PLK1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description polo-like kinase 1| (NCBI Entrez Gene Database, 5347)
External Link http://www.ncbi.nlm.nih.gov/gene/5347
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Genes

84 substrates of the kinase PLK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
ANAPC1 anaphase promoting complex subunit 1
ANAPC4 anaphase promoting complex subunit 4
ANAPC7 anaphase promoting complex subunit 7
ATXN10 ataxin 10
AXIN1 axin 1
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
BORA bora, aurora kinase A activator
BRCA2 breast cancer 2, early onset
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CCNB1 cyclin B1
CCNT1 cyclin T1
CDC16 cell division cycle 16
CDC23 cell division cycle 23
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC27 cell division cycle 27
CDC6 cell division cycle 6
CENPQ centromere protein Q
CENPU centromere protein U
CEP55 centrosomal protein 55kDa
CHEK2 checkpoint kinase 2
CLIP1 CAP-GLY domain containing linker protein 1
CLSPN claspin
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCTN1 dynactin 1
DVL2 dishevelled segment polarity protein 2
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FADD Fas (TNFRSF6)-associated via death domain
FBXO5 F-box protein 5
GORASP1 golgi reassembly stacking protein 1, 65kDa
GTSE1 G-2 and S-phase expressed 1
HSF1 heat shock transcription factor 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KAT7 K(lysine) acetyltransferase 7
KIF23 kinesin family member 23
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIZ kizuna centrosomal protein
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP9 microtubule-associated protein 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NINL ninein-like
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUDC nudC nuclear distribution protein
OPTN optineurin
ORC2 origin recognition complex, subunit 2
PCNT pericentrin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRC1 protein regulator of cytokinesis 1
PTEN phosphatase and tensin homolog
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RACGAP1 Rac GTPase activating protein 1
RAD51 RAD51 recombinase
RAN RAN, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RIOK2 RIO kinase 2
SGOL1 shugoshin-like 1 (S. pombe)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SRI sorcin
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SVIL supervillin
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TEX14 testis expressed 14
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TRIOBP TRIO and F-actin binding protein
VIM vimentin
WEE1 WEE1 G2 checkpoint kinase
YY1 YY1 transcription factor
ZMYM2 zinc finger, MYM-type 2