PNU-0230031-4754 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the PNU-0230031-4754 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM20 ADAM metallopeptidase domain 20
AKAP7 A kinase (PRKA) anchor protein 7
AKT3 v-akt murine thymoma viral oncogene homolog 3
AMPD3 adenosine monophosphate deaminase 3
B9D1 B9 protein domain 1
BARX2 BARX homeobox 2
C14ORF105 chromosome 14 open reading frame 105
C3ORF18 chromosome 3 open reading frame 18
C7ORF69 chromosome 7 open reading frame 69
CARD10 caspase recruitment domain family, member 10
CD52 CD52 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKL3 cyclin-dependent kinase-like 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L2 chitinase 3-like 2
CHN2 chimerin 2
CNN3 calponin 3, acidic
COL1A1 collagen, type I, alpha 1
CRYAB crystallin, alpha B
CRYGC crystallin, gamma C
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGCR8 DGCR8 microprocessor complex subunit
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUOX1 dual oxidase 1
EFR3B EFR3 homolog B (S. cerevisiae)
EGR1 early growth response 1
EHD2 EH-domain containing 2
EPHB1 EPH receptor B1
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL8 F-box and leucine-rich repeat protein 8
FHL1 four and a half LIM domains 1
GFI1 growth factor independent 1 transcription repressor
GLIPR1 GLI pathogenesis-related 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC3 glypican 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRK4 G protein-coupled receptor kinase 4
GSTP1 glutathione S-transferase pi 1
HEG1 heart development protein with EGF-like domains 1
HIST1H3B histone cluster 1, H3b
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA10 homeobox A10
HPR haptoglobin-related protein
IGHMBP2 immunoglobulin mu binding protein 2
IL1RN interleukin 1 receptor antagonist
ITGB6 integrin, beta 6
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KLF13 Kruppel-like factor 13
KRT15 keratin 15, type I
LECT1 leukocyte cell derived chemotaxin 1
LOC157562 uncharacterized LOC157562
MAP1A microtubule-associated protein 1A
MED25 mediator complex subunit 25
MOBP myelin-associated oligodendrocyte basic protein
MUC3A mucin 3A, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAG18 NAG18 mRNA
NCKIPSD NCK interacting protein with SH3 domain
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
NXF2 nuclear RNA export factor 2
OLFM4 olfactomedin 4
PACRG PARK2 co-regulated
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX2 paired box 2
PBOV1 prostate and breast cancer overexpressed 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER1 period circadian clock 1
PLAC4 placenta-specific 4
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNC1 plexin C1
POU2F2 POU class 2 homeobox 2
PRM2 protamine 2
PTHLH parathyroid hormone-like hormone
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM12B RNA binding motif protein 12B
RGS12 regulator of G-protein signaling 12
RHBG Rh family, B glycoprotein (gene/pseudogene)
RUSC2 RUN and SH3 domain containing 2
SARM1 sterile alpha and TIR motif containing 1
SATB2 SATB homeobox 2
SKI SKI proto-oncogene
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOGA1 suppressor of glucose, autophagy associated 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THOC5 THO complex 5
TMPRSS4 transmembrane protease, serine 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
USP46 ubiquitin specific peptidase 46
ZNF415 zinc finger protein 415
ZNF44 zinc finger protein 44
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD14A abhydrolase domain containing 14A
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
ADM adrenomedullin
AKAP12 A kinase (PRKA) anchor protein 12
ARRB1 arrestin, beta 1
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C2ORF27A chromosome 2 open reading frame 27A
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CARF calcium responsive transcription factor
CD82 CD82 molecule
CD8A CD8a molecule
CENPO centromere protein O
CLEC7A C-type lectin domain family 7, member A
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
EHBP1L1 EH domain binding protein 1-like 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXD3 exonuclease 3'-5' domain containing 3
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM64A family with sequence similarity 64, member A
FFAR2 free fatty acid receptor 2
FNTB farnesyltransferase, CAAX box, beta
FRS2 fibroblast growth factor receptor substrate 2
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLCE glucuronic acid epimerase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AL histone cluster 1, H2al
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXC11 homeobox C11
HOXC13 homeobox C13
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
IL22 interleukin 22
KCTD7 potassium channel tetramerization domain containing 7
KITLG KIT ligand
LIG4 ligase IV, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
LINC00115 long intergenic non-protein coding RNA 115
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC390998 ribosomal protein L10 pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MEIS1 Meis homeobox 1
MFGE8 milk fat globule-EGF factor 8 protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPS18C mitochondrial ribosomal protein S18C
MTCP1 mature T-cell proliferation 1
NCALD neurocalcin delta
NHEJ1 nonhomologous end-joining factor 1
NKX3-2 NK3 homeobox 2
ONECUT1 one cut homeobox 1
PGR progesterone receptor
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD2 phospholipase D2
PRF1 perforin 1 (pore forming protein)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3A RAB3A, member RAS oncogene family
RAI2 retinoic acid induced 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPC25 SPC25, NDC80 kinetochore complex component
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TCTA T-cell leukemia translocation altered
TFF2 trefoil factor 2
TMEM62 transmembrane protein 62
TUBA3C tubulin, alpha 3c
VIPR1 vasoactive intestinal peptide receptor 1
WDR76 WD repeat domain 76
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB22 zinc finger and BTB domain containing 22
ZBTB33 zinc finger and BTB domain containing 33
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF16 zinc finger protein 16
ZNF350 zinc finger protein 350