PLXNA1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description plexin A1| (NCBI Entrez Gene Database, 5361)
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Genes

340 genes differentially expressed following the PLXNA1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GPR149 G protein-coupled receptor 149 3.49968
COL9A2 collagen, type IX, alpha 2 3.49968
PITX3 paired-like homeodomain 3 3.49968
SCIN scinderin 3.49968
SFRP4 secreted frizzled-related protein 4 3.49968
IMPG1 interphotoreceptor matrix proteoglycan 1 3.49968
DOK2 docking protein 2, 56kDa 3.43491
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 3.43491
MYADML2 myeloid-associated differentiation marker-like 2 3.43491
HPD 4-hydroxyphenylpyruvate dioxygenase 3.43491
IL21R interleukin 21 receptor 3.43491
KLHL34 kelch-like family member 34 3.43491
GPR12 G protein-coupled receptor 12 3.43491
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.43491
KCNK15 potassium channel, two pore domain subfamily K, member 15 3.43491
NANOS3 nanos homolog 3 (Drosophila) 3.41489
NANOS2 nanos homolog 2 (Drosophila) 3.41489
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 3.41489
SSTR1 somatostatin receptor 1 3.41489
APOA2 apolipoprotein A-II 3.41489
SKOR2 SKI family transcriptional corepressor 2 3.41489
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.41489
TMPRSS11A transmembrane protease, serine 11A 3.41489
HLF hepatic leukemia factor 3.41489
FOLR1 folate receptor 1 (adult) 3.41489
INHBB inhibin, beta B 3.41489
ALB albumin 3.41489
ALK anaplastic lymphoma receptor tyrosine kinase 3.41489
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.41489
ZNF503 zinc finger protein 503 3.41489
FOLR2 folate receptor 2 (fetal) 3.41489
PBOV1 prostate and breast cancer overexpressed 1 3.41489
CFAP54 cilia and flagella associated 54 3.41489
OC90 otoconin 90 3.41489
HBZ hemoglobin, zeta 3.41489
CRYGB crystallin, gamma B 3.41489
PTK6 protein tyrosine kinase 6 3.41489
BFSP2 beaded filament structural protein 2, phakinin 3.41489
MYO1G myosin IG 3.41489
MYL7 myosin, light chain 7, regulatory 3.41489
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 3.41489
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 3.41489
NRROS negative regulator of reactive oxygen species 3.41489
FLI1 Fli-1 proto-oncogene, ETS transcription factor 3.41489
TAL2 T-cell acute lymphocytic leukemia 2 3.41489
SLC23A3 solute carrier family 23, member 3 3.41489
OR52E8 olfactory receptor, family 52, subfamily E, member 8 3.41489
LYZL6 lysozyme-like 6 3.41489
GFI1 growth factor independent 1 transcription repressor 3.41489
ADGB androglobin 3.41489
BIRC3 baculoviral IAP repeat containing 3 3.41489
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.41489
GJA5 gap junction protein, alpha 5, 40kDa 3.41489
OR56B2 olfactory receptor family 56 subfamily B member 2 3.41489
DNAAF1 dynein, axonemal, assembly factor 1 3.41489
KRT80 keratin 80, type II 3.41489
ASB4 ankyrin repeat and SOCS box containing 4 3.41489
WNT16 wingless-type MMTV integration site family, member 16 3.41489
SMTNL1 smoothelin-like 1 3.41489
CNTN6 contactin 6 3.41489
MOV10L1 Mov10 RISC complex RNA helicase like 1 3.41489
PGA5 pepsinogen 5, group I (pepsinogen A) 3.41489
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.41489
ZNF726 zinc finger protein 726 3.41489
CES4A carboxylesterase 4A 3.41489
EXOC1L exocyst complex component 1 like 3.41489
EZHIP EZH inhibitory protein 3.41489
JAML junction adhesion molecule like 3.41489
GK3 glycerol kinase 3 3.41489
ANGPTL8 angiopoietin like 8 3.41489
VSIR V-set immunoregulatory receptor 3.41489
H2BC1 H2B clustered histone 1 3.41489
NECTIN4 nectin cell adhesion molecule 4 3.41489
NLK nemo-like kinase 3.41489
SAA4 serum amyloid A4, constitutive 3.41489
CPED1 cadherin-like and PC-esterase domain containing 1 3.41489
FAM3D family with sequence similarity 3, member D 3.41489
ZNF98 zinc finger protein 98 3.41489
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.41489
SYCP2 synaptonemal complex protein 2 3.41489
PCDHA8 protocadherin alpha 8 3.41489
PDILT protein disulfide isomerase-like, testis expressed 3.41489
HNF4A hepatocyte nuclear factor 4, alpha 3.41489
