| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | promyelocytic leukemia|The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5371) |
| External Link | https://ncbi.nlm.nih.gov/gene/5371 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the PML gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.0200049 |
| PLK1 | polo-like kinase 1 | 0.016279 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0133928 |
| PRR7 | proline rich 7 (synaptic) | 0.0132695 |
| DNTT | DNA nucleotidylexotransferase | 0.0123284 |
| S100A8 | S100 calcium binding protein A8 | 0.011746 |
| FABP7 | fatty acid binding protein 7, brain | 0.01173 |
| ADI1 | acireductone dioxygenase 1 | 0.0108484 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.0105971 |
| CLDN8 | claudin 8 | 0.0105754 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0105663 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.0104418 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0103877 |
| TXNDC9 | thioredoxin domain containing 9 | 0.0103821 |
| CDCA4 | cell division cycle associated 4 | 0.0103398 |
| VAMP8 | vesicle-associated membrane protein 8 | 0.0103247 |
| RAB25 | RAB25, member RAS oncogene family | 0.010234 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0101063 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0100765 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.0100652 |
| CETN2 | centrin, EF-hand protein, 2 | 0.0100355 |
| HOXC6 | homeobox C6 | 0.0100017 |
| COG2 | component of oligomeric golgi complex 2 | 0.00997034 |
| YBX3 | Y box binding protein 3 | 0.00989249 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00988424 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00970179 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00955788 |
| RGS10 | regulator of G-protein signaling 10 | 0.00952785 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00942736 |
| SDC1 | syndecan 1 | 0.00937191 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00921244 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00916117 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00914422 |
| CD1E | CD1e molecule | 0.0091219 |
| DAZAP2 | DAZ associated protein 2 | 0.0090922 |
| MUC4 | mucin 4, cell surface associated | 0.00901241 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00891101 |
| LTA4H | leukotriene A4 hydrolase | 0.00873638 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00861031 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00845287 |
| FST | follistatin | 0.00843082 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00839055 |
| CD9 | CD9 molecule | 0.00839027 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00838543 |
| POSTN | periostin, osteoblast specific factor | 0.00837413 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00835593 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00834383 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.00811318 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00808522 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00805316 |
| TFDP1 | transcription factor Dp-1 | 0.00805055 |
| RNF14 | ring finger protein 14 | 0.00796844 |
| XPO7 | exportin 7 | 0.0079652 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00793112 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.0078566 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00782711 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00781329 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00779678 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00777445 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00775045 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00774103 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00770005 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00766242 |
| TPM4 | tropomyosin 4 | 0.0076594 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00758822 |
| TRAM1 | translocation associated membrane protein 1 | 0.00751365 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00751357 |
| RAB4A | RAB4A, member RAS oncogene family | 0.0075033 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00750025 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein | 0.00742544 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00740448 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00739066 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.00738256 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00736417 |
| DAPK1 | death-associated protein kinase 1 | 0.00736362 |
| SC5D | sterol-C5-desaturase | 0.00735381 |
| IRX5 | iroquois homeobox 5 | 0.007339 |
| NDNF | neuron-derived neurotrophic factor | 0.00733574 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00728437 |
| CRIP2 | cysteine-rich protein 2 | 0.00726108 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00724055 |
| COPS7A | COP9 signalosome subunit 7A | 0.00722675 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00719149 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00716398 |
| SMAGP | small cell adhesion glycoprotein | 0.00715812 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.007138 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00711312 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00708842 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00708098 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00707843 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00705775 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00705774 |
| SET | SET nuclear proto-oncogene | 0.00704229 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00701039 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 0.0070077 |
| SIRT3 | sirtuin 3 | 0.00699021 |
| E2F2 | E2F transcription factor 2 | 0.00698889 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 0.00697513 |
| FASN | fatty acid synthase | 0.00695263 |
| ATG5 | autophagy related 5 | 0.00694867 |
| MMP12 | matrix metallopeptidase 12 | 0.00689827 |
| LST1 | leukocyte specific transcript 1 | 0.00689653 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.00687671 |
| H1-10 | H1.10 linker histone | 0.00686907 |
| NFYB | nuclear transcription factor Y, beta | 0.00686054 |
| CDC42 | cell division cycle 42 | 0.00684659 |
| IFT57 | intraflagellar transport 57 | 0.00683926 |
| CDH16 | cadherin 16, KSP-cadherin | 0.00681133 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00680627 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00676547 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00674726 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.00673075 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 0.00672663 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00671288 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.00670979 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.00668984 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00663504 |
| GTPBP8 | GTP-binding protein 8 (putative) | 0.00661508 |
| SPA17 | sperm autoantigenic protein 17 | 0.00661337 |
| CD1B | CD1b molecule | 0.00658907 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00657645 |
| YIPF5 | Yip1 domain family, member 5 | 0.0065676 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00655715 |
| EAF2 | ELL associated factor 2 | 0.00655434 |
| SELENOT | selenoprotein T | 0.00653543 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.00652844 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | 0.00652417 |
| MDFIC | MyoD family inhibitor domain containing | 0.00652131 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 0.0065098 |
| NPR3 | natriuretic peptide receptor 3 | 0.00650548 |
| RDX | radixin | 0.00649436 |
| ARRB2 | arrestin, beta 2 | 0.0064605 |
| PLIN3 | perilipin 3 | 0.00645205 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00642295 |
| SFTPA2 | surfactant protein A2 | 0.00640677 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00640511 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.00640373 |
| CCNA2 | cyclin A2 | 0.00637778 |
| OIP5 | Opa interacting protein 5 | 0.00636329 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00635356 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00634501 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.00633505 |
| CTSS | cathepsin S | 0.00631942 |
| SRR | serine racemase | 0.00629621 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00627897 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | 0.00627055 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00626417 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.00623202 |
| SRP72 | signal recognition particle 72kDa | 0.00622397 |
| RAB21 | RAB21, member RAS oncogene family | 0.00619585 |
| TSPAN1 | tetraspanin 1 | 0.00617984 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 | 0.00617959 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00617775 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00617659 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00614235 |
| STOM | stomatin | 0.00614155 |
| MREG | melanoregulin | 0.00613528 |
| SOSTDC1 | sclerostin domain containing 1 | 0.00613051 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00612877 |
| H2AFV | H2A histone family, member V | 0.00612087 |
| SFTPB | surfactant protein B | 0.00611407 |
| PIMREG | PICALM interacting mitotic regulator | 0.006087 |
| DNASE2 | deoxyribonuclease II, lysosomal | 0.00608408 |
| TRMT5 | tRNA methyltransferase 5 | 0.00607618 |
| SV2A | synaptic vesicle glycoprotein 2A | 0.00607588 |
| CTSK | cathepsin K | 0.00607118 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00605453 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 | 0.00605416 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00601284 |
| DALRD3 | DALR anticodon binding domain containing 3 | 0.00600975 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00600904 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00599631 |
| CD99 | CD99 molecule | 0.00599281 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00597813 |
| IL2RG | interleukin 2 receptor, gamma | 0.00597735 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00597492 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00597215 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.00596812 |
| JUND | jun D proto-oncogene | 0.00595953 |
| ITM2C | integral membrane protein 2C | 0.00595903 |
| FDX1 | ferredoxin 1 | 0.00595004 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 0.00593974 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00593644 |
| FTO | fat mass and obesity associated | 0.00592951 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00592345 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 | 0.00592339 |
| DHCR24 | 24-dehydrocholesterol reductase | 0.00592067 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 0.0058989 |
| CAPRIN1 | cell cycle associated protein 1 | 0.00588995 |
| MMP7 | matrix metallopeptidase 7 | 0.00588798 |
| GLE1 | GLE1 RNA export mediator | 0.00587684 |
| TAGLN2 | transgelin 2 | 0.00587504 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00587267 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 0.00586311 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 0.00586113 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00586048 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00585776 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.0058553 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.00585003 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00584536 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00584395 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00583651 |
| FKBP5 | FK506 binding protein 5 | 0.00583104 |
| GRAMD1C | GRAM domain containing 1C | 0.0058153 |
| SCN2A | sodium channel, voltage gated, type II alpha subunit | 0.00579075 |
| RCAN1 | regulator of calcineurin 1 | 0.00578515 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00577352 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.00577297 |
| HMGB1 | high mobility group box 1 | 0.00577054 |
| INSIG1 | insulin induced gene 1 | 0.00576808 |
| KRT15 | keratin 15, type I | 0.00575695 |
| ANXA6 | annexin A6 | 0.00575601 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.0057442 |
| EPCAM | epithelial cell adhesion molecule | 0.00573476 |
| ASRGL1 | asparaginase like 1 | 0.00573081 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00572706 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | 0.00572142 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00571632 |
| MNS1 | meiosis-specific nuclear structural 1 | 0.00571115 |
| GLUL | glutamate-ammonia ligase | 0.00570228 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00570113 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0056992 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00569746 |
| TMEM231 | transmembrane protein 231 | 0.00569519 |
| PRDX3 | peroxiredoxin 3 | 0.00568629 |
| IER3IP1 | immediate early response 3 interacting protein 1 | 0.00568499 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00568321 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00567879 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00566275 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00566217 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00565245 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00565102 |
| BLNK | B-cell linker | 0.00565 |
| RAB14 | RAB14, member RAS oncogene family | 0.00564764 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 0.00564452 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.00564089 |
| CCNC | cyclin C | 0.00564035 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00562973 |
| NME5 | NME/NM23 family member 5 | 0.00562423 |
| AMACR | alpha-methylacyl-CoA racemase | 0.0056237 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00560916 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) | 0.00560697 |
| COL10A1 | collagen, type X, alpha 1 | 0.00559977 |
| F12 | coagulation factor XII (Hageman factor) | 0.00559733 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 | 0.00557373 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.00556499 |
| LSM1 | LSM1, U6 small nuclear RNA associated | 0.00556417 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00555359 |
| CLEC10A | C-type lectin domain family 10, member A | 0.00555285 |
| METTL7A | methyltransferase like 7A | 0.00555243 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | -0.0206107 |
| S100P | S100 calcium binding protein P | -0.0183782 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0182701 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0158955 |
| MX1 | MX dynamin-like GTPase 1 | -0.015751 |
| IFI44L | interferon-induced protein 44-like | -0.0151742 |
| STK10 | serine/threonine kinase 10 | -0.0149225 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0148608 |
| STC2 | stanniocalcin 2 | -0.0145971 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0145804 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0143706 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0134857 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | -0.0132103 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0130199 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0129236 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0127702 |
| G0S2 | G0/G1 switch 2 | -0.0123681 |
| PDGFD | platelet derived growth factor D | -0.0123229 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0122176 |
| CFB | complement factor B | -0.0119455 |
| MLPH | melanophilin | -0.0116763 |
| DST | dystonin | -0.0113929 |
| TBX3 | T-box 3 | -0.0113801 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0113253 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0112458 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0111228 |
| NID2 | nidogen 2 (osteonidogen) | -0.0111114 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0111011 |
| HSPB8 | heat shock 22kDa protein 8 | -0.0110772 |
| RGS16 | regulator of G-protein signaling 16 | -0.0110699 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.010995 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.0108892 |
| NEFH | neurofilament, heavy polypeptide | -0.0108846 |
| TTN | titin | -0.0108282 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.0107611 |
| THBS4 | thrombospondin 4 | -0.0107495 |
| ADIRF | adipogenesis regulatory factor | -0.0107269 |
| MX2 | MX dynamin-like GTPase 2 | -0.0107246 |
| PDZD2 | PDZ domain containing 2 | -0.0107017 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0106786 |
| RTN2 | reticulon 2 | -0.0106635 |
| ASS1 | argininosuccinate synthase 1 | -0.0106332 |
| MGLL | monoglyceride lipase | -0.0106153 |
| OGN | osteoglycin | -0.0105672 |
| PLIN2 | perilipin 2 | -0.0105503 |
| COL5A2 | collagen, type V, alpha 2 | -0.0105479 |
| HMOX1 | heme oxygenase 1 | -0.0104974 |
| IRS2 | insulin receptor substrate 2 | -0.0104721 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0104606 |
| XAF1 | XIAP associated factor 1 | -0.010423 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0103757 |
| PLCB4 | phospholipase C, beta 4 | -0.0103482 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0103435 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0102865 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0102366 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.0102164 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0102159 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.0101945 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0100486 |
| CHMP4A | charged multivesicular body protein 4A | -0.0100252 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.0100232 |
| RET | ret proto-oncogene | -0.0100187 |
| IRF9 | interferon regulatory factor 9 | -0.0100109 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00995682 |
| RGS5 | regulator of G-protein signaling 5 | -0.00994446 |
| TAC1 | tachykinin, precursor 1 | -0.00993178 |
| VWF | von Willebrand factor | -0.0098833 |
| SNAI2 | snail family zinc finger 2 | -0.00987749 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00981716 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.00971891 |
| ZIC1 | Zic family member 1 | -0.00965868 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00963651 |
| PEG3 | paternally expressed 3 | -0.00961705 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | -0.00960965 |
| IL6 | interleukin 6 | -0.00952731 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00952008 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.00950032 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00943671 |
| RELN | reelin | -0.00939944 |
| JUNB | jun B proto-oncogene | -0.00934786 |
| KLHL41 | kelch-like family member 41 | -0.00933976 |
| CKM | creatine kinase, muscle | -0.0093022 |
| LAMB1 | laminin, beta 1 | -0.00928401 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.00927759 |
| PTCH1 | patched 1 | -0.00926384 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00926222 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00925453 |
| MIR22HG | MIR22 host gene | -0.00917087 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00917029 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00913106 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00903523 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.00899762 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00899251 |
| CLU | clusterin | -0.00897994 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00895779 |
| OLFML2A | olfactomedin-like 2A | -0.00890176 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.00885762 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00879195 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00876452 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.00871933 |
| FMOD | fibromodulin | -0.00871873 |
| PLS3 | plastin 3 | -0.00871668 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00870144 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00868936 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00867497 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00861778 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00854676 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00853471 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00853314 |
| AUTS2 | autism susceptibility candidate 2 | -0.00847602 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00845658 |
| MYBPC1 | myosin binding protein C, slow type | -0.00843106 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00837818 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00835866 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00834508 |
| PCOLCE | procollagen C-endopeptidase enhancer | -0.00833074 |
| MT1M | metallothionein 1M | -0.00832475 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00822806 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | -0.0082163 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00818173 |
| ANK2 | ankyrin 2, neuronal | -0.00818134 |
| CAPN6 | calpain 6 | -0.00817172 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00816556 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00816438 |
| COCH | cochlin | -0.00815981 |
| KRT23 | keratin 23, type I | -0.00815125 |
| TNS3 | tensin 3 | -0.00814948 |
| ACKR3 | atypical chemokine receptor 3 | -0.00814585 |
| MMP19 | matrix metallopeptidase 19 | -0.00814294 |
| CD69 | CD69 molecule | -0.00812922 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00810855 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | -0.00807576 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00807154 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00805489 |
| EPHA2 | EPH receptor A2 | -0.0080447 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00803653 |
| SMPX | small muscle protein, X-linked | -0.00803599 |
| TPCN1 | two pore segment channel 1 | -0.00801673 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00798319 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00795753 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00794891 |
| VEGFA | vascular endothelial growth factor A | -0.00793619 |
| ITM2A | integral membrane protein 2A | -0.00793396 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00792377 |
| LOXL2 | lysyl oxidase-like 2 | -0.0079058 |
| ITPKB | inositol-trisphosphate 3-kinase B | -0.00789241 |
| KIAA1109 | KIAA1109 | -0.00787142 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00786369 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.00785358 |
| EGR1 | early growth response 1 | -0.00785184 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00781699 |
| IER5 | immediate early response 5 | -0.00781645 |
| TUBB2B | tubulin, beta 2B class IIb | -0.007789 |
| AGR2 | anterior gradient 2 | -0.00777917 |
| INHBE | inhibin, beta E | -0.00776534 |
| GDF15 | growth differentiation factor 15 | -0.00776445 |
| FZD10 | frizzled class receptor 10 | -0.00776214 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00775614 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00775545 |
| MTCL1 | microtubule crosslinking factor 1 | -0.00774319 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00772008 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.00771757 |
| SHOX2 | short stature homeobox 2 | -0.00770699 |
| TRIB3 | tribbles pseudokinase 3 | -0.00770238 |
| PDGFRL | platelet-derived growth factor receptor-like | -0.00769922 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0076885 |
| IL1R1 | interleukin 1 receptor, type I | -0.00768606 |
| CST7 | cystatin F (leukocystatin) | -0.00766064 |
| LRRC17 | leucine rich repeat containing 17 | -0.0076572 |
| RRBP1 | ribosome binding protein 1 | -0.00765616 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0076477 |
| JMJD6 | jumonji domain containing 6 | -0.00761974 |
| SH3BP4 | SH3-domain binding protein 4 | -0.0076186 |
| CEP170 | centrosomal protein 170kDa | -0.00761789 |
| CPE | carboxypeptidase E | -0.00760983 |
| FOXF1 | forkhead box F1 | -0.00760353 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00759896 |
| PLK2 | polo-like kinase 2 | -0.00759047 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00758965 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0075844 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0075767 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00753685 |
| EPHB2 | EPH receptor B2 | -0.00751732 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00750261 |
| PCDH17 | protocadherin 17 | -0.00749357 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00746912 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00745209 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.00743189 |
| GTPBP2 | GTP binding protein 2 | -0.00742627 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | -0.00742244 |
| FGL1 | fibrinogen-like 1 | -0.00736198 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -0.00733766 |
| C5AR1 | complement component 5a receptor 1 | -0.00732441 |
| IL1RN | interleukin 1 receptor antagonist | -0.00731554 |
| STMN2 | stathmin 2 | -0.00731293 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00730347 |
| CD83 | CD83 molecule | -0.00729958 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00728611 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00728412 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | -0.007272 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -0.00727155 |
| ENO3 | enolase 3 (beta, muscle) | -0.00726631 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00726497 |
| SFN | stratifin | -0.0072441 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00723386 |
| ZNF532 | zinc finger protein 532 | -0.0072279 |
| MATN2 | matrilin 2 | -0.00721174 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00720378 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00719015 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00713718 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00713206 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.0071202 |
| PEG10 | paternally expressed 10 | -0.00711576 |
| PDE10A | phosphodiesterase 10A | -0.00711307 |
| LDB3 | LIM domain binding 3 | -0.00710542 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.00709155 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00706552 |
| DCHS1 | dachsous cadherin-related 1 | -0.00706299 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | -0.00705941 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00704855 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00704792 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00703608 |
| TESC | tescalcin | -0.00701478 |
| TNNC2 | troponin C type 2 (fast) | -0.00700892 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00700863 |
| ANXA3 | annexin A3 | -0.00700226 |
| AADAC | arylacetamide deacetylase | -0.00698878 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.00696991 |
| TUBA4A | tubulin, alpha 4a | -0.00696132 |
| BEX1 | brain expressed, X-linked 1 | -0.00694406 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00694376 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00693801 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00693663 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00693437 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00692394 |
| RGS1 | regulator of G-protein signaling 1 | -0.00690655 |
| ATF4 | activating transcription factor 4 | -0.00689545 |
| CTSA | cathepsin A | -0.00689281 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00688721 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00687516 |
| STK39 | serine threonine kinase 39 | -0.00686895 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00686315 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00684897 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00683146 |
| CHGB | chromogranin B | -0.0068154 |
| ATP9A | ATPase, class II, type 9A | -0.00681497 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00680779 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.00680352 |
| KEAP1 | kelch-like ECH-associated protein 1 | -0.00679784 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00679535 |
