| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | purine nucleoside phosphorylase|This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4860) |
| External Link | https://ncbi.nlm.nih.gov/gene/4860 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the PNP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.00714572 |
| LTF | lactotransferrin | 0.00683186 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.0067953 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0064889 |
| PCNA | proliferating cell nuclear antigen | 0.00610973 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00608505 |
| MMP9 | matrix metallopeptidase 9 | 0.00597665 |
| AUTS2 | autism susceptibility candidate 2 | 0.00594999 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00585616 |
| SIK1 | salt-inducible kinase 1 | 0.0053391 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00522892 |
| FERMT1 | fermitin family member 1 | 0.00488555 |
| ATP11B | ATPase, class VI, type 11B | 0.00461809 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00454683 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.00450042 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.00449056 |
| FBXO21 | F-box protein 21 | 0.00446974 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00446183 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0044229 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.00437771 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.00436922 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.00431529 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00431117 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00428997 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00427243 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00423019 |
| CST7 | cystatin F (leukocystatin) | 0.00422685 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00414835 |
| CCNA2 | cyclin A2 | 0.0041438 |
| NRN1 | neuritin 1 | 0.00410008 |
| POU2AF1 | POU class 2 associating factor 1 | 0.0040807 |
| BANF1 | barrier to autointegration factor 1 | 0.00406963 |
| NKX3-1 | NK3 homeobox 1 | 0.00405373 |
| CD8A | CD8a molecule | 0.00402767 |
| MEIS2 | Meis homeobox 2 | 0.00402741 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00400675 |
| PLK1 | polo-like kinase 1 | 0.00400102 |
| CCP110 | centriolar coiled coil protein 110kDa | 0.00399012 |
| TPM2 | tropomyosin 2 (beta) | 0.00396919 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00395863 |
| CCNB2 | cyclin B2 | 0.003956 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00395579 |
| INSM1 | insulinoma-associated 1 | 0.00394494 |
| IL7R | interleukin 7 receptor | 0.00394346 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00393406 |
| MAGEA3 | melanoma antigen family A3 | 0.00393237 |
| APMAP | adipocyte plasma membrane associated protein | 0.00392063 |
| SPAG1 | sperm associated antigen 1 | 0.00390536 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00385116 |
| TSPAN13 | tetraspanin 13 | 0.00384769 |
| EHF | ets homologous factor | 0.00383434 |
| COPS7A | COP9 signalosome subunit 7A | 0.00380772 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.00375883 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00373875 |
| CLCA1 | chloride channel accessory 1 | 0.00373563 |
| IPO5 | importin 5 | 0.00371644 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.0037108 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00369748 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00369592 |
| ANXA6 | annexin A6 | 0.00369061 |
| DBF4 | DBF4 zinc finger | 0.00367017 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.00365821 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.0036156 |
| PSRC1 | proline/serine-rich coiled-coil 1 | 0.00360588 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.00357736 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00356052 |
| ABHD6 | abhydrolase domain containing 6 | 0.0035593 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.00354871 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00352341 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00351424 |
| PAX5 | paired box 5 | 0.00349621 |
| MMD | monocyte to macrophage differentiation-associated | 0.00349394 |
| NEK2 | NIMA-related kinase 2 | 0.00347952 |
| TARDBP | TAR DNA binding protein | 0.00347537 |
| PRELID3B | PRELI domain containing 3B | 0.00347409 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00347302 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00346912 |
| TPM4 | tropomyosin 4 | 0.00346286 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.00346016 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00345986 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00345967 |
| FOXG1 | forkhead box G1 | 0.00344314 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00344187 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.00343646 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.0034325 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00343028 |
| SPEN | spen family transcriptional repressor | 0.0034244 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00341487 |
| KLRC3 | killer cell lectin-like receptor subfamily C, member 3 | 0.00339621 |
| OLFM4 | olfactomedin 4 | 0.00339463 |
| NKG7 | natural killer cell granule protein 7 | 0.00335229 |
| IL2RG | interleukin 2 receptor, gamma | 0.00331047 |
| SACS | sacsin molecular chaperone | 0.00330675 |
| BTG3 | BTG family, member 3 | 0.00330285 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00329687 |
| IL2RB | interleukin 2 receptor, beta | 0.00327732 |
| MKI67 | marker of proliferation Ki-67 | 0.00327038 |
| FANCL | Fanconi anemia, complementation group L | 0.00326586 |
| RPIA | ribose 5-phosphate isomerase A | 0.00325718 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00325526 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00323346 |
| SRI | sorcin | 0.00321303 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00321235 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00320671 |
| ACTL6A | actin-like 6A | 0.00320192 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00318669 |
| HPF1 | histone PARylation factor 1 | 0.00318598 |
| GAS1 | growth arrest-specific 1 | 0.00318414 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00317555 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00315972 |
| TRIP13 | thyroid hormone receptor interactor 13 | 0.00315429 |
| CD19 | CD19 molecule | 0.00315309 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00315251 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00314656 |
| HMGB2 | high mobility group box 2 | 0.00313515 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00313216 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00313213 |
| C1QB | complement component 1, q subcomponent, B chain | 0.0031291 |
| TASOR | transcription activation suppressor | 0.00312528 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0030992 |
| GTPBP4 | GTP binding protein 4 | 0.00309818 |
| PRF1 | perforin 1 (pore forming protein) | 0.00308728 |
| LMNB1 | lamin B1 | 0.00308525 |
| ADA | adenosine deaminase | 0.00307113 |
| ODC1 | ornithine decarboxylase 1 | 0.00306608 |
| RBM34 | RNA binding motif protein 34 | 0.00306587 |
| XIC | X chromosome inactivation center | 0.00306311 |
| WT1 | Wilms tumor 1 | 0.00306245 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00304051 |
| IL7 | interleukin 7 | 0.00303247 |
| JMJD6 | jumonji domain containing 6 | 0.00302218 |
| MAGEA12 | melanoma antigen family A12 | 0.00301823 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00301695 |
| KLHL2 | kelch-like family member 2 | 0.00300171 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.00299737 |
| MMP12 | matrix metallopeptidase 12 | 0.0029849 |
| CLU | clusterin | 0.00298455 |
| DDHD2 | DDHD domain containing 2 | 0.00298348 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00297765 |
| TRMT5 | tRNA methyltransferase 5 | 0.00295884 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0029556 |
| THYN1 | thymocyte nuclear protein 1 | 0.00295368 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.00294912 |
| KLK6 | kallikrein-related peptidase 6 | 0.00294187 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00292473 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00291417 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.00289854 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00289714 |
| CNTRL | centriolin | 0.00288965 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00288384 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.00288366 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00288156 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00288121 |
| FBXW2 | F-box and WD repeat domain containing 2 | 0.00288073 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | 0.00287409 |
| CCNE2 | cyclin E2 | 0.00287281 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00286871 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.0028677 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.00286652 |
| FCGBP | Fc fragment of IgG binding protein | 0.00286368 |
| TYMS | thymidylate synthetase | 0.00285788 |
| CD2 | CD2 molecule | 0.00285705 |
| TIPRL | TOR signaling pathway regulator | 0.00283917 |
| CANT1 | calcium activated nucleotidase 1 | 0.00283914 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0028391 |
| TMEM106C | transmembrane protein 106C | 0.002839 |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.00282916 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.00282081 |
| C3 | complement component 3 | 0.00281258 |
| CTPS1 | CTP synthase 1 | 0.00280879 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00280561 |
| FOXM1 | forkhead box M1 | 0.00280555 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00280251 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.00279266 |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.00278612 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.00276948 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.00276592 |
| CBX5 | chromobox homolog 5 | 0.00276318 |
| KIF1B | kinesin family member 1B | 0.00275992 |
| KIF11 | kinesin family member 11 | 0.00275846 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00275511 |
| SHTN1 | shootin 1 | 0.00275155 |
| TNC | tenascin C | 0.00274922 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00274773 |
| CLCA2 | chloride channel accessory 2 | 0.00274614 |
| OTULINL | OTU deubiquitinase with linear linkage specificity like | 0.00274569 |
| DPY19L2P2 | DPY19L2 pseudogene 2 | 0.00274163 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.00273593 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00273574 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.0027337 |
| CEP55 | centrosomal protein 55kDa | 0.00273275 |
| TRAF3 | TNF receptor-associated factor 3 | 0.00273021 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0027203 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00272004 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 | 0.00271756 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | 0.00271667 |
| SETD6 | SET domain containing 6 | 0.00271574 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein | 0.00270838 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00270597 |
| M6PR | mannose-6-phosphate receptor (cation dependent) | 0.00269964 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00269808 |
| CDCA3 | cell division cycle associated 3 | 0.00269757 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00269527 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00268715 |
| SSRP1 | structure specific recognition protein 1 | 0.00268436 |
| TRIM14 | tripartite motif containing 14 | 0.00268065 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | 0.00267937 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00267814 |
| LMNB2 | lamin B2 | 0.00267785 |
| FABP1 | fatty acid binding protein 1, liver | 0.00267606 |
| KRT15 | keratin 15, type I | 0.00267598 |
| LCN2 | lipocalin 2 | 0.00267577 |
| FBXO5 | F-box protein 5 | 0.00267338 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 0.00267215 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00266798 |
| TBCD | tubulin folding cofactor D | 0.00266497 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00265384 |
| ATR | ATR serine/threonine kinase | 0.0026504 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase | 0.00264993 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00263867 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.00263787 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.00263686 |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.0026365 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 0.00263027 |
| IL20RA | interleukin 20 receptor, alpha | 0.00262969 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | 0.00262759 |
| RHOH | ras homolog family member H | 0.00261905 |
| TULP4 | tubby like protein 4 | 0.00261099 |
| MTMR1 | myotubularin related protein 1 | 0.00260861 |
| KIF18B | kinesin family member 18B | 0.00260791 |
| PASK | PAS domain containing serine/threonine kinase | 0.00260488 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | 0.00259662 |
| H2AX | H2A.X variant histone | 0.00259597 |
| CLDN8 | claudin 8 | 0.00259464 |
| SPC25 | SPC25, NDC80 kinetochore complex component | 0.0025932 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00259316 |
| CEP43 | centrosomal protein 43 | 0.00258562 |
| TWF1 | twinfilin actin binding protein 1 | 0.00257192 |
| RANBP1 | RAN binding protein 1 | 0.00257025 |
| DHFR | dihydrofolate reductase | 0.00256487 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00256298 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00255651 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00255586 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00255504 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.00255234 |
| MED14 | mediator complex subunit 14 | 0.0025522 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 0.00255204 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.00255189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PNP | purine nucleoside phosphorylase | -0.00954545 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00720742 |
| ASS1 | argininosuccinate synthase 1 | -0.00683776 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00667068 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00643614 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00613023 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00609536 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00594007 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00590583 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00587554 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0058598 |
| MT1E | metallothionein 1E | -0.00580793 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00564482 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00562589 |
| RGS4 | regulator of G-protein signaling 4 | -0.0055668 |
| OLFML3 | olfactomedin-like 3 | -0.00555225 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00552428 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00548074 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00544827 |
| STC1 | stanniocalcin 1 | -0.00523806 |
| ADIRF | adipogenesis regulatory factor | -0.00522071 |
| NID1 | nidogen 1 | -0.00515347 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00513358 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00502488 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00497932 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00493637 |
| NEFM | neurofilament, medium polypeptide | -0.00488631 |
| NID2 | nidogen 2 (osteonidogen) | -0.00479285 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0047872 |
| UPP1 | uridine phosphorylase 1 | -0.00478638 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00478067 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00477642 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.00476239 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00468345 |
| POSTN | periostin, osteoblast specific factor | -0.00467934 |
| MAL | mal, T-cell differentiation protein | -0.00467131 |
| MXRA5 | matrix-remodelling associated 5 | -0.00464569 |
| LRRC17 | leucine rich repeat containing 17 | -0.00462965 |
| BMP4 | bone morphogenetic protein 4 | -0.00462369 |
| PLAU | plasminogen activator, urokinase | -0.00461017 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00456618 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00456169 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00446669 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0044497 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00444835 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00444612 |
