PLK2_knockdown_87_GSE27869 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27869
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Genes

600 genes differentially expressed following the PLK2_knockdown_87_GSE27869 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
UPK1A uroplakin 1A 3.75906
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2.81409
RPS3 ribosomal protein S3 2.77909
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 2.66026
XCL1 chemokine (C motif) ligand 1 2.54941
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 2.51251
TMX4 thioredoxin-related transmembrane protein 4 2.50958
HEBP1 heme binding protein 1 2.49767
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.42484
CAB39L calcium binding protein 39-like 2.39937
TSPAN17 tetraspanin 17 2.38211
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 2.36205
MRPL21 mitochondrial ribosomal protein L21 2.32192
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 2.32113
DBT dihydrolipoamide branched chain transacylase E2 2.31061
RPLP2 ribosomal protein, large, P2 2.3106
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 2.30419
KIAA0391 KIAA0391 2.28079
ZRANB2 zinc finger, RAN-binding domain containing 2 2.27451
SRD5A3 steroid 5 alpha-reductase 3 2.24974
LOC81691 exonuclease NEF-sp 2.24697
ALG9 ALG9, alpha-1,2-mannosyltransferase 2.24467
MBIP MAP3K12 binding inhibitory protein 1 2.20187
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 2.19812
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 2.19592
TMEM185B transmembrane protein 185B 2.1847
RWDD1 RWD domain containing 1 2.17714
LSMEM1 leucine-rich single-pass membrane protein 1 2.15985
EEF1B2 eukaryotic translation elongation factor 1 beta 2 2.15145
PRPF18 pre-mRNA processing factor 18 2.14518
TLDC1 TBC/LysM-associated domain containing 1 2.12298
PHIP pleckstrin homology domain interacting protein 2.1223
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) 2.11939
TM2D2 TM2 domain containing 2 2.11857
UBE2J1 ubiquitin-conjugating enzyme E2, J1 2.11414
ZSCAN5A zinc finger and SCAN domain containing 5A 2.10393
PEX5 peroxisomal biogenesis factor 5 2.09825
GTF3A general transcription factor IIIA 2.09421
RMDN3 regulator of microtubule dynamics 3 2.08632
MBD2 methyl-CpG binding domain protein 2 2.08293
LMBRD1 LMBR1 domain containing 1 2.0776
BCORL1 BCL6 corepressor-like 1 2.07638
TM2D3 TM2 domain containing 3 2.07285
KIN Kin17 DNA and RNA binding protein 2.05609
COMMD9 COMM domain containing 9 2.05208
ZNF418 zinc finger protein 418 2.05059
SPICE1 spindle and centriole associated protein 1 2.04037
VAC14 Vac14 homolog (S. cerevisiae) 2.03815
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.03667
ABI2 abl-interactor 2 2.02445
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.02252
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) 2.01644
RNASEH1 ribonuclease H1 2.0113
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.00562
FRMD4A FERM domain containing 4A 2.00273
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.00263
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 1.99995
NFIA nuclear factor I/A 1.9973
IFT46 intraflagellar transport 46 1.9852
NIPAL3 NIPA-like domain containing 3 1.98103
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.9746
MTCH2 mitochondrial carrier 2 1.9617
ZNF304 zinc finger protein 304 1.94844
TTC8 tetratricopeptide repeat domain 8 1.94816
TPST2 tyrosylprotein sulfotransferase 2 1.943
ACBD5 acyl-CoA binding domain containing 5 1.93265
GTF2A1 general transcription factor IIA, 1, 19/37kDa 1.92779
HADH hydroxyacyl-CoA dehydrogenase 1.92744
TMEM147 transmembrane protein 147 1.90515
C18ORF21 chromosome 18 open reading frame 21 1.9035
SAP130 Sin3A-associated protein, 130kDa 1.90064
FRMD5 FERM domain containing 5 1.89954
