PNU-0230031-3629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the PNU-0230031-3629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAMDEC1 ADAM-like, decysin 1
ALPL alkaline phosphatase, liver/bone/kidney
APOC1 apolipoprotein C-I
ARMC4 armadillo repeat containing 4
C14ORF1 chromosome 14 open reading frame 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD22 CD22 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFAP45 cilia and flagella associated protein 45
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN4 chloride channel, voltage-sensitive 4
CLDN17 claudin 17
COL7A1 collagen, type VII, alpha 1
COL8A2 collagen, type VIII, alpha 2
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTRC chymotrypsin C (caldecrin)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAPK2 death-associated protein kinase 2
DBF4B DBF4 zinc finger B
DEFA4 defensin, alpha 4, corticostatin
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
ETV1 ets variant 1
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGF17 fibroblast growth factor 17
FHL1 four and a half LIM domains 1
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
HABP2 hyaluronan binding protein 2
HBS1L HBS1-like translational GTPase
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HR hair growth associated
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNA14 interferon, alpha 14
IL1RN interleukin 1 receptor antagonist
IL36G interleukin 36, gamma
ITGB6 integrin, beta 6
KHSRP KH-type splicing regulatory protein
KLF13 Kruppel-like factor 13
KLRC4 killer cell lectin-like receptor subfamily C, member 4
KRT2 keratin 2, type II
LINC00341 long intergenic non-protein coding RNA 341
LOC157562 uncharacterized LOC157562
LYZL6 lysozyme-like 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
MEP1B meprin A, beta
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDRG2 NDRG family member 2
NELL2 NEL-like 2 (chicken)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NKX2-5 NK2 homeobox 5
NPY neuropeptide Y
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRAP nebulin-related anchoring protein
NUDCD3 NudC domain containing 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGFR opioid growth factor receptor
OPRL1 opiate receptor-like 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH1 protocadherin 1
PCDHB17P protocadherin beta 17 pseudogene
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER1 period circadian clock 1
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEK pleckstrin
PLTP phospholipid transfer protein
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
RAD52 RAD52 homolog (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS3 RNA binding motif, single stranded interacting protein 3
RSU1 Ras suppressor protein 1
RYR1 ryanodine receptor 1 (skeletal)
S100A1 S100 calcium binding protein A1
SAA3P serum amyloid A3 pseudogene
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SOD3 superoxide dismutase 3, extracellular
SOGA1 suppressor of glucose, autophagy associated 1
SYN2 synapsin II
TBC1D2 TBC1 domain family, member 2
TBXA2R thromboxane A2 receptor
TGFA transforming growth factor, alpha
TMEM63A transmembrane protein 63A
TMOD1 tropomodulin 1
TONSL tonsoku-like, DNA repair protein
TPMT thiopurine S-methyltransferase
TTLL3 tubulin tyrosine ligase-like family member 3
TUBA8 tubulin, alpha 8
USP2 ubiquitin specific peptidase 2
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
AIRE autoimmune regulator
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOD apolipoprotein D
ARHGAP4 Rho GTPase activating protein 4
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
BMP10 bone morphogenetic protein 10
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF21 chromosome 11 open reading frame 21
C11ORF80 chromosome 11 open reading frame 80
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5ORF45 chromosome 5 open reading frame 45
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CLSTN2 calsyntenin 2
CTSK cathepsin K
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK2 docking protein 2, 56kDa
DOK5 docking protein 5
ERCC4 excision repair cross-complementation group 4
ERN1 endoplasmic reticulum to nucleus signaling 1
FGF13 fibroblast growth factor 13
FSCN1 fascin actin-bundling protein 1
GID4 GID complex subunit 4
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTTP1 glutathione S-transferase theta pseudogene 1
HIST1H1E histone cluster 1, H1e
HIST1H3E histone cluster 1, H3e
HIST1H4D histone cluster 1, H4d
HMGB3P1 high mobility group box 3 pseudogene 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
ITM2C integral membrane protein 2C
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM7A lysine (K)-specific demethylase 7A
KIF4A kinesin family member 4A
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LMAN2L lectin, mannose-binding 2-like
MAGEA5 melanoma antigen family A5
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MOB3B MOB kinase activator 3B
MPDU1 mannose-P-dolichol utilization defect 1
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NYNRIN NYN domain and retroviral integrase containing
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR3 progestin and adipoQ receptor family member III
PARD6A par-6 family cell polarity regulator alpha
PCDHA5 protocadherin alpha 5
PGR progesterone receptor
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PVRL3 poliovirus receptor-related 3
QPCTL glutaminyl-peptide cyclotransferase-like
QSER1 glutamine and serine rich 1
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB8B RAB8B, member RAS oncogene family
RBM4B RNA binding motif protein 4B
RGS2 regulator of G-protein signaling 2
RLN1 relaxin 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL13P5 ribosomal protein L13 pseudogene 5
RRAGB Ras-related GTP binding B
SERGEF secretion regulating guanine nucleotide exchange factor
SLC12A9 solute carrier family 12, member 9
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SP1 Sp1 transcription factor
SPC25 SPC25, NDC80 kinetochore complex component
STRN striatin, calmodulin binding protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM242 transmembrane protein 242
UPP1 uridine phosphorylase 1
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WDR76 WD repeat domain 76
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF16 zinc finger protein 16
ZNF165 zinc finger protein 165
ZNF532 zinc finger protein 532
ZNF767P zinc finger family member 767, pseudogene