PLK4 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description polo-like kinase 4|This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 10733)
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4 substrates of the kinase PLK4 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
CENPJ centromere protein J
FBXW5 F-box and WD repeat domain containing 5
HAND1 heart and neural crest derivatives expressed 1
PLK4 polo-like kinase 4