| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | phospholipase C, gamma 2 (phosphatidylinositol-specific)|The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 5336) |
| External Link | https://ncbi.nlm.nih.gov/gene/5336 |
| Similar Terms | |
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498 genes differentially expressed following the PLCG2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0153128 |
| PRDX2 | peroxiredoxin 2 | 0.0149485 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.0124085 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0118163 |
| RTN2 | reticulon 2 | 0.0116114 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0113897 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0112971 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0112651 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0108185 |
| PDLIM3 | PDZ and LIM domain 3 | 0.0106173 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.0105646 |
| OLFM4 | olfactomedin 4 | 0.0105254 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.0103606 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0103288 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.010304 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0101383 |
| GAS1 | growth arrest-specific 1 | 0.00996688 |
| FASN | fatty acid synthase | 0.00994783 |
| LMNB2 | lamin B2 | 0.00972387 |
| ANXA6 | annexin A6 | 0.00971103 |
| COL3A1 | collagen, type III, alpha 1 | 0.00967084 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.0096368 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00963633 |
| TMSB15A | thymosin beta 15a | 0.00943976 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00941915 |
| TSPAN12 | tetraspanin 12 | 0.00932227 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00930933 |
| HMG20B | high mobility group 20B | 0.00914597 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00913633 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0090992 |
| PDZK1 | PDZ domain containing 1 | 0.00909135 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0090627 |
| ABHD17A | abhydrolase domain containing 17A | 0.00893512 |
| KIF20A | kinesin family member 20A | 0.0089069 |
| MTA1 | metastasis associated 1 | 0.00889242 |
| SDC2 | syndecan 2 | 0.00885716 |
| AGR2 | anterior gradient 2 | 0.00874319 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0087364 |
| MAP7 | microtubule-associated protein 7 | 0.00870836 |
| CDC20 | cell division cycle 20 | 0.00853475 |
| FOXF1 | forkhead box F1 | 0.00842335 |
| CHKB | choline kinase beta | 0.00840083 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00835673 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0083276 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00830344 |
| METRN | meteorin, glial cell differentiation regulator | 0.00823489 |
| CA2 | carbonic anhydrase II | 0.00821497 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00820951 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00812453 |
| PKM | pyruvate kinase, muscle | 0.00806967 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.00805688 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.00804722 |
| CCNF | cyclin F | 0.00802285 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00799149 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00796068 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00795675 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00785936 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00782993 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00773804 |
| NES | nestin | 0.00769914 |
| DES | desmin | 0.00769194 |
| MCM5 | minichromosome maintenance complex component 5 | 0.00763814 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00762354 |
| SLC2A4RG | SLC2A4 regulator | 0.00758023 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.00757405 |
| NTS | neurotensin | 0.00749288 |
| PTCH1 | patched 1 | 0.00748353 |
| PCNA | proliferating cell nuclear antigen | 0.00747557 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00747555 |
| TLCD3A | TLC domain containing 3A | 0.00747002 |
| ACTC1 | actin, alpha, cardiac muscle 1 | 0.00743062 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00738738 |
| RAPSN | receptor-associated protein of the synapse | 0.00736457 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | 0.00734963 |
| DGKZ | diacylglycerol kinase, zeta | 0.00734146 |
| RGS5 | regulator of G-protein signaling 5 | 0.00732757 |
| CCND1 | cyclin D1 | 0.00732384 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.00731235 |
| OLFM1 | olfactomedin 1 | 0.00729103 |
| TNC | tenascin C | 0.00728839 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0072683 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00726525 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.00724089 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00724086 |
| FSTL1 | follistatin-like 1 | 0.0072324 |
| PLAT | plasminogen activator, tissue | 0.00723021 |
| ELANE | elastase, neutrophil expressed | 0.00720499 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00717877 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00715693 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00712009 |
| PCLAF | PCNA clamp associated factor | 0.00708885 |
| TLE2 | transducin-like enhancer of split 2 | 0.00705065 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00704634 |
| NANOG | Nanog homeobox | 0.00704037 |
| TOX3 | TOX high mobility group box family member 3 | 0.00701968 |
| LOXL1 | lysyl oxidase-like 1 | 0.0070084 |
| HOXC6 | homeobox C6 | 0.00699594 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.00696106 |
| TMEM38B | transmembrane protein 38B | 0.00696045 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00695107 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00694742 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.00690076 |
| DUT | deoxyuridine triphosphatase | 0.00689906 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | 0.00685667 |
| PRC1 | protein regulator of cytokinesis 1 | 0.00684176 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00683786 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00683684 |
| CTSG | cathepsin G | 0.00680668 |
| AOC1 | amine oxidase, copper containing 1 | 0.00677425 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.00675692 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00675482 |
| IPO5 | importin 5 | 0.00672918 |
| MAPT | microtubule-associated protein tau | 0.00672247 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00671917 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.00671053 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00670932 |
| KLHDC3 | kelch domain containing 3 | 0.00668749 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00666759 |
| PITX1 | paired-like homeodomain 1 | 0.00666046 |
| HDAC6 | histone deacetylase 6 | 0.00665236 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00665135 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0066438 |
| CFD | complement factor D (adipsin) | 0.00664357 |
| COL5A1 | collagen, type V, alpha 1 | 0.00664019 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | 0.00662996 |
| TFF1 | trefoil factor 1 | 0.00662611 |
| AZU1 | azurocidin 1 | 0.00662358 |
| PMP22 | peripheral myelin protein 22 | 0.0065874 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00657535 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00656491 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | 0.00650743 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.00644666 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00643921 |
| SLC25A11 | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 0.00643487 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00642755 |
| CDCA4 | cell division cycle associated 4 | 0.00642259 |
| CTBP1 | C-terminal binding protein 1 | 0.006416 |
| FLNC | filamin C, gamma | 0.00638457 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.00636993 |
| PIH1D1 | PIH1 domain containing 1 | 0.0063679 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00636362 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00634563 |
| LONP1 | lon peptidase 1, mitochondrial | 0.00633434 |
| LBR | lamin B receptor | 0.0063233 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00631067 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.00629835 |
| TTC38 | tetratricopeptide repeat domain 38 | 0.00629718 |
| NUP107 | nucleoporin 107kDa | 0.00628067 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.00627955 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.0062701 |
| HMGB2 | high mobility group box 2 | 0.00625632 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00625333 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | 0.0062532 |
| HMGB1 | high mobility group box 1 | 0.00624875 |
| LMNB1 | lamin B1 | 0.0062468 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 0.00624526 |
| WDR7 | WD repeat domain 7 | 0.00624525 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00624224 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.00622229 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00619239 |
| THOP1 | thimet oligopeptidase 1 | 0.00617972 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 0.00617774 |
| GTSE1 | G-2 and S-phase expressed 1 | 0.00616502 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | 0.00613761 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00612789 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.00612574 |
| DAPK1 | death-associated protein kinase 1 | 0.00611713 |
| H1-10 | H1.10 linker histone | 0.00611632 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00611205 |
| HMGB3 | high mobility group box 3 | 0.00611104 |
| FOXM1 | forkhead box M1 | 0.00610154 |
| NELFB | negative elongation factor complex member B | 0.006094 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00608896 |
| FEN1 | flap structure-specific endonuclease 1 | 0.00608557 |
| B3GNT1 | 0.00607306 | |
| KHK | ketohexokinase (fructokinase) | 0.00605431 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | 0.00603649 |
| KLHL23 | kelch-like family member 23 | 0.00603576 |
| MMP12 | matrix metallopeptidase 12 | 0.00603268 |
| ECI1 | enoyl-CoA delta isomerase 1 | 0.00601226 |
| CD320 | CD320 molecule | 0.00600984 |
| CYC1 | cytochrome c-1 | 0.00599496 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00599284 |
| DHFR | dihydrofolate reductase | 0.00597335 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.0059633 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.00594949 |
| BIN1 | bridging integrator 1 | 0.00591768 |
| GPAA1 | glycosylphosphatidylinositol anchor attachment 1 | 0.00591517 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00590784 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 | 0.00589331 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00585589 |
| TMEM47 | transmembrane protein 47 | 0.0058519 |
| RTL8C | retrotransposon Gag like 8C | 0.00585107 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00584864 |
| GLO1 | glyoxalase I | 0.00583012 |
| AURKA | aurora kinase A | 0.00582327 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00582189 |
| SDF4 | stromal cell derived factor 4 | 0.00581832 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | 0.00581589 |
| OBSL1 | obscurin-like 1 | 0.00579944 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.00577669 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00576808 |
| MACROD1 | MACRO domain containing 1 | 0.00574284 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.0057334 |
| CENPBD1P1 | CENPB DNA-binding domains containing 1 pseudogene 1 | 0.00572707 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00572045 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.00571747 |
| MSX1 | msh homeobox 1 | 0.00570993 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00570918 |
| ISL1 | ISL LIM homeobox 1 | 0.00570004 |
| CIT | citron rho-interacting serine/threonine kinase | 0.00569796 |
| NUP85 | nucleoporin 85kDa | 0.00567179 |
| MLEC | malectin | 0.00566006 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00563506 |
| ACKR3 | atypical chemokine receptor 3 | 0.00563436 |
| RCAN2 | regulator of calcineurin 2 | 0.00563131 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.00562788 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00562074 |
| TK1 | thymidine kinase 1, soluble | 0.00561183 |
| EFNB2 | ephrin-B2 | 0.00559698 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00558044 |
| SHOX2 | short stature homeobox 2 | 0.00557347 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00556396 |
| PLN | phospholamban | 0.00556392 |
| NINJ2 | ninjurin 2 | 0.00556358 |
| PEG3 | paternally expressed 3 | 0.00555788 |
| GPS1 | G protein pathway suppressor 1 | 0.00555729 |
| SNRPA | small nuclear ribonucleoprotein polypeptide A | 0.00554924 |
| KAZN | kazrin, periplakin interacting protein | 0.00554624 |
| RABL6 | RAB, member RAS oncogene family-like 6 | 0.0055454 |
| FUS | FUS RNA binding protein | 0.0055379 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | 0.00553061 |
| PLD3 | phospholipase D family, member 3 | 0.00553012 |
| TARDBP | TAR DNA binding protein | 0.00552972 |
| SELENOW | selenoprotein W | 0.00552351 |
| TUBB4B | tubulin, beta 4B class IVb | 0.00552241 |
| CNTNAP2 | contactin associated protein-like 2 | 0.00549032 |
| MRPL12 | mitochondrial ribosomal protein L12 | 0.00548871 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.00547816 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00547634 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00547196 |
| VARS | valyl-tRNA synthetase | 0.00545885 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 0.00545714 |
| INTS1 | integrator complex subunit 1 | 0.005454 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 0.00544879 |
| PLPP3 | phospholipid phosphatase 3 | 0.00544794 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.0054461 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.00544386 |
| TMEM109 | transmembrane protein 109 | 0.00543927 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00543781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0206868 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.0179552 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0174719 |
| ANXA1 | annexin A1 | -0.0162829 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0157733 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0157233 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0141535 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0137959 |
| KRT14 | keratin 14, type I | -0.0137231 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.0136643 |
| MX1 | MX dynamin-like GTPase 1 | -0.0132559 |
| IER5 | immediate early response 5 | -0.0126017 |
| PEG10 | paternally expressed 10 | -0.0124682 |
| HIST1H2AC | histone cluster 1, H2ac | -0.0123124 |
| MYO1B | myosin IB | -0.0123079 |
| RGCC | regulator of cell cycle | -0.0119501 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.0117962 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0115015 |
| IFI44 | interferon-induced protein 44 | -0.0113574 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.0112589 |
| ATF3 | activating transcription factor 3 | -0.0112396 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0109378 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0109152 |
| CCN2 | cellular communication network factor 2 | -0.0107661 |
| HIST1H2BD | histone cluster 1, H2bd | -0.0107643 |
| INHBA | inhibin, beta A | -0.0107509 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0106565 |
| CSTA | cystatin A (stefin A) | -0.0105465 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0105059 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | -0.010495 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.0104359 |
| SP100 | SP100 nuclear antigen | -0.0104111 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0103615 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0103394 |
| TRIM22 | tripartite motif containing 22 | -0.0102495 |
| EMP1 | epithelial membrane protein 1 | -0.0102265 |
| MT1X | metallothionein 1X | -0.0102001 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0101907 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0101778 |
| LY96 | lymphocyte antigen 96 | -0.0101633 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.010128 |
| KRT15 | keratin 15, type I | -0.0100331 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0100199 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00995658 |
| XIC | X chromosome inactivation center | -0.00988822 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.00987956 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.00984617 |
| BTG3 | BTG family, member 3 | -0.00982676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00982112 |
| SYT1 | synaptotagmin I | -0.0097971 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00978197 |
| MT1G | metallothionein 1G | -0.00977365 |
| LAMC2 | laminin, gamma 2 | -0.00977158 |
| KYNU | kynureninase | -0.00974897 |
| MCL1 | myeloid cell leukemia 1 | -0.00960865 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.00957714 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00956124 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.00955296 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00951724 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00947932 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.00947685 |
| TPD52L1 | tumor protein D52-like 1 | -0.00946494 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.0094391 |
| FN1 | fibronectin 1 | -0.00941853 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00938774 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00936144 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00930546 |
| S100A11 | S100 calcium binding protein A11 | -0.00929432 |
| HMOX1 | heme oxygenase 1 | -0.00924232 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00923126 |
| ZMAT3 | zinc finger, matrin-type 3 | -0.00920845 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00918529 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00915607 |
| AIM2 | absent in melanoma 2 | -0.0091179 |
| FHL2 | four and a half LIM domains 2 | -0.00909629 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.00902488 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00901383 |
| IPO13 | importin 13 | -0.00894982 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0088241 |
| MAL | mal, T-cell differentiation protein | -0.00882311 |
| RGS10 | regulator of G-protein signaling 10 | -0.00881483 |
| S100A10 | S100 calcium binding protein A10 | -0.0088133 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0087587 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00873028 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00872217 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00867043 |
| MYO1C | myosin IC | -0.00866591 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00865266 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00859325 |
| KLK10 | kallikrein-related peptidase 10 | -0.00858602 |
| SERINC5 | serine incorporator 5 | -0.00853673 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00852056 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00851014 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -0.00850223 |
| HDAC9 | histone deacetylase 9 | -0.00849812 |
| SGCE | sarcoglycan, epsilon | -0.00849141 |
| REEP5 | receptor accessory protein 5 | -0.00847112 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00832909 |
| EGR2 | early growth response 2 | -0.00832135 |
| SP110 | SP110 nuclear body protein | -0.00830586 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00830334 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00828077 |
| ADIRF | adipogenesis regulatory factor | -0.00827746 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00822421 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00820355 |
| PRAME | preferentially expressed antigen in melanoma | -0.0081913 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00816426 |
| EVI2A | ecotropic viral integration site 2A | -0.00808277 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00805886 |
| RTCA | RNA 3'-terminal phosphate cyclase | -0.00802327 |
| CALCRL | calcitonin receptor-like | -0.00801786 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00800666 |
| TCTA | T-cell leukemia translocation altered | -0.00798382 |
| MT2A | metallothionein 2A | -0.0078943 |
| STON1 | stonin 1 | -0.00787755 |
| CADM1 | cell adhesion molecule 1 | -0.0078734 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00786268 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00780976 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | -0.00778735 |
| ABHD4 | abhydrolase domain containing 4 | -0.00777187 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0077663 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00776161 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | -0.00775115 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.0077344 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00772054 |
| IL1B | interleukin 1, beta | -0.00770332 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.007666 |
| KRT5 | keratin 5, type II | -0.00766481 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00765016 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.00762503 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0076205 |
| CRYAB | crystallin, alpha B | -0.00761233 |
| CD59 | CD59 molecule, complement regulatory protein | -0.00757591 |
| MRPL18 | mitochondrial ribosomal protein L18 | -0.00756447 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00754427 |
| KLHL24 | kelch-like family member 24 | -0.00753254 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00752912 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00751877 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00751032 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00749673 |
| PRSS23 | protease, serine, 23 | -0.00747682 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00747302 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.00746837 |
| EGR1 | early growth response 1 | -0.00745394 |
| IFI44L | interferon-induced protein 44-like | -0.00744787 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00739472 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00739021 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00737674 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 | -0.00737447 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00735423 |
| CNTN1 | contactin 1 | -0.00735303 |
| APOC1 | apolipoprotein C-I | -0.00734434 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00734427 |
| IL1R2 | interleukin 1 receptor, type II | -0.00734292 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00731289 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00730699 |
| ASS1 | argininosuccinate synthase 1 | -0.00730393 |
| PTHLH | parathyroid hormone-like hormone | -0.00729606 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.00729294 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | -0.00728958 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | -0.00728662 |
| CORO1C | coronin, actin binding protein, 1C | -0.00728144 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00722608 |
| RPS27L | ribosomal protein S27-like | -0.00722222 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -0.00721546 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00721105 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00718272 |
| MT1HL1 | metallothionein 1H-like 1 | -0.00717379 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00716829 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00715846 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00715629 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00713735 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00711868 |
| PSAP | prosaposin | -0.00709082 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00708949 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00706429 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00706085 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00705296 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00701322 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.006998 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00699021 |
| GAS7 | growth arrest-specific 7 | -0.00697771 |
| CD93 | CD93 molecule | -0.00696901 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.00693502 |
| FOLR1 | folate receptor 1 (adult) | -0.00692747 |
| DGKA | diacylglycerol kinase, alpha 80kDa | -0.00692735 |
| ABLIM1 | actin binding LIM protein 1 | -0.00692331 |
| APOD | apolipoprotein D | -0.00691896 |
| RHOB | ras homolog family member B | -0.00691613 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00690334 |
| VAMP5 | vesicle-associated membrane protein 5 | -0.00689364 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | -0.00688463 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.00688013 |
| ICOS | inducible T-cell co-stimulator | -0.00687603 |
| SC5D | sterol-C5-desaturase | -0.00686509 |
| MAGEA3 | melanoma antigen family A3 | -0.00685388 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00685326 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00684363 |
| PIP | prolactin-induced protein | -0.00683886 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0068338 |
| MT1H | metallothionein 1H | -0.00683021 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | -0.00682296 |
| SOCS2 | suppressor of cytokine signaling 2 | -0.00679652 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00678034 |
| KLK5 | kallikrein-related peptidase 5 | -0.00676213 |
| RTP4 | receptor (chemosensory) transporter protein 4 | -0.0067562 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00675295 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00674414 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | -0.0067032 |
| CCNA2 | cyclin A2 | -0.00670313 |
| MFSD1 | major facilitator superfamily domain containing 1 | -0.00669184 |
| INHBB | inhibin, beta B | -0.00668822 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00666642 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00665333 |
| KRT81 | keratin 81, type II | -0.00662773 |
| CLIC5 | chloride intracellular channel 5 | -0.00662527 |
| BAG3 | BCL2-associated athanogene 3 | -0.00661452 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00660641 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00659052 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.0065841 |
| BTG2 | BTG family, member 2 | -0.00657762 |
| KRT7 | keratin 7, type II | -0.00655613 |
| KIAA0355 | KIAA0355 | -0.00654853 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00651057 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00649531 |
| MAGEA4 | melanoma antigen family A4 | -0.00649183 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00648314 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0064818 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00648067 |
| RAB9A | RAB9A, member RAS oncogene family | -0.00647502 |
| ELMO1 | engulfment and cell motility 1 | -0.00647218 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00647197 |
| TGFA | transforming growth factor, alpha | -0.0064575 |
| MYOF | myoferlin | -0.00645585 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.00645231 |
| LPIN1 | lipin 1 | -0.00642857 |
| UBFD1 | ubiquitin family domain containing 1 | -0.00638408 |
| CYB5R1 | cytochrome b5 reductase 1 | -0.00636061 |
| ATOX1 | antioxidant 1 copper chaperone | -0.00635067 |
| CCDC6 | coiled-coil domain containing 6 | -0.00634247 |
| CAV2 | caveolin 2 | -0.00633527 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00633037 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.00632129 |
| ODC1 | ornithine decarboxylase 1 | -0.00631534 |
| HECA | headcase homolog (Drosophila) | -0.00630487 |
| MX2 | MX dynamin-like GTPase 2 | -0.00629805 |
| CD86 | CD86 molecule | -0.00629503 |
| AREG | amphiregulin | -0.00629356 |
