PMC12082120-mmc1.xlsx-Table_S1_-Diffusion-LPS_IRF6 Gene Set

Dataset Rummagene Transcription Factor Associations 2026
Category genomics
Type transcription factor
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Genes

452 target genes of the PMC12082120-mmc1.xlsx-Table_S1_-Diffusion-LPS_IRF6 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

Symbol Name
AAMP angio-associated, migratory cell protein
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTB actin, beta
ACTN2 actinin, alpha 2
ACVR1B activin A receptor, type IB
ACVR1C activin A receptor, type IC
ACVRL1 activin A receptor type II-like 1
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMER1 APC membrane recruitment protein 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANKRD23 ankyrin repeat domain 23
APC adenomatous polyposis coli
ARNT aryl hydrocarbon receptor nuclear translocator
ARRB2 arrestin, beta 2
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide
AXIN1 axin 1
AXIN2 axin 2
AXL AXL receptor tyrosine kinase
BAG4 BCL2-associated athanogene 4
BAIAP2 BAI1-associated protein 2
BAMBI BMP and activin membrane-bound inhibitor
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC5 baculoviral IAP repeat containing 5
BPI bactericidal/permeability-increasing protein
BTK Bruton agammaglobulinemia tyrosine kinase
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARM1 coactivator-associated arginine methyltransferase 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBFB core-binding factor, beta subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBY1 chibby homolog 1 (Drosophila)
CCDC88C coiled-coil domain containing 88C
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCND1 cyclin D1
CD14 CD14 molecule
CD22 CD22 molecule
CDC42 cell division cycle 42
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CHD1 chromodomain helicase DNA binding protein 1
CHD8 chromodomain helicase DNA binding protein 8
CHUK conserved helix-loop-helix ubiquitous kinase
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCF1 cardiotrophin-like cytokine factor 1
CLIP3 CAP-GLY domain containing linker protein 3
CNTF ciliary neurotrophic factor
CNTFR ciliary neurotrophic factor receptor
CNTN1 contactin 1
COL10A1 collagen, type X, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL9A1 collagen, type IX, alpha 1
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRLF1 cytokine receptor-like factor 1
CSNK1A1 casein kinase 1, alpha 1
CSNK1E casein kinase 1, epsilon
CSNK1G2 casein kinase 1, gamma 2
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTBP1 C-terminal binding protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTF1 cardiotrophin 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXXC4 CXXC finger protein 4
CXXC5 CXXC finger protein 5
CYBB cytochrome b-245, beta polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DMD dystrophin
DNER delta/notch-like EGF repeat containing
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
EBAG9 estrogen receptor binding site associated, antigen, 9
ECSIT ECSIT signalling integrator
EDN1 endothelin 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ESR1 estrogen receptor 1
FADD Fas (TNFRSF6)-associated via death domain
FERMT2 fermitin family member 2
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FKBP4 FK506 binding protein 4, 59kDa
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXA1 forkhead box A1
FOXH1 forkhead box H1
FOXO3 forkhead box O3
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD3 frizzled class receptor 3
FZD4 frizzled class receptor 4
GATA3 GATA binding protein 3
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GLRX3 glutaredoxin 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPER1 G protein-coupled estrogen receptor 1
GRB2 growth factor receptor-bound protein 2
GREB1 growth regulation by estrogen in breast cancer 1
GREM1 gremlin 1, DAN family BMP antagonist
GRK2 G protein-coupled receptor kinase 2
GSK3B glycogen synthase kinase 3 beta
GTF2IRD1 GTF2I repeat domain containing 1
H2AC6 H2A clustered histone 6
H3C1 H3 clustered histone 1
HAND2 heart and neural crest derivatives expressed 2
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HDAC4 histone deacetylase 4
HDAC6 histone deacetylase 6
HDAC9 histone deacetylase 9
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMGB1 high mobility group box 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
IGF1R insulin-like growth factor 1 receptor
IHH indian hedgehog
IKBIP IKBKB interacting protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL11 interleukin 11
IL11RA interleukin 11 receptor, alpha
IL12B interleukin 12B
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL4 interleukin 4
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
ITCH itchy E3 ubiquitin protein ligase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAG1 jagged 1
JAG2 jagged 2
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KAT5 K(lysine) acetyltransferase 5
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNK4 potassium channel, two pore domain subfamily K, member 4
KCTD6 potassium channel tetramerization domain containing 6
KDM1A lysine (K)-specific demethylase 1A
KDM4B lysine (K)-specific demethylase 4B
KDR kinase insert domain receptor
KLF2 Kruppel-like factor 2
KMT2D lysine (K)-specific methyltransferase 2D
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMA2 laminin, alpha 2
LBP lipopolysaccharide binding protein
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGALS3 lectin, galactoside-binding, soluble, 3
LIF leukemia inhibitory factor
LIFR leukemia inhibitory factor receptor alpha
LMNA lamin A/C
LRRC14 leucine rich repeat containing 14
LTBP4 latent transforming growth factor beta binding protein 4
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MALT1 MALT1 paracaspase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MED1 mediator complex subunit 1
MEF2C myocyte enhancer factor 2C
MEN1 multiple endocrine neoplasia I
MIB2 mindbomb E3 ubiquitin protein ligase 2
MKX mohawk homeobox
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MRTFA myocardin related transcription factor A
MSX2 msh homeobox 2
MTMR4 myotubularin related protein 4
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK myosin light chain kinase
N4BP1 NEDD4 binding protein 1
NBEA neurobeachin
NCK1 NCK adaptor protein 1
NCOA1 nuclear receptor coactivator 1
NCOA3 nuclear receptor coactivator 3
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX3-2 NK3 homeobox 2
NLK nemo-like kinase
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
NOS1 nitric oxide synthase 1 (neuronal)
NOTCH1 notch 1
NPHP4 nephronophthisis 4
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
NRP2 neuropilin 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUMB numb homolog (Drosophila)
OPTN optineurin
OSM oncostatin M
OSMR oncostatin M receptor
OTULIN OTU deubiquitinase with linear linkage specificity
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PANX1 pannexin 1
PARP1 poly (ADP-ribose) polymerase 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PFKP phosphofructokinase, platelet
PFN1 profilin 1
PGR progesterone receptor
PIEZO1 piezo-type mechanosensitive ion channel component 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEC plectin
PMEPA1 prostate transmembrane protein, androgen induced 1
PORCN porcupine homolog (Drosophila)
POU2F1 POU class 2 homeobox 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRG4 proteoglycan 4
PRICKLE1 prickle homolog 1 (Drosophila)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRMT1 protein arginine methyltransferase 1
PTCRA pre T-cell antigen receptor alpha
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXN paxillin
PYCR1 pyrroline-5-carboxylate reductase 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACK1 receptor for activated C kinase 1
RALGDS ral guanine nucleotide dissociation stimulator
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RBBP5 retinoblastoma binding protein 5
RBM14 RNA binding motif protein 14
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNF111 ring finger protein 111
RNF146 ring finger protein 146
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX2 runt-related transcription factor 2
RUVBL1 RuvB-like AAA ATPase 1
RYK receptor-like tyrosine kinase
S1PR3 sphingosine-1-phosphate receptor 3
SARM1 sterile alpha and TIR motif containing 1
SATB2 SATB homeobox 2
SCRIB scribbled planar cell polarity protein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2D2A SH2 domain containing 2A
SHB Src homology 2 domain containing adaptor protein B
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNW1 SNW domain containing 1
SNX3 sorting nexin 3
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SP7 Sp7 transcription factor
SPATA2 spermatogenesis associated 2
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSPN sarcospan
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STRAP serine/threonine kinase receptor associated protein
STRN striatin, calmodulin binding protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYK spleen tyrosine kinase
TANK TRAF family member-associated NFKB activator
TBP TATA box binding protein
TCAP titin-cap
TEAD2 TEA domain family member 2
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TJP1 tight junction protein 1
TJP2 tight junction protein 2
TLE3 transducin-like enhancer of split 3
TLE5 TLE family member 5, transcriptional modulator
TLR4 toll-like receptor 4
TMED5 transmembrane emp24 protein transport domain containing 5
TMEM63A transmembrane protein 63A
TNF tumor necrosis factor
TNIP2 TNFAIP3 interacting protein 2
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM33 tripartite motif containing 33
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRRAP transformation/transcription domain-associated protein
TTN titin
TWIST1 twist family bHLH transcription factor 1
TYK2 tyrosine kinase 2
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2M ubiquitin-conjugating enzyme E2M
UCMA upper zone of growth plate and cartilage matrix associated
UHMK1 U2AF homology motif (UHM) kinase 1
ULK1 unc-51 like autophagy activating kinase 1
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP18 ubiquitin specific peptidase 18
USP34 ubiquitin specific peptidase 34
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
VANGL2 VANGL planar cell polarity protein 2
VAV1 vav 1 guanine nucleotide exchange factor
WIF1 WNT inhibitory factor 1
WLS wntless Wnt ligand secretion mediator
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
WWC1 WW and C2 domain containing 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWTR1 WW domain containing transcription regulator 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF217 zinc finger protein 217
ZNF521 zinc finger protein 521
ZRANB1 zinc finger, RAN-binding domain containing 1