| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the PNU-0293363-6563 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADA | adenosine deaminase |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APH1A | APH1A gamma secretase subunit |
| APOL2 | apolipoprotein L, 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| BAX | BCL2-associated X protein |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CABIN1 | calcineurin binding protein 1 |
| CACFD1 | calcium channel flower domain containing 1 |
| CDH8 | cadherin 8, type 2 |
| CIB2 | calcium and integrin binding family member 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DICER1 | dicer 1, ribonuclease type III |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EMC3 | ER membrane protein complex subunit 3 |
| EVA1B | eva-1 homolog B (C. elegans) |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBN2 | fibrillin 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLG1 | golgi glycoprotein 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HOMER2 | homer scaffolding protein 2 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXB5 | homeobox B5 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| KCTD14 | potassium channel tetramerization domain containing 14 |
| KHSRP | KH-type splicing regulatory protein |
| KIFC1 | kinesin family member C1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIMK1 | LIM domain kinase 1 |
| LMNB1 | lamin B1 |
| LOC157562 | uncharacterized LOC157562 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED25 | mediator complex subunit 25 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MYO19 | myosin XIX |
| NNAT | neuronatin |
| NRP2 | neuropilin 2 |
| OGDHL | oxoglutarate dehydrogenase-like |
| PARD3 | par-3 family cell polarity regulator |
| PCGF2 | polycomb group ring finger 2 |
| PER1 | period circadian clock 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB40B | RAB40B, member RAS oncogene family |
| RANGAP1 | Ran GTPase activating protein 1 |
| RBKS | ribokinase |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RGS10 | regulator of G-protein signaling 10 |
| RNF24 | ring finger protein 24 |
| RPL35A | ribosomal protein L35a |
| SAFB | scaffold attachment factor B |
| SCARB2 | scavenger receptor class B, member 2 |
| SGSM3 | small G protein signaling modulator 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SMOX | spermine oxidase |
| SND1-IT1 | SND1 intronic transcript 1 |
| STAC | SH3 and cysteine rich domain |
| TAZ | tafazzin |
| TMEM8B | transmembrane protein 8B |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM2 | tripartite motif containing 2 |
| TSPAN9 | tetraspanin 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| TUBA3C | tubulin, alpha 3c |
| WDR61 | WD repeat domain 61 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZNF444 | zinc finger protein 444 |
| ZNF580 | zinc finger protein 580 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AURKB | aurora kinase B |
| BBS7 | Bardet-Biedl syndrome 7 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CCNB1 | cyclin B1 |
| CCNB2 | cyclin B2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CENPE | centromere protein E, 312kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COMMD10 | COMM domain containing 10 |
| CTGF | connective tissue growth factor |
| DEPDC1 | DEP domain containing 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EMC6 | ER membrane protein complex subunit 6 |
| ESRP1 | epithelial splicing regulatory protein 1 |
| EXOC5 | exocyst complex component 5 |
| FAM186A | family with sequence similarity 186, member A |
| FAM188A | family with sequence similarity 188, member A |
| FAM64A | family with sequence similarity 64, member A |
| FUZ | fuzzy planar cell polarity protein |
| FZD3 | frizzled class receptor 3 |
| FZD8 | frizzled class receptor 8 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBAS | glioblastoma amplified sequence |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HLTF | helicase-like transcription factor |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXA1 | homeobox A1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICK | intestinal cell (MAK-like) kinase |
| KIAA0355 | KIAA0355 |
| KIF14 | kinesin family member 14 |
| KIF18A | kinesin family member 18A |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| MAGEA6 | melanoma antigen family A6 |
| MAGEF1 | melanoma antigen family F1 |
| MRPS27 | mitochondrial ribosomal protein S27 |
| MST1R | macrophage stimulating 1 receptor |
| MTMR6 | myotubularin related protein 6 |
| NECAP1 | NECAP endocytosis associated 1 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OCLN | occludin |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLAT | plasminogen activator, tissue |
| PLAU | plasminogen activator, urokinase |
| PLK1 | polo-like kinase 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAB23 | RAB23, member RAS oncogene family |
| RBM15B | RNA binding motif protein 15B |
| RBM4B | RNA binding motif protein 4B |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SELT | selenoprotein T |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC38A10 | solute carrier family 38, member 10 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| STIM1 | stromal interaction molecule 1 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM230 | transmembrane protein 230 |
| TMEM57 | transmembrane protein 57 |
| TPX2 | TPX2, microtubule-associated |
| TRIM52 | tripartite motif containing 52 |
| TSPAN8 | tetraspanin 8 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| WDR45B | WD repeat domain 45B |
| WDR5B | WD repeat domain 5B |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF177 | zinc finger protein 177 |
| ZNF324 | zinc finger protein 324 |
| ZNF654 | zinc finger protein 654 |
| ZNF665 | zinc finger protein 665 |
| ZNF701 | zinc finger protein 701 |