PNU-0230031-3735 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the PNU-0230031-3735 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAGAB alpha- and gamma-adaptin binding protein
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACE2 angiotensin I converting enzyme 2
ADGRL3 adhesion G protein-coupled receptor L3
AMELX amelogenin, X-linked
ATG10 autophagy related 10
ATP10A ATPase, class V, type 10A
BAIAP2 BAI1-associated protein 2
BBS9 Bardet-Biedl syndrome 9
BMP7 bone morphogenetic protein 7
C18ORF25 chromosome 18 open reading frame 25
C1ORF68 chromosome 1 open reading frame 68
C21ORF2 chromosome 21 open reading frame 2
CALD1 caldesmon 1
CD2 CD2 molecule
CD33 CD33 molecule
CDC25C cell division cycle 25C
CEL carboxyl ester lipase
CFAP45 cilia and flagella associated protein 45
CHAT choline O-acetyltransferase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCN4 chloride channel, voltage-sensitive 4
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DNAAF1 dynein, axonemal, assembly factor 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ESR1 estrogen receptor 1
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EXOSC1 exosome component 1
EXPH5 exophilin 5
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FNDC3A fibronectin type III domain containing 3A
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPC3 glypican 3
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPNMB glycoprotein (transmembrane) nmb
GPR182 G protein-coupled receptor 182
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IGLJ3 immunoglobulin lambda joining 3
IQCK IQ motif containing K
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KIAA1109 KIAA1109
KIF25 kinesin family member 25
KLHL22 kelch-like family member 22
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LAMA2 laminin, alpha 2
LIMK2 LIM domain kinase 2
LZTS1 leucine zipper, putative tumor suppressor 1
MAPK8 mitogen-activated protein kinase 8
MNMIP1 manchette microtubule inner protein 1
MRC2 mannose receptor, C type 2
MYH14 myosin, heavy chain 14, non-muscle
N4BP2L1 NEDD4 binding protein 2-like 1
NTF3 neurotrophin 3
OCLM oculomedin
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLXND1 plexin D1
PNMAL1 paraneoplastic Ma antigen family-like 1
PQLC2 PQ loop repeat containing 2
PRDX2 peroxiredoxin 2
PRKCE protein kinase C, epsilon
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RGS4 regulator of G-protein signaling 4
RUNDC3A RUN domain containing 3A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN3B sodium channel, voltage gated, type III beta subunit
SRCAP Snf2-related CREBBP activator protein
SRRT serrate, RNA effector molecule
SSX1 synovial sarcoma, X breakpoint 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TAS2R10 taste receptor, type 2, member 10
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TM4SF20 transmembrane 4 L six family member 20
TRAPPC9 trafficking protein particle complex 9
TRIM29 tripartite motif containing 29
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TUBA3C tubulin, alpha 3c
TULP2 tubby like protein 2
UBXN1 UBX domain protein 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UST uronyl-2-sulfotransferase
VAMP5 vesicle-associated membrane protein 5
ZBTB6 zinc finger and BTB domain containing 6
ZFP64 ZFP64 zinc finger protein
ZNF219 zinc finger protein 219
ZNF287 zinc finger protein 287
ZNF345 zinc finger protein 345

decreased expression

Symbol Name
AK5 adenylate kinase 5
ALPP alkaline phosphatase, placental
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOL6 apolipoprotein L, 6
ARMCX4 armadillo repeat containing, X-linked 4
ASIC3 acid sensing (proton gated) ion channel 3
AURKC aurora kinase C
BBS7 Bardet-Biedl syndrome 7
BEND5 BEN domain containing 5
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5 complement component 5
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNPY4 canopy FGF signaling regulator 4
CPZ carboxypeptidase Z
CYB5R2 cytochrome b5 reductase 2
CYBRD1 cytochrome b reductase 1
DEXI Dexi homolog (mouse)
DIO3 deiodinase, iodothyronine, type III
DMTN dematin actin binding protein
DOK5 docking protein 5
DPF3 D4, zinc and double PHD fingers, family 3
DSPP dentin sialophosphoprotein
DYM dymeclin
EFNA3 ephrin-A3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPHA4 EPH receptor A4
EPN3 epsin 3
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FPGS folylpolyglutamate synthase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIRA histone cell cycle regulator
HIST1H2BM histone cluster 1, H2bm
HIST1H4E histone cluster 1, H4e
HLA-DMA major histocompatibility complex, class II, DM alpha
HPN hepsin
IKZF5 IKAROS family zinc finger 5 (Pegasus)
LIME1 Lck interacting transmembrane adaptor 1
LIPG lipase, endothelial
LRP3 low density lipoprotein receptor-related protein 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MARK1 MAP/microtubule affinity-regulating kinase 1
MCOLN3 mucolipin 3
MDFI MyoD family inhibitor
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MYOZ3 myozenin 3
NELL2 NEL-like 2 (chicken)
NPFFR1 neuropeptide FF receptor 1
NTSR1 neurotensin receptor 1 (high affinity)
NXPH4 neurexophilin 4
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCDHA9 protocadherin alpha 9
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRSS22 protease, serine, 22
RAB36 RAB36, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
ROM1 retinal outer segment membrane protein 1
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLN sarcolipin
SMO smoothened, frizzled class receptor
SOBP sine oculis binding protein homolog (Drosophila)
SPATA2L spermatogenesis associated 2-like
SPTBN2 spectrin, beta, non-erythrocytic 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D2 TBC1 domain family, member 2
TESPA1 thymocyte expressed, positive selection associated 1
THRB thyroid hormone receptor, beta
WDR33 WD repeat domain 33
ZBTB3 zinc finger and BTB domain containing 3
ZC2HC1C zinc finger, C2HC-type containing 1C
ZC3H12A zinc finger CCCH-type containing 12A
ZNF32 zinc finger protein 32
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862