PNU-0230031-3732 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the PNU-0230031-3732 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
ACTN2 actinin, alpha 2
ADAM28 ADAM metallopeptidase domain 28
APAF1 apoptotic peptidase activating factor 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BAIAP3 BAI1-associated protein 3
BBC3 BCL2 binding component 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF63 chromosome 11 open reading frame 63
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF72 chromosome 2 open reading frame 72
CARF calcium responsive transcription factor
CARTPT CART prepropeptide
CDC25C cell division cycle 25C
CDHR2 cadherin-related family member 2
CDO1 cysteine dioxygenase type 1
CEL carboxyl ester lipase
CLEC3B C-type lectin domain family 3, member B
COPE coatomer protein complex, subunit epsilon
DACH1 dachshund family transcription factor 1
DNAH17 dynein, axonemal, heavy chain 17
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPY19L1P1 DPY19L1 pseudogene 1
DVL2 dishevelled segment polarity protein 2
EPHA5 EPH receptor A5
ESR1 estrogen receptor 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM110D family with sequence similarity 110, member D
FAM184A family with sequence similarity 184, member A
FANCA Fanconi anemia, complementation group A
FBXO40 F-box protein 40
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLJ22184
FLJ42627 uncharacterized LOC645644
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GHRH growth hormone releasing hormone
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR19 G protein-coupled receptor 19
GSPT1 G1 to S phase transition 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IDS iduronate 2-sulfatase
IL32 interleukin 32
IL36G interleukin 36, gamma
INADL InaD-like (Drosophila)
ITPKA inositol-trisphosphate 3-kinase A
KCTD14 potassium channel tetramerization domain containing 14
KIFC3 kinesin family member C3
LOC157562 uncharacterized LOC157562
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
MAPK11 mitogen-activated protein kinase 11
MCF2L MCF.2 cell line derived transforming sequence-like
MEF2D myocyte enhancer factor 2D
MEGF6 multiple EGF-like-domains 6
MST1 macrophage stimulating 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
N4BP2L1 NEDD4 binding protein 2-like 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NEK9 NIMA-related kinase 9
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NME5 NME/NM23 family member 5
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NUP214 nucleoporin 214kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PEX16 peroxisomal biogenesis factor 16
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POM121L2 POM121 transmembrane nucleoporin-like 2
POU2F2 POU class 2 homeobox 2
PRB3 proline-rich protein BstNI subfamily 3
PRDX2 peroxiredoxin 2
PROL1 proline rich, lacrimal 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
R3HCC1L R3H domain and coiled-coil containing 1-like
RASL11B RAS-like, family 11, member B
RBM17 RNA binding motif protein 17
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RGS5 regulator of G-protein signaling 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SSTR4 somatostatin receptor 4
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYCE1L synaptonemal complex central element protein 1-like
TADA2A transcriptional adaptor 2A
TAOK2 TAO kinase 2
TET3 tet methylcytosine dioxygenase 3
TFEB transcription factor EB
TK2 thymidine kinase 2, mitochondrial
TLDC1 TBC/LysM-associated domain containing 1
TSPAN32 tetraspanin 32
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZNF154 zinc finger protein 154
ZNF219 zinc finger protein 219
ZNF280B zinc finger protein 280B
ZNF667 zinc finger protein 667

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ADAM23 ADAM metallopeptidase domain 23
ADTRP androgen-dependent TFPI-regulating protein
AHSG alpha-2-HS-glycoprotein
AK5 adenylate kinase 5
AKR1C2 aldo-keto reductase family 1, member C2
ARHGAP24 Rho GTPase activating protein 24
ARMCX2 armadillo repeat containing, X-linked 2
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF54 chromosome 1 open reading frame 54
C9ORF3 chromosome 9 open reading frame 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDH19 cadherin 19, type 2
CDH7 cadherin 7, type 2
CENPE centromere protein E, 312kDa
CES3 carboxylesterase 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRMP1 collapsin response mediator protein 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DDN dendrin
DSPP dentin sialophosphoprotein
DYM dymeclin
ELSPBP1 epididymal sperm binding protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
FGL1 fibrinogen-like 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAN gigaxonin
GBP2 guanylate binding protein 2, interferon-inducible
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GRB7 growth factor receptor-bound protein 7
H1F0 H1 histone family, member 0
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BB histone cluster 1, H2bb
HIST1H3C histone cluster 1, H3c
HIST1H4E histone cluster 1, H4e
HOXB9 homeobox B9
IFT54 intraflagellar transport 54
IL7 interleukin 7
INCENP inner centromere protein antigens 135/155kDa
INE1 inactivation escape 1 (non-protein coding)
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KLHL25 kelch-like family member 25
LIMD2 LIM domain containing 2
LINC00312 long intergenic non-protein coding RNA 312
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MAP3K7CL MAP3K7 C-terminal like
MDM4 MDM4, p53 regulator
MLYCD malonyl-CoA decarboxylase
MYOZ3 myozenin 3
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPHP1 nephronophthisis 1 (juvenile)
PACS1 phosphofurin acidic cluster sorting protein 1
PGLYRP4 peptidoglycan recognition protein 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK1 polo-like kinase 1
POLL polymerase (DNA directed), lambda
PRAMEF11 PRAME family member 11
PSRC1 proline/serine-rich coiled-coil 1
PTPRS protein tyrosine phosphatase, receptor type, S
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB30 RAB30, member RAS oncogene family
RFPL3 ret finger protein-like 3
RLN1 relaxin 1
ROM1 retinal outer segment membrane protein 1
SAYSD1 SAYSVFN motif domain containing 1
SFT2D2 SFT2 domain containing 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIX3 SIX homeobox 3
SLC16A6 solute carrier family 16, member 6
SLC22A14 solute carrier family 22, member 14
SLC22A18 solute carrier family 22, member 18
SLC46A3 solute carrier family 46, member 3
SNRPN small nuclear ribonucleoprotein polypeptide N
SPANXC SPANX family, member C
STRN striatin, calmodulin binding protein
TCP10 t-complex 10
TESPA1 thymocyte expressed, positive selection associated 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM159 transmembrane protein 159
TNS4 tensin 4
TRAC T cell receptor alpha constant
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
ZFHX3 zinc finger homeobox 3
ZNF639 zinc finger protein 639
ZNF749 zinc finger protein 749