PNU-0230031-4757 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the PNU-0230031-4757 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADRBK1 adrenergic, beta, receptor kinase 1
AMPH amphiphysin
ANGPTL2 angiopoietin-like 2
AQP1 aquaporin 1 (Colton blood group)
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCAN brevican
BMP10 bone morphogenetic protein 10
C1ORF54 chromosome 1 open reading frame 54
C7ORF69 chromosome 7 open reading frame 69
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CCDC81 coiled-coil domain containing 81
CCL27 chemokine (C-C motif) ligand 27
CDO1 cysteine dioxygenase type 1
CHM choroideremia (Rab escort protein 1)
CLTC clathrin, heavy chain (Hc)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DOK4 docking protein 4
EGFR epidermal growth factor receptor
EPHA3 EPH receptor A3
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM182B family with sequence similarity 182, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FHL1 four and a half LIM domains 1
FOXG1 forkhead box G1
G0S2 G0/G1 switch 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GHRHR growth hormone releasing hormone receptor
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR162 G protein-coupled receptor 162
GREB1L growth regulation by estrogen in breast cancer-like
GRM7 glutamate receptor, metabotropic 7
GTDC1 glycosyltransferase-like domain containing 1
HIPK3 homeodomain interacting protein kinase 3
HNF1B HNF1 homeobox B
IFT27 intraflagellar transport 27
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL11 interleukin 11
IL1B interleukin 1, beta
INSL4 insulin-like 4 (placenta)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JRK Jrk homolog (mouse)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KYNU kynureninase
LMTK1 lemur tail kinase 1
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK11 mitogen-activated protein kinase 11
MARK4 MAP/microtubule affinity-regulating kinase 4
MAU2 MAU2 sister chromatid cohesion factor
MR1 major histocompatibility complex, class I-related
MRPL20 mitochondrial ribosomal protein L20
MRPL41 mitochondrial ribosomal protein L41
MSR1 macrophage scavenger receptor 1
NLGN1 neuroligin 1
NOD1 nucleotide-binding oligomerization domain containing 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAWR PRKC, apoptosis, WT1, regulator
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PGLYRP4 peptidoglycan recognition protein 4
PLCD1 phospholipase C, delta 1
PPARD peroxisome proliferator-activated receptor delta
PRKCE protein kinase C, epsilon
PTGDR2 prostaglandin D2 receptor 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTH2R parathyroid hormone 2 receptor
PVR poliovirus receptor
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RARB retinoic acid receptor, beta
RPL35A ribosomal protein L35a
RSU1 Ras suppressor protein 1
RTEL1 regulator of telomere elongation helicase 1
RYR2 ryanodine receptor 2 (cardiac)
S100A7 S100 calcium binding protein A7
SH3GL3 SH3-domain GRB2-like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
STK3 serine/threonine kinase 3
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAGLN3 transgelin 3
TBC1D2 TBC1 domain family, member 2
TEX15 testis expressed 15
TEX40 testis expressed 40
TFEB transcription factor EB
THOC5 THO complex 5
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
WSB1 WD repeat and SOCS box containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF224 zinc finger protein 224

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADAP2 ArfGAP with dual PH domains 2
AGMAT agmatine ureohydrolase (agmatinase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BAGE B melanoma antigen
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD82 CD82 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CHMP6 charged multivesicular body protein 6
CIC capicua transcriptional repressor
CLCF1 cardiotrophin-like cytokine factor 1
CLDN1 claudin 1
CLEC7A C-type lectin domain family 7, member A
CLSTN2 calsyntenin 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DSPP dentin sialophosphoprotein
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
FAM110B family with sequence similarity 110, member B
FAM131A family with sequence similarity 131, member A
FAM46C family with sequence similarity 46, member C
FANCE Fanconi anemia, complementation group E
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF23 fibroblast growth factor 23
GBP2 guanylate binding protein 2, interferon-inducible
GLRA1 glycine receptor, alpha 1
GPX2 glutathione peroxidase 2
HCAR3 hydroxycarboxylic acid receptor 3
HCG4 HLA complex group 4 (non-protein coding)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HMHA1 histocompatibility (minor) HA-1
HPS6 Hermansky-Pudlak syndrome 6
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
INPP5J inositol polyphosphate-5-phosphatase J
IRF2BP1 interferon regulatory factor 2 binding protein 1
JMJD4 jumonji domain containing 4
KCTD17 potassium channel tetramerization domain containing 17
KDM8 lysine (K)-specific demethylase 8
LARP6 La ribonucleoprotein domain family, member 6
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIN7A lin-7 homolog A (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LTC4S leukotriene C4 synthase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MFGE8 milk fat globule-EGF factor 8 protein
MID1IP1 MID1 interacting protein 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MYL5 myosin, light chain 5, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NIPAL2 NIPA-like domain containing 2
NNAT neuronatin
NOL12 nucleolar protein 12
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NXN nucleoredoxin
NYNRIN NYN domain and retroviral integrase containing
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVOL1 ovo-like zinc finger 1
PAQR6 progestin and adipoQ receptor family member VI
PGR progesterone receptor
PRSS53 protease, serine, 53
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RPGR retinitis pigmentosa GTPase regulator
SAMD9 sterile alpha motif domain containing 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SRPX sushi-repeat containing protein, X-linked
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBX19 T-box 19
TBX3 T-box 3
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TTLL1 tubulin tyrosine ligase-like family member 1
UCN urocortin
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
WDR33 WD repeat domain 33
ZNF134 zinc finger protein 134
ZNF551 zinc finger protein 551
ZNF672 zinc finger protein 672
ZSCAN31 zinc finger and SCAN domain containing 31