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.41489
ATP13A4 ATPase type 13A4 3.41489
TM6SF1 transmembrane 6 superfamily member 1 3.41489
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 3.41489
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 3.41489
ZAN zonadhesin (gene/pseudogene) 3.41489
AWAT1 acyl-CoA wax alcohol acyltransferase 1 3.41489
DMBX1 diencephalon/mesencephalon homeobox 1 3.41489
DAO D-amino-acid oxidase 3.41489
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 3.41489
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 3.41489
GJA9 gap junction protein, alpha 9, 59kDa 3.41489
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.41489
LCN2 lipocalin 2 3.41489
FAM177B family with sequence similarity 177, member B 3.41489
CD244 CD244 molecule, natural killer cell receptor 2B4 3.41489
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.41489
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 3.41489
TRIM50 tripartite motif containing 50 3.41489
PCDHGA7 protocadherin gamma subfamily A, 7 3.41489
FOXE1 forkhead box E1 3.41489
CDHR4 cadherin-related family member 4 3.41489
NOX1 NADPH oxidase 1 3.41489
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 3.41489
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 3.41489
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.41489
NPPA natriuretic peptide A 3.41489
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 3.41489
EDN1 endothelin 1 3.41489
CST9 cystatin 9 (testatin) 3.41489
CLRN1 clarin 1 3.41489
EVPLL envoplakin-like 3.41489
TEKT1 tektin 1 3.41489
TEX19 testis expressed 19 3.41489
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.41489
CPN2 carboxypeptidase N, polypeptide 2 3.41489
WNT10B wingless-type MMTV integration site family, member 10B 3.41489
MEPE matrix extracellular phosphoglycoprotein 3.41489
PLA2G5 phospholipase A2, group V 3.41489
ZNF831 zinc finger protein 831 3.41489
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.41489
OR52N2 olfactory receptor, family 52, subfamily N, member 2 3.41489
NKX6-1 NK6 homeobox 1 3.41489
LGALS13 lectin, galactoside-binding, soluble, 13 3.41489
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 3.41489
PCDHA13 protocadherin alpha 13 3.41489
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 3.41489
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.41489
ZNF750 zinc finger protein 750 3.41489
PRSS38 protease, serine, 38 3.41489
INSM1 insulinoma-associated 1 3.41489
LRRC25 leucine rich repeat containing 25 3.41489
PHACTR3 phosphatase and actin regulator 3 3.41489
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 3.41489
ADGRF5 adhesion G protein-coupled receptor F5 3.41489
ROM1 retinal outer segment membrane protein 1 3.41489
CLCA1 chloride channel accessory 1 3.41489
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3.41489
ITPKA inositol-trisphosphate 3-kinase A 3.41489
FOXP3 forkhead box P3 3.41489
ST18 suppression of tumorigenicity 18, zinc finger 3.41489
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.41489
ADRA1B adrenoceptor alpha 1B 3.41489
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.41489
HEPN1 hepatocellular carcinoma, down-regulated 1 3.41489
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.41489
C5ORF46 chromosome 5 open reading frame 46 3.41489
SLC7A4 solute carrier family 7, member 4 3.41489
TSPAN32 tetraspanin 32 3.41489
FAM25A family with sequence similarity 25, member A 3.41489
PLGLB2 plasminogen-like B2 3.41489
MAGEB17 melanoma antigen family B17 3.41489
TMIGD3 transmembrane and immunoglobulin domain containing 3 3.41489
ZMYND10 zinc finger, MYND-type containing 10 3.41489
PLGLB1 plasminogen-like B1 3.41489
ZNF322 zinc finger protein 322 3.36342
TMEM278 transmembrane protein 278 3.24483
HLTF helicase-like transcription factor 3.20791
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 3.13997
FKBPL FK506 binding protein like 3.13887
SRSF12 serine/arginine-rich splicing factor 12 2.89026
CETN2 centrin, EF-hand protein, 2 2.86703
POLR1E polymerase (RNA) I polypeptide E, 53kDa 2.77455
RNF212B ring finger protein 212B 2.75611
SLC30A6 solute carrier family 30 (zinc transporter), member 6 2.72595
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.64896
