PLX-4720 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

19 kinases inhibited by the PLX-4720 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.36211
PTK6 protein tyrosine kinase 6 1.32726
DDR1 discoidin domain receptor tyrosine kinase 1 1.23916
BLK BLK proto-oncogene, Src family tyrosine kinase 1.2317
CSF1R colony stimulating factor 1 receptor 1.19568
CDK8 cyclin-dependent kinase 8 1.19568
SIK1 salt-inducible kinase 1 1.16838
CSK c-src tyrosine kinase 1.16177
RIOK2 RIO kinase 2 1.1424
LCK LCK proto-oncogene, Src family tyrosine kinase 1.12988
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.11767
EPHB6 EPH receptor B6 1.10576
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.984392
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.959553
TNK2 tyrosine kinase, non-receptor, 2 0.902136
RIPK2 receptor-interacting serine-threonine kinase 2 0.898929
FGR FGR proto-oncogene, Src family tyrosine kinase 0.895762
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.871827
CLK2 CDC-like kinase 2 0.850157