PLK1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description polo-like kinase 1| (NCBI Entrez Gene Database, 5347)
External Link https://ncbi.nlm.nih.gov/gene/5347
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Genes

500 genes differentially expressed following the PLK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HIST1H2AC histone cluster 1, H2ac 0.0225318
CENPE centromere protein E, 312kDa 0.0224902
HIST1H2BD histone cluster 1, H2bd 0.0218185
BAMBI BMP and activin membrane-bound inhibitor 0.0188512
CDC20 cell division cycle 20 0.018226
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.0171438
KIF14 kinesin family member 14 0.0167981
HIST1H2BK histone cluster 1, H2bk 0.0161464
KIF20A kinesin family member 20A 0.0161418
AOC1 amine oxidase, copper containing 1 0.0161129
HMOX1 heme oxygenase 1 0.0158662
AURKA aurora kinase A 0.0152938
PSRC1 proline/serine-rich coiled-coil 1 0.0152809
MYB v-myb avian myeloblastosis viral oncogene homolog 0.015186
NT5E 5'-nucleotidase, ecto (CD73) 0.0149943
CD9 CD9 molecule 0.0148676
SFRP1 secreted frizzled-related protein 1 0.0147423
PLK2 polo-like kinase 2 0.0147159
XIC X chromosome inactivation center 0.0145107
KRT23 keratin 23, type I 0.0141502
AREG amphiregulin 0.0140858
MT1G metallothionein 1G 0.013933
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.0137353
IGFBP5 insulin-like growth factor binding protein 5 0.0136918
MT1X metallothionein 1X 0.0133348
H1-2 H1.2 linker histone, cluster member 0.013282
NDC80 NDC80 kinetochore complex component 0.0132641
ALCAM activated leukocyte cell adhesion molecule 0.0131704
KLK10 kallikrein-related peptidase 10 0.0130423
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0129722
MT1E metallothionein 1E 0.0128117
PITX3 paired-like homeodomain 3 0.0128035
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.0124972
SOX9 SRY (sex determining region Y)-box 9 0.0123737
ANPEP alanyl (membrane) aminopeptidase 0.0122045
CTSD cathepsin D 0.0121693
IFI27 interferon, alpha-inducible protein 27 0.0121421
KRT14 keratin 14, type I 0.012057
CCNB2 cyclin B2 0.0120503
RTCA RNA 3'-terminal phosphate cyclase 0.0119593
KLK11 kallikrein-related peptidase 11 0.0119506
STC2 stanniocalcin 2 0.0118456
OXTR oxytocin receptor 0.0117321
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.0117187
SHB Src homology 2 domain containing adaptor protein B 0.0116661
TWIST1 twist family bHLH transcription factor 1 0.0115502
BCL2A1 BCL2-related protein A1 0.0115379
LGALS3 lectin, galactoside-binding, soluble, 3 0.0115327
MT1F metallothionein 1F 0.0114624
PTPRO protein tyrosine phosphatase, receptor type, O 0.011412
OLFM4 olfactomedin 4 0.011379
SSX1 synovial sarcoma, X breakpoint 1 0.0113089
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.0112083
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0111737
CEP55 centrosomal protein 55kDa 0.0111196
CAPG capping protein (actin filament), gelsolin-like 0.0111064
ACTN1 actinin, alpha 1 0.01106
GREB1 growth regulation by estrogen in breast cancer 1 0.0110287
CKS2 CDC28 protein kinase regulatory subunit 2 0.010955
HSPA2 heat shock 70kDa protein 2 0.0109027
TRPS1 trichorhinophalangeal syndrome I 0.0108422
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.0108084
HTRA1 HtrA serine peptidase 1 0.0107938
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.010717
MME membrane metallo-endopeptidase 0.0107163
TTK TTK protein kinase 0.0106548
SCPEP1 serine carboxypeptidase 1 0.0105763
KIAA0226L KIAA0226-like 0.0105502
S100A12 S100 calcium binding protein A12 0.0105457
ITGB4 integrin, beta 4 0.0105441
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.0105318
GPSM2 G-protein signaling modulator 2 0.0105264
KLF5 Kruppel-like factor 5 (intestinal) 0.0104836
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.0104703
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.0104653
NCF2 neutrophil cytosolic factor 2 0.0104617
PADI2 peptidyl arginine deiminase, type II 0.0104394
SATB2 SATB homeobox 2 0.0104191
CLDN3 claudin 3 0.0103965
IL1B interleukin 1, beta 0.0102542
FTH1 ferritin, heavy polypeptide 1 0.0102384
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.0102324
SDC4 syndecan 4 0.0102062
SMAD3 SMAD family member 3 0.0102005
ALOX15B arachidonate 15-lipoxygenase, type B 0.0101987
SNAI2 snail family zinc finger 2 0.0101925
AUTS2 autism susceptibility candidate 2 0.0101207
GM2A GM2 ganglioside activator 0.0101174
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.010075
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.0100485
ANKRD11 ankyrin repeat domain 11 0.0100165
CENPF centromere protein F, 350/400kDa 0.00998515
IER5 immediate early response 5 0.00993467
CRYAB crystallin, alpha B 0.00993371
LCN2 lipocalin 2 0.00986382
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00983494
EIF5B eukaryotic translation initiation factor 5B 0.0098201
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00981937
CA12 carbonic anhydrase XII 0.00980989
NEK2 NIMA-related kinase 2 0.00977931
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00975213
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.0097474
SLC22A18 solute carrier family 22, member 18 0.00973342
LTF lactotransferrin 0.00960721
FOXD1 forkhead box D1 0.00959318
MICB MHC class I polypeptide-related sequence B 0.00956047
IGFBP6 insulin-like growth factor binding protein 6 0.00955443
JMJD6 jumonji domain containing 6 0.00954007
LAMP1 lysosomal-associated membrane protein 1 0.00953072
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00951788
HIST1H2BH histone cluster 1, H2bh 0.00951171
CCNA1 cyclin A1 0.00950613
CCDC88A coiled-coil domain containing 88A 0.00950322
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.009499
VPREB1 pre-B lymphocyte 1 0.0094742
PLAU plasminogen activator, urokinase 0.00944482
PLBD1 phospholipase B domain containing 1 0.00944398
CEMIP cell migration inducing protein, hyaluronan binding 0.00938484
EGF epidermal growth factor 0.00936741
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00936695
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00936423
CCNG2 cyclin G2 0.00934869
JPT1 Jupiter microtubule associated homolog 1 0.00931787
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00926308
MT1HL1 metallothionein 1H-like 1 0.00925347
FBN2 fibrillin 2 0.00923188
PTN pleiotrophin 0.00922726
DEFA4 defensin, alpha 4, corticostatin 0.00921984
TIMP1 TIMP metallopeptidase inhibitor 1 0.00918276
RND3 Rho family GTPase 3 0.0091528
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.00915226
IQCG IQ motif containing G 0.00914724
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00913968
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00913812
CD86 CD86 molecule 0.00912263
MT1H metallothionein 1H 0.00899864
DPEP1 dipeptidase 1 (renal) 0.00897812
HMG20B high mobility group 20B 0.00896901
MMP8 matrix metallopeptidase 8 0.00890964
TIMP2 TIMP metallopeptidase inhibitor 2 0.00890334
TGFA transforming growth factor, alpha 0.00881482
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00881438
CRYBG1 crystallin beta-gamma domain containing 1 0.00878795
RAB29 RAB29, member RAS oncogene family 0.00878311
ZBED2 zinc finger, BED-type containing 2 0.00877901
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00877651
ERBB4 erb-b2 receptor tyrosine kinase 4 0.00876646
GRN granulin 0.00872966
MFSD12 major facilitator superfamily domain containing 12 0.00870752
COCH cochlin 0.00867803
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00867418
CTSB cathepsin B 0.00867263
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00866563
STK38 serine/threonine kinase 38 0.00866472
ADD3 adducin 3 (gamma) 0.00866393
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00865365
ERCC5 excision repair cross-complementation group 5 0.00865258
G0S2 G0/G1 switch 2 0.00864648
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00864033
CTSZ cathepsin Z 0.00862899
MKI67 marker of proliferation Ki-67 0.00861421
CHD4 chromodomain helicase DNA binding protein 4 0.00861171
PRUNE2 prune homolog 2 (Drosophila) 0.00856409
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00855292
TTLL7 tubulin tyrosine ligase-like family member 7 0.00854917
CA2 carbonic anhydrase II 0.00852749
EFNB2 ephrin-B2 0.00847792
RGS4 regulator of G-protein signaling 4 0.0084769
CLGN calmegin 0.00843771
TPTE transmembrane phosphatase with tensin homology 0.00840174
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 0.00838702
AHCYL1 adenosylhomocysteinase-like 1 0.00836139
GSDME gasdermin E 0.00835745
NEO1 neogenin 1 0.0083402
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00829531
CD38 CD38 molecule 0.00829103
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00827373
RHOC ras homolog family member C 0.00823262
BCHE butyrylcholinesterase 0.00822338
PRTN3 proteinase 3 0.00822288
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.00821949
SCGB1D2 secretoglobin, family 1D, member 2 0.00816264
TP53I3 tumor protein p53 inducible protein 3 0.0081603
GPR137B G protein-coupled receptor 137B 0.00815443
CANT1 calcium activated nucleotidase 1 0.00813934
NCF1C neutrophil cytosolic factor 1C pseudogene 0.00813635
HBEGF heparin-binding EGF-like growth factor 0.00812582
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00812145
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00811505
MAGEA3 melanoma antigen family A3 0.00807496
GADD45A growth arrest and DNA-damage-inducible, alpha 0.0080652
CDC25B cell division cycle 25B 0.00805153
C5AR1 complement component 5a receptor 1 0.00801023
MYO5A myosin VA (heavy chain 12, myoxin) 0.00799739
SIRPA signal-regulatory protein alpha 0.0079686
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0079594
ZMAT3 zinc finger, matrin-type 3 0.00793755
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00792706
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00792559
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.0079102
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00790393
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00789493
SCD5 stearoyl-CoA desaturase 5 0.00788633
ASS1 argininosuccinate synthase 1 0.00787668
PSAP prosaposin 0.00785328
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00781844
PTK2B protein tyrosine kinase 2 beta 0.0078015
EREG epiregulin 0.00779936
WWC1 WW and C2 domain containing 1 0.00775702
KLHL24 kelch-like family member 24 0.00775053
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00774741
CDKN3 cyclin-dependent kinase inhibitor 3 0.00773499
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00772334
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00771522
RRBP1 ribosome binding protein 1 0.00769712
SFRP4 secreted frizzled-related protein 4 0.00766484
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.00765455
POPDC3 popeye domain containing 3 0.00764518
LRRC17 leucine rich repeat containing 17 0.00759204
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00755406
MAGEA1 melanoma antigen family A1 0.00755351
LARP6 La ribonucleoprotein domain family, member 6 0.00753113
BCL3 B-cell CLL/lymphoma 3 0.00752861
S100A6 S100 calcium binding protein A6 0.00751873
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.00751434
KRT5 keratin 5, type II 0.00750656
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00750235
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.00750069
ETHE1 ethylmalonic encephalopathy 1 0.00748839
LGALS4 lectin, galactoside-binding, soluble, 4 0.00746792
PTTG1 pituitary tumor-transforming 1 0.00743709
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00741649
CCL5 chemokine (C-C motif) ligand 5 0.00740817
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.00737657
MARK4 MAP/microtubule affinity-regulating kinase 4 0.00737651
PI3 peptidase inhibitor 3, skin-derived 0.00735815
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00735182
SSH1 slingshot protein phosphatase 1 0.00732493
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00730912
TUBA1A tubulin, alpha 1a 0.0073022
MLPH melanophilin 0.00729794
ECM1 extracellular matrix protein 1 0.00728533
HSPH1 heat shock 105kDa/110kDa protein 1 0.00728355
MINK1 misshapen-like kinase 1 0.00727118
KAZN kazrin, periplakin interacting protein 0.00725066
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.00723803
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00723154
ROPN1B rhophilin associated tail protein 1B 0.00722521
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1 0.00721296
SCGB2A1 secretoglobin, family 2A, member 1 0.00721049

decreased expression

Symbol Name Standardized Value
PLK1 polo-like kinase 1 -0.0313472
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0200913
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -0.0179814
GPC3 glypican 3 -0.0166589
RPA3 replication protein A3, 14kDa -0.0135157
AKAP7 A kinase (PRKA) anchor protein 7 -0.0129309
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.0128257
MAP7 microtubule-associated protein 7 -0.0126698
FRZB frizzled-related protein -0.0125581
KDM5D lysine (K)-specific demethylase 5D -0.0124818
CALR calreticulin -0.0121794
CDCA4 cell division cycle associated 4 -0.0121388
DCK deoxycytidine kinase -0.0117827
LIG1 ligase I, DNA, ATP-dependent -0.0115238
GINS2 GINS complex subunit 2 (Psf2 homolog) -0.0112067
BCLAF1 BCL2-associated transcription factor 1 -0.0111961
MCM6 minichromosome maintenance complex component 6 -0.0109804
CCL19 chemokine (C-C motif) ligand 19 -0.0107724
FASN fatty acid synthase -0.0106452
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0106431
NPTX2 neuronal pentraxin II -0.0105399
ADGRF5 adhesion G protein-coupled receptor F5 -0.0103592
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0103203
PTPRM protein tyrosine phosphatase, receptor type, M -0.0101848
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.0101184
CCNE2 cyclin E2 -0.0100884
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.0100642
NRN1 neuritin 1 -0.0100117
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -0.0099575
MCM2 minichromosome maintenance complex component 2 -0.00986539
LYZ lysozyme -0.00974689
CDC45 cell division cycle 45 -0.00968108
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.00967479
STEAP1 six transmembrane epithelial antigen of the prostate 1 -0.00967255
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00964757
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00963322
GSTT1 glutathione S-transferase theta 1 -0.00961605
SPON1 spondin 1, extracellular matrix protein -0.00960668
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.00955208
BTBD3 BTB (POZ) domain containing 3 -0.00948065
HOPX HOP homeobox -0.00947706
KLHL23 kelch-like family member 23 -0.00946445
ELOVL6 ELOVL fatty acid elongase 6 -0.00941837
CA9 carbonic anhydrase IX -0.00935889
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00934942
OLFM1 olfactomedin 1 -0.00932654
AKR1C2 aldo-keto reductase family 1, member C2 -0.00931483
NXT1 nuclear transport factor 2-like export factor 1 -0.00930197
MCM5 minichromosome maintenance complex component 5 -0.00929575
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.0092745
FBLN1 fibulin 1 -0.00920965
DEK DEK proto-oncogene -0.00920314
ANOS1 anosmin 1 -0.00913723
DCTPP1 dCTP pyrophosphatase 1 -0.00910471
TLCD3A TLC domain containing 3A -0.00909485
SSBP2 single-stranded DNA binding protein 2 -0.00907472
C2CD5 C2 calcium-dependent domain containing 5 -0.00906297
PRIM1 primase, DNA, polypeptide 1 (49kDa) -0.00903538
AKR1C3 aldo-keto reductase family 1, member C3 -0.00903453
SRSF6 serine/arginine-rich splicing factor 6 -0.00903018
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00900997
SRP72 signal recognition particle 72kDa -0.00899625
AMD1 adenosylmethionine decarboxylase 1 -0.00899155
PLN phospholamban -0.00897298
WDR61 WD repeat domain 61 -0.00893071
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00891007
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00888438
MCM3 minichromosome maintenance complex component 3 -0.00881697
SFTPC surfactant protein C -0.00874118
CYB5A cytochrome b5 type A (microsomal) -0.00870538
FST follistatin -0.00870042
TMEM126B transmembrane protein 126B -0.0086816
MDFIC MyoD family inhibitor domain containing -0.00867356
MGP matrix Gla protein -0.00866786
UBE2N ubiquitin-conjugating enzyme E2N -0.00860488
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00856718
CDT1 chromatin licensing and DNA replication factor 1 -0.00856355
PALB2 partner and localizer of BRCA2 -0.00849358
CFH complement factor H -0.00847844
TMEM106C transmembrane protein 106C -0.00847463
FANCG Fanconi anemia, complementation group G -0.00846991
COMP cartilage oligomeric matrix protein -0.00846114
PFKL phosphofructokinase, liver -0.00844235
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.0084417
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.0084218
MB myoglobin -0.00841296
GRB14 growth factor receptor-bound protein 14 -0.00841111
SRSF7 serine/arginine-rich splicing factor 7 -0.00839636
PTGES3 prostaglandin E synthase 3 (cytosolic) -0.00838772
PRDX2 peroxiredoxin 2 -0.00838145
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00836698
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00833184
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.00831937
MIS12 MIS12 kinetochore complex component -0.00831094
GSTA4 glutathione S-transferase alpha 4 -0.00830925
RPIA ribose 5-phosphate isomerase A -0.00830409
ATF1 activating transcription factor 1 -0.0082473
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) -0.00823264
DAPK1 death-associated protein kinase 1 -0.00822465
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -0.00822449
SUB1 SUB1 homolog (S. cerevisiae) -0.00821915
IFRD2 interferon-related developmental regulator 2 -0.00819998
C7 complement component 7 -0.00818601
GCH1 GTP cyclohydrolase 1 -0.00817859
BMPR1A bone morphogenetic protein receptor, type IA -0.00816061
ASB13 ankyrin repeat and SOCS box containing 13 -0.00813765
ITM2A integral membrane protein 2A -0.00812666
BST2 bone marrow stromal cell antigen 2 -0.00811345
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -0.00811232
PMF1 polyamine-modulated factor 1 -0.00809996
SNRK SNF related kinase -0.00809851
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00808089
ACAT2 acetyl-CoA acetyltransferase 2 -0.00807568
MCM9 minichromosome maintenance complex component 9 -0.00805896
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00805814
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -0.00803542
UNG uracil-DNA glycosylase -0.00803084
RGS5 regulator of G-protein signaling 5 -0.00801899
TMPO thymopoietin -0.00800488
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00799688
NREP neuronal regeneration related protein -0.00799493
REEP1 receptor accessory protein 1 -0.00791945
MUC1 mucin 1, cell surface associated -0.00790388
USP1 ubiquitin specific peptidase 1 -0.00789724
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.00788647
VWA1 von Willebrand factor A domain containing 1 -0.00787725
H1-10 H1.10 linker histone -0.00786049
EML4 echinoderm microtubule associated protein like 4 -0.00784624
SUMO3 small ubiquitin-like modifier 3 -0.00783434
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00782413
RNASEH2A ribonuclease H2, subunit A -0.0078125
RNPS1 RNA binding protein S1, serine-rich domain -0.00779361
RBBP4 retinoblastoma binding protein 4 -0.0077852
RPS5 ribosomal protein S5 -0.00778508
CCL21 chemokine (C-C motif) ligand 21 -0.00778065
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.00777686
CAND1 cullin-associated and neddylation-dissociated 1 -0.0077509
MPZL2 myelin protein zero-like 2 -0.00774974
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -0.0077087
CCL2 chemokine (C-C motif) ligand 2 -0.00770537
INSIG1 insulin induced gene 1 -0.0077027
C8ORF4 chromosome 8 open reading frame 4 -0.00768781
MAT2B methionine adenosyltransferase II, beta -0.00765501
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.00765176
NYNRIN NYN domain and retroviral integrase containing -0.00764431
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00760009
C12ORF29 chromosome 12 open reading frame 29 -0.00759453
AKR1C1 aldo-keto reductase family 1, member C1 -0.007586
THAP12 THAP domain containing 12 -0.00758293
COMMD10 COMM domain containing 10 -0.00757371
OXA1L oxidase (cytochrome c) assembly 1-like -0.00755644
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -0.00753003
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00751774
MET MET proto-oncogene, receptor tyrosine kinase -0.00751502
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00751426
PCGF2 polycomb group ring finger 2 -0.00747047
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00738945
SRSF1 serine/arginine-rich splicing factor 1 -0.00735836
KLHDC3 kelch domain containing 3 -0.00735022
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -0.00731905
CPE carboxypeptidase E -0.00731067
FBXO3 F-box protein 3 -0.00730766
TARDBP TAR DNA binding protein -0.00728707
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.00727646
SRM spermidine synthase -0.00726753
TXNDC9 thioredoxin domain containing 9 -0.00726489
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00726367