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.64896
TOP3B topoisomerase (DNA) III beta 2.63082
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.57389
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.56267
CDCA3 cell division cycle associated 3 2.53895
MGLL monoglyceride lipase 2.50063
TRUB1 TruB pseudouridine (psi) synthase family member 1 2.40702
FASTK Fas-activated serine/threonine kinase 2.40702
RAB11B RAB11B, member RAS oncogene family 2.38788
ANK2 ankyrin 2, neuronal 2.34676
RNF112 ring finger protein 112 2.33526
COPS3 COP9 signalosome subunit 3 2.30697
PLCH1 phospholipase C, eta 1 2.29297
LCORL ligand dependent nuclear receptor corepressor-like 2.28303
GYPE glycophorin E (MNS blood group) 2.27593
DUSP15 dual specificity phosphatase 15 2.27593
DLX4 distal-less homeobox 4 2.26093
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 2.26058
ERF Ets2 repressor factor 2.19165
BCAP31 B-cell receptor-associated protein 31 2.19015
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 2.15461
TGFB3 transforming growth factor, beta 3 2.15261
TMEM150B transmembrane protein 150B 2.15261
CP ceruloplasmin (ferroxidase) 2.15261
ALX3 ALX homeobox 3 2.15261
TAC1 tachykinin, precursor 1 2.15261
C6ORF52 chromosome 6 open reading frame 52 2.13554
ZNF565 zinc finger protein 565 2.12591
TEKT5 tektin 5 2.11215
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 2.09391
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 2.08715
EMC9 ER membrane protein complex subunit 9 2.06112
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 2.05237
EID2B EP300 interacting inhibitor of differentiation 2B 2.05237
CLDN11 claudin 11 2.049
PRKG1 protein kinase, cGMP-dependent, type I 2.03076
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 2.02714
ANKRD12 ankyrin repeat domain 12 2.02603
TTLL6 tubulin tyrosine ligase-like family member 6 2.02603

decreased expression

Symbol Name Standardized Value
AKAP3 A kinase (PRKA) anchor protein 3 -3.49968
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) -3.49968
C2CD4C C2 calcium-dependent domain containing 4C -3.49968
ZNF488 zinc finger protein 488 -3.49968
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -3.49968
HLA-DOB major histocompatibility complex, class II, DO beta -3.49968
FBXO15 F-box protein 15 -3.49968
IFI6 interferon, alpha-inducible protein 6 -3.49968
EGFLAM EGF-like, fibronectin type III and laminin G domains -3.49968
ISM2 isthmin 2 -3.41489
DNAI2 dynein, axonemal, intermediate chain 2 -3.41489
MPZL2 myelin protein zero-like 2 -3.41489
TTBK1 tau tubulin kinase 1 -3.41489
STAR steroidogenic acute regulatory protein -3.41489
TMC8 transmembrane channel-like 8 -3.41489
CHAD chondroadherin -3.41489
AKAP14 A kinase (PRKA) anchor protein 14 -3.41489
MYBPC1 myosin binding protein C, slow type -3.41489
AZU1 azurocidin 1 -3.41489
ASB12 ankyrin repeat and SOCS box containing 12 -3.41489
SLC9C2 solute carrier family 9, member C2 (putative) -3.41489
CD68 CD68 molecule -3.41489
BBS5 Bardet-Biedl syndrome 5 -3.41489
TSPAN16 tetraspanin 16 -3.41489
TEX53 testis expressed 53 -3.41489
CMKLR2 chemerin chemokine-like receptor 2 -3.41489
LGALS14 lectin, galactoside-binding, soluble, 14 -3.41489
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -3.41489
REP15 RAB15 effector protein -3.41489
TEX29 testis expressed 29 -3.41489
GH2 growth hormone 2 -3.41489
TEX11 testis expressed 11 -3.41489
UPK1A uroplakin 1A -3.41489
OPLAH 5-oxoprolinase (ATP-hydrolysing) -3.41489
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -3.41489
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 -3.26875
CALCR calcitonin receptor -3.26023
USP35 ubiquitin specific peptidase 35 -3.26023
AACS acetoacetyl-CoA synthetase -3.25271
KIAA0319L KIAA0319-like -3.24436
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha -3.13392
MTM1 myotubularin 1 -3.081
WIZ widely interspaced zinc finger motifs -3.07005
CNN1 calponin 1, basic, smooth muscle -2.85887
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -2.85887
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta -2.85887
CHSY1 chondroitin sulfate synthase 1 -2.85887
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.82969
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.82308
MIMS2 mitochondrial inner membrane scaffold 2 -2.78257
RFXANK regulatory factor X-associated ankyrin-containing protein -2.77877
CDK3 cyclin-dependent kinase 3 -2.75691
PYCR3 pyrroline-5-carboxylate reductase 3 -2.75691
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -2.75212
ZNF174 zinc finger protein 174 -2.72612
RNASEK ribonuclease, RNase K -2.57592
RPS6KL1 ribosomal protein S6 kinase-like 1 -2.55388
FUOM fucose mutarotase -2.50207
AARSD1 alanyl-tRNA synthetase domain containing 1 -2.49999
KIRREL2 kin of IRRE like 2 (Drosophila) -2.48892
H4C1 H4 clustered histone 1 -2.48892
CADM4 cell adhesion molecule 4 -2.48892
PADI2 peptidyl arginine deiminase, type II -2.47334
CD300A CD300a molecule -2.47334
WHR1 winged helix repair factor 1 -2.4508
ESRP1 epithelial splicing regulatory protein 1 -2.39577
GDAP1 ganglioside induced differentiation associated protein 1 -2.39148
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -2.39148
FLT4 fms-related tyrosine kinase 4 -2.38788
MICA MHC class I polypeptide-related sequence A -2.37882
CBX4 chromobox homolog 4 -2.3759
CENPB centromere protein B, 80kDa -2.3759
AGBL1 ATP/GTP binding protein-like 1 -2.34676
TCL1B T-cell leukemia/lymphoma 1B -2.34676
SNAP25 synaptosomal-associated protein, 25kDa -2.33592
NINJ2 ninjurin 2 -2.33592
NREP neuronal regeneration related protein -2.33592
SLC67A1 solute carrier family 67 member 1 -2.33592
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -2.31503
CCL26 chemokine (C-C motif) ligand 26 -2.30697
ANKH ANKH inorganic pyrophosphate transport regulator -2.30697
SLC41A3 solute carrier family 41, member 3 -2.29999
SPTY2D1 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) -2.29859
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.2927
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.28851
FASTKD5 FAST kinase domains 5 -2.28469
KMT2A lysine (K)-specific methyltransferase 2A -2.25777
SHF Src homology 2 domain containing F -2.25244
STK39 serine threonine kinase 39 -2.25042
ZNF124 zinc finger protein 124 -2.24088
ARNT aryl hydrocarbon receptor nuclear translocator -2.23603
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -2.23079
HINT1 histidine triad nucleotide binding protein 1 -2.23043
ZNF251 zinc finger protein 251 -2.22964
MRPL9 mitochondrial ribosomal protein L9 -2.20942
LRRTM3 leucine rich repeat transmembrane neuronal 3 -2.20291
AHR aryl hydrocarbon receptor -2.19842
BICRA BRD4 interacting chromatin remodeling complex associated protein -2.19761
WDR83 WD repeat domain 83 -2.19761
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -2.19314
THAP7 THAP domain containing 7 -2.19193
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) -2.16226
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.15342
GSTCD glutathione S-transferase, C-terminal domain containing -2.15261
RPL27 ribosomal protein L27 -2.13079
AKR1C1 aldo-keto reductase family 1, member C1 -2.12591
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 -2.11945
SNRPG small nuclear ribonucleoprotein polypeptide G -2.10975
COPS7A COP9 signalosome subunit 7A -2.10975
PGAM1 phosphoglycerate mutase 1 (brain) -2.10741
PARD6A par-6 family cell polarity regulator alpha -2.105
TSN translin -2.105
E4F1 E4F transcription factor 1 -2.09835
INTS7 integrator complex subunit 7 -2.09241
IFFO2 intermediate filament family orphan 2 -2.08715
FBXO8 F-box protein 8 -2.08411
C2ORF42 chromosome 2 open reading frame 42 -2.08035
ZNF182 zinc finger protein 182 -2.07955
SSH2 slingshot protein phosphatase 2 -2.076
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -2.05237
STX1B syntaxin 1B -2.05237
FAM234A family with sequence similarity 234 member A -2.04877
NABP1 nucleic acid binding protein 1 -2.03993
SYMPK symplekin -2.03067
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.02752
ZNF875 zinc finger protein 875 -2.02714
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 -2.02603
MT1E metallothionein 1E -2.02603
KCTD9 potassium channel tetramerization domain containing 9 -2.02209
MED29 mediator complex subunit 29 -2.01705
SOAT1 sterol O-acyltransferase 1 -2.01298
GGCX gamma-glutamyl carboxylase -2.01067