UBE2K ubiquitin-conjugating enzyme E2K 1.89404
RUVBL1 RuvB-like AAA ATPase 1 1.8899
RPS26 ribosomal protein S26 1.88701
PCYOX1L prenylcysteine oxidase 1 like 1.87772
MYO19 myosin XIX 1.877
TPM1 tropomyosin 1 (alpha) 1.86965
ARMCX3 armadillo repeat containing, X-linked 3 1.86324
CHRND cholinergic receptor, nicotinic, delta (muscle) 1.86313
KDM8 lysine (K)-specific demethylase 8 1.86091
ERO1LB ERO1-like beta (S. cerevisiae) 1.85767
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 1.85748
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta 1.85257
NFYC nuclear transcription factor Y, gamma 1.84958
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.84705
RANBP1 RAN binding protein 1 1.84457
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 1.83591
GGCT gamma-glutamylcyclotransferase 1.83531
BST1 bone marrow stromal cell antigen 1 1.83403
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.83261
TRAPPC13 trafficking protein particle complex 13 1.82578
TMOD4 tropomodulin 4 (muscle) 1.82385
ULK3 unc-51 like kinase 3 1.82141
ZFAND1 zinc finger, AN1-type domain 1 1.81985
GNL1 guanine nucleotide binding protein-like 1 1.81872
SLC26A6 solute carrier family 26 (anion exchanger), member 6 1.81837
THOC5 THO complex 5 1.81266
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.81254
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.81222
BCAS4 breast carcinoma amplified sequence 4 1.81078
N6AMT2 N-6 adenine-specific DNA methyltransferase 2 (putative) 1.8107
ZNF616 zinc finger protein 616 1.80909
RER1 retention in endoplasmic reticulum sorting receptor 1 1.80756
MALSU1 mitochondrial assembly of ribosomal large subunit 1 1.80177
PREP prolyl endopeptidase 1.79853
TSPAN33 tetraspanin 33 1.79486
C5ORF66 chromosome 5 open reading frame 66 1.79371
ARMCX5 armadillo repeat containing, X-linked 5 1.79305
CKS2 CDC28 protein kinase regulatory subunit 2 1.79277
EFNA4 ephrin-A4 1.7921
LRRC46 leucine rich repeat containing 46 1.79067
TMEM245 transmembrane protein 245 1.78833
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 1.78774
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 1.78579
LIN7B lin-7 homolog B (C. elegans) 1.78322
RARB retinoic acid receptor, beta 1.78318
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant 1.78109
OTUD6B-AS1 OTUD6B antisense RNA 1 (head to head) 1.78002
CDK12 cyclin-dependent kinase 12 1.77877
SMG5 SMG5 nonsense mediated mRNA decay factor 1.77777
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 1.77703
MED4 mediator complex subunit 4 1.77696
ICAM1 intercellular adhesion molecule 1 1.77416
DOK4 docking protein 4 1.77331
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 1.77302
TTC26 tetratricopeptide repeat domain 26 1.76738
GTF2H2 general transcription factor IIH, polypeptide 2, 44kDa 1.76435
KATNAL1 katanin p60 subunit A-like 1 1.7631
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.76105
FOXC2 forkhead box C2 1.75906
OFD1 oral-facial-digital syndrome 1 1.75863
CDV3 CDV3 homolog (mouse) 1.75701
GYS2 glycogen synthase 2 (liver) 1.75138
SEPW1 selenoprotein W, 1 1.74334
FAM20B family with sequence similarity 20, member B 1.74242
TGS1 trimethylguanosine synthase 1 1.74068
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 1.7394
CABLES1 Cdk5 and Abl enzyme substrate 1 1.73763
RPS16 ribosomal protein S16 1.73454
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 1.7329
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.73282
FASTKD1 FAST kinase domains 1 1.73167
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.72503
UBL7-AS1 UBL7 antisense RNA 1 (head to head) 1.72315
IFT22 intraflagellar transport 22 1.72296
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 1.72256
SGPL1 sphingosine-1-phosphate lyase 1 1.72096
PLA2G12A phospholipase A2, group XIIA 1.71755
PYCARD PYD and CARD domain containing 1.71697
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 1.71516
RLIM ring finger protein, LIM domain interacting 1.71416
RPP40 ribonuclease P/MRP 40kDa subunit 1.71149
GIN1 gypsy retrotransposon integrase 1 1.71046
RNASE3 ribonuclease, RNase A family, 3 1.7095
GDF9 growth differentiation factor 9 1.70757
RAB2B RAB2B, member RAS oncogene family 1.7065
SMIM7 small integral membrane protein 7 1.70529
GNA12 guanine nucleotide binding protein (G protein) alpha 12 1.70432
PLXNA1 plexin A1 1.70057
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 1.70016
RPS27 ribosomal protein S27 1.70011
CARF calcium responsive transcription factor 1.69523
KIAA0907 KIAA0907 1.69428
CORO1A coronin, actin binding protein, 1A 1.692
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 1.69194
MORC2 MORC family CW-type zinc finger 2 1.6916
PDCD10 programmed cell death 10 1.68808
DNAAF2 dynein, axonemal, assembly factor 2 1.68616
PHF20 PHD finger protein 20 1.68593
SFXN1 sideroflexin 1 1.68448
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.6841
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.68349
RPL39 ribosomal protein L39 1.68008
GPR89B G protein-coupled receptor 89B 1.67812
SENP5 SUMO1/sentrin specific peptidase 5 1.67733
CYR61 cysteine-rich, angiogenic inducer, 61 1.67117
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 1.67061
MNS1 meiosis-specific nuclear structural 1 1.66596
COL3A1 collagen, type III, alpha 1 1.66584
TRIM36 tripartite motif containing 36 1.66436
MAST3 microtubule associated serine/threonine kinase 3 1.6636
ZNF768 zinc finger protein 768 1.66244
SSBP4 single stranded DNA binding protein 4 1.66074
LINC00476 long intergenic non-protein coding RNA 476 1.65972
BAIAP2L1 BAI1-associated protein 2-like 1 1.65712
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.65288
INIP INTS3 and NABP interacting protein 1.65153
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 1.64884
HINT3 histidine triad nucleotide binding protein 3 1.64757
ZNF225 zinc finger protein 225 1.64446
MID2 midline 2 1.64413
HYI hydroxypyruvate isomerase (putative) 1.64361
PRNP prion protein 1.64206
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 1.63996
HTRA1 HtrA serine peptidase 1 1.63883
ZNF697 zinc finger protein 697 1.63802
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 1.63733
TIPRL TOR signaling pathway regulator 1.63732
TAPT1 transmembrane anterior posterior transformation 1 1.63476
CCT7 chaperonin containing TCP1, subunit 7 (eta) 1.63461
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.63331
TBCB tubulin folding cofactor B 1.63305
EIF1B eukaryotic translation initiation factor 1B 1.62782
FAM193A family with sequence similarity 193, member A 1.62628
OSCP1 organic solute carrier partner 1 1.62542
NUTF2 nuclear transport factor 2 1.62328
LAD1 ladinin 1 1.62313
CMC2 C-x(9)-C motif containing 2 1.62091
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 1.61752
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 1.6162
H2AFY H2A histone family, member Y 1.61578
COASY CoA synthase 1.61442
GPR107 G protein-coupled receptor 107 1.61392
SETMAR SET domain and mariner transposase fusion gene 1.60698
PARVA parvin, alpha 1.60654
FANCF Fanconi anemia, complementation group F 1.60614
MTFMT mitochondrial methionyl-tRNA formyltransferase 1.60383
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 1.6028
PPP1R18 protein phosphatase 1, regulatory subunit 18 1.60275
EMC4 ER membrane protein complex subunit 4 1.60238
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 1.59834
FGGY FGGY carbohydrate kinase domain containing 1.59641
COMMD1 copper metabolism (Murr1) domain containing 1 1.59626
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 1.59566
HSF2 heat shock transcription factor 2 1.59555
KLK12 kallikrein-related peptidase 12 1.59517
ASB3 ankyrin repeat and SOCS box containing 3 1.59462
MKRN1 makorin ring finger protein 1 1.59301
IGFLR1 IGF-like family receptor 1 1.5929
CNFN cornifelin 1.59275
RUFY1 RUN and FYVE domain containing 1 1.59241
CEPT1 choline/ethanolamine phosphotransferase 1 1.59191
PRPF39 pre-mRNA processing factor 39 1.59136
TDP2 tyrosyl-DNA phosphodiesterase 2 1.5913
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 1.58972
ARL4D ADP-ribosylation factor-like 4D 1.58809
STRBP spermatid perinuclear RNA binding protein 1.58705
MRPS23 mitochondrial ribosomal protein S23 1.58697
REC8 REC8 meiotic recombination protein 1.58473
IER3 immediate early response 3 1.58407
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 1.5826
RUNDC1 RUN domain containing 1 1.58075
TRIM33 tripartite motif containing 33 1.58004
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 1.57981
MRPS15 mitochondrial ribosomal protein S15 1.57914
PEX3 peroxisomal biogenesis factor 3 1.57904
NOTCH2 notch 2 1.57804
VN1R4 vomeronasal 1 receptor 4 1.57799
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 1.57612
ACVR1B activin A receptor, type IB 1.57415
COX7C cytochrome c oxidase subunit VIIc 1.57216
NCOA1 nuclear receptor coactivator 1 1.57083
HIST1H2BF histone cluster 1, H2bf 1.56725
LOC158402 uncharacterized LOC158402 1.56433
PTBP2 polypyrimidine tract binding protein 2 1.56399
TCEAL3 transcription elongation factor A (SII)-like 3 1.56301
RAD54L RAD54-like (S. cerevisiae) 1.56261
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae) 1.56138
HDAC4 histone deacetylase 4 1.56123
CRYBB3 crystallin, beta B3 1.56058
UBASH3B ubiquitin associated and SH3 domain containing B 1.55847
TXNDC11 thioredoxin domain containing 11 1.55845
KLHL36 kelch-like family member 36 1.55669
MARC1 mitochondrial amidoxime reducing component 1 1.55539
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 1.55523
C2ORF47 chromosome 2 open reading frame 47 1.55417
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) 1.55319
WAC WW domain containing adaptor with coiled-coil 1.54843
FAM8A1 family with sequence similarity 8, member A1 1.54769
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 1.54763
PRMT1 protein arginine methyltransferase 1 1.54745
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 1.5468
HN1 hematological and neurological expressed 1 1.54499
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 1.54484
FAIM Fas apoptotic inhibitory molecule 1.54376
FBL fibrillarin 1.54319
DSCC1 DNA replication and sister chromatid cohesion 1 1.5428
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 1.54142
AZIN2 antizyme inhibitor 2 1.53883
ATG14 autophagy related 14 1.53638
CUTA cutA divalent cation tolerance homolog (E. coli) 1.53355
GALK2 galactokinase 2 1.53306
ELOVL6 ELOVL fatty acid elongase 6 1.53278
FHOD1 formin homology 2 domain containing 1 1.53122
NCOA3 nuclear receptor coactivator 3 1.53037
SLC25A42 solute carrier family 25, member 42 1.53003
FAM188A family with sequence similarity 188, member A 1.52891
CFL2 cofilin 2 (muscle) 1.52879
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 1.52828
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.52784
C1ORF50 chromosome 1 open reading frame 50 1.52769
PLAUR plasminogen activator, urokinase receptor 1.52697
STX1A syntaxin 1A (brain) 1.5251
FLNC filamin C, gamma 1.52503
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 1.52465
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 1.52374
KIF1C kinesin family member 1C 1.52345
FGF23 fibroblast growth factor 23 1.52268
EIF4H eukaryotic translation initiation factor 4H 1.52161

decreased expression

Symbol Name Standardized Value
