PLXNA3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description plexin A3|This gene encodes a member of the plexin class of proteins. The encoded protein is a class 3 semaphorin receptor, and may be involved in cytoskeletal remodeling and as well as apoptosis. Studies of a similar gene in zebrafish suggest that it is important for axon pathfinding in the developing nervous system. This gene may be associated with tumor progression. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 55558)
External Link https://ncbi.nlm.nih.gov/gene/55558
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Genes

499 genes differentially expressed following the PLXNA3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0132539
TACSTD2 tumor-associated calcium signal transducer 2 0.0131168
MSLN mesothelin 0.0122692
KRT15 keratin 15, type I 0.0115365
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0108601
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.0108592
OXA1L oxidase (cytochrome c) assembly 1-like 0.0107597
RGCC regulator of cell cycle 0.0107432
SLPI secretory leukocyte peptidase inhibitor 0.0105133
CLDN10 claudin 10 0.00997207
AQP3 aquaporin 3 (Gill blood group) 0.00961105
BGN biglycan 0.00948029
MAL mal, T-cell differentiation protein 0.00945228
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00920598
TRIM29 tripartite motif containing 29 0.00892671
EMP1 epithelial membrane protein 1 0.00889779
PUF60 poly-U binding splicing factor 60KDa 0.00883615
COG7 component of oligomeric golgi complex 7 0.0088229
AKR1C2 aldo-keto reductase family 1, member C2 0.00875957
AOC1 amine oxidase, copper containing 1 0.00860542
CEMIP cell migration inducing protein, hyaluronan binding 0.00860537
KRT13 keratin 13, type I 0.00857054
GSTP1 glutathione S-transferase pi 1 0.00846435
FABP4 fatty acid binding protein 4, adipocyte 0.00843602
BHLHE41 basic helix-loop-helix family, member e41 0.00838228
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00830538
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.00821729
PROM1 prominin 1 0.00820497
CCN2 cellular communication network factor 2 0.00812637
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00811062
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0080751
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00806395
TSPAN8 tetraspanin 8 0.00801639
UFM1 ubiquitin-fold modifier 1 0.00800317
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00793957
MMP10 matrix metallopeptidase 10 0.0078543
MECOM MDS1 and EVI1 complex locus 0.00784713
PODXL podocalyxin-like 0.00783477
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00782343
MGP matrix Gla protein 0.00772996
CFH complement factor H 0.00770873
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00769322
TM4SF1 transmembrane 4 L six family member 1 0.00766763
S100A2 S100 calcium binding protein A2 0.00766076
CP ceruloplasmin (ferroxidase) 0.0076213
NEBL nebulette 0.00753151
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00752921
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00751945
KDM5D lysine (K)-specific demethylase 5D 0.00738443
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00737459
VSNL1 visinin-like 1 0.00727886
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.00725969
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00721673
TSPAN1 tetraspanin 1 0.00717755
CSTA cystatin A (stefin A) 0.00717718
AOX1 aldehyde oxidase 1 0.00714719
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00708455
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00707543
EAF2 ELL associated factor 2 0.00703563
IGLL1 immunoglobulin lambda-like polypeptide 1 0.0070293
FZD10 frizzled class receptor 10 0.00702057
CLIC5 chloride intracellular channel 5 0.00701867
AKR1C3 aldo-keto reductase family 1, member C3 0.00699522
PEBP1 phosphatidylethanolamine binding protein 1 0.00699277
GPI glucose-6-phosphate isomerase 0.00695434
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00692507
KLK6 kallikrein-related peptidase 6 0.00691946
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00685725
MSMB microseminoprotein, beta- 0.00683236
AQP1 aquaporin 1 (Colton blood group) 0.00675347
AKR1C1 aldo-keto reductase family 1, member C1 0.00674517
EPS8L2 EPS8-like 2 0.00674093
PKP4 plakophilin 4 0.00672322
GMDS GDP-mannose 4,6-dehydratase 0.00671744
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.00671439
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0066813
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00667429
ABLIM1 actin binding LIM protein 1 0.00665564
ISG20 interferon stimulated exonuclease gene 20kDa 0.00663518
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00663235
TRIB2 tribbles pseudokinase 2 0.00659467
NCK1 NCK adaptor protein 1 0.00659446
LRP4 low density lipoprotein receptor-related protein 4 0.00656344
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00655291
BAG3 BCL2-associated athanogene 3 0.00653878
ITGB1BP1 integrin beta 1 binding protein 1 0.00651287
EPHA2 EPH receptor A2 0.00648897
DOK5 docking protein 5 0.00647816
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00646096
CSRP2 cysteine and glycine-rich protein 2 0.00645564
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00643834
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00640648
C6ORF48 chromosome 6 open reading frame 48 0.00639091
ZNF185 zinc finger protein 185 (LIM domain) 0.00638642
FERMT1 fermitin family member 1 0.00635935
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00631592
AEBP1 AE binding protein 1 0.00627452
TMPRSS4 transmembrane protease, serine 4 0.00625364
C9ORF16 chromosome 9 open reading frame 16 0.00624855
HSPA1A heat shock 70kDa protein 1A 0.00624786
SPON1 spondin 1, extracellular matrix protein 0.00622918
SMAD6 SMAD family member 6 0.00620989
KRT5 keratin 5, type II 0.00617582
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00615449
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.00613295
PCNA proliferating cell nuclear antigen 0.0061268
DMTF1 cyclin D binding myb-like transcription factor 1 0.00612355
PWP1 PWP1 homolog (S. cerevisiae) 0.00611576
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.0061029
C9ORF3 chromosome 9 open reading frame 3 0.00605215
CSTB cystatin B (stefin B) 0.0060462
SPRED2 sprouty-related, EVH1 domain containing 2 0.00602325
EPHB2 EPH receptor B2 0.00601555
STATH statherin 0.00599254
CHPT1 choline phosphotransferase 1 0.00598728
MUC16 mucin 16, cell surface associated 0.00598644
NPAS2 neuronal PAS domain protein 2 0.00597456
KRT14 keratin 14, type I 0.00594679
ADIRF adipogenesis regulatory factor 0.00593714
MRPS31 mitochondrial ribosomal protein S31 0.00592017
AHCY adenosylhomocysteinase 0.00589277
HYAL1 hyaluronoglucosaminidase 1 0.00588663
SCEL sciellin 0.00588655
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00588593
LHFP lipoma HMGIC fusion partner 0.00585103
CD9 CD9 molecule 0.00584582
HAT1 histone acetyltransferase 1 0.00581873
P3H2 prolyl 3-hydroxylase 2 0.00581349
MUC4 mucin 4, cell surface associated 0.00580587
ATF4 activating transcription factor 4 0.00580191
PLLP plasmolipin 0.00577506
HBEGF heparin-binding EGF-like growth factor 0.00577124
RGS13 regulator of G-protein signaling 13 0.00574866
TCTA T-cell leukemia translocation altered 0.00573342
FBLN5 fibulin 5 0.00571377
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00570086
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.00568753
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00567679
COQ8A coenzyme Q8A 0.00567225
AMH anti-Mullerian hormone 0.00566482
PITX1 paired-like homeodomain 1 0.0056532
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00563884
KLF5 Kruppel-like factor 5 (intestinal) 0.00563824
KLK10 kallikrein-related peptidase 10 0.00563098
GPX3 glutathione peroxidase 3 0.00561519
FXYD3 FXYD domain containing ion transport regulator 3 0.0056132
FAM171A1 family with sequence similarity 171, member A1 0.0056119
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 0.00559044
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00558922
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00558761
LTBP2 latent transforming growth factor beta binding protein 2 0.00557581
AHNAK2 AHNAK nucleoprotein 2 0.00557266
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00556598
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 0.00553539
WFDC2 WAP four-disulfide core domain 2 0.00553371
DIPK1A divergent protein kinase domain 1A 0.00552283
MALL mal, T-cell differentiation protein-like 0.00551194
ASS1 argininosuccinate synthase 1 0.0054999
COMP cartilage oligomeric matrix protein 0.00549843
NINJ1 ninjurin 1 0.00548886
LTA4H leukotriene A4 hydrolase 0.00546998
NANS N-acetylneuraminic acid synthase 0.00545373
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00540141
KRT6A keratin 6A, type II 0.00540003
KLK11 kallikrein-related peptidase 11 0.00538659
SIVA1 SIVA1, apoptosis-inducing factor 0.0053766
PI3 peptidase inhibitor 3, skin-derived 0.00537494
IER3 immediate early response 3 0.00536886
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.00536435
ADD3 adducin 3 (gamma) 0.00535896
TOR1A torsin family 1, member A (torsin A) 0.0053337
PSCA prostate stem cell antigen 0.00532846
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00532622
REXO2 RNA exonuclease 2 0.00532556
MPZL2 myelin protein zero-like 2 0.00529216
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.00527477
DPYS dihydropyrimidinase 0.0052552
CETN2 centrin, EF-hand protein, 2 0.00524851
RGS10 regulator of G-protein signaling 10 0.00524746
RPL14 ribosomal protein L14 0.00524359
SDC1 syndecan 1 0.00523987
LAMP3 lysosomal-associated membrane protein 3 0.00523557
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00523067
CYB561 cytochrome b561 0.00522672
CYB5A cytochrome b5 type A (microsomal) 0.00520231
INHBA inhibin, beta A 0.00519199
NDRG1 N-myc downstream regulated 1 0.00519148
MEIS1 Meis homeobox 1 0.00518897
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00517618
CLCA4 chloride channel accessory 4 0.0051743
SCRG1 stimulator of chondrogenesis 1 0.00516642
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.00515237
EIF3K eukaryotic translation initiation factor 3, subunit K 0.00514784
KRT7 keratin 7, type II 0.00514115
COL11A1 collagen, type XI, alpha 1 0.00513817
MYH10 myosin, heavy chain 10, non-muscle 0.0051373
CLDN7 claudin 7 0.00513118
PLS1 plastin 1 0.00512411
MGLL monoglyceride lipase 0.00511744
TSPO translocator protein (18kDa) 0.00509181
ERBB3 erb-b2 receptor tyrosine kinase 3 0.00508797
ANOS1 anosmin 1 0.00507665
LGALS4 lectin, galactoside-binding, soluble, 4 0.00505915
TAGLN transgelin 0.00505359
FMO3 flavin containing monooxygenase 3 0.005048
RIPK4 receptor-interacting serine-threonine kinase 4 0.0050325
EPCAM epithelial cell adhesion molecule 0.00502975
ESRP1 epithelial splicing regulatory protein 1 0.00501695
NFE2L2 nuclear factor, erythroid 2-like 2 0.00501652
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00497549
FXYD6 FXYD domain containing ion transport regulator 6 0.00497371
TPM2 tropomyosin 2 (beta) 0.00496984
LAMA3 laminin, alpha 3 0.00496152
LIG1 ligase I, DNA, ATP-dependent 0.0049569
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00495658
ANXA3 annexin A3 0.00493718
C7 complement component 7 0.00493615
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.00492962
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.00492232
MT1X metallothionein 1X 0.0049196
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00491586
CHRDL1 chordin-like 1 0.00491334
CIB1 calcium and integrin binding 1 (calmyrin) 0.004913
TMEM176B transmembrane protein 176B 0.00490826
DNTT DNA nucleotidylexotransferase 0.00489011
GPX2 glutathione peroxidase 2 0.00487078
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.004865
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00485617
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase 0.00485462
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00485307
TGFA transforming growth factor, alpha 0.00484705
STON1 stonin 1 0.00484613
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 0.00483574
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00483147
EMC2 ER membrane protein complex subunit 2 0.00482553
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00482396
MREG melanoregulin 0.00479657
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00478791
SELE selectin E 0.0047844
DCK deoxycytidine kinase 0.0047811
IPO7 importin 7 0.0047736
ITGB4 integrin, beta 4 0.00476389
SULF1 sulfatase 1 0.00476204
ELN elastin 0.00474539
C1R complement component 1, r subcomponent 0.00473416
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00472971
EFNA1 ephrin-A1 0.00472609
MME membrane metallo-endopeptidase 0.00472113
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00472075
ITM2C integral membrane protein 2C 0.00471021

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0156826
COL4A5 collagen, type IV, alpha 5 -0.0104122
REEP1 receptor accessory protein 1 -0.0102013
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.0101056
PEG3 paternally expressed 3 -0.0100659
CA2 carbonic anhydrase II -0.0100618
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.0100505
NIBAN1 niban apoptosis regulator 1 -0.00991929
MAP7 microtubule-associated protein 7 -0.00976973
PLIN2 perilipin 2 -0.00970067
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00966444
F13A1 coagulation factor XIII, A1 polypeptide -0.00965751
CADM1 cell adhesion molecule 1 -0.00957147
TFPI2 tissue factor pathway inhibitor 2 -0.00951031
CDC20 cell division cycle 20 -0.00913367
ZNF91 zinc finger protein 91 -0.00884978
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00872595
STK10 serine/threonine kinase 10 -0.00862285
NBPF10 neuroblastoma breakpoint family, member 10 -0.00855997
TNIK TRAF2 and NCK interacting kinase -0.008226
TENT5A terminal nucleotidyltransferase 5A -0.00816178
CGA glycoprotein hormones, alpha polypeptide -0.00787457
MAGEA3 melanoma antigen family A3 -0.00778545
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0077754
DCT dopachrome tautomerase -0.00773206
BEX1 brain expressed, X-linked 1 -0.00767525
GSTM3 glutathione S-transferase mu 3 (brain) -0.00746986
DUSP5 dual specificity phosphatase 5 -0.00738495
BSG basigin (Ok blood group) -0.00737759
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -0.00736884
DSE dermatan sulfate epimerase -0.00725676
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00722126
PRKCB protein kinase C, beta -0.00721283
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00721005
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00719769
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00707419
HHEX hematopoietically expressed homeobox -0.00706112
ARHGAP29 Rho GTPase activating protein 29 -0.00703663
ZBTB38 zinc finger and BTB domain containing 38 -0.00702409
BTG2 BTG family, member 2 -0.00699964
SH3BGRL SH3 domain binding glutamate-rich protein like -0.00696143
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00689073
RTN2 reticulon 2 -0.0068383
TMEM45A transmembrane protein 45A -0.00680763
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00679589
CPVL carboxypeptidase, vitellogenic-like -0.0067945
GOLM1 golgi membrane protein 1 -0.00672612
ATP7A ATPase, Cu++ transporting, alpha polypeptide -0.00669559
MMP9 matrix metallopeptidase 9 -0.00665787
SNX7 sorting nexin 7 -0.00664683
IL2RB interleukin 2 receptor, beta -0.00663282
MOCOS molybdenum cofactor sulfurase -0.00661492
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00661039
ZBTB20 zinc finger and BTB domain containing 20 -0.00659621
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.00658823
NID1 nidogen 1 -0.00657573
PON2 paraoxonase 2 -0.00657129
MMD monocyte to macrophage differentiation-associated -0.00656956
PEG10 paternally expressed 10 -0.00654898
ZNF160 zinc finger protein 160 -0.00654302
NVL nuclear VCP-like -0.00646517
MEX3D mex-3 RNA binding family member D -0.00643311
NCAM1 neural cell adhesion molecule 1 -0.0064183
SLC38A2 solute carrier family 38, member 2 -0.00640723
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.0064015
WSB1 WD repeat and SOCS box containing 1 -0.006397
RNF11 ring finger protein 11 -0.00638346
MIR22HG MIR22 host gene -0.00637015
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -0.00629705
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00626954
SCGB2A2 secretoglobin, family 2A, member 2 -0.00626302
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00626274
TGFB1 transforming growth factor, beta 1 -0.00625912
SCG5 secretogranin V -0.0062342
CHGB chromogranin B -0.00623202
SCARB2 scavenger receptor class B, member 2 -0.00621995
GOLGA8A golgin A8 family, member A -0.00620897
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00617115
HOXC6 homeobox C6 -0.00617026
ABHD17A abhydrolase domain containing 17A -0.00614545
HIC2 hypermethylated in cancer 2 -0.00613501
MAPK1 mitogen-activated protein kinase 1 -0.00612427
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -0.00610525
COL6A2 collagen, type VI, alpha 2 -0.00607806
SDF4 stromal cell derived factor 4 -0.00606346
DCLK1 doublecortin-like kinase 1 -0.00602217
ERBIN erbb2 interacting protein -0.00599152
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00597826
CHKB choline kinase beta -0.00596634
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0059431
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00592944
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00591793
APOB apolipoprotein B -0.00590511
RAP2A RAP2A, member of RAS oncogene family -0.0058923
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00587477
PAX6 paired box 6 -0.00584142
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00583042
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00582664
PHACTR2 phosphatase and actin regulator 2 -0.00577715
FST follistatin -0.00577421
AFP alpha-fetoprotein -0.00575039
PLXNC1 plexin C1 -0.00574357
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.0057242
PTP4A1 protein tyrosine phosphatase type IVA, member 1 -0.00571508
OSTM1 osteopetrosis associated transmembrane protein 1 -0.00570682
CPB1 carboxypeptidase B1 (tissue) -0.00568982
NOTCH2NL notch 2 N-terminal like -0.0056815
TGFBI transforming growth factor, beta-induced, 68kDa -0.00566285
DHDDS dehydrodolichyl diphosphate synthase -0.005656
ALAS2 5'-aminolevulinate synthase 2 -0.00565441
ITGB7 integrin, beta 7 -0.00565147
CPM carboxypeptidase M -0.00563049
ZBTB18 zinc finger and BTB domain containing 18 -0.00562223
APOA1 apolipoprotein A-I -0.0056018
BBX bobby sox homolog (Drosophila) -0.00559394
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.0055938
CCDC92 coiled-coil domain containing 92 -0.00558966
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) -0.00558572
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.00557044
GCG glucagon -0.00553331
ZNF721 zinc finger protein 721 -0.0055306
MTF2 metal response element binding transcription factor 2 -0.0055295
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00550267
CALML5 calmodulin-like 5 -0.00550021
RCAN2 regulator of calcineurin 2 -0.00548492
QKI QKI, KH domain containing, RNA binding -0.00546799
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00546125
SHOX2 short stature homeobox 2 -0.00544805
HLA-DMB major histocompatibility complex, class II, DM beta -0.00543267
DLK1 delta-like 1 homolog (Drosophila) -0.00542985
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -0.00541568
AGR2 anterior gradient 2 -0.00541415
SLC38A1 solute carrier family 38, member 1 -0.00541277
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00540241
STX8 syntaxin 8 -0.00539917
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00535879
VCL vinculin -0.00535309
CD99 CD99 molecule -0.00534491
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00534227
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00533555
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.00533429
MAGEA12 melanoma antigen family A12 -0.00532288
PPIF peptidylprolyl isomerase F -0.00531652
PBK PDZ binding kinase -0.00530935
HAUS2 HAUS augmin-like complex, subunit 2 -0.00529623
PLEK pleckstrin -0.00527562
MSX1 msh homeobox 1 -0.0052723
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.00526216
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -0.00525867
PLCL2 phospholipase C-like 2 -0.00523518
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00522554
DSC1 desmocollin 1 -0.00522379
IL13RA2 interleukin 13 receptor, alpha 2 -0.00522328
CALD1 caldesmon 1 -0.00522044
KRT2 keratin 2, type II -0.00521214
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00521192
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.00520649
NLRP2 NLR family, pyrin domain containing 2 -0.00520171
SORT1 sortilin 1 -0.00518281
RNPS1 RNA binding protein S1, serine-rich domain -0.0051633
MEIS2 Meis homeobox 2 -0.00513396
SCGN secretagogin, EF-hand calcium binding protein -0.00512994
ACLY ATP citrate lyase -0.00511891
RHOBTB3 Rho-related BTB domain containing 3 -0.00509384
COL4A6 collagen, type IV, alpha 6 -0.0050934
MNDA myeloid cell nuclear differentiation antigen -0.0050746
MAGEA1 melanoma antigen family A1 -0.00506455
LSP1 lymphocyte-specific protein 1 -0.00505332
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00502745
PTCH1 patched 1 -0.00502643
GNAS GNAS complex locus -0.00502579
ELOVL5 ELOVL fatty acid elongase 5 -0.00501879
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.00501067
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.00498329
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00497678
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00497562
SSX1 synovial sarcoma, X breakpoint 1 -0.0049693
BRD4 bromodomain containing 4 -0.00496665
CPA3 carboxypeptidase A3 (mast cell) -0.00496368
SPON2 spondin 2, extracellular matrix protein -0.00495876
ADAP2 ArfGAP with dual PH domains 2 -0.00495359
GALC galactosylceramidase -0.00494296
CCNL2 cyclin L2 -0.00494272
ZNF266 zinc finger protein 266 -0.00492845
LONP2 lon peptidase 2, peroxisomal -0.00492108
LYST lysosomal trafficking regulator -0.0049189
MINK1 misshapen-like kinase 1 -0.00491016
REG3A regenerating islet-derived 3 alpha -0.00490981
NADK NAD kinase -0.00490522
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00489973
PDLIM1 PDZ and LIM domain 1 -0.00489189
PPP4R3A protein phosphatase 4 regulatory subunit 3A -0.00488966
SHTN1 shootin 1 -0.00488047
SFRP1 secreted frizzled-related protein 1 -0.00487453
NPTX1 neuronal pentraxin I -0.00487325
RNF167 ring finger protein 167 -0.00486926
LAPTM4B lysosomal protein transmembrane 4 beta -0.00485929
CNN3 calponin 3, acidic -0.00485521
APMAP adipocyte plasma membrane associated protein -0.00484584
DGKD diacylglycerol kinase, delta 130kDa -0.0048406
CDK17 cyclin-dependent kinase 17 -0.00482751
ABHD3 abhydrolase domain containing 3 -0.00482522
APOA2 apolipoprotein A-II -0.00482296
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -0.00479213
DPYSL3 dihydropyrimidinase-like 3 -0.00479159
GPC3 glypican 3 -0.00478751
PLXNA2 plexin A2 -0.00478745
CDC34 cell division cycle 34 -0.00478098
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -0.00476594
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.00476255
ADAM9 ADAM metallopeptidase domain 9 -0.00475733
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene) -0.00475692
PFN2 profilin 2 -0.00474783
LIN28A lin-28 homolog A (C. elegans) -0.00474065
PMM2 phosphomannomutase 2 -0.00473818
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00473763
RNF4 ring finger protein 4 -0.00472396
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00472291
MFSD10 major facilitator superfamily domain containing 10 -0.00470337
ATP10D ATPase, class V, type 10D -0.00470253
BMP2K BMP2 inducible kinase -0.00469777
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.00468908
TSPAN5 tetraspanin 5 -0.00468619
ARG1 arginase 1 -0.00468497
CAB39 calcium binding protein 39 -0.00468358
RTN1 reticulon 1 -0.00467112
SRGN serglycin -0.00466462
FOXF2 forkhead box F2 -0.00464837
CKS2 CDC28 protein kinase regulatory subunit 2 -0.00463854
ZNF43 zinc finger protein 43 -0.00463723
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -0.00462781
TDO2 tryptophan 2,3-dioxygenase -0.00461873
SPEN spen family transcriptional repressor -0.00461668
ZNF117 zinc finger protein 117 -0.00461018
PDPK1 3-phosphoinositide dependent protein kinase 1 -0.00460566
CLGN calmegin -0.00459543
RTL8C retrotransposon Gag like 8C -0.0045933
COMMD8 COMM domain containing 8 -0.00458143
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00457394
PRSS8 protease, serine, 8 -0.00457334
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.00457068
CA12 carbonic anhydrase XII -0.00455808
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00455659
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00455641
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 -0.00454266
PPIC peptidylprolyl isomerase C (cyclophilin C) -0.00454095
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00453912
CHGA chromogranin A -0.00453889
NPTX2 neuronal pentraxin II -0.00453381