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) -0.007253
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00724956
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00724702
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -0.00724448
LIMCH1 LIM and calponin homology domains 1 -0.00724124
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00724106
RANBP1 RAN binding protein 1 -0.00721422
RFC2 replication factor C (activator 1) 2, 40kDa -0.00720557
TMEM168 transmembrane protein 168 -0.00719945
SFTPA2 surfactant protein A2 -0.00719744
LCMT2 leucine carboxyl methyltransferase 2 -0.00718876
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00717506
TFRC transferrin receptor -0.00717415
MRPS27 mitochondrial ribosomal protein S27 -0.00717263
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.0071706
CADPS2 Ca++-dependent secretion activator 2 -0.007164
PCNP PEST proteolytic signal containing nuclear protein -0.00715849
CDK1 cyclin-dependent kinase 1 -0.00715517
SEPTIN10 septin 10 -0.007122
ASF1A anti-silencing function 1A histone chaperone -0.00711187
SETMAR SET domain and mariner transposase fusion gene -0.00710419
DPT dermatopontin -0.0070703
METTL9 methyltransferase like 9 -0.0070694
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00703972
THAP7 THAP domain containing 7 -0.00701882
MAOA monoamine oxidase A -0.00700468
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -0.00699284
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.0069921
ASF1B anti-silencing function 1B histone chaperone -0.0069913
SLBP stem-loop binding protein -0.00697726
DCTN5 dynactin 5 (p25) -0.00694071
SMAD4 SMAD family member 4 -0.00693177
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -0.00693089
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -0.00691827
MRPL3 mitochondrial ribosomal protein L3 -0.00691502
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.00691136
BET1 Bet1 golgi vesicular membrane trafficking protein -0.00690899
CPNE3 copine III -0.00690224
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00689842
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00689057
CCNC cyclin C -0.0068873
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00685492
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00685419
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -0.00683159
SDC2 syndecan 2 -0.00681493
IFI44 interferon-induced protein 44 -0.00681002
TMEM106B transmembrane protein 106B -0.00680886
CDK4 cyclin-dependent kinase 4 -0.00680521
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00679601
DICER1 dicer 1, ribonuclease type III -0.00677588
PCIF1 PDX1 C-terminal inhibiting factor 1 -0.00675669
MRPS28 mitochondrial ribosomal protein S28 -0.0067534
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon -0.0067439
EPAS1 endothelial PAS domain protein 1 -0.00673724
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.00673433
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -0.00673362
NRXN1 neurexin 1 -0.00672909
RBMX RNA binding motif protein, X-linked -0.00672463
POU5F1B POU class 5 homeobox 1B -0.00671506
SEH1L SEH1-like (S. cerevisiae) -0.00671086
ADCY3 adenylate cyclase 3 -0.00671065
ESD esterase D -0.00669331
SRSF3 serine/arginine-rich splicing factor 3 -0.00669069
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00668701
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00666614
TLE2 transducin-like enhancer of split 2 -0.00666111
LIN7C lin-7 homolog C (C. elegans) -0.00664917
MLX MLX, MAX dimerization protein -0.00663466
MX2 MX dynamin-like GTPase 2 -0.00662434
CBFB core-binding factor, beta subunit -0.0066241
CHRDL1 chordin-like 1 -0.00661846
TRIM44 tripartite motif containing 44 -0.00660793
RUFY3 RUN and FYVE domain containing 3 -0.00659563
HIRIP3 HIRA interacting protein 3 -0.00658541
HAUS4 HAUS augmin-like complex, subunit 4 -0.00658513
SEPP1 selenoprotein P, plasma, 1 -0.00658341
ALG6 ALG6, alpha-1,3-glucosyltransferase -0.00657916
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -0.00657842
RBM14 RNA binding motif protein 14 -0.00657824
B3GNT1 -0.00656904
EAPP E2F-associated phosphoprotein -0.00656341
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) -0.0065596
WTAP Wilms tumor 1 associated protein -0.00655935