| TMEM176B | transmembrane protein 176B | -0.00444455 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00443897 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00442528 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | -0.00440997 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00440421 |
| ASPN | asporin | -0.00435969 |
| ARG2 | arginase 2 | -0.00435089 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.0042885 |
| DEFB1 | defensin, beta 1 | -0.00425422 |
| KDR | kinase insert domain receptor | -0.00421776 |
| MX1 | MX dynamin-like GTPase 1 | -0.00420507 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00419933 |
| CD93 | CD93 molecule | -0.00418951 |
| HSPA2 | heat shock 70kDa protein 2 | -0.00418503 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.00417912 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00415569 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00414188 |
| TM7SF2 | transmembrane 7 superfamily member 2 | -0.00412367 |
| MATN2 | matrilin 2 | -0.00412308 |
| OLFML2A | olfactomedin-like 2A | -0.00410661 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00410488 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.0041038 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 | -0.00410256 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00405396 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00403048 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00402535 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00400195 |
| ICAM2 | intercellular adhesion molecule 2 | -0.00400185 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.00399037 |
| CTTN | cortactin | -0.00398837 |
| ZNF91 | zinc finger protein 91 | -0.00396467 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00394145 |
| IFI44L | interferon-induced protein 44-like | -0.00392638 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00392317 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00391565 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.00391349 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00390215 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00389605 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00387103 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.003836 |
| DPP4 | dipeptidyl-peptidase 4 | -0.0038322 |
| MTF2 | metal response element binding transcription factor 2 | -0.00382668 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00380519 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00378098 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00377786 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00377264 |
| DCN | decorin | -0.00374613 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00373696 |
| ANK2 | ankyrin 2, neuronal | -0.00372934 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | -0.00371162 |
| PLS3 | plastin 3 | -0.00370417 |
| RTN2 | reticulon 2 | -0.00370007 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00368453 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00368163 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.00368137 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00365741 |
| APOD | apolipoprotein D | -0.00365314 |
| PLIN2 | perilipin 2 | -0.00365172 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa | -0.0036472 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | -0.00364219 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00363392 |
| GNAS | GNAS complex locus | -0.00362672 |
| SIX1 | SIX homeobox 1 | -0.00361764 |
| CRYAB | crystallin, alpha B | -0.00361697 |
| CTSK | cathepsin K | -0.00361513 |
| NOX4 | NADPH oxidase 4 | -0.00358823 |
| PDGFC | platelet derived growth factor C | -0.00358028 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00355692 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00355505 |
| FLT1 | fms-related tyrosine kinase 1 | -0.00354687 |
| HNMT | histamine N-methyltransferase | -0.00353579 |
| CA2 | carbonic anhydrase II | -0.00353327 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.0035268 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -0.0035245 |
| VCAN | versican | -0.00352258 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00352166 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00351978 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00351481 |
| RRAGC | Ras-related GTP binding C | -0.00351137 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00348339 |
| COCH | cochlin | -0.0034796 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00347864 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.00347231 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00345841 |
| GMFG | glia maturation factor, gamma | -0.00344434 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00343153 |
| CCNG2 | cyclin G2 | -0.00342966 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.00342736 |
| PLK2 | polo-like kinase 2 | -0.00342387 |
| TRIP6 | thyroid hormone receptor interactor 6 | -0.00341929 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | -0.00341916 |
| CLDN10 | claudin 10 | -0.00341532 |
| CALB1 | calbindin 1, 28kDa | -0.0034117 |
| RELN | reelin | -0.00340949 |
| IRF9 | interferon regulatory factor 9 | -0.0034028 |
| MT1F | metallothionein 1F | -0.00339713 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00339664 |
| MMP11 | matrix metallopeptidase 11 | -0.00339243 |
| EMCN | endomucin | -0.00338866 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00338551 |
| RNASET2 | ribonuclease T2 | -0.00338265 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00338022 |
| PLAT | plasminogen activator, tissue | -0.00336776 |
| WBP5 | WW domain binding protein 5 | -0.00336482 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00336244 |
| TSPYL5 | TSPY-like 5 | -0.0033516 |
| DAPK1 | death-associated protein kinase 1 | -0.00333849 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00333422 |
| FZD6 | frizzled class receptor 6 | -0.00333112 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00332589 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | -0.00331479 |
| PNMA1 | paraneoplastic Ma antigen 1 | -0.00330051 |
| SV2B | synaptic vesicle glycoprotein 2B | -0.00329666 |
| PDZK1 | PDZ domain containing 1 | -0.0032945 |
| PRDX2 | peroxiredoxin 2 | -0.003292 |
| NXN | nucleoredoxin | -0.00328843 |
| FADD | Fas (TNFRSF6)-associated via death domain | -0.0032833 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00327801 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.00327259 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | -0.00326944 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00326787 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.00326192 |
| GCH1 | GTP cyclohydrolase 1 | -0.00325454 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00325261 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00324712 |
| RGS5 | regulator of G-protein signaling 5 | -0.0032429 |
| S100A2 | S100 calcium binding protein A2 | -0.00324285 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00323576 |
| RPS27L | ribosomal protein S27-like | -0.00323403 |
| PLD3 | phospholipase D family, member 3 | -0.00322051 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00321177 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00321019 |
| MITF | microphthalmia-associated transcription factor | -0.00320326 |
| GNS | glucosamine (N-acetyl)-6-sulfatase | -0.00319766 |
| MXRA8 | matrix-remodelling associated 8 | -0.00319172 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00319157 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00317498 |
| ASPA | aspartoacylase | -0.00315899 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.00315848 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.0031494 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00314261 |
| S100A10 | S100 calcium binding protein A10 | -0.00314133 |
| MX2 | MX dynamin-like GTPase 2 | -0.00313973 |
| CAST | calpastatin | -0.00313656 |
| LOC283683 | uncharacterized LOC283683 | -0.0031081 |
| GATA2 | GATA binding protein 2 | -0.00310756 |
| GSTZ1 | glutathione S-transferase zeta 1 | -0.00310515 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.00308606 |
| HMOX1 | heme oxygenase 1 | -0.00308249 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00308172 |
| DUSP4 | dual specificity phosphatase 4 | -0.00307449 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -0.00306937 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | -0.0030634 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.0030575 |
| CTBS | chitobiase, di-N-acetyl- | -0.00305026 |
| MT1H | metallothionein 1H | -0.00304829 |
| HBP1 | HMG-box transcription factor 1 | -0.00304157 |
| FADS3 | fatty acid desaturase 3 | -0.00303915 |
| FGB | fibrinogen beta chain | -0.00303318 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.00303257 |
| VSNL1 | visinin-like 1 | -0.00303174 |
| PLA1A | phospholipase A1 member A | -0.00302755 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | -0.00301929 |
| CFD | complement factor D (adipsin) | -0.0030134 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -0.00301214 |
| SFRP4 | secreted frizzled-related protein 4 | -0.00301206 |
| SPP1 | secreted phosphoprotein 1 | -0.00300998 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00300895 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C | -0.00300875 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00300436 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00300258 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00300039 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.00299579 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.0029754 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00297514 |
| SYT1 | synaptotagmin I | -0.00296954 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00296705 |
| ZNF43 | zinc finger protein 43 | -0.00296537 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0029611 |
| MRPL57 | mitochondrial ribosomal protein L57 | -0.00295818 |
| CNN3 | calponin 3, acidic | -0.0029554 |
| SST | somatostatin | -0.00295129 |
| TMEM8A | transmembrane protein 8A | -0.00295099 |
| BCL2L1 | BCL2-like 1 | -0.00293352 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0029236 |
| TRIM22 | tripartite motif containing 22 | -0.00291925 |
| GPX7 | glutathione peroxidase 7 | -0.00291623 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.00290623 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00290494 |
| SCAND1 | SCAN domain containing 1 | -0.00290281 |
| FGA | fibrinogen alpha chain | -0.00289925 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | -0.00288616 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00288119 |
| IL17RB | interleukin 17 receptor B | -0.0028792 |
| PDLIM4 | PDZ and LIM domain 4 | -0.0028751 |
| RAB31 | RAB31, member RAS oncogene family | -0.00287469 |
| CALCRL | calcitonin receptor-like | -0.00287408 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.0028728 |
| HBD | hemoglobin, delta | -0.0028727 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00287119 |
| GPR137B | G protein-coupled receptor 137B | -0.00287056 |
| CTH | cystathionine gamma-lyase | -0.002869 |
| CST6 | cystatin E/M | -0.00286605 |
