PNU-0293363-6563 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the PNU-0293363-6563 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACAD10 acyl-CoA dehydrogenase family, member 10
ADA adenosine deaminase
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APH1A APH1A gamma secretase subunit
APOL2 apolipoprotein L, 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGAP22 Rho GTPase activating protein 22
ARL14 ADP-ribosylation factor-like 14
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AVL9 AVL9 homolog (S. cerevisiase)
BAX BCL2-associated X protein
BTN2A2 butyrophilin, subfamily 2, member A2
C21ORF2 chromosome 21 open reading frame 2
C5ORF42 chromosome 5 open reading frame 42
CABIN1 calcineurin binding protein 1
CACFD1 calcium channel flower domain containing 1
CDH8 cadherin 8, type 2
CIB2 calcium and integrin binding family member 2
CLCN4 chloride channel, voltage-sensitive 4
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DICER1 dicer 1, ribonuclease type III
E2F4 E2F transcription factor 4, p107/p130-binding
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EMC3 ER membrane protein complex subunit 3
EVA1B eva-1 homolog B (C. elegans)
EYA4 EYA transcriptional coactivator and phosphatase 4
FBN2 fibrillin 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLG1 golgi glycoprotein 1
GPER1 G protein-coupled estrogen receptor 1
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HOMER2 homer scaffolding protein 2
HOOK1 hook microtubule-tethering protein 1
HOXB5 homeobox B5
HPS4 Hermansky-Pudlak syndrome 4
IGFBP5 insulin-like growth factor binding protein 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KCTD14 potassium channel tetramerization domain containing 14
KHSRP KH-type splicing regulatory protein
KIFC1 kinesin family member C1
LAT2 linker for activation of T cells family, member 2
LIME1 Lck interacting transmembrane adaptor 1
LIMK1 LIM domain kinase 1
LMNB1 lamin B1
LOC157562 uncharacterized LOC157562
LRRC37A3 leucine rich repeat containing 37, member A3
MANBA mannosidase, beta A, lysosomal
MAPK10 mitogen-activated protein kinase 10
MAPK12 mitogen-activated protein kinase 12
MED25 mediator complex subunit 25
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MYO19 myosin XIX
NNAT neuronatin
NRP2 neuropilin 2
OGDHL oxoglutarate dehydrogenase-like
PARD3 par-3 family cell polarity regulator
PCGF2 polycomb group ring finger 2
PER1 period circadian clock 1
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRH protein tyrosine phosphatase, receptor type, H
RAB40B RAB40B, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RBKS ribokinase
RBM3 RNA binding motif (RNP1, RRM) protein 3
RGS10 regulator of G-protein signaling 10
RNF24 ring finger protein 24
RPL35A ribosomal protein L35a
SAFB scaffold attachment factor B
SCARB2 scavenger receptor class B, member 2
SGSM3 small G protein signaling modulator 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SMG7 SMG7 nonsense mediated mRNA decay factor
SMOX spermine oxidase
SND1-IT1 SND1 intronic transcript 1
STAC SH3 and cysteine rich domain
TAZ tafazzin
TMEM8B transmembrane protein 8B
TPST2 tyrosylprotein sulfotransferase 2
TRAF2 TNF receptor-associated factor 2
TRIM2 tripartite motif containing 2
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
WDR61 WD repeat domain 61
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF444 zinc finger protein 444
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
ARID4A AT rich interactive domain 4A (RBP1-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AUH AU RNA binding protein/enoyl-CoA hydratase
AURKB aurora kinase B
BBS7 Bardet-Biedl syndrome 7
BTBD2 BTB (POZ) domain containing 2
CCNB1 cyclin B1
CCNB2 cyclin B2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPE centromere protein E, 312kDa
CHML choroideremia-like (Rab escort protein 2)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CKS2 CDC28 protein kinase regulatory subunit 2
CLCF1 cardiotrophin-like cytokine factor 1
COMMD10 COMM domain containing 10
CTGF connective tissue growth factor
DEPDC1 DEP domain containing 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EMC6 ER membrane protein complex subunit 6
ESRP1 epithelial splicing regulatory protein 1
EXOC5 exocyst complex component 5
FAM186A family with sequence similarity 186, member A
FAM188A family with sequence similarity 188, member A
FAM64A family with sequence similarity 64, member A
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
FZD8 frizzled class receptor 8
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GBAS glioblastoma amplified sequence
GDE1 glycerophosphodiester phosphodiesterase 1
HIST1H2AG histone cluster 1, H2ag
HLTF helicase-like transcription factor
HMMR hyaluronan-mediated motility receptor (RHAMM)
HOXA1 homeobox A1
HYAL3 hyaluronoglucosaminidase 3
ICK intestinal cell (MAK-like) kinase
KIAA0355 KIAA0355
KIF14 kinesin family member 14
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KIF23 kinesin family member 23
MAGEA6 melanoma antigen family A6
MAGEF1 melanoma antigen family F1
MRPS27 mitochondrial ribosomal protein S27
MST1R macrophage stimulating 1 receptor
MTMR6 myotubularin related protein 6
NECAP1 NECAP endocytosis associated 1
NEU1 sialidase 1 (lysosomal sialidase)
NOL6 nucleolar protein 6 (RNA-associated)
OCLN occludin
PACS1 phosphofurin acidic cluster sorting protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLK1 polo-like kinase 1
PNRC1 proline-rich nuclear receptor coactivator 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POMT1 protein-O-mannosyltransferase 1
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PSAT1 phosphoserine aminotransferase 1
PSRC1 proline/serine-rich coiled-coil 1
RAB23 RAB23, member RAS oncogene family
RBM15B RNA binding motif protein 15B
RBM4B RNA binding motif protein 4B
RPE ribulose-5-phosphate-3-epimerase
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SAMD9 sterile alpha motif domain containing 9
SCML1 sex comb on midleg-like 1 (Drosophila)
SELT selenoprotein T
SLC35A5 solute carrier family 35, member A5
SLC38A10 solute carrier family 38, member 10
SPDL1 spindle apparatus coiled-coil protein 1
STIM1 stromal interaction molecule 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM230 transmembrane protein 230
TMEM57 transmembrane protein 57
TPX2 TPX2, microtubule-associated
TRIM52 tripartite motif containing 52
TSPAN8 tetraspanin 8
TTPAL tocopherol (alpha) transfer protein-like
WDR45B WD repeat domain 45B
WDR5B WD repeat domain 5B
ZBTB10 zinc finger and BTB domain containing 10
ZBTB25 zinc finger and BTB domain containing 25
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF177 zinc finger protein 177
ZNF324 zinc finger protein 324
ZNF654 zinc finger protein 654
ZNF665 zinc finger protein 665
ZNF701 zinc finger protein 701