PNU-0230031-4288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the PNU-0230031-4288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
AMPH amphiphysin
ARID5A AT rich interactive domain 5A (MRF1-like)
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
ATP10B ATPase, class V, type 10B
BMPR1B bone morphogenetic protein receptor, type IB
C14ORF93 chromosome 14 open reading frame 93
C21ORF2 chromosome 21 open reading frame 2
CADM1 cell adhesion molecule 1
CADM3 cell adhesion molecule 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASZ1 castor zinc finger 1
CCDC40 coiled-coil domain containing 40
CCNK cyclin K
CD3D CD3d molecule, delta (CD3-TCR complex)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCN7 chloride channel, voltage-sensitive 7
CLEC4A C-type lectin domain family 4, member A
COL16A1 collagen, type XVI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSF1 colony stimulating factor 1 (macrophage)
CUL3 cullin 3
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DEFA5 defensin, alpha 5, Paneth cell-specific
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DST dystonin
DZIP1 DAZ interacting zinc finger protein 1
ESRRG estrogen-related receptor gamma
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM63A family with sequence similarity 63, member A
FGB fibrinogen beta chain
FLJ22184
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GPR135 G protein-coupled receptor 135
HRG histidine-rich glycoprotein
IL36G interleukin 36, gamma
JAG1 jagged 1
JUN jun proto-oncogene
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL22 kelch-like family member 22
KLHL24 kelch-like family member 24
KRT38 keratin 38, type I
LAMA4 laminin, alpha 4
LMX1B LIM homeobox transcription factor 1, beta
LOC157562 uncharacterized LOC157562
LPP LIM domain containing preferred translocation partner in lipoma
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK11 mitogen-activated protein kinase 11
MAU2 MAU2 sister chromatid cohesion factor
MED18 mediator complex subunit 18
MR1 major histocompatibility complex, class I-related
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NEBL nebulette
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKTR natural killer cell triggering receptor
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTM neurotrimin
NUP54 nucleoporin 54kDa
OBSL1 obscurin-like 1
ONECUT2 one cut homeobox 2
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PDCD6 programmed cell death 6
PDE4C phosphodiesterase 4C, cAMP-specific
PKP4 plakophilin 4
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PQBP1 polyglutamine binding protein 1
PTCH2 patched 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
RIBC2 RIB43A domain with coiled-coils 2
RPL23AP53 ribosomal protein L23a pseudogene 53
RRH retinal pigment epithelium-derived rhodopsin homolog
SH3BP2 SH3-domain binding protein 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SRPX2 sushi-repeat containing protein, X-linked 2
SRRT serrate, RNA effector molecule
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUGP1 SURP and G patch domain containing 1
SULF1 sulfatase 1
SZRD1 SUZ RNA binding domain containing 1
TAPBP TAP binding protein (tapasin)
TAS2R1 taste receptor, type 2, member 1
THOC5 THO complex 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPO thymopoietin
VCL vinculin
ZC3H11A zinc finger CCCH-type containing 11A
ZIM2 zinc finger, imprinted 2
ZNF345 zinc finger protein 345
ZNF749 zinc finger protein 749
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFF4 AF4/FMR2 family, member 4
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARMCX2 armadillo repeat containing, X-linked 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAHCC1 BAH domain and coiled-coil containing 1
BCL2L2 BCL2-like 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF80 chromosome 17 open reading frame 80
C1S complement component 1, s subcomponent
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBY1 chibby homolog 1 (Drosophila)
CCDC132 coiled-coil domain containing 132
CISH cytokine inducible SH2-containing protein
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CLEC2B C-type lectin domain family 2, member B
CRMP1 collapsin response mediator protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTGF connective tissue growth factor
CYB5R4 cytochrome b5 reductase 4
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAAF2 dynein, axonemal, assembly factor 2
ELSPBP1 epididymal sperm binding protein 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EXOC5 exocyst complex component 5
FAM105A family with sequence similarity 105, member A
FAM64A family with sequence similarity 64, member A
FANCF Fanconi anemia, complementation group F
FBXO22 F-box protein 22
FGF23 fibroblast growth factor 23
FZD3 frizzled class receptor 3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GBX2 gastrulation brain homeobox 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRAMD3 GRAM domain containing 3
GRPR gastrin-releasing peptide receptor
H1F0 H1 histone family, member 0
HIST1H3A histone cluster 1, H3a
HOXC13 homeobox C13
HOXC5 homeobox C5
HP1BP3 heterochromatin protein 1, binding protein 3
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA0319L KIAA0319-like
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LIPG lipase, endothelial
LMTK1 lemur tail kinase 1
MAGEA5 melanoma antigen family A5
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
MPP1 membrane protein, palmitoylated 1, 55kDa
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPR3 natriuretic peptide receptor 3
ODF2 outer dense fiber of sperm tails 2
OSMR oncostatin M receptor
PAQR3 progestin and adipoQ receptor family member III
PARN poly(A)-specific ribonuclease
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLK1 polo-like kinase 1
PLXNB3 plexin B3
POLL polymerase (DNA directed), lambda
PRB3 proline-rich protein BstNI subfamily 3
PROX1 prospero homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRS protein tyrosine phosphatase, receptor type, S
PTPRU protein tyrosine phosphatase, receptor type, U
PWAR5 Prader Willi/Angelman region RNA 5
R3HCC1L R3H domain and coiled-coil containing 1-like
RBM42 RNA binding motif protein 42
RNF122 ring finger protein 122
SENP7 SUMO1/sentrin specific peptidase 7
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPC25 SPC25, NDC80 kinetochore complex component
SSBP3 single stranded DNA binding protein 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN transgelin
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TTC30A tetratricopeptide repeat domain 30A
TWSG1 twisted gastrulation BMP signaling modulator 1
YIPF5 Yip1 domain family, member 5
ZFHX3 zinc finger homeobox 3
ZNF165 zinc finger protein 165
ZNF711 zinc finger protein 711
ZW10 zw10 kinetochore protein