PNU-0293363-6568 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the PNU-0293363-6568 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA10 annexin A10
AP1AR adaptor-related protein complex 1 associated regulatory protein
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BMPR1A bone morphogenetic protein receptor, type IA
C14ORF1 chromosome 14 open reading frame 1
C16ORF59 chromosome 16 open reading frame 59
CALD1 caldesmon 1
CALU calumenin
CASKIN2 CASK interacting protein 2
CCNE2 cyclin E2
CCNL2 cyclin L2
CLDN3 claudin 3
CLIP1 CAP-GLY domain containing linker protein 1
CNTNAP2 contactin associated protein-like 2
COMMD10 COMM domain containing 10
CORO2A coronin, actin binding protein, 2A
CPQ carboxypeptidase Q
CRTC1 CREB regulated transcription coactivator 1
DBT dihydrolipoamide branched chain transacylase E2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DOCK10 dedicator of cytokinesis 10
ENO1 enolase 1, (alpha)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBN2 fibrillin 2
FH fumarate hydratase
GDE1 glycerophosphodiester phosphodiesterase 1
GPHN gephyrin
GPM6B glycoprotein M6B
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIC2 hypermethylated in cancer 2
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOOK1 hook microtubule-tethering protein 1
IL1RAP interleukin 1 receptor accessory protein
KDM4C lysine (K)-specific demethylase 4C
KIAA0754 KIAA0754
KIF16B kinesin family member 16B
KIRREL kin of IRRE like (Drosophila)
LRRC14 leucine rich repeat containing 14
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA2 lysophospholipase II
MAGEF1 melanoma antigen family F1
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MECR mitochondrial trans-2-enoyl-CoA reductase
MPDZ multiple PDZ domain protein
MPZL1 myelin protein zero-like 1
MSH6 mutS homolog 6
NCK1 NCK adaptor protein 1
NFIB nuclear factor I/B
NHEJ1 nonhomologous end-joining factor 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
OVGP1 oviductal glycoprotein 1, 120kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4DIP phosphodiesterase 4D interacting protein
PHC1 polyhomeotic homolog 1 (Drosophila)
PICALM phosphatidylinositol binding clathrin assembly protein
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEC plectin
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT2 protein arginine methyltransferase 2
PRNP prion protein
PSAT1 phosphoserine aminotransferase 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RHOBTB2 Rho-related BTB domain containing 2
RNF126 ring finger protein 126
RNF24 ring finger protein 24
RPL31 ribosomal protein L31
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SENP6 SUMO1/sentrin specific peptidase 6
SF3A1 splicing factor 3a, subunit 1, 120kDa
SMG7 SMG7 nonsense mediated mRNA decay factor
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TGM2 transglutaminase 2
TMCC1 transmembrane and coiled-coil domain family 1
TMEM230 transmembrane protein 230
TMEM231 transmembrane protein 231
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TRIM14 tripartite motif containing 14
TSKU tsukushi, small leucine rich proteoglycan
TSPAN4 tetraspanin 4
UBE4B ubiquitination factor E4B
USB1 U6 snRNA biogenesis 1
USP22 ubiquitin specific peptidase 22
WHSC1 Wolf-Hirschhorn syndrome candidate 1
ZBTB1 zinc finger and BTB domain containing 1
ZNF148 zinc finger protein 148
ZNF180 zinc finger protein 180
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASB7 ankyrin repeat and SOCS box containing 7
C7ORF43 chromosome 7 open reading frame 43
C9ORF114 chromosome 9 open reading frame 114
C9ORF40 chromosome 9 open reading frame 40
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDCA3 cell division cycle associated 3
CDK3 cyclin-dependent kinase 3
CENPE centromere protein E, 312kDa
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCA1 chloride channel accessory 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CRYL1 crystallin, lambda 1
CST4 cystatin S
CUL9 cullin 9
DBF4B DBF4 zinc finger B
DDIT3 DNA-damage-inducible transcript 3
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMBT1 deleted in malignant brain tumors 1
DSPP dentin sialophosphoprotein
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM64A family with sequence similarity 64, member A
FGL1 fibrinogen-like 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
H1F0 H1 histone family, member 0
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4C histone cluster 1, H4c
HIST2H2BE histone cluster 2, H2be
IGFLR1 IGF-like family receptor 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPAD1 inositol monophosphatase domain containing 1
INF2 inverted formin, FH2 and WH2 domain containing
IRAK4 interleukin-1 receptor-associated kinase 4
KIF20A kinesin family member 20A
LMBR1L limb development membrane protein 1-like
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRK1 leucine-rich repeat kinase 1
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MILR1 mast cell immunoglobulin-like receptor 1
MMP13 matrix metallopeptidase 13
MMRN2 multimerin 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MST1R macrophage stimulating 1 receptor
MTCH2 mitochondrial carrier 2
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
NCAPD2 non-SMC condensin I complex, subunit D2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NT5DC3 5'-nucleotidase domain containing 3
PCDH12 protocadherin 12
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDE12 phosphodiesterase 12
PIGG phosphatidylinositol glycan anchor biosynthesis, class G
PMCH pro-melanin-concentrating hormone
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODNL1 podocan-like 1
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRR15L proline rich 15-like
PSRC1 proline/serine-rich coiled-coil 1
RPL13P5 ribosomal protein L13 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SIRT2 sirtuin 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPAG4 sperm associated antigen 4
SPRR2B small proline-rich protein 2B
TACC3 transforming, acidic coiled-coil containing protein 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TMC5 transmembrane channel-like 5
TMC7 transmembrane channel-like 7
TMEM132A transmembrane protein 132A
TMEM57 transmembrane protein 57
TROAP trophinin associated protein
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
UNC13A unc-13 homolog A (C. elegans)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR13 WD repeat domain 13
WDR91 WD repeat domain 91
WFDC2 WAP four-disulfide core domain 2
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZNF165 zinc finger protein 165
ZNF701 zinc finger protein 701
ZNRD1-AS1 ZNRD1 antisense RNA 1