 |
| CLIC3 | chloride intracellular channel 3 | -0.00440574 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | -0.00439759 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.00439432 |
| CD8A | CD8a molecule | -0.00439386 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.00439159 |
| QDPR | quinoid dihydropteridine reductase | -0.00438934 |
| ELP3 | elongator acetyltransferase complex subunit 3 | -0.00438359 |
| NOTCH3 | notch 3 | -0.00437002 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0043683 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00435622 |
| CENPE | centromere protein E, 312kDa | -0.00435534 |
| PCID2 | PCI domain containing 2 | -0.00434446 |
| PRDX1 | peroxiredoxin 1 | -0.00434163 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00434093 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0043339 |
| CLCA4 | chloride channel accessory 4 | -0.00432808 |
| ATP6V1B2 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 | -0.00432251 |
| PDZD2 | PDZ domain containing 2 | -0.00431303 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.00430973 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | -0.00430812 |
