PMC12451251-BMRI-2025-9283631-s001.xlsx-Target-STAT3_STAT3 Gene Set

Dataset Rummagene Transcription Factor Associations 2026
Category genomics
Type transcription factor
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Genes

398 target genes of the PMC12451251-BMRI-2025-9283631-s001.xlsx-Target-STAT3_STAT3 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
ADK adenosine kinase
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
ADRA1A adrenoceptor alpha 1A
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALPL alkaline phosphatase, liver/bone/kidney
AMPD3 adenosine monophosphate deaminase 3
AMY1A amylase, alpha 1A (salivary)
ANPEP alanyl (membrane) aminopeptidase
APH1A APH1A gamma secretase subunit
APH1B APH1B gamma secretase subunit
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARG1 arginase 1
AURKA aurora kinase A
AURKB aurora kinase B
AVPR1A arginine vasopressin receptor 1A
AVPR2 arginine vasopressin receptor 2
AXL AXL receptor tyrosine kinase
BACE1 beta-site APP-cleaving enzyme 1
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BMX BMX non-receptor tyrosine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CA13 carbonic anhydrase XIII
CA14 carbonic anhydrase XIV
CA2 carbonic anhydrase II
CA3 carbonic anhydrase III
CA4 carbonic anhydrase IV
CA5A carbonic anhydrase VA, mitochondrial
CA6 carbonic anhydrase VI
CA7 carbonic anhydrase VII
CA9 carbonic anhydrase IX
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNB3 cyclin B3
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCR1 chemokine (C-C motif) receptor 1
CD38 CD38 molecule
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK6 cyclin-dependent kinase 6
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CES2 carboxylesterase 2
CFD complement factor D (adipsin)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CLK1 CDC-like kinase 1
CLK2 CDC-like kinase 2
CLK4 CDC-like kinase 4
CMA1 chymase 1, mast cell
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CRHR1 corticotropin releasing hormone receptor 1
CSF1R colony stimulating factor 1 receptor
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CXCR1 chemokine (C-X-C motif) receptor 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYSLTR1 cysteinyl leukotriene receptor 1
DAO D-amino-acid oxidase
DAPK1 death-associated protein kinase 1
DCTPP1 dCTP pyrophosphatase 1
DGAT1 diacylglycerol O-acyltransferase 1
DHFR dihydrofolate reductase
DNM1 dynamin 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DUSP3 dual specificity phosphatase 3
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EPHA2 EPH receptor A2
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
ESRRB estrogen-related receptor beta
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAAH fatty acid amide hydrolase
FASN fatty acid synthase
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FNTA farnesyltransferase, CAAX box, alpha
FNTB farnesyltransferase, CAAX box, beta
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXO1 forkhead box O1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA1 glucosylceramidase beta 1
GBA2 glucosidase, beta (bile acid) 2
GCGR glucagon receptor
GLO1 glyoxalase I
GPR35 G protein-coupled receptor 35
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRK1 G protein-coupled receptor kinase 1
GRK2 G protein-coupled receptor kinase 2
GRK6 G protein-coupled receptor kinase 6
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HDAC8 histone deacetylase 8
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HK2 hexokinase 2
HPSE heparanase
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA8 heat shock 70kDa protein 8
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1R insulin-like growth factor 1 receptor
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL2 interleukin 2
IL6ST interleukin 6 signal transducer
INSR insulin receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS8 lectin, galactoside-binding, soluble, 8
LNPEP leucyl/cystinyl aminopeptidase
LRRK2 leucine-rich repeat kinase 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTB4R leukotriene B4 receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2K1 mitogen-activated protein kinase kinase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MCHR1 melanin-concentrating hormone receptor 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MST1R macrophage stimulating 1 receptor
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYLK myosin light chain kinase
NCSTN nicastrin
NEK1 NIMA-related kinase 1
NEK2 NIMA-related kinase 2
NEK6 NIMA-related kinase 6
NMUR2 neuromedin U receptor 2
NOS2 nitric oxide synthase 2, inducible
NOX4 NADPH oxidase 4
NQO2 NAD(P)H dehydrogenase, quinone 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUAK1 NUAK family, SNF1-like kinase, 1
OGA O-GlcNAcase
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
OXTR oxytocin receptor
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PARP1 poly (ADP-ribose) polymerase 1
PDE10A phosphodiesterase 10A
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4B phosphodiesterase 4B, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PITRM1 pitrilysin metallopeptidase 1
PKN1 protein kinase N1
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLK1 polo-like kinase 1
PNMT phenylethanolamine N-methyltransferase
POLB polymerase (DNA directed), beta
PRCP prolylcarboxypeptidase (angiotensinase C)
PRF1 perforin 1 (pore forming protein)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCH protein kinase C, eta
PRKCZ protein kinase C, zeta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTAFR platelet-activating factor receptor
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRS protein tyrosine phosphatase, receptor type, S
PYGL phosphorylase, glycogen, liver
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
REN renin
RET ret proto-oncogene
RIPK2 receptor-interacting serine-threonine kinase 2
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
S1PR1 sphingosine-1-phosphate receptor 1
S1PR3 sphingosine-1-phosphate receptor 3
SCN9A sodium channel, voltage gated, type IX alpha subunit
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SMO smoothened, frizzled class receptor
SOAT1 sterol O-acyltransferase 1
SOAT2 sterol O-acyltransferase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYK spleen tyrosine kinase
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TAS2R31 taste receptor, type 2, member 31
TBK1 TANK-binding kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
TERT telomerase reverse transcriptase
TGFBR1 transforming growth factor, beta receptor 1
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP1 topoisomerase (DNA) I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTR transthyretin
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
TYR tyrosinase
TYRO3 TYRO3 protein tyrosine kinase
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UPP1 uridine phosphorylase 1
VCP valosin containing protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WEE1 WEE1 G2 checkpoint kinase
XDH xanthine dehydrogenase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa