PLX4032 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

27 kinases inhibited by the PLX4032 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 1.36211
DDR1 discoidin domain receptor tyrosine kinase 1 1.34449
MYLK4 myosin light chain kinase family, member 4 1.32726
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.3104
PTK6 protein tyrosine kinase 6 1.30212
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.28583
SLK STE20-like kinase 1.25436
LCK LCK proto-oncogene, Src family tyrosine kinase 1.23916
STK3 serine/threonine kinase 3 1.21703
BLK BLK proto-oncogene, Src family tyrosine kinase 1.19568
FLT3 fms-related tyrosine kinase 3 1.18186
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.17508
SIK1 salt-inducible kinase 1 1.15523
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.11767
RIPK2 receptor-interacting serine-threonine kinase 2 1.06639
STK36 serine/threonine kinase 36 1.05057
CDK8 cyclin-dependent kinase 8 1.05057
EPHB6 EPH receptor B6 0.993117
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.967615
TNK2 tyrosine kinase, non-receptor, 2 0.947851
CSK c-src tyrosine kinase 0.929345
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.929345
CSF1R colony stimulating factor 1 receptor 0.908676
AXL AXL receptor tyrosine kinase 0.895762
FYN FYN proto-oncogene, Src family tyrosine kinase 0.874689
HUNK hormonally up-regulated Neu-associated kinase 0.874689
FGR FGR proto-oncogene, Src family tyrosine kinase 0.871827