COX7B cytochrome c oxidase subunit VIIb -3.64787
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -3.43403
FAM96A family with sequence similarity 96, member A -3.41129
TMEM258 transmembrane protein 258 -3.36422
PARL presenilin associated, rhomboid-like -3.18374
ANXA2 annexin A2 -3.09951
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -3.08075
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -3.08058
EFHD2 EF-hand domain family, member D2 -2.98108
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.96893
GLOD4 glyoxalase domain containing 4 -2.96745
RITA1 RBPJ interacting and tubulin associated 1 -2.93286
MRPL34 mitochondrial ribosomal protein L34 -2.913
SAMM50 SAMM50 sorting and assembly machinery component -2.90284
DET1 de-etiolated homolog 1 (Arabidopsis) -2.90102
ARV1 ARV1 homolog (S. cerevisiae) -2.84889
KCTD10 potassium channel tetramerization domain containing 10 -2.80851
HPRT1 hypoxanthine phosphoribosyltransferase 1 -2.80268
RPL41 ribosomal protein L41 -2.79564
COPS8 COP9 signalosome subunit 8 -2.78948
GSTZ1 glutathione S-transferase zeta 1 -2.77125
SEC62 SEC62 homolog (S. cerevisiae) -2.76291
ZNF26 zinc finger protein 26 -2.74954
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 -2.69212
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.66201
RPL19 ribosomal protein L19 -2.64118
FAM103A1 family with sequence similarity 103, member A1 -2.64051
PNMA1 paraneoplastic Ma antigen 1 -2.63927
MFN2 mitofusin 2 -2.63089
COPA coatomer protein complex, subunit alpha -2.59375
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -2.58403
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.58345
OSGIN2 oxidative stress induced growth inhibitor family member 2 -2.57903
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.57136
MLYCD malonyl-CoA decarboxylase -2.56648
FBXL12 F-box and leucine-rich repeat protein 12 -2.56392
RHBDD1 rhomboid domain containing 1 -2.53118
CYB561 cytochrome b561 -2.50599
RAB8B RAB8B, member RAS oncogene family -2.4672
UVRAG UV radiation resistance associated -2.41878
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.40778
SNRPA1 small nuclear ribonucleoprotein polypeptide A' -2.40609
METTL8 methyltransferase like 8 -2.39802
PUF60 poly-U binding splicing factor 60KDa -2.39633
CCPG1 cell cycle progression 1 -2.38751
PLS3 plastin 3 -2.38479
CTSC cathepsin C -2.33817
ERCC8 excision repair cross-complementation group 8 -2.33683
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -2.33331
KCTD20 potassium channel tetramerization domain containing 20 -2.32527
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.30009
CAB39 calcium binding protein 39 -2.29871
ERCC6L2 excision repair cross-complementation group 6-like 2 -2.27984
CHKA choline kinase alpha -2.27029
MCM2 minichromosome maintenance complex component 2 -2.25169
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.24447
ERICH1 glutamate-rich 1 -2.24389
FEM1B fem-1 homolog b (C. elegans) -2.24288
TUBGCP4 tubulin, gamma complex associated protein 4 -2.23052
CHSY1 chondroitin sulfate synthase 1 -2.22554
ZFHX3 zinc finger homeobox 3 -2.22326
EIF3D eukaryotic translation initiation factor 3, subunit D -2.21466
MED17 mediator complex subunit 17 -2.20907
GPANK1 G patch domain and ankyrin repeats 1 -2.20855
C6ORF203 chromosome 6 open reading frame 203 -2.20288
THAP7 THAP domain containing 7 -2.20179
STK25 serine/threonine kinase 25 -2.19482
RGS3 regulator of G-protein signaling 3 -2.18551
WDYHV1 WDYHV motif containing 1 -2.17192
CBX3 chromobox homolog 3 -2.17143
FAM118B family with sequence similarity 118, member B -2.16944
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -2.15377
SETD8 SET domain containing (lysine methyltransferase) 8 -2.15302
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.1528
RACGAP1 Rac GTPase activating protein 1 -2.14933
ARL13B ADP-ribosylation factor-like 13B -2.13349
CTSL cathepsin L -2.13131
FAM195B family with sequence similarity 195, member B -2.13029
MRGBP MRG/MORF4L binding protein -2.12844
SORD sorbitol dehydrogenase -2.12548
IL10RB-AS1 IL10RB antisense RNA 1 (head to head) -2.1196
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.11537
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.10837
MEPCE methylphosphate capping enzyme -2.10482
CD63 CD63 molecule -2.10321
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -2.10301
NCOR1 nuclear receptor corepressor 1 -2.10173
TMEM216 transmembrane protein 216 -2.10097
RNMT RNA (guanine-7-) methyltransferase -2.08906
GEMIN2 gem (nuclear organelle) associated protein 2 -2.08751
SCCPDH saccharopine dehydrogenase (putative) -2.07935
BRAP BRCA1 associated protein -2.0787
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.07062
DTWD1 DTW domain containing 1 -2.06698
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -2.06243
CMA1 chymase 1, mast cell -2.05901
FBXW11 F-box and WD repeat domain containing 11 -2.05849
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -2.04992
TRAPPC2 trafficking protein particle complex 2 -2.04812
CHERP calcium homeostasis endoplasmic reticulum protein -2.04404
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa -2.04235
KLHL6 kelch-like family member 6 -2.03224
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -2.0314
CCNY cyclin Y -2.03021
TBP TATA box binding protein -2.02966
JAK2 Janus kinase 2 -2.02904
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) -2.02716
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.02649
CREG1 cellular repressor of E1A-stimulated genes 1 -2.0244
COCH cochlin -2.01572
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 -2.01013
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) -2.00966
ANKRD13A ankyrin repeat domain 13A -2.00799
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -2.00688
DNASE1L2 deoxyribonuclease I-like 2 -2.00546
GIMAP4 GTPase, IMAP family member 4 -1.99582
LIMS1 LIM and senescent cell antigen-like domains 1 -1.99425
SDF4 stromal cell derived factor 4 -1.99385
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -1.99349
TPRG1L tumor protein p63 regulated 1-like -1.99063
TBC1D20 TBC1 domain family, member 20 -1.98236
TXNRD1 thioredoxin reductase 1 -1.97669
CCDC126 coiled-coil domain containing 126 -1.97622
TNPO3 transportin 3 -1.97604
PNLIPRP2 pancreatic lipase-related protein 2 -1.97517
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -1.97463
JAGN1 jagunal homolog 1 (Drosophila) -1.97303
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -1.9685
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -1.96278
ZC3H7B zinc finger CCCH-type containing 7B -1.96026
RIMKLB ribosomal modification protein rimK-like family member B -1.95819
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 -1.95418
PLSCR1 phospholipid scramblase 1 -1.9492
AGK acylglycerol kinase -1.94808
ANAPC10 anaphase promoting complex subunit 10 -1.94035
CD99 CD99 molecule -1.93846
TMEM5 transmembrane protein 5 -1.93338
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -1.9324
HAGH hydroxyacylglutathione hydrolase -1.93113
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -1.92362
FBXO10 F-box protein 10 -1.91943
ABHD14A abhydrolase domain containing 14A -1.91914
FXN frataxin -1.91773
TTC31 tetratricopeptide repeat domain 31 -1.90656
RPL10A ribosomal protein L10a -1.906
AKT2 v-akt murine thymoma viral oncogene homolog 2 -1.90569
PCBP1 poly(rC) binding protein 1 -1.90384
GLRB glycine receptor, beta -1.9007
PCIF1 PDX1 C-terminal inhibiting factor 1 -1.89601
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -1.89463
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -1.89368
ITGB1BP1 integrin beta 1 binding protein 1 -1.89052
PHKA1 phosphorylase kinase, alpha 1 (muscle) -1.88751
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -1.88517
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) -1.88323
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.88153
LIFR leukemia inhibitory factor receptor alpha -1.88093
IGF1R insulin-like growth factor 1 receptor -1.8788
ZXDB zinc finger, X-linked, duplicated B -1.87787
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 -1.87476
C9ORF156 chromosome 9 open reading frame 156 -1.87333
CFAP20 cilia and flagella associated protein 20 -1.87065
GSTM3 glutathione S-transferase mu 3 (brain) -1.86625
INTS7 integrator complex subunit 7 -1.86261
FKBP1A FK506 binding protein 1A, 12kDa -1.86211
DGCR2 DiGeorge syndrome critical region gene 2 -1.85963
YAP1 Yes-associated protein 1 -1.85865
SCO2 SCO2 cytochrome c oxidase assembly protein -1.85708
CCDC130 coiled-coil domain containing 130 -1.85175
OSER1 oxidative stress responsive serine-rich 1 -1.84972
RAB6B RAB6B, member RAS oncogene family -1.84496
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 -1.8431
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 -1.83892
PCCB propionyl CoA carboxylase, beta polypeptide -1.83842
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.83831
SUMO1 small ubiquitin-like modifier 1 -1.83245
ARHGAP31 Rho GTPase activating protein 31 -1.83016
FBXL2 F-box and leucine-rich repeat protein 2 -1.82818
TEX2 testis expressed 2 -1.82625
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -1.82464
RUFY2 RUN and FYVE domain containing 2 -1.82349
MORC4 MORC family CW-type zinc finger 4 -1.82278
SGSH N-sulfoglucosamine sulfohydrolase -1.82259
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -1.81817
ANAPC13 anaphase promoting complex subunit 13 -1.81519
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.81495
ZNF80 zinc finger protein 80 -1.81486
ZNF641 zinc finger protein 641 -1.80717
ELAVL3 ELAV like neuron-specific RNA binding protein 3 -1.8037
CSNK1E casein kinase 1, epsilon -1.80054
NDFIP2 Nedd4 family interacting protein 2 -1.79291
PHF5A PHD finger protein 5A -1.79086
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -1.78888
STX4 syntaxin 4 -1.78657
STAT5B signal transducer and activator of transcription 5B -1.78599
FAM107A family with sequence similarity 107, member A -1.78042
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -1.77773
LUM lumican -1.77424
UBE4A ubiquitination factor E4A -1.77359
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -1.77286
FN3KRP fructosamine 3 kinase related protein -1.76816
LEMD2 LEM domain containing 2 -1.76814
TACC1 transforming, acidic coiled-coil containing protein 1 -1.76801
SSR1 signal sequence receptor, alpha -1.76526
PTPRD protein tyrosine phosphatase, receptor type, D -1.76275
ANKRD55 ankyrin repeat domain 55 -1.76197
PPP2R5B protein phosphatase 2, regulatory subunit B', beta -1.75938
SRGN serglycin -1.75511
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -1.75399
ZNF783 zinc finger family member 783 -1.75328
NARF nuclear prelamin A recognition factor -1.74998
ZEB1-AS1 ZEB1 antisense RNA 1 -1.7483
ANXA3 annexin A3 -1.74289
AKR1C3 aldo-keto reductase family 1, member C3 -1.73797
YIPF3 Yip1 domain family, member 3 -1.7374
DEFA4 defensin, alpha 4, corticostatin -1.73432
ZBTB34 zinc finger and BTB domain containing 34 -1.73359
TMEM55A transmembrane protein 55A -1.73022
ERI3 ERI1 exoribonuclease family member 3 -1.72963
SAP30BP SAP30 binding protein -1.72923
BCAS2 breast carcinoma amplified sequence 2 -1.72814
ZNF300 zinc finger protein 300 -1.72291
ENDOD1 endonuclease domain containing 1 -1.72285
DHRS13 dehydrogenase/reductase (SDR family) member 13 -1.72071
ESAM endothelial cell adhesion molecule -1.72048
NREP neuronal regeneration related protein -1.72034
NOTCH1 notch 1 -1.71912
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -1.71041
C9ORF3 chromosome 9 open reading frame 3 -1.70754
ZNF512 zinc finger protein 512 -1.69915
RASD2 RASD family, member 2 -1.69863
HMGA2 high mobility group AT-hook 2 -1.69778
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 -1.69535
PPP1R35 protein phosphatase 1, regulatory subunit 35 -1.69162
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -1.69087
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -1.68936
LOC257152 uncharacterized LOC257152 -1.6875
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -1.6848
USP48 ubiquitin specific peptidase 48 -1.6798
PSPC1 paraspeckle component 1 -1.67923
QKI QKI, KH domain containing, RNA binding -1.67656
TBC1D5 TBC1 domain family, member 5 -1.67641
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -1.6756
ZNF71 zinc finger protein 71 -1.67448
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -1.67243
DNHD1 dynein heavy chain domain 1 -1.67099
RPS14 ribosomal protein S14 -1.67015
DLL3 delta-like 3 (Drosophila) -1.6695
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 -1.66685
DAD1 defender against cell death 1 -1.66194
PYGL phosphorylase, glycogen, liver -1.66043
POU2F3 POU class 2 homeobox 3 -1.6578
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -1.65715
FAM120C family with sequence similarity 120C -1.65496
MICU2 mitochondrial calcium uptake 2 -1.652
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 -1.65175
TUFT1 tuftelin 1 -1.65145
NAE1 NEDD8 activating enzyme E1 subunit 1 -1.64865
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -1.64831
RABGAP1 RAB GTPase activating protein 1 -1.64778
C10ORF2 chromosome 10 open reading frame 2 -1.64759
GCDH glutaryl-CoA dehydrogenase -1.64628
YPEL5 yippee-like 5 (Drosophila) -1.6443
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 -1.64361
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.64255
GBAS glioblastoma amplified sequence -1.64122
S100A16 S100 calcium binding protein A16 -1.64099
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.64054
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -1.64051
FAM135A family with sequence similarity 135, member A -1.63952
NFE2L2 nuclear factor, erythroid 2-like 2 -1.63564
BFAR bifunctional apoptosis regulator -1.63546
DBN1 drebrin 1 -1.63473
C1ORF123 chromosome 1 open reading frame 123 -1.63399
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -1.63332
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -1.6311
LMO2 LIM domain only 2 (rhombotin-like 1) -1.63012
HBA1 hemoglobin, alpha 1 -1.62919
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.62855
UBTF upstream binding transcription factor, RNA polymerase I -1.62489
MOSPD3 motile sperm domain containing 3 -1.62449
DES desmin -1.623
PELO pelota homolog (Drosophila) -1.62298
FBXL14 F-box and leucine-rich repeat protein 14 -1.62104
TMEM19 transmembrane protein 19 -1.62065
FCRL4 Fc receptor-like 4 -1.61964
DYNLT1 dynein, light chain, Tctex-type 1 -1.61946
C21ORF33 chromosome 21 open reading frame 33 -1.61634
BATF3 basic leucine zipper transcription factor, ATF-like 3 -1.61489
INADL InaD-like (Drosophila) -1.6146
COMMD5 COMM domain containing 5 -1.61346
PTGR1 prostaglandin reductase 1 -1.61275
STARD4 StAR-related lipid transfer (START) domain containing 4 -1.61121
PLK2 polo-like kinase 2 -1.60997
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative) -1.60947
NUDC nudC nuclear distribution protein -1.60935
SDC4 syndecan 4 -1.6093
FAM104B family with sequence similarity 104, member B -1.60879
IRF2BPL interferon regulatory factor 2 binding protein-like -1.60837
BAALC brain and acute leukemia, cytoplasmic -1.60643