PLP1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description proteolipid protein 1|This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015] (NCBI Entrez Gene Database, 5354)
External Link http://www.ncbi.nlm.nih.gov/gene/5354
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Genes

71 interacting proteins for PLP1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTB actin, beta
ALDOC aldolase C, fructose-bisphosphate
ARF1 ADP-ribosylation factor 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BASP1 brain abundant, membrane attached signal protein 1
CA4 carbonic anhydrase IV
CALR calreticulin
CANX calnexin
CD59 CD59 molecule, complement regulatory protein
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLTC clathrin, heavy chain (Hc)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNTN1 contactin 1
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX6C cytochrome c oxidase subunit VIc
CYC1 cytochrome c-1
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DPYSL2 dihydropyrimidinase-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FBN2 fibrillin 2
GFAP glial fibrillary acidic protein
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GPM6A glycoprotein M6A
HTT huntingtin
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LRRK2 leucine-rich repeat kinase 2
MAG myelin associated glycoprotein
MBP myelin basic protein
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
NEGR1 neuronal growth regulator 1
NPTN neuroplastin
NTM neurotrimin
OPCML opioid binding protein/cell adhesion molecule-like
PRNP prion protein
PTPRN protein tyrosine phosphatase, receptor type, N
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
SEPT7 septin 7
SIRPA signal-regulatory protein alpha
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SNAP25 synaptosomal-associated protein, 25kDa
STX1A syntaxin 1A (brain)
STX1B syntaxin 1B
STXBP1 syntaxin binding protein 1
SYP synaptophysin
SYT2 synaptotagmin II
THY1 Thy-1 cell surface antigen
TPP1 tripeptidyl peptidase I
TUBB tubulin, beta class I
UQCRC1 ubiquinol-cytochrome c reductase core protein I
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRH ubiquinol-cytochrome c reductase hinge